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| Number | Title | Issue Date |
| 8084043 | Subunit vaccine of in veterinary uses The present invention declaims the use of Pasteurella lipoprotein E (PlpE) as a subunit vaccine and the use of vaccines containing PlpE to protect animals from diseases caused by P. multocida. The results of vaccination and challenge experiments showed... | 12/27/2011 |
| 7794735 | Pathogen for bacterial poultry disease The invention belongs to the field of animal health and in particular the causative agent of a new bacterial poultry disease, Gallibacterium. The invention provides said Gallibacterium bacteria, vaccine comprising inactivated Gallibacterium, and... | 09/14/2010 |
| 7794734 | chimeric outer membrane protein PlpE and leukotoxin epitopes as a vaccine or vaccine component against shipping fever Vaccine preparations for the prevention and treatment of bovine respiratory disease (BRD) and, in particular, its most severe form, termed “shipping fever”, are provided. The preparations comprise chimeric proteins comprising immunodominant epitopes of recombina... | 09/14/2010 |
| 7763262 | Attenuated yiaO mutants of bacteria Gram negative bacterial virulence genes are identified, thereby allowing the identification of novel anti-bacterial agents that target these virulence genes and their products, and the provision of novel gram negative bacterial mutants useful in vaccines. ... | 07/27/2010 |
| 7521060 | Pathogen for bacterial poultry disease The invention belongs to the field of animal health and in particular the causative agent of a new bacterial poultry disease, Gallibacterium. The invention provides said Gallibacterium bacteria, vaccine comprising inactivated Gallibacterium, and... | 04/21/2009 |
| 7476391 | Anti-bacterial vaccine compositions Gram negative bacterial virulence genes are identified, thereby allowing the identification of novel anti-bacterial agents that target these virulence genes and their products, and the provision of novel gram negative bacterial mutants useful in vaccines. ... | 01/13/2009 |
| 7413743 | Active immunization using a siderophore receptor protein The invention provides a vaccine for immunizing poultry and other animals against infection by a gram-negative bacteria, and a method of immunizing an animal using the vaccine. The vaccine may contain purified siderophore receptor proteins derived from a single stra... | 08/19/2008 |
| 7371393 | Methods for reducing fecal shedding The present invention provides methods for reducing shedding in an animal. Generally, the method includes administcriirn to an animal a composition including siderophore receptor polypeptides and porins from gram negative microbes, and preferably, lipopolysaccarhide... | 05/13/2008 |
| 7351416 | Vaccines comprising acapsular deletion mutants Acapsular hyaE deletion mutants of P. multocida can be administered to mammals, particularly ungulates, or birds to provide protective immunity against wild-type P. multocida, e.g., to prevent or reduce the severity of hemorrhagic septicemia or pneumon... | 04/01/2008 |
| 7341732 | Methods for treating mastitis in a milk producing animal The present invention provides methods for treating mastitis in a milk producing animal. The methods include administering compositions including siderophore receptor polypeptides and porins from gram negative microbes, and preferably, lipopolysaccarhide at a concen... | 03/11/2008 |
| 7333156 | Sequential colour visual telepresence system For implementing an anthropomorphic visual telepresence system with high resolution and low loop latency a sequential color video loop is provided. A sequential color camera sequentially captures color images, each captured image consisting of a portion of a single ... | 02/19/2008 |
| 7220421 | cytotoxin, cytotoxin gene, antibodies and vaccines for prevention and treatment of infections Moraxella bovis cytotoxin and a gene encoding Moraxella bovis cytotoxin. Identification, isolation, cloning and identification of nucleotide sequence of the Moraxella bovis genes mbxA, mbxB, mbxC and mbxD, partial purification of the native cyto... | 05/22/2007 |
| 7217541 | Method of making CS6 antigen vaccine for treating, preventing, or inhibiting enterotoxigenic infections Disclosed herein are methods for making large amounts of highly pure colonization factors. The methods of the present invention differ from prior art methods in that host cells which express the colonization factor of interest are cultured in media comprising more t... | 05/15/2007 |
