Bizarre Patents
An enclosure for small animals which is wearable on the front or back of an animate being.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 8163295 | Outer membrane vesicles and uses thereof The present invention discloses a Gram negative bacterium in which the expression of a protein involved in LPS transport to the outer membrane is functionally down-regulated such that the level of LPS in the outer membrane is decreased compared to a wild-type Gram n... | 04/24/2012 |
| 8029807 | Outer membrane vesicles and uses thereof The present invention discloses a Gram negative bacterium in which the expression of a protein involved in LPS transport to the outer membrane is functionally downregulated such that the level of LPS in the outer membrane is decreased compared to a wild-type Gram ne... | 10/04/2011 |
| 7871628 | Peptide mimics of conserved gonococcal epitopes and methods and compositions using them The present invention relates to peptide mimics of a conserved gonococcal epitope of Neisseria gonorrhoeae, which epitope is not found on human blood group antigens. This invention also relates to methods and compositions using such peptide mimics for the pro... | 01/18/2011 |
| 7838014 | Vaccine compositions comprising L2 and/or L3 immunotype lipooligosaccharides from LGTB- The present invention relates to the field of neisserial vaccine compositions, their manufacture, and the use of such compositions in medicine. More particularly it relates to processes of making novel engineered meningococcal strains which are more suitable for the... | 11/23/2010 |
| 7820185 | Stable compositions containing OMVs An OMV preparation comprises OMVs having a sufficiently positive or negative surface charge to substantially prevent aggregation. ... | 10/26/2010 |
| 7807183 | Transport agents for crossing the blood-brain barrier and into brain cancer cells, and methods of use thereof The present invention discloses methods and materials for delivering a cargo compound into a brain cancer cell and/or across the blood-brain barrier. Delivery of the cargo compound is accomplished by the use of protein transport peptides derived from Neisseria | 10/05/2010 |
| 7785608 | Immunogenic compositions for the prevention and treatment of meningococcal disease The present invention relates to Neisseria ORF2086 proteins, crossreactive immunogenic proteins which can be isolated from nesserial strains or prepared recombinantly, including immunogenic portions thereof, biological equivalents thereof, antibodies that imm... | 08/31/2010 |
| 7776342 | Preparations that potentiate immunogenicity in low immunogenic antigens This invention discloses means for obtaining immunogenic peptides, polypeptides, proteins, and their corresponding nucleic acid sequences, target cells with vaccine interest, or lysates thereof, without making structural changes in said antigens, through their assoc... | 08/17/2010 |
| 7648709 | Allergy vaccine composition, production method thereof and use of same in allergy treatment The present invention relates to the field of Immunology, specifically with the branch of Immuno-Allergy and in particular with the use of adjuvant or carrier compounds, capable of modulating the immune response to allergens. The technical objective that is pursued ... | 01/19/2010 |
| 7628995 | Outer membrane vesicles and uses thereof The present invention discloses a Gram negative bacterium in which the expression of a protein involved in LPS transport to the outer membrane is functionally downregulated such that the level of LPS in the outer membrane is decreased compared to a wild-type Gram ne... | 12/08/2009 |
| 7504111 | Gonococcal proteins and nucleic acids The invention provides proteins from gonococcus (Neisseria gonorrhoeae), including amino acid sequences, the corresponding nucleotide sequences, expression data, and serological data. The proteins are useful antigens for vaccines, immunogenic compositions, an... | 03/17/2009 |
| 7422754 | compounds and anti-infection applications thereof The invention provides novel Neisseria meningitides (Nm) polypeptides and polynucleotides which cover the Nm genetic diversity, and which correspond to polypeptide of Nm outer membrane and/or periplasma, and to methods for producing such Nm compounds. Also pr... | 09/09/2008 |
| 7399840 | Proteosome influenza vaccine Improved forms of vaccines which comprise proteosomes and protein antigens are described. Vaccines which contain influenza HA as the antigen are used for illustration as to demonstrate efficacy. Improvements in the preparation of the vaccines themselves and the prot... | 07/15/2008 |
