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Class 424/259.1 - Klebsiella (e.g., Klebsiella pneumoniae, etc.)


Subclass of Class 424 - Drug, bio-affecting and body treating compositions
Definition: Subject matter wherein the bacterium is of the genus Klebsiella.
No. of patents: 32
Last issue date: 10/11/2011


NumberTitleIssue Date
8034359Tissue targeted antigenic activation of the immune response to cancers
The invention provides in part methods of treating cancers of a specific organ or tissue by administering a composition that is antigenically specific for one or more microbes that are pathogenic in the specific organ or tissue in which the cancer is situated. The f...
10/11/2011
7408044Carrier protein having an adjuvant effect
The invention relates to an adjuvant product which is intended to improve the activity of a molecule when administered to a host, characterized in that it comprises at least one part of the P40 protein of Klebsiella pneumoniae or a protein having at least 80% homolo...
08/05/2008
7371393Methods for reducing fecal shedding
The present invention provides methods for reducing shedding in an animal. Generally, the method includes administcriirn to an animal a composition including siderophore receptor polypeptides and porins from gram negative microbes, and preferably, lipopolysaccarhide...
05/13/2008
7341732Methods for treating mastitis in a milk producing animal
The present invention provides methods for treating mastitis in a milk producing animal. The methods include administering compositions including siderophore receptor polypeptides and porins from gram negative microbes, and preferably, lipopolysaccarhide at a concen...
03/11/2008
7160549Methods for making compositions including gram negative microbial polypeptides
The present invention provides methods for making compositions including siderophore receptor polypeptides and porins from gram negative microbes. The methods include providing a gram negative microbe, disrupting the microbe, solubilizing the disrupted microbe, and ...
01/09/2007
7125696Method for preparing a polypeptide soluble in an aqueous solvent in the absence of detergent
A invention concerns a novel method for preparing a polypeptide soluble in an aqueous solvent in the absence of detergent, and polypeptides obtainable by said method. The invention also concerns the use of said polypeptides, in particular for preparing medicines or ...
10/24/2006
7090853Noscapine derivatives as adjuvant compositions and methods of use thereof
An adjuvant composition comprising noscapine and its derivatives, for use in the treatment of tumors, cancer, as an adjuvant for vaccines. ...
08/15/2006
7033591Immunostimulant bacterial membrane fractions in cancer treatment
The invention concerns the use of a membrane fraction of gram-negative bacteria, in particular Klebsiella pnemoniae for preparing a pharmaceutical composition that is immunostimulant and/or capable of inducing an antitumoral immune response, designed in parti...
04/25/2006
7018636Vaccine against Gram-negative bacterial infections
A vaccine, effective in inducing the production of antibodies with which to immunize a second subject passively against infection by Gram-negative bacteria and LPS-mediated pathology, comprises a non-covalent polyvalent complex formed between purified, detoxified LP...
03/28/2006
6913753Incapacitated whole-cell immunogenic bacterial compositions
The invention features incapacitated whole cell bacterial immunogenic compositions produced by infecting a bacterium with Lys minus bacteriophage, which are deficient in the lysin protein. Lys minus bacteriophage retain activity in infection of its appropriate bacte...
07/05/2005
6905691Vaccines containing attenuated bacteria
The invention relates to a vaccine comprising a bacterium attenuated by a non-reverting mutation in a gene encoding a protein which promotes folding of extracytoplasmic proteins. Such mutations were initially identified as being useful in vaccines from a bank of ran...
06/14/2005
6780420Carrier protein having an adjuvant effect, immunogenic complex containing it, process for their preparation, nucleotide sequence and vaccine
The invention relates to an adjuvant product which is intended to improve the activity of a molecule when administered to a host, characterized in that it comprises at least one part of the P40 protein of Klebsiella pneumoniae or a protein having at least 80%...
08/24/2004
6632431Anti-idiotypic antibody against FimH adhesion of uropathogenic type I-fimbriated Escherichia coli, compositions containing same and method for using same
The present invention relates to an anti-idiotypic antibody or antigen-binding fragment against FimH adhesin of uropathogenic Type I-fimbriated Escherichia coli and an immunizing composition containing such an anti-idiotypic antibody or antigen-binding fr...
10/14/2003
6423320Inhibitor of immunoglobulin E antibody production
A polysaccharide and fragments thereof derived from Klebsiella oxytoca or Klebsiella pneumonia inhibit the IgE antibody production and response and, therefore, are useful in the prophylaxis and/or treatment of type I allergy-related diseases....
07/23/2002
6197929Carrier protein having an adjuvant effect, immunogenic complex containing it, process for their preparation, nucleotide sequence and vaccine
The invention relates to an adjuvant product which is intended to improve the activity of a molecule when administered to a host, characterized in that it comprises at least one part of the P40 protein of Klebsiella pneumoniae or a protein having at least...
03/06/2001
6083928Skin healing method
