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Class 424/203.1 - Combination of antigens from multiple bacterial species (e.g., multivalent bacterial vaccine, etc.)


Subclass of Class 424 - Drug, bio-affecting and body treating compositions
Definition: Subject matter involving a combination of antigens from
No. of patents: 228
Last issue date: 09/27/2011


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NumberTitleIssue Date
8025887Avirulent, immunogenic flavivirus chimeras
Chimeric flaviviruses that are avirulent and immunogenic are provided. The chimeric viruses are constructed to contain amino acid mutations in the nonstructural viral proteins of a flavivirus. Chimeric viruses containing the attenuation-mutated nonstructural ...
09/27/2011
8007815Combination B/C vaccines
Combination vaccines for treating or preventing Neisseria meningitidis infection are described. The vaccines include Neisseria meningitidis serogroup B proteoliposomic vesicles and Neissera meningitidis serogroup C conjugated oligosaccharides.
08/30/2011
7988978Composition and method for controlling intestinal pathogenic organisms
An antigen composition for stimulating an immune response in an inoculated avian species to at least one intestinal pathogenic organism includes seven field strains of E. coli, Pseudomona aeruginosa, Aerobacter aerogenes, Salmonella enteritidis, Salmonella typhim...
08/02/2011
7780966Artificial invaplex
An artificial invasin complex is prepared from purified or recombinantly prepared invasins and gram negative bacteria lipopolysaccharides. Typically, IpaB is mixed with IpaC to form a IpaB:IpaC complex. This invasin protein complex is then mixed with the lipopolysac...
08/24/2010
7749509Treatment of autism using probiotic composition
A method of treating autism using a probiotic composition including the bacilli (1) Bacillus subtilis, (2) Bacillus coagulans, and (3) Enterococcus faecium. The composition may further include a carrier medium, such as fructo-oligo-saccharides (...
07/06/2010
7731976Treatment of irritable bowel syndrome using probiotic composition
A method of treating irritable bowel syndrome using a probiotic composition including the bacilli (1) Bacillus subtilis, (2) Bacillus coagulans, and (3) Enterococcus faecium. The composition may further include a carrier medium, such as fructo-o...
06/08/2010
7442374Composition for increasing the survival to slaughter rate of piglets
This invention relates to a method for treating or preventing (including immunising against) post-wearing multisystemic wasting syndrome (PMWS) and/or porcine dermatitis and nephropathy syndrome (PDNS) in a subject comprising administering an effective amount of a p...
10/28/2008
7429388Vaccine for nontypeable infection
This invention provides a method for identifying strains of nontypeable Haemophilus influenzae that can be used as immunogenic compositions having specificity against a plurality of Haemophilus influenzae strains. The invention also provides compositio...
09/30/2008
7416734Vaccines for and methods of use
The invention of novel, effective vaccines against Mycoplasma bovis for use in cattle is described. These vaccines demonstrate no undesirable side effects and protect against M. bovis related disease, such as contagious mastitis, respiratory pneumonia,...
08/26/2008
7413743Active immunization using a siderophore receptor protein
The invention provides a vaccine for immunizing poultry and other animals against infection by a gram-negative bacteria, and a method of immunizing an animal using the vaccine. The vaccine may contain purified siderophore receptor proteins derived from a single stra...
08/19/2008
7384645Outer membrane vesicles from gram negative bacteria and use as a vaccine
A composition is prepared from a mixture of different vesicles, such as outer membrane vesicles (OMVs) and vaccines are based thereon. Another composition comprises in a single vesicle a combination of antigens and/or other vesicle components deriving from separate ...
06/10/2008
7381414Mycoplasma vaccine, method of making, and application thereof
The present invention provides a mycoplasma vaccine, its preparation and application thereof. The foregoing mycoplasma vaccine comprises inactivated Mycoplasma hyorhinis ATIT-7 only or the mixture of inactivated Mycoplasma hyorhinis ATIT-7 and inactiva...
06/03/2008
7368537Subunit vaccine against respiratory syncytial virus infection
The present invention relates generally to methods of treating or preventing RSV infections, and more specifically, to compositions, and the use thereof, comprising one or more RSV G protein immunogen or fragment thereof capable of eliciting protective immunity with...
05/06/2008
7332174Mutant forms of cholera holotoxin as an adjuvant
Mutant cholera holotoxins having single or double amino acid substitutions or insertions have reduced toxicity compared to the wild-type cholera holotoxin. The mutant cholera holotoxins are useful as adjuvants in antigenic compositions to enhance the immune response...