| 7384645 | Outer membrane vesicles from gram negative bacteria and use as a vaccine A composition is prepared from a mixture of different vesicles, such as outer membrane vesicles (OMVs) and vaccines are based thereon. Another composition comprises in a single vesicle a combination of antigens and/or other vesicle components deriving from separate ... | 06/10/2008 |
| 7357932 | Surface protein of bacteria Present invention provides a monoclonal antibody binding to Neisseria bacteria and its target antigen Ag473, which include the sequences of its polynucleotide and its amino acid, wherein the Neisseria bacteria can be Neisseria meningitidis or | 04/15/2008 |
| 7273611 | Proteinase K resistant surface protein of neisseria meningitidis The identification of a highly conserved, immunologically accessible antigen on the surface of Neisseria facilitates treatment, prophylaxis, and diagnosis of Neisseria diseases. This antigen is highly resistant to proteinase K and has an apparent molec... | 09/25/2007 |
| 7261901 | Vaccine and compositions for the prevention and treatment of neisserial infections The present invention is directed to novel polypeptides, polynucleotides and vaccines for use against Neisseria gonorrhoeae colonization or infection and/or Neisseria meningitidis colonization or infection. The vaccines contain an immunogenic amount of... | 08/28/2007 |
| 7250172 | Vaccine and compositions for the prevention and treatment of neisserial infections The present invention is directed to novel polypeptides, polynucleotides and vaccines for use against Neisseria gonorrhoeae colonization or infection. The vaccines contain an immunogenic amount of a neisserial protein. ... | 07/31/2007 |
| 7235242 | IgA1 protease fragment as carrier peptides The present invention is concerned with a fragment of IgA1-protease having 40 to 200 amino acid residues and comprising at least 40 amino acids of an amino acid sequence as shown in SEQ ID NO:1, beginning with the amino acid in any one of positions 1 to 5 and ending... | 06/26/2007 |
| 7189405 | Peptide mimics of conserved gonococcal epitopes and methods and compositions using them The present invention relates to peptide mimics of a conserved gonococcal epitope of Neisseria gonorrhoeae, which epitope is not found on human blood group antigens. This invention also relates to methods and compositions using such peptide mimics for the pro... | 03/13/2007 |
| 7157245 | Neisserial vaccine compositions and methods Methods and compositions for the treatment of microbial infection, and in particular meningococcal disease, comprise a commensal Neisseria or an extract of a commensal Neisseria. Further methods and compositions comprise commensal Neisseria whic... | 01/02/2007 |
| 7112332 | Oral or intranasal vaccines using hydrophobic complexes having proteosomes and lipopolysaccharides An immunogenic complex, essentially consisting of neisserial outer membrane protein proteosomes hydrophobically complexed to native purified bacterial lipopolysaccaride and formulated in accordance with the current invention for mucosal delivery such as via the oral... | 09/26/2006 |
| 7081244 | Neisserial vaccine compositions and methods Methods and compositions for the treatment of microbial infection, and in particular meningococcal disease, comprise a commensal Neisseria or an extract of a commensal Neisseria. Further methods and compositions comprise conimensal Neisseria whi... | 07/25/2006 |
| 7070781 | Nontoxic mucosal adjuvant A non-toxic mucosal adjuvant is provided which may be admixed with further antigens to provide a vaccine administrable to mucosal surfaces in organisms including man. Preferably, the non-toxic mucosal adjuvant is a detoxified mutant of a bacterial ADP-ribosylating t... | 07/04/2006 |
| 7029678 | Vaccines The present invention provides vaccine compositions comprising an oil-in-water emulsion optionally with 3 De-O-acylated monophosphoryl lipid A and QS21. The vaccine compositions are potent induces of a range of immune responses. ... | 04/18/2006 |
| 7018637 | Multi-oligosaccharide glycoconjugate bacterial meningitis vaccines Multivalent immunogenic molecules comprise a carrier molecule containing at least one functional T-cell epitope and multiple different carbohydrate fragments each linker to the carrier molecule and each containing at least one functional B-cell epitope. The carrier ... | 03/28/2006 |
