Quotables
"I hate what they've done to my child...I would never let my own children watch it. "
Vladimir Zworykin, television pioneer ; Talking about an invention in which he played a critical role.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 6673355 | Rotavirus enterotoxin NSP4 and methods of using same The rotavirus nonstructural glycoprotein, NSP4, performs multiple functions in the virus replication cycle, especially during viral morphogenesis. Specifically, NSP4 is an intracellular receptor that mediates the acquisition of a transient membrane envelo... | 01/06/2004 |
| 6673354 | Compositions and methods for treating papillomavirus-infected cells By virtue of the present invention, there is provided methods and compositions for interfering with the proliferation of cells infected and/or transformed by papillomaviruses. The processes and compositions of this invention may be used to treat any mamma... | 01/06/2004 |
| 6673349 | Method of inactivating microorganisms This invention provides methods of inactivating a microorganism and preparing a vaccine including the step of applying to said microorganism a cross-linking agent simultaneously with a separate inactivant. This invention further relates to vaccines prepar... | 01/06/2004 |
| 6669947 | Stratified and cryogenically stored vaccines, process for their preparation A composition comprising at least one antigenic medium and at least one adjuvant, wherein the at least one antigenic medium and the at least one adjuvant each comprise one or more phases which are distinct from each other when the composition is in a soli... | 12/30/2003 |
| 6667295 | DNA vaccine against feline immunodeficiency virus The present invention is directed to vaccine compositions that can be used to protect cats against feline immunodeficiency virus. More particularly, the present invention relates to polynucleotide molecules that can be used as vaccine components against f... | 12/23/2003 |
| 6663872 | Hemorrhagic enteritis virus DNA sequences, proteins encoded thereby and various uses thereof The present invention relates to a DNA sequence comprising a nucleotide sequence encoding Hemorrhagic Enteritis virus. It is well known to the man of the art that determining the complete sequence of a virus enables the isolation and identification of the... | 12/16/2003 |
| 6660272 | Porcine circoviruses, vaccines and diagnostic reagents The invention relates to new porcine circovirus strains isolated from pulmonary or ganglionic samples obtained from farms affected by the post-weaning multisystemic wasting syndrome (PMWS). It relates to purified preparations of these strains, conventiona... | 12/09/2003 |
| 6656481 | Vaccinal preparations Vaccinal preparations comprising an antigen such as tumor-associated antigens and viral antigens, together with a hydrophobized polysaccharide as adjuvant, e.g., hydrophobized polysaccharides containing a saccharide unit whose primary hydroxyl group is re... | 12/02/2003 |
| 6649169 | Cold-adapted equine influenza viruses The present invention provides experimentally-generated cold-adapted equine influenza viruses, and reassortant influenza A viruses comprising at least one genome segment of such an equine influenza virus, wherein the equine influenza virus genome segment ... | 11/18/2003 |
| 6649172 | Amphipathic aldehydes and their uses as adjuvants and immunoeffectors This invention relates to novel aldehyde containing compounds and their uses as adjuvants and immunoeffectors.... | 11/18/2003 |
| 6649167 | Papillomavirus truncated L1 protein and fusion protein constructs Vaccine formulations comprising viral capsomeres are disclosed along with methods for their production. Therapeutic and prophylactic methods of use for the vaccine formulations are also disclosed.... | 11/18/2003 |
| 6641819 | Porcine reproductive and respiratory syndrome vaccine, based on isolate JA-142 Substantially avirulent forms of atypical porcine reproductive and respiratory syndrome (PRRS) virus and corresponding vaccines are provided which result from cell culture passaging of virulent forms of PRRS. The resultant avirulent atypical PRRS virus is... | 11/04/2003 |
| 6641818 | Cellular proteins which mediate herpesvirus entry A cellular herpesvirus entry protein, or a mutant, a homolog, a derivative, a variant or a biologically active fragment thereof, suspended in a pharmaceutically active carrier in an amount effective to inhibit entry of an alphaherpesvirus into a cell, whe... | 11/04/2003 |
| 6635472 | Retrovirus and viral vectors This invention relates to the fields of genetic engineering, virus replication and gene transfer. More specifically, this invention relates to polynucleotide construct, recombinant virus, transposon, and their vectors, wherein an ori derived from a DNA vi... | 10/21/2003 |
| 6635261 | Adjuvant and vaccine compositions containing monophosphoryl lipid A The invention pertains to adjuvant and vaccine compositions of monophosphoryl lipid A, sugar and optionally an amine based surfactant, which when frozen and thawed or lyophilized and reconstituted reform a colloidal suspension having a light transmission ... | 10/21/2003 |
| 6635258 | Herpes simplex virus VP22 vaccines and methods of use Vaccines containing herpes simplex virus (HSV) VP22 polypeptides capable of eliciting a cellular immune response and methods for treating and preventing HSV infections using the vaccines are disclosed. The vaccines can include additional HSV polypeptides,... | 10/21/2003 |
| 6635253 | Composition for enhancing immunological effects An object of the present invention is to provide a composition for enhancing the immunological effects of a vaccine for viruses, bacteria and/or infectious disease pathogens, containing a stable activity-type provitamin; a method for enhancing the immunol... | 10/21/2003 |
| 6632435 | CTL epitope analogs We have screened the HCMV-specific T cell clone, 33F4, with a nonamer PS-SCL based on SEQ ID NO: 1, and described a series of analog peptides that are recognized with greater affinity than the native peptide sequence.... | 10/14/2003 |
| 6632445 | Unit dosage forms for the treatment of herpes simplex The components of this invention are chosen because of their complementarity for the prevention or treatment of diseases caused by the herpes simplex virus. L-Lysine favorably increases the physiologic immunomodulation necessary for defense against this v... | 10/14/2003 |
| 6632664 | Avian infectious herpesvirus recombinants and recombinant vaccines prepared with the use of the same An avian infectious recombinant herpesvirus is prepared by inserting a foreign gene, in particular a heterologous antigen gene, into an insertion site in an untranslated genetic region in the genome. A chicken vaccine comprising such a recombinant virus i... | 10/14/2003 |
| 6632431 | Anti-idiotypic antibody against FimH adhesion of uropathogenic type I-fimbriated Escherichia coli, compositions containing same and method for using same The present invention relates to an anti-idiotypic antibody or antigen-binding fragment against FimH adhesin of uropathogenic Type I-fimbriated Escherichia coli and an immunizing composition containing such an anti-idiotypic antibody or antigen-binding fr... | 10/14/2003 |
| 6632438 | Recombinant poxvirus cytomegalovirus, compositions, and uses Attenuated recombinant viruses containing DNA encoding an HCMV antigen, as well as methods and compositions employing the viruses, expression products therefrom, and antibodies generated from the viruses or expression products, are disclosed and claimed. ... | 10/14/2003 |
| 6627418 | Detection of human herpes virus 6 (HHV6) The present invention relates to methods for detecting viral pathogens, particularly human herpes virus S (HHV6), preferably using polymerase chain reaction (PCR) techniques. Primer sequences useful in these methods are also described. In a first aspect, ... | 09/30/2003 |
| 6623739 | Vaccines The present invention provides vaccine compositions comprising an oil-in-water emulsion optionally with 3 De-O-acylated monophosphoryl lipid A and QS21. The vaccine compositions are potent inducers of a range of immune responses.... | 09/23/2003 |
| 6620416 | Method for treating HIV The present invention relates to peptides of one or more portions of the human chorionic gonadotropin ଲ-chain as well as methods for treatment and prevention of diseases, including HIV infection, using human chorionic gonadotropin, employing the &#x... | 09/16/2003 |
| 6616930 | Peptide fragment of respiratory syncytial virus protein G, immunogenic agent, pharmaceutical composition containing it and preparation method A polypeptide useful as an immunogen element and characterized in that it is carried on the peptide sequence between amino acid residues 130-230 of the G protein sequence of the human respiratory syncytial virus of sub-groups A and B, or of the bovine res... | 09/09/2003 |
| 6613556 | Adaptation of virus to vertebrate cells The present invention provides a method for replicating virus to high titer in cultured mammalian cells by infecting the mammalian cells with the high titer virus strain to obtain infected cells, specifically, attenuated dengue virus strains of serotype 1... | 09/02/2003 |
