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| Number | Title | Issue Date |
| 8029801 | HN epitope recognized by avian immune system and antigenic variant newcastle disease viruses carrying changes in the epitope The present invention relates to an epitope of HN protein in Newcastle disease virus which can be recognized by an avian immune system and an antibody against the epitope, a method for detecting a Newcastle disease virus by using the antibody, and an antigenic varia... | 10/04/2011 |
| 7951384 | Virus-like particles as vaccines for paramyxovirus The present invention discloses the method of making and using a novel, non-infective, paramyxovirus vaccine. Paramyxovirus structural proteins within a virus-like particle (VLP) comprise one example of such a vaccine. It is observed that the presence of matrix prot... | 05/31/2011 |
| 7547442 | Newcastle disease virus infectious clones, vaccines and new diagnostic assays The invention relates to the process for generating infectious Newcastle disease virus (NDV) entirely from cloned full-length cDNA and to the use of vaccines and diagnostic assays generated with and derived from said process. The process offers the possibility to mo... | 06/16/2009 |
| 7442379 | Recombinant Newcastle disease virus RNA expression systems and vaccines This invention relates to genetically engineered Newcastle disease viruses and viral vectors which express heterologous genes or mutated Newcastle disease viral genes or a combination of viral genes derived from different strains of Newcastle disease virus. The inve... | 10/28/2008 |
| 7332169 | Newcastle disease virus infectious clones, vaccines and new diagnostic assays The invention relates to a process for generating infectious Newcastle disease virus (NDV) entirely from cloned full-length cDNA and to the use of vaccines and diagnostic assays generated with and derived from the process. The process offers the possibility to modif... | 02/19/2008 |
| 7270990 | Virus production An improved process for recovery of virus from allantoic fluid of virus-infected chick embryos. Virus associated with granular and fibrous debris in the allantoic fluid can be disassociated from the debris and recovered, thereby increasing viral yield. Dissociation ... | 09/18/2007 |
| 7270548 | Electrical connector and method for connecting it to the glass pane of a motor vehicle An electrical connector for electrical devices such as heating panels, antennas, or the like that are provided on glass panes on motor vehicles, having at least one soldering area to be soldered onto the glass pane and having a connector area joined electrically con... | 09/18/2007 |
| 7223389 | Compositions and methods for treatment of cancer The present invention discloses lentogenic viral strains useful in the treatment of cancer. A preferred viral strain of Newcastle Disease Virus (NDV) is specifically characterized in terms of biological activities. The present invention further discloses treatment o... | 05/29/2007 |
| 7192588 | Vaccine composition and method of using the same The present invention relates to a stable compacted, compressed or hard tableted injectable composition, including a vaccine composition comprising at least one freeze dried antigenic component and a dissolution aid. A package containing the above injectable composi... | 03/20/2007 |
| 7070789 | Recombinant Newcastle disease virus nucleoprotein mutant as a marker vaccine The present invention provides a NDV mutant that is suited as a marker vaccine strain. The NDV mutant is not able to express an immunodominant epitope of the nucleoprotein (NP). ... | 07/04/2006 |
| 7041299 | Escape mutants of newcastle disease virus as marker vaccines A vaccine against Newcastle Disease contains one or more mutant immunogens of the NDW strain. The mutant immunogen lacks the antigenic binding site on the F glycoprotein which is recognized by the monoclonal antibody mAb 54. Reagent kits and assay methods help to di... | 05/09/2006 |
| 7037506 | Vaccine accelerator factor (VAF) for improvement of vaccinations in poultry The present invention provides a vaccine accelerator factor (VAF) which is an in ovo nucleotide immuno-stimulant. The VAF contains one or more DNA constructs, each having a DNA molecule and a vector. Each of the DNA molecule contains one or more genes or gene fragme... | 05/02/2006 |
| 6939957 | Nucleotide sequences of the nucleocapsid (NP) gene of a Malaysian velogenic Newcastle disease virus strain AF2240 The present invention relates to nucleotide sequences encoding the nucleocapsid (NP) protein and phosphoprotein (P) of Newcastle disease virus (NDV) and the production of the corresponding proteins with recombinant plasmids bearing the nucleotide sequences in Esc... | 09/06/2005 |