| 7202031 | Detection of microsatellite instability and its use in diagnosis of tumors Methods and kits are disclosed for use in the analysis of microsatellite instability in genomic DNA. Methods and kits are also disclosed which can be used to detect microsatellite instability DNA present in biological materials, such as tumors. The methods and kits ... | 04/10/2007 |
| RE39494 | Inactivated mycoplasma hyopneumoniae and uses therefor The invention relates to a method for making an inactivated vaccine of Mycoplasma hyopneumoniae by inactivating the bacteria with Thimerosal. The resulting bacterin is mixed with an adjuvant of aluminum hydroxide and DEAE dextran and injected into pigs. The r... | 02/27/2007 |
| 7172762 | antigens and vaccine compositions The invention relates to stabilized antigen compositions of Erysipelothrix rhusiopathiae and vaccine formulations containing such antigen compositions. Antigens of the invention are effective in providing long-term protection against erysipelas in animals. | 02/06/2007 |
| 7160549 | Methods for making compositions including gram negative microbial polypeptides The present invention provides methods for making compositions including siderophore receptor polypeptides and porins from gram negative microbes. The methods include providing a gram negative microbe, disrupting the microbe, solubilizing the disrupted microbe, and ... | 01/09/2007 |
| 7144580 | outer membrane protein P1pE as a vaccine or vaccine component against shipping fever Vaccines and methods against M. haemolytica infections in cattle. The vaccine compositions include a recombinant outer membrane protein of M. haemolytica designated PlpE and/or subunits thereof, alone or in combination with other antigenic components, ... | 12/05/2006 |
| 7138124 | Polypeptides obtained from gram negative microbes The present invention provides compositions including at least two siderophore receptor polypeptides and at least two porins from a gram negative microbe, and preferably, lipopolysaccharide at a concentration of no greater than about 10.0 endotoxin units per millili... | 11/21/2006 |
| 7114608 | Directional transition module for use in conjunction with a roller-type conveyor A directional transition module for moving an article translating on a primary roller conveyor extending along a first axis to a secondary conveyor for translation along a second axis angularly disposed with respect to the first axis includes at least one flexible d... | 10/03/2006 |
| 7018639 | Vaccine antigens of The present invention relates to antigens of Moraxella, in particular, Moraxella bovis, nucleic acid sequences encoding these antigens and formulations for use in raising an immune response against Moraxella. ... | 03/28/2006 |
| 7011957 | Isolation and cultivation of microorganisms from natural environments and drug discovery based thereon The method of the invention is directed to the novel use of a diffusion chamber within which previously “uncultivatible” microorganisms can be isolated. Rather than attempting to replicate the natural environment of an unknown microorganism, the method of the in... | 03/14/2006 |
| 6936262 | LktA deletion mutant of P. haemolytica Mutants of P. haemolytica provide excellent safety and efficacy when used as vaccines in ruminants, for example cattle, sheep, and goats, subject to pneumonic pasteurellosis. They can be administered by a variety of routes. Especially preferred is the use in ... | 08/30/2005 |
| 6814971 | Adjuvants for use in vaccines The invention relates to adjuvants that contain a lecithin, an oil and an amphiphilic surfactant and that are capable of forming a stable oil-in-water emulsion vaccine so as to minimize local reactions to the vaccine in the injected animal. ... | 11/09/2004 |
| 6797272 | Enhanced immunogenicity using leukotoxin chimeras New immunological carrier systems, DNA encoding the same, and the use of these systems, are disclosed. The carrier systems include chimeric proteins which comprise a leukotoxin polypeptide fused to a selected antigen. The leukotoxin functions to increase the immunog... | 09/28/2004 |
| 6793927 | Construction of Pasteurella haemolytica vaccines Methylation of DNA can be a critical step in the introduction of DNA into P. haemolytica. A methyltransferase has been isolated and molecularly cloned for this purpose. Use of the methyltransferase has allowed construction of defined, attenuated mutants for u... | 09/21/2004 |