02/19/2008
7323175Immunogenicity of glucan binding protein
Immunogenic compositions and subunit vaccines for dental caries are described which comprise peptide subunits of glucan binding protein-B and peptide subunits of glucan binding protein-B in combination with peptide subunits of glucosyltransferase. Methods of provoki...
01/29/2008
7309493Inactivated bovine scours vaccines, process and method of preventing bovine scours
Inactivated scours vaccines for immunization and protection of bovine animals from disease caused by infection with bovine rotavirus and bovine coronavirus, which comprise and effective amount of at least one inactivated viral strain are described. Polyvalent inacti...
12/18/2007
7300659Enterohemorrhagic vaccine
Compositions and methods for stimulating an immune response against a secreted enterohemorragic Escherichia coli (EHEC) antigen are disclosed. The compositions comprise EHEC cell culture supernatants. ...
11/27/2007
7297338Avian vaccine composition for the protection of poultry against disease and infection caused by and Salmonella
There is provided a vaccine composition comprising a combination of a genetic deletion mutant S. typhimurium microorganism and a genetic deletion mutant E. coli microorganism, suitable for mass application to poultry. Also provided is a safe and effect...
11/20/2007
7285281Mutant forms of cholera holotoxin as an adjuvant
Mutant cholera holotoxins comprising a cholera toxin subunit A having single amino acid substitutions in the amino acid positions 16 or 72 or a double amino acid substitution in the amino acid positions 16 and 68 or 68 and 72 have reduced toxicity compared to the wi...
10/23/2007
7279169Mucosal DTPa vaccines
Mucosal DTPa vaccines, especially intranasal vaccines, comprising (a) a diphtheria antigen, a tetanus antigen and an acellular pertussis antigen, and (b) a detoxified mutant of cholera toxin (CT) or E. coli heat labile toxin (LT). Component (b) acts as a muco...
10/09/2007
7279163Water-in-oil emulsion vaccines
Oil-in-Water emulsion vaccines induce higher biliary IgA responses which decrease mucosal/internal organ invasion and fecal shedding, increase specific activity of serum IgG subpopulations, and increase the relative avidity index of serum IgG subpopulations, resulti...
10/09/2007
7270827Multivalent streptococcal vaccine compositions and methods for use
Compositions and methods for making and using therapeutic formulations of multivalent hybrid polypeptides comprising immunogenic peptides of M proteins from various different serotypes of group A streptococci and antibodies thereto are provided. Also provided are nu...
09/18/2007
7247307Vaccines against O157 infection
This invention relates to conjugates of the O-specific polysaccharide of E. coli O157 with a carrier, and compositions thereof, and to methods of using of these conjugates and/or compositions thereof for eliciting an immunogenic response in mammals, including...
07/24/2007
7247309Coccidiosis vaccines
The present invention relates to coccidia strains and, in one embodiment, to microbiological cultures comprising such strains. In preferred embodiments, the coccidia strains are selected for tolerance to one group of coccidiostatic drugs, sensitivity to a second gro...
07/24/2007
7235242IgA1 protease fragment as carrier peptides
The present invention is concerned with a fragment of IgA1-protease having 40 to 200 amino acid residues and comprising at least 40 amino acids of an amino acid sequence as shown in SEQ ID NO:1, beginning with the amino acid in any one of positions 1 to 5 and ending...
06/26/2007
7235243Immunological combination compositions and methods
Immununological compositions and methods for making and using them. The compositions contain at least one antigen and at least one lipoprotein and optionally an adjuvant. The lipoprotein can itself be antigenic or immunogenic. The antigen can be influenza HA and the...
06/26/2007
7226588Non-toxic mutants of pathogenic gram-negative bacteria
A method is provided for identifying, isolating, and producing htrB mutants of gram-negative bacterial pathogens. The method comprises mutating the htrB gene of a gram-negative bacterial pathogen so that there is a lack of a functional HtrB protein, resulting in a m...
06/05/2007
7204993vaccine
A composition prepared from intact killed cells of isolated β-hemolytic Streptococcus agalactiae and a concentrated extract of a culture of β-hemolytic Streptococcus agalactiae, is effective for the protection of fish against infection by the same an...
04/17/2007
RE39494Inactivated mycoplasma hyopneumoniae and uses therefor
The invention relates to a method for making an inactivated vaccine of Mycoplasma hyopneumoniae by inactivating the bacteria with Thimerosal. The resulting bacterin is mixed with an adjuvant of aluminