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| Number | Title | Issue Date |
| 8182821 | Flu vaccine admixture of mannan and flu antigen The present invention relates to a vaccine composition comprising a carbohydrate polymer comprising mannose and flu antigen(s) (e.g. whole inactivated influenza virus) in admixture, and a method of immunising a subject comprising the step of administering the vaccin... | 05/22/2012 |
| 8128938 | Influenza virus vaccine composition and methods of use The present invention is directed to enhancing the immune response of a human in need of protection against IV infection by administering in vivo, into a tissue of the human, at least one polynucleotide comprising one or more regions of nucleic acid encoding an IV p... | 03/06/2012 |
| 8067013 | Multivalent avian influenza vaccines A vaccine composition and method which is effective in preventing or ameliorating Avian Influenza Virus infection is set forth herein. The vaccine contains at least two inactivated strains of avian influenza virus, wherein the combined haemoagglutinin (HA) total is ... | 11/29/2011 |
| 7964198 | Production of vaccines Means and methods for producing mammalian viruses, the method comprising infecting a culture of immortalized human cells with a virus, incubating the culture infected with virus to propagate the virus under conditions that permit growth of the virus, and to form a v... | 06/21/2011 |
| 7959930 | Rescue of influenza virus The invention relates to the field of influenza vaccine production. Influenza vaccines have been produced in embryonated hens' eggs for over 50 years, but recently there have been considerable efforts to develop cell culture systems for vaccine production. The inven... | 06/14/2011 |
| 7959931 | Influenza vaccines extemporaneously adsorbed to aluminium adjuvants Antigen and adjuvant components of an adjuvanted influenza vaccine are not mixed during manufacture, but are provided as separate components for extemporaneous mixing at the time of use, for example as a kit comprising (i) an antigen component, comprising an influen... | 06/14/2011 |
| 7943147 | dsRNAs as influenza virus vaccine adjuvants or immuno-stimulants Vaccine protection against acute or chronic viral infection is facilitated by using as an adjuvant or immuno-stimulant, a dsRNA together with an anti-influenza vaccine. ... | 05/17/2011 |
| 7931906 | Vero cell-based influenza virus strains and vaccines The present invention relates to isolated influenza virus strains suitable for increased vaccine production for mammals. The influenza virus strains contain at least one modified influenza protein that results in increased production of the influenza virus from a ma... | 04/26/2011 |
| 7910112 | Feline vaccines against avian influenza The present invention encompasses influenza vaccines, in particular avian influenza vaccines. The vaccine may be a recombinant poxvirus vaccine or an inactivated vaccine. The invention also encompasses recombinant poxvirus vectors encoding and expressing avian influ... | 03/22/2011 |
| 7785603 | Influenza virus vaccine composition and methods of use The present invention is directed to enhancing the immune response of a human in need of protection against IV infection by administering in vivo, into a tissue of the human, at least one polynucleotide comprising one or more regions of nucleic acid encoding an IV p... | 08/31/2010 |
| 7722884 | Vaccines and methods to treat canine influenza The present invention relates to providing new vaccines and treatments for the diseases related to canine influenza virus. It discloses influenza viral antigens, and methods of presenting these antigens to canines, especially dogs. It relates to attenuated and kille... | 05/25/2010 |
| 7682619 | Canine influenza virus The present invention relates to an isolate canine influenza virus. The present invention relates to an isolated nucleic acid molecule encoding a hemagglutinin from a canine influenza virus. The present invention also relates to the protein or polypeptide encoded by... | 03/23/2010 |
| 7674469 | Feline influenza vaccine and method of use This invention is directed to a vaccine and a method for using the vaccine to protect a feline from influenza virus infection. The vaccine comprises one or more antigens from one or more H3, N8, H7 or N7-type influenza viruses. ... | 03/09/2010 |
