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| Number | Title | Issue Date |
| 8183220 | Double-effective vaccine vector against foot-and-mouth disease virus (FMDV), methods of preparing and using the same A double-effective vaccine vector against foot-and-mouth disease virus having a bicistronic expression vector sequence, the bicistronic expression vector sequence is an antisense gene sequence capable of conjugating with 5′ UTR of RNA of the foot-and-mouth disease... | 05/22/2012 |
| 8142793 | Norovirus and Sapovirus antigens Immunogenic compositions that elicit immune responses against Norovirus and Sapovirus antigens are described. In particular, the invention relates to polynucleotides encoding one or more capsid proteins or other immunogenic viral polypeptides from one or more strain... | 03/27/2012 |
| 8124104 | Norovirus and sapovirus antigens Immunogenic compositions that elicit immune responses against Norovirus and Sapovirus antigens are described. In particular, the invention relates to polynucleotides encoding one or more capsid proteins or other immunogenic viral polypeptides from one or more strain... | 02/28/2012 |
| 8119145 | Methods for producing norovirus VLPS Immunogenic compositions that elicit immune responses against Norovirus and Sapovirus antigens are described. In particular, the invention relates to polynucleotides encoding one or more capsid proteins or other immunogenic viral polypeptides from one or more strain... | 02/21/2012 |
| 8114416 | Modified oncolytic viruses An isolated selected Picornavirus capable of lytically infecting or killing a cell substantially in the absence of intercellular adhesion molecule-1 (ICAM-1). ... | 02/14/2012 |
| 8101189 | Vaccines and immunopotentiating compositions and methods for making and using them An immunopotentiating composition comprising a papaya mosaic virus (PapMV), or a virus-like particle (VLP) derived from PapMV coat protein, which is capable of functioning as an adjuvant and thus potentiating an immune response in an animal is provided. The immunopo... | 01/24/2012 |
| 7879338 | Vectors and methods for immunization against norovirus using transgenic plants The present invention relates to a synthetic plant-optimized nucleic acid molecule having a Norwalk virus capsid protein coding nucleotide sequence, and nucleic acid constructs, host cells, expression systems, and plants having the plant-optimized Norwalk virus nucl... | 02/01/2011 |
| 7850978 | Vaccine against feline calicivirus The present invention relates to improved methods and immunogenic and/or vaccine compositions for providing an immune response to feline calicivirus, including hypervirulent strains of feline calicivirus. ... | 12/14/2010 |
| 7833533 | Enhanced antiviral activity against foot and mouth disease Previously, we showed that type I interferon (alpha/beta interferon [IFN-α/β]) can inhibit foot-and-mouth disease virus (FMDV) replication in cell culture, and swine inoculated with 109 PFU of human adenovirus type 5 expressing porcine IFN-α (Ad5-pIFN-... | 11/16/2010 |
| 7763260 | Murine calicivirus The invention disclosed herein relates to a newly discovered murine norovirus, and compositions and methods related thereto. ... | 07/27/2010 |
| 7611719 | Enterovirus, vaccines, medicaments and diagnostic kits The invention provides a new enteroviral species call EV79, and functional parts, derivatives and analogues of said virus. Proteinaceous molecules capable of specifically binding EV79, such as isolated or recombinant antibodies, are also herewith provided. A virus a... | 11/03/2009 |
| 7575753 | SRSV detection kit This invention relates to an SRSV detection kit comprising all antibodies against SRSV-related virus constituting peptides selected from the following peptide groups (a) to (k), respectively: (a) a peptide having an amino acid sequence represented by SEQ ID NO: 1, a... | 08/18/2009 |
| 7531182 | Vaccine against foot-and-mouth disease A vaccine against foot-and-mouth disease, using as antigen an efficient amount of empty capsids of the foot-and-mouth virus. The empty capsids are obtained by expressing, in eukaryotic cells, cDNA of the P1 region of the foot-and-mouth virus genome coding for the ca... | 05/12/2009 |
| 7527801 | Norovirus and Sapovirus antigens Immunogenic compositions that elicit immune responses against Norovirus and Sapovirus antigens are described. In particular, the invention relates to polynucleotides encoding one or more capsid proteins or other immunogenic viral polypeptides from one or more strain... | 05/05/2009 |