A method for facilitating the healing of skin comprising applying topically to skin a composition containing an amount of a lipopolysaccharide extracted from gram negative bacteria effective to facilitate skin healing....
07/04/2000
6045805Oligosaccharide derived from an antigenic polysaccharide obtained from a pathogenic agent
An oligosaccharide derived from an antigen polysaccharide obtained from a pathogenic agent, a method for its preparation, and its use particularly as a vaccinal agent. The oligosaccharide is prepared by oxidation-reduction depolymerization reaction....
04/04/2000
6027736Active immunization using a siderophore receptor protein
The invention provides a vaccine for immunizing poultry and other animals against infection by a gram-negative bacteria, and a method of immunizing an animal using the vaccine. The vaccine may contain purified siderophore receptor proteins derived from a ...
02/22/2000
6007818Oligosaccharide derived from an antigenic polysaccharide obtained from a pathogenic agent
An oligoside derived from an antigen polyoside obtained from a pathogenic agent, a method for its preparation, and its use particularly as a vaccinal agent. The oligoside is prepared by oxidation-reduction depolymerisation reaction....
12/28/1999
5997881Method of making non-pyrogenic lipopolysaccharide or A
The present invention provides gram-negative bacterial strains that produce substantially pure non-pyrogenic lipopolysaccharide or lipid A. The present invention also relates to a use of said strains for the preparation of non-pyrogenic DNA and use of the...
12/07/1999
5906826Method of inducing an immune response in a young animal
The invention provides a method of priming an immune response in the presence of maternal antibody in a young animal by administering to a 1-90 day old animal, a biocompatible and non-toxic solid phase implant containing an immunogenic agent. A preferred ...
05/25/1999
5538727Anti-cholesterolemic vaccine
Anti-cholesterolemic eggs are disclosed, said eggs being obtained from animals hyperimmunized against at least one anti-cholesterolemic antigen. A vaccine producing said anti-cholesterolemic egg is disclosed, said vaccine comprising at least one anti-chol...
07/23/1996
5538733Method of priming an immune response in a one-day old animal
The invention provides a method of priming an immune response in the presence of maternal antibody in a young animal by administering to a 1-90 day old animal, a biocompatible and non-toxic solid phase implant containing an immunogenic agent. A preferred ...
07/23/1996
4764370Vaccine utilizing an avirulent strain of Salmonella typhimurium
A vaccine against a microbial pathogen comprised of a live, immunogenic but prototrophic and avirulent mutant strain of the selected microbial pathogen in an amount effective to confer immunity. A method of obtaining a vaccine that induces a heightened ce...
08/16/1988
4755381Klebsiella capsular polysaccharide vaccine
The present invention relates to immunogenic preparations of Klebsiella species serotype-specific capsular polysaccharides. The invention involves the treatment of Klebsiella capsular polysaccharides in dilute sodium hydroxide to detoxify co-purified toxi...
07/05/1988
4663160Vaccines for gram-negative bacteria
An immunizing composition is disclosed and comprises a detoxified polysaccharide from a gram-negative bacterium covalently coupled to a detoxified protein from said gram-negative bacterium by means of a 4-12 carbon moiety. To prepare the above immunizing ...
05/05/1987
4606919Vaccine for the treatment of urinary tract infections containing aluminum phosphate
A vaccine for curative and prophylactic treatment of urinary tract infections in humans. The vaccine contains inactivated bacteria which originate from the cultures of 8 to 14 uropathogenic bacteria strains isolated from the urine of a person suffering fr...
08/19/1986
4460575Vaccinal complex containing a specific antigen and vaccine containing it
The present invention relates to a vaccinal complex containing a specific antigen. This is a vaccinal complex characterized in that it is composed of bacterial ribosomal RNA or fragments of bacterial ribosomal RNA on which are coupled from 1 to 5% by weig...
07/17/1984
4402939Vaccinating glycopeptidic antigenic fraction with a very high level of immunogenicity, isolated from cultures of pathogenic germs, processes for isolating said fraction and vaccines containing said fraction
A glycopeptic vaccinating antigenic fraction with a very high level of immunogenicity, which is isolated from a culture of pathogenic germs comprises an osidic part present in a proportion of about 50%, with a proteinic part, which are linked together by ...
09/06/1983
4396607Muramyl peptide derivatives and pharmaceutical compositions
The invention relates to new compounds useful notably as regulator of immune responses and which are derivatives of muramyl peptides substituted at the end of the peptide chain by a group containing at least four carbon atoms....
08/02/1983
4356171Novel glycoproteins
Novel water-soluble, immunostimulating glycoproteins extracted from Klebsiella Pneumoniae containing 20 to 35% by weight of proteins, 50 to 70% by weight of neutral monosaccharides, 3 to 8% by weight of glucuronic acid, 1.5 to 3% by weight of osamines and...
10/26/1982
4349540Process for preparing vaccines based on antigenic ribosomal fractions
Vaccines which comprise in association the ribosomal fraction extracted from the bacterias against which a protection is wanted, and the peptidoglycanes extracted from the membranes of at least one of the bacteria previously used....
09/14/1982
 
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