| 6919084 | Duck pneumovirus and corresponding vaccines An immunogenic preparation or vaccine against avian pneumovirosis, comprising an antigen of the avian pneumovirus strain C990427, in a vehicle or excipient which is acceptable from the veterinary point of view and, optionally, an adjuvant. ... | 07/19/2005 |
| 6833133 | Escape mutants of Newcastle disease virus as marker vaccines A vaccine against Newcastle Disease contains one or more mutant immunogens of the NDW strain. The mutant immunogen lacks the antigenic binding site on the F glycoprotein which is recognized by the monoclonal antibody mAb 54. Reagent kits and assay methods help to di... | 12/21/2004 |
| 6719979 | Newcastle disease virus infectious clones, vaccines and diagnostic assays The invention relates to the process for generating infectious Newcastle disease virus (NDV) entirely from cloned full-length cDNA and to the use of vaccines and diagnostic assays generated with and derived from the process. The process offers the possibility to mod... | 04/13/2004 |
| 6699479 | Recombinant newcastle disease virus as an embryo vaccine The present invention provides a NDV mutant which is suited as vaccine candidate for in ovo vaccination. The mutant expresses reduced levels of V protein and can safely be administered to chicken embryos before hatch.... | 03/02/2004 |
| 6664099 | Method for the preservation of viruses and mycoplasma A biologically-active material comprising a live virus or mycoplasma is preserved by a method of desiccation, without lyophilisation, in a matrix of glassy trehalose having a residual moisture content of not greater than 2%. The method comprises two vacuu... | 12/16/2003 |
| 6649372 | Helper-free rescue of recombinant negative strand RNA virus The present invention relates methods of generating infectious negative-strand virus in host cells by an entirely vector-based system without the aid of a helper virus. In particular, the present invention relates methods of generating infectious recombin... | 11/18/2003 |
| 6541001 | Vaccine composition and method of using the same The present invention relates to a stable compacted, compressed or hard tableted vaccine composition comprising at least one freeze dried antigenic component and a dissolution aid. A method to facilitate immunizing a subject against a disease comprising t... | 04/01/2003 |
| 6506385 | Live vaccines and methods of treatment therewith Disclosed herein are methods and pharmaceutical formulations for administering vaccines to birds. In preferred embodiments, the invention provides methods of administering live pathogenic virus vaccines to birds in ovo, more preferably, during the last qu... | 01/14/2003 |
| 6475770 | Processes for preparation of Marek's Disease using continuous mammalian cell lines The present invention relates to mammalian cell lines which efficiently support the growth and productive infection of Marek's Disease Virus at high titers. The present invention also relates to mammalian cell lines which have been engineered to support t... | 11/05/2002 |
| 6464984 | Avian polynucleotide vaccine formula An avian plasmid vaccine contains a plasmid, and a pharmaceutically acceptable carrier. The plasmid contains and expresses in vivo in an avian host cell a nucleic acid molecule having a sequence encoding the Newcastle disease virus HN protein. The plasmid... | 10/15/2002 |
| 6451323 | Recombinant newcastle disease virus RNA expression systems and vaccines This invention relates to genetically engineered Newcastle disease viruses and viral vectors which express heterologous genes or mutated Newcastle disease viral genes or a combination of viral genes derived from different strains of Newcastle disease viru... | 09/17/2002 |
| 6406702 | Multivalent in ovo avian vaccine A multivalent poultry vaccine is provided having two or more live biological agents or microbial components. Each live biological agent or microbial component is effective in preventing or treating an avian disease, and the multivalent vaccine is safe and... | 06/18/2002 |
| 6348197 | In ovo vaccination against Newcastle Disease The present invention is concerned with a vaccine for in ovo vaccination of poultry against Newcastle Disease Infections. This vaccine contains Newcastle Disease Viruses of the strain with the internal indication NDW, deposited at CNCM (Institut Pasteur) ... | 02/19/2002 |