| 7442380 | Treatment of diseases caused by viral infection A method of prophylactic and/or therapeutic treatment of a mammal for a disease that is caused by a Ljungan virus infection, such as Myocarditis, Cardiomyopathia, Guillain Barré Syndrome, and Diabetes Mellitus, Multiple Sclerosis, Chronic Fatigue Syndrome, Myasthen... | 10/28/2008 |
| 7309495 | Hemorrhagic feline calicivirus The present invention relates to a vaccine for immunization against a viral infection caused by a hemorrhagic feline calicivirus (hFCV), a novel, a typical and unusually virulent form of a calicivirus that results in a highly contagious and fatal hemorrhagic fever s... | 12/18/2007 |
| 7306807 | Hemorrhagic feline calicivirus, calicivirus vaccine and method for preventing calicivirus infection or disease The present invention relates to a novel, isolated and purified hemorrhagic feline calicivirus FCV-DD1. The invention further embraces monovalent and multivalent vaccines containing the new FCV-DD1 strain. In addition, the invention encompasses methods of protecting... | 12/11/2007 |
| 7264816 | Virulent systemic feline calicivirus The present invention relates to a vaccine for immunization against a viral infection caused by a virulent systemic feline calicivirus (VS-FCV), a novel, atypical and unusually virulent form of a calicivirus that results in a highly contagious and fatal hemorrhagic ... | 09/04/2007 |
| 7264802 | Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV) The present invention provides a purified preparation containing, for example, at least one polypeptide selected from the group consisting of proteins encoded by one or more open reading frames (ORF's) of an Iowa strain of porcine reproductive and respiratory syndro... | 09/04/2007 |
| 7247457 | Detection and identification of enteroviruses by semi-nested amplification of the enterovirus VP1 protein Disclosed are methods of using enterovirus-specific primers for the detection and identification of enterovirus infection. Also provided are isolated nucleic acid molecules and kits useful for detection and diagnostic testing of enterovirus infection in a subject. | 07/24/2007 |
| 7189401 | Live attenuated viruses for use as vectors or vaccines The present invention provides modified viral genomes for use as vaccines or vectors, which are improved in their ability to retain attenuating mutations. The genomes are from viruses that replicate by way of an RNA-dependent RNA or DNA polymerase. The genomes are m... | 03/13/2007 |
| 7122193 | Retro peptides, antibodies thereto and their uses for vaccination and in vitro diagnosis The present invention relates to retro peptides, as well as antibodies thereto, and to their uses, chiefly in the field of preparation of pharmaceutical compositions, in particular vaccines, and for in vitro diagnosis of various pathologies. ... | 10/17/2006 |
| 7101554 | Picornaviruses, vaccines and diagnostic kits A new group of picornaviruses is disclosed. The picornaviruses of the invention comprise in the non-coding region of their viral genome a nucleotide sequence which corresponds to cDNA sequence (I) or homologous sequences having at least 75% homology to the SEQ ID NO... | 09/05/2006 |
| 7090855 | Prevention of Type 1 diabetes and other non-polio enterovirus diseases Live virus vaccines comprise attenuated viruses, while other vaccines comprise killed viruses or parts thereof. It has now been found that the immune response induced by oral poliovirus vaccine (OPV), which is a live vaccine, is cross-reactive with non-polio enterov... | 08/15/2006 |
| 7041444 | Murine calicivirus The invention disclosed herein relates to a newly discovered murine norovirus, and compositions and methods related thereto. ... | 05/09/2006 |
| 7037506 | Vaccine accelerator factor (VAF) for improvement of vaccinations in poultry The present invention provides a vaccine accelerator factor (VAF) which is an in ovo nucleotide immuno-stimulant. The VAF contains one or more DNA constructs, each having a DNA molecule and a vector. Each of the DNA molecule contains one or more genes or gene fragme... | 05/02/2006 |
| 7029682 | Inactivated vaccine against feline calicivirosis Immunogenic preparations and vaccines, in particular which are inactivated, effective against feline calicivirosis, based on an FCV virus strain 431 as deposited at the CNCM under the accession number CNCM I-2166, or one of its equivalents, in a veterinarily accepta... | 04/18/2006 |