| 7601356 | Methods and compositions for increasing replication capacity of an influenza virus In certain aspects, the present invention provides methods for increasing the replication capacity of influenza viruses in hens' eggs and/or cell culture, recombinant and/or reassortant influenza viruses with increased replication capacity, and immunogenic and vacci... | 10/13/2009 |
| 7588769 | Viruses encoding mutant membrane protein A method to prepare viruses with a mutant membrane protein gene, and viruses obtained by the method, are provided. ... | 09/15/2009 |
| 7468187 | Canine influenza virus and related compositions and methods of use The present invention provides an isolated canine influenza virus of subtype H3N8 comprising an HA having SEQ ID NO: 4 or an amino acid sequence that is greater than 99% identical to SEQ ID NO: 4 , with the proviso that the amino acids at positions 94 and 233 are id... | 12/23/2008 |
| 7465456 | Multi plasmid system for the production of influenza virus Vectors and methods for the production of influenza viruses suitable as recombinant influenza vaccines in cell culture are provided. Bi-directional expression vectors for use in a multi-plasmid influenza virus expression system are provided. Additionally, the invent... | 12/16/2008 |
| 7442527 | Screening methods for identifying viral proteins with interferon antagonizing functions and potential antiviral agents The present invention relates, in general, to a screening method for identifying novel viral proteins with interferon antagonizing function using a transfection-based assay, and the use of such proteins in isolating various types of attenuated viruses for the develo... | 10/28/2008 |
| 7438919 | Cold-adapted equine influenza viruses The present invention provides experimentally-generated cold-adapted equine influenza viruses, and reassortant influenza A viruses comprising at least one genome segment of such an equine influenza virus, wherein the equine influenza virus genome segment confers at ... | 10/21/2008 |
| 7432045 | Method of inhibiting influenza infection with antiviral peptides This invention relates to peptides having antiviral properties. The antiviral peptides comprise membrane transiting peptides, and active fragments and derivatives of such peptides. The antiviral peptides exhibit activity against a broad spectrum of viruses, includin... | 10/07/2008 |
| 7425336 | Canine influenza vaccines The present invention encompasses influenza vaccines, in particular canine influenza vaccines. The vaccine may be a recombinant poxvirus vaccine or an inactivated vaccine. The invention also encompasses recombinant poxvirus vectors encoding and expressing influenza ... | 09/16/2008 |
| 7411058 | Cold-adapted equine influenza viruses The present invention provides experimentally-generated cold-adapted equine influenza viruses, and reassortant influenza A viruses comprising at least one genome segment of such an equine influenza virus, wherein the equine influenza virus genome segment confers at ... | 08/12/2008 |
| 7399477 | Cold-adapted equine influenza viruses The present invention provides experimentally-generated cold-adapted equine influenza viruses, and reassortant influenza A viruses comprising at least one genome segment of such an equine influenza virus, wherein the equine influenza virus genome segment confers at ... | 07/15/2008 |
| 7384642 | Canine influenza vaccines The present invention encompasses influenza vaccines, in particular canine influenza vaccines. The vaccine may be a recombinant poxvirus vaccine or an inactivated vaccine. The invention also encompasses recombinant poxvirus vectors encoding and expressing influenza ... | 06/10/2008 |
| 7354706 | Use of photopolymerization for amplification and detection of a molecular recognition event The invention provides methods to detect molecular recognition events. The invention also provides methods to detect the presence of or identify a target species based on its interaction with one or more probe species. The methods of the invention are based on ampli... | 04/08/2008 |
| 7344722 | Cold-adapted influenza virus The cold-adapted master strain A/Ann Arbor/6/60 7PI (H2N2) and progenitor wild type E2(3) viral strains have been deposited and their genomic sequences identified. Seven nucleotide differences were found between the sequences identified herein and the previously pub... | 03/18/2008 |
| 7339037 | Glycosylation-resistant cyanovirins and related conjugates, compositions, nucleic acids, vectors, host cells, methods of production and methods of using nonglycosylated cyanovirins The invention provides a method of inhibiting prophylactically or therapeutically an influenza viral infection in a host. The method comprises instilling into or onto a host a cell producing an antiviral protein, antiviral peptide, or antiviral conjugate comprising ... | 03/04/2008 |