| 6340464 | Adjuvants for vaccines Vaccine adjuvants comprising a liquid medium contain polymers with anionic constitutive repeating units and hydrophobic constitutive repeating units. Advantageously, the adjuvants are aqueous solutions of partially esterified polyacrylic acids. The novel ... | 01/22/2002 |
| 6299874 | Method of treatment A method of producing active immunity against a viral disease in an animal subject comprises administering to the subject a vaccine conjugate consisting essentially of a live virus and a neutralizing factor bound to the live virus. The neutralizing factor... | 10/09/2001 |
| 6146642 | Recombinant new castle disease virus RNA expression systems and vaccines This invention relates to genetically engineered Newcastle disease viruses and viral vectors which express heterologous genes or mutated Newcastle disease viral genes or a combination of viral genes derived from different strains of Newcastle disease viru... | 11/14/2000 |
| 6048535 | Multivalent in ovo avian vaccine A multivalent poultry vaccine is provided having two or more live biological agents or microbial components. Each live biological agent or microbial component is effective in preventing or treating an avian disease, and the multivalent vaccine is safe and... | 04/11/2000 |
| 6013261 | Recombinant Marek's disease virus (MDV) and vaccine A recombinant herpes virus is provided which efficiently expresses an exogenous protein of interest in an inoculated animal host to thereby endow the host with excellent immunization. A recombinant herpes virus which incorporates an exogenous gene express... | 01/11/2000 |
| 6001348 | Non-virulent Mycoplasma synoviae and vaccine thereof The present invention provides NAD-independent Mycoplasma synoviae of strain MS1. The invention also refers to microbiological cultures comprising Mycoplasma synoviae of this strain. Next to this, the invention refers to live vaccines derived from these s... | 12/14/1999 |
| 6001369 | Recombinant fowlpox viruses and uses thereof This invention provides a recombinant fowlpox virus comprising a foreign DNA sequence inserted into the fowlpox virus genomic DNA, wherein the foreign DNA sequence is inserted within a 4.2 kB EcoRI fragment of the fowlpox virus genomic DNA and is capable ... | 12/14/1999 |
| 5965138 | Recombinant chimeric virus and uses thereof This invention provides a recombinant herpesvirus of turkeys comprising a herpesvirus of turkeys viral genome which contains a foreign DNA sequence inserted within the EcoR1 #9 fragment of the herpesvirus of turkeys viral genome, and the foreign DNA seque... | 10/12/1999 |
| 5965139 | Chicken infectious anemia virus vaccine Novel sequences in the genome of a wild type isolate of chicken infectious anemia virus are described, The amino acid sequence of a polypeptide, VP1, encoded by a novel sequence is also disclosed. Additionally, disclosed are the unexpected properties of t... | 10/12/1999 |
| 5871742 | Recombinant Avipox virus encoding polypeptide of mycoplasma gallisepticum, and utilized a live vaccine A polypeptide exhibiting the antigenicity of Mycoplasma gallisepticum, a fused polypeptide comprising the above polypeptide and, connected to the N-terminus thereof, a signal membrane anchor of a type II outer-membrane polypeptide of a virus that infects ... | 02/16/1999 |
| 5843451 | Intranasal immunization against viral infection using viral glycoprotein subunit vaccine Method for immunizing against viral infection by administering intranasally an immunogenically effective amount of a viral envelope subunit vaccine comprising a glycoprotein complexed with a lipid.... | 12/01/1998 |
| 5756103 | Alvac canarypox virus recombinants comprising heterlogous inserts What is described is a modified vector, such as a recombinant poxvirus, particularly recombinant vaccinia virus, having enhanced safety. The modified recombinant virus has nonessential virus-encoded genetic functions inactivated therein so that virus has ... | 05/26/1998 |
| 5750111 | Mild newcastle disease virus vaccine The present invention provides the novel Newcastle disease virus strain C2 which is able to induce a solid immune response in poultry without adverse vaccination reactions.... | 05/12/1998 |
| 5744137 | Oil emulsion vaccines prepared with animal, vegetable, and synthetic oils using a mixture of nonionic surfactants A composition of a mixture of nonionic surfactants in water-in-oil emulsion vaccines allows the use of animal, vegetable, and synthetic oils as well as mineral oil and pristane. These non-mineral oil vaccines are as efficacious as mineral oil-containing v... | 04/28/1998 |