| 6994860 | antigenic polypeptides, corresponding polynucleotides and protective antibodies The invention provides Neisseria meningitidis BASB030 polypeptides and polynucleotides encoding BASB030 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are antibodies, diagnostic, prophylactic and therapeutic ... | 02/07/2006 |
| 6936261 | Vaccines for broad spectrum protection against diseases caused by Neisseria meningitidis The present invention generally provides methods and vaccines for the prevention of diseases caused by Neisseria meningitidis bacteria, particularly serogroup B strains. ... | 08/30/2005 |
| 6913753 | Incapacitated whole-cell immunogenic bacterial compositions The invention features incapacitated whole cell bacterial immunogenic compositions produced by infecting a bacterium with Lys minus bacteriophage, which are deficient in the lysin protein. Lys minus bacteriophage retain activity in infection of its appropriate bacte... | 07/05/2005 |
| 6887482 | Antigenic iron repressible proteins from N. meningitidis related to the hemolysin family of toxins An isolated, antigenic polypeptide comprises a segment having at least fifty amino acid residues. The amino acid sequence of the segment is present in N. meningitidis, and is different from, but substantially homologous with, the amino acid sequence of a segm... | 05/03/2005 |
| 6835384 | Nucleic acids and polypeptides specific of the neisseria genus pathogenic strains The invention concerns nucleic acids coding for polypeptides specific of the Neisseria genus pathogenic strains, the corresponding polypeptides, and their diagnostic and therapeutic applications. ... | 12/28/2004 |
| 6821521 | Multicomponent meningococcal vaccine A composition comprising Transferrin binding proteins A and B is described (TbpA and TbpB). The composition is suitable for use in vaccines and for treatment of Gram negative bacterial infection, particularly meningococcal infection, demonstrating a broad spectrum o... | 11/23/2004 |
| 6803042 | Oral or intranasal vaccines using hydrophobic complexes having proteosomes and lipopolysaccharides An immunogenic complex, essentially consisting of neisserial outer membrane protein proteosomes hydrophobically complexed to native purified bacterial lipopolysaccharide and formulated in accordance with the current invention for mucosal delivery such as via the ora... | 10/12/2004 |
| 6797274 | Compounds The invention provides BASB047, BASB054, BASB068 and BASB069 polypeptides, and polynucleotides encoding BASBO47, BASB054, BASB068 and BASB069 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic, prophylact... | 09/28/2004 |
| 6797273 | Neisseria meningitidis antigen The invention provides BASB053 polypeptides and polynucleotides encoding BASB053 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic, prophylactic and therapeutic uses. ... | 09/28/2004 |
| 6770284 | Polypeptides and polynucleotides BASB040 from neisseria meningitidis and vaccine comprising said polypeptides and polynucleotides The invention provides BASB040 polypeptides and polynticleotides from Neisseria meningitidis encoding BASB040 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic, prophylactic and therapeutic uses. | 08/03/2004 |
| 6756493 | Nucleic acid sequence and uses thereof The invention discloses the Neisseria spp. NGSP polypeptide, polypeptides derived therefrom (NGSP-derived polypeptides), nucleotide sequences encoding said polypeptides, and antibodies that specifically bind the NGSP polypeptide and/or NGSP-derived polypeptides. Als... | 06/29/2004 |
| 6743607 | Production of complex carbohydrates Compositions and methods for making complex carbohydrates in a bacterial production cell are disclosed. The complex carbohydrates that can be made include oligosaccharides and polysaccharides of bacterial or mammalian origin. ... | 06/01/2004 |
| 6743900 | Proteosome influenza vaccine Improved forms of vaccines which comprise proteosomes and protein antigens are described. Vaccines which contain influenza HA as the antigen are used for illustration as to demonstrate efficacy. Improvements in the preparation of the vaccines themselves and the prot... | 06/01/2004 |
| 6709660 | Meningococcal antigens The invention provides proteins from Neisseria meningitidis (strains A & B), including amino acid sequences, the corresponding nucleotide sequences, expression data, and serological data. The proteins are useful antigens for vaccines, immunogenic compositions... | 03/23/2004 |