| 7329639 | Peptide useful in immunomodulation The present invention provides peptides and polynucleotides, and their use for immunomodulation, immunotherapy and vaccine particularly for anti-cancer therapy, and for diagnosis purposes. The immunomodulatory effect includes induction of proliferation and activatio... | 02/12/2008 |
| 7316813 | Influenza vaccine composition An inactivated influenza virus preparation is described which comprises a haemagglutinin antigen stabilized in the absence of thiomersal, or at low levels of thiomersal, wherein the haemagglutinin is detectable by a SRD assay. The influenza virus preparation may com... | 01/08/2008 |
| 7312064 | DNA transfection system for the generation of infectious influenza virus The present invention is based on the development of a dual promoter system (preferably a RNA pol I-pol II system) for the efficient intracellular synthesis of viral RNA. The resultant minimal plasmid-based system may be used to synthesize any RNA virus, preferably ... | 12/25/2007 |
| 7279167 | Infectious Salmon Anaemia virus vaccine This invention relates to Infectious Salmon Anaemia Virus (ISAV) antigenic polypeptides and nucleic acid molecules encoding them, as well as vaccines, transformed cells and transgenic fish. The antigenic polypeptides are able to elicit an immune response in immunize... | 10/09/2007 |
| 7270990 | Virus production An improved process for recovery of virus from allantoic fluid of virus-infected chick embryos. Virus associated with granular and fibrous debris in the allantoic fluid can be disassociated from the debris and recovered, thereby increasing viral yield. Dissociation ... | 09/18/2007 |
| 7267963 | Modified plant viruses and methods of use thereof The present invention relates to modulating the nature and/or level of an immune response to a molecule. In particular, the invention relates to effecting an increase in the TH1 immune response to molecules such as, but not limited to, antigens or immunogens. The in... | 09/11/2007 |
| 7262045 | Methods of producing influenza vaccine compositions Methods and compositions for the optimization of production of influenza viruses suitable as influenza vaccines are provided. ... | 08/28/2007 |
| 7244435 | DNA vaccine expressing HA1 of equine-2 influenza virus The invention is for a DNA vaccine expressing the hemagglutinin (HA1) gene of equine-2 influenza virus. By engineering a stop codon within HA1, expression of HA1 is ensured. By encapsulation of the DNA vaccine in liposome and by intranasal inoculation, it is suffici... | 07/17/2007 |
| 7238349 | Composition The invention provides a monovalent influenza vaccine comprising a low dose of egg-derived influenza virus antigen from an influenza virus strain that is associated with a pandemic outbreak or has the potential to be associated with a pandemic outbreak, in combinati... | 07/03/2007 |
| 7226775 | Method of removing endotoxin from vaccines A method of removing bacterial endotoxin from a pharmaceutical process solution is disclosed. In one embodiment, the method comprises treating the solution with a surfactant effective to dissociate the endotoxin from a pharmaceutical drug or vaccine substance in the... | 06/05/2007 |
| 7202225 | Therapeutic delivery compositions and methods of use thereof The present invention relates to compositions and methods for delivery of antisense oligonucleotides or other nucleic acid sequences. The present invention comprises a delivery composition comprising an administerable admixture of an effective amount of a nucleic ac... | 04/10/2007 |
| 7201910 | Nucleic acid and amino acid sequences of infectious salmon anaemia virus and their use as vaccines The present invention provides the use of nucleic acid sequences and/or amino acid sequences in the preparation of a vaccine for the protection of fish against infectious salmon anaemia virus. Specifically, such vaccines contain at least one nucleic acid sequence wh... | 04/10/2007 |
| 7201909 | Cold-adapted equine influenza viruses The present invention provides experimentally-generated cold-adapted equine influenza viruses, and reassortant influenza A viruses comprising at least one genome segment of such an equine influenza virus, wherein the equine influenza virus genome segment confers at ... | 04/10/2007 |