| 6613333 | Immunodominant human T-cell epitopes of hepatitis C virus The present invention relates to a polypeptide of about 8 to about 100 amino acids comprising or consisting of at least 8 contiguous amino acids selected from the core, and/or the NS3 regions of the HCV polyprotein, with said contiguous amino acids contai... | 09/02/2003 |
| 6610304 | Liposomes containing multiple branch peptide constructions for use against human immunodeficiency virus The incorporation of multiple branch peptide constructions having activity against HIV into liposomes of sufficient size for white blood cell internalization (e.g. greater than 150 nm and preferably approximately 250-400 nm. ) has been shown to increase t... | 08/26/2003 |
| 6610305 | Safe attenuated bovine viral diarrhea viruses for use in pregnant cows This invention relates to the use of specifically attenuated live BVD (bovine viral diarrhea) viruses for the preparation of a vaccine for use in the prevention and/or treatment of BVDV infections in breeding stocks of cattle, pregnant cows and for fetal ... | 08/26/2003 |
| 6610473 | Peptides for inhibiting HPV E6-proteins The present invention relates to peptides suited for inhibiting HPV-E6 proteins, DNAs encoding them and the use of both, particularly for eliminating HPV tumor cells.... | 08/26/2003 |
| 6610303 | Papilloma viruses, products for the detection thereof as well as for treating diseases caused by them This invention relates to a DNA coding for a peptide of a papilloma virus major capsid protein and a papilloma virus genome, respectively. In addition, this invention concerns proteins coded by the papilloma virus genome and antibodies directed against th... | 08/26/2003 |
| 6607732 | ISCOM or ISCOM-matrix comprising a mucous targetting substance and an antigen An immunogenic complex includes at least one glycoside and at least one lipid. The complex further contains a) at least one mucosal surface targeting protein, protein derivative or carbohydrate that targets lymphatic tissue and induces an immune response ... | 08/19/2003 |
| 6605281 | Human papillomavirus vectors for the episomal transduction of host cells and method of making same A replicon for delivery of a transgene for episomal gene expression in a mammalian host cell includes a transgene having an open reading frame or other nucleic acid sequence for transcription into RNA and under the transcriptional control of a first surro... | 08/12/2003 |
| 6605284 | Gene coding for the measles virus mutant antigen Disclosed is a measles virus mutant gene coding for a measles virus mutant H protein antigen, wherein said gene coding for a measles virus mutant H protein antigen is at least one member selected from the group consisting of the following genes (a) to (c)... | 08/12/2003 |
| 6605283 | Nucleotide sequence for the Avian Metapneumovirus (Colorado) attachment glycoprotein gene The nucleic acid and the corresponding amino acid sequence for the attachment glycoprotein of Avian Metapneumovirus (Colorado) Type C strain is provided. The nucleotide sequence is 1,321 base pairs with only one substantial open reading frame encoding a g... | 08/12/2003 |
| 6605280 | Interleukin-18 binding proteins, their preparation and use for blocking the activity of IL-18 Interleukin-18 binding proteins which are capable of binding IL-18 and/or modulating and/or blocking IL-18 activity are provided. Methods for their isolation and recombinant production, DNAs encoding them, DNA vectors expressing them, vectors useful for t... | 08/12/2003 |
| 6599508 | Papilloma virus-like particles, fusion proteins as well as processes for their production The invention relates to the recombinant production of proteins as well as VLPs which are suitable as a vaccine for therapeutic and prophylactic vaccination. The invention also relates to processes for the production and purification of recombinant papill... | 07/29/2003 |
| 6596924 | Graft animal model for high induction of papillomas, the propagation of papillomavirus and evaluation of candidate therapeutic agents The present invention relates to a graft animal model for propagating papilloma virus and for evaluating and testing candidate therapeutic agents against papilloma virus. The animal model comprises, a recipient animal engrafted with injured skin graft inf... | 07/22/2003 |
| 6596280 | Method for generating birnavirus from synthetic RNA transcripts A system for the generation of live Bimavirus such as infectious bursal disease virus (IBDV), a segmented double-stranded (ds) RNA virus of the Bimaviridae family, using synthetic transcripts derived from cloned DNA has been developed. Independent full-le... | 07/22/2003 |