| 6984387 | Immunogenic peptides of foot-and-mouth disease viruses The present invention relates to FMDC vaccine based on peptides having a sequence of at least 8 amino acids, which corresponds to a partial sequence of the non-structural protein region of FMDV, which was selected by immunoreactivity with FMDV-specific antibodies or... | 01/10/2006 |
| 6982088 | Vaccine composition and stabilization method using high molecular weight PVP The invention concerns the stabilization of a vaccine composition maintained in liquid state by the use of high molecular weight polyvinylpyrrolidone, hence eliminating the use of albumen. The invention is of particular interest for vaccine compositions comprising a... | 01/03/2006 |
| 6927235 | Vaccine composition comprising iron phosphate as vaccine adjuvant The present invention relates to vaccine compositions comprising iron phosphate as adjuvant. This iron phosphate is in the form of particles, the size of which is between 0.01 μm and 300 μm; it can be obtained by mixing a solution of iron salt and of phosphate sal... | 08/09/2005 |
| 6673349 | Method of inactivating microorganisms This invention provides methods of inactivating a microorganism and preparing a vaccine including the step of applying to said microorganism a cross-linking agent simultaneously with a separate inactivant. This invention further relates to vaccines prepar... | 01/06/2004 |
| 6534066 | Inactivated vaccine against feline calicivirosis Immunogenic preparations and vaccines, in particular which are inactivated, effective against feline calicivirosis, based on an FCV virus strain 431 as deposited at the CNCM under the accession number CNCM I-2166, or one of its equivalents, in a veterinar... | 03/18/2003 |
| 6416762 | Anti-picornaviral ligands via a combinatorial computational and synthetic approach The present invention provides structure-based combinatorial libraries of compounds containing the functional group minima of picornaviruses including poliovirus and rhinovirus. The libraries can be used to screen for therapeutical antiviral compounds, e.... | 07/09/2002 |
| 6406702 | Multivalent in ovo avian vaccine A multivalent poultry vaccine is provided having two or more live biological agents or microbial components. Each live biological agent or microbial component is effective in preventing or treating an avian disease, and the multivalent vaccine is safe and... | 06/18/2002 |
| 6355246 | Feline calicivirus isolated from cat urine and vaccines thereof The present invention provides an isolated feline calicivirus and mutants thereof, which were isolated from the urine of a cat with lower urinary tract disorder. The present invention further provides nucleic acid clones of the virus, in particular, a clo... | 03/12/2002 |
| 6231863 | DNA sequences, molecules, vectors and vaccines for feline calicivirus disease and methods for producing and using same Nucleotide sequences obtained from the genome of the capsid gene of FCV strain 2280 wherein the splicing sites have been modified, so as to be deleted or inactivated are provided. The nucleotide sequences include DNA sequences that encode polypeptides, su... | 05/15/2001 |
| 6200576 | Swine vesicular disease virus and mutant strains and preparation process and use thereof The present invention relates to a gene of swine vesicular disease virus (SVDV) and the mutant strains of the gene, and the expression plasmids, the preparation process thereof. The invention also relates to a vaccine for use in the prophylaxis of swine v... | 03/13/2001 |
| 6048538 | Peptides derived from the non-structural proteins of foot and mouth disease virus as diagnostic reagents The present invention is directed to novel peptides derived from the non-structural proteins of the Foot-and-mouth Disease Virus (FMDV) and their use for the detection in animal body fluids of antibodies to FMDV. The peptides of the invention are useful f... | 04/11/2000 |
| 6048535 | Multivalent in ovo avian vaccine A multivalent poultry vaccine is provided having two or more live biological agents or microbial components. Each live biological agent or microbial component is effective in preventing or treating an avian disease, and the multivalent vaccine is safe and... | 04/11/2000 |
| 5965124 | Replication-competent recombinant viral vaccines and method of producing same Replication-competent recombinant viruses, particularly replication-competent recombinant polioviruses, which include (1) exogenous nucleic acid sequences which encode an exogenous polypeptide and (2) a nucleic acid sequence which encodes an artificial pr... | 10/12/1999 |