| 6743430 | Multicomponent vaccine containing clostridial and non-clostridial organisms in a low dose Disclosed herein is a multicomponent low dose vaccine comprising a safe and immunogenically effective combination of a protective antigen component or components of clostridial organism, a protective antigen component of a non-clostridial organism and an adjuvant. | 06/01/2004 |
| 6733754 | Adjuvants for use in vaccines The invention relates to adjuvants that contain a lecithin, an oil and an amphiphilic surfactant and that are capable of forming a stable oil-in-water emulsion vaccine so as to minimize local reactions to the vaccine in the injected animal. ... | 05/11/2004 |
| 6610506 | Transferrin binding proteins of Pasteurella haemolytica and vaccines containing same Novel transferrin binding proteins from Pasteurella haemolytica, and nucleic acid molecules encoding the novel proteins are disclosed. Antibodies against the novel proteins are disclosed. The invention also relates to vaccines containing the novel protein... | 08/26/2003 |
| 6610307 | Immunity against pasteurella haemolytica leukotoxin Bovine respiratory disease (BRD) complex, shipping fever, or pneumomic pasteurellosis, is a multifactorial disease whereby a combination of viral infection, adverse environment and poor immune status may combine to predispose animals to bacterial infectio... | 08/26/2003 |
| 6585981 | Temperature-sensitive live vaccine for Mycoplasma hyopneumoniae The present invention provides a live temperature-sensitive vaccine for Mycoplasma hyopneumoniae. The present invention also provides methods of vaccinating a swine against colonization or infection of Mycoplasma hyopneumoniae.... | 07/01/2003 |
| 6572861 | Adjuvants for use in vaccines The invention relates to adjuvants that contain a lecithin, an oil and an amphiphilic surfactant and that are capable of forming a stable oil-in-water emulsion vaccine so as to minimize local reactions to the vaccine in the injected animal.... | 06/03/2003 |
| 6573093 | Temperature sensitive plasmids of P. haemolytica Mutants of P. haemolytica provide excellent safety and efficacy when used as vaccines in ruminants, for example cattle, sheep, and goats, subject to pneumonic pasteurellosis. They can be administered by a variety of routes. Especially preferred is the use... | 06/03/2003 |
| 6495145 | LktA deletion mutant of P. haemolytica Mutants of P. haemolytica provide excellent safety and efficacy when used as vaccines in ruminants, for example cattle, sheep, and goats, subject to pneumonic pasteurellosis. They can be administered by a variety of routes. Especially preferred is the use... | 12/17/2002 |
| 6410021 | Vaccines of pasteurellaceae mutants and vaccination method A live vaccine of recombinant mutants of a member of the family Pasteurellaceae lacking a rib gene necessary for production of riboflavin as well as a method of vaccination therewith is described. The vaccine is effective against members of the family Pas... | 06/25/2002 |
| 6350454 | Attenuated Pasteurella piscicida vaccine for fish Live-attenuated vaccines against Edwardsiella ictaluri or against Pasteurella piscicida are disclosed. Both vaccines are incapable of reversion to virulence, because both are made by deletion mutations in the aroA gene, the purA gene, or both. These vacci... | 02/26/2002 |
| 6331303 | LKTA deletion mutant of P. haemolytica Mutants of P. haemolytica provide excellent safety and efficacy when used as vaccines in ruminants, for example cattle, sheep, and goats, subject to pneumonic pasteurellosis. They can be administered by a variety of routes. Especially preferred is the use... | 12/18/2001 |
| 6303130 | Pasteurella haemolytica vaccine inactivated by ultraviolet light A novel vaccine for immunizing animals against Pasteurella haemolytica infection is disclosed. The vaccine is composed of whole killed cells of P. haemolytica in a dosage effective to immunize an animal against the organism, in combination with a pharmace... | 10/16/2001 |
| 6180112 | Pasteurella haemolytica vaccine The present invention is directed to compositions and methods for the production for the prevention of disease due to P. haemolytica. In particular, the present invention provides P. haemolytica strains that produce inactive leukotoxin for vaccine and oth... | 01/30/2001 |
| 6110470 | Pasteurella multocida toxin derivatives A vaccine for immunizing animals against diseases caused by microorganisms producing an osteolytic toxin comprising an immunologically effective amount of a recombinant, immunogenic, detoxified Pasteurella multocida toxin or toxin analog, the vaccine bein... | 08/29/2000 |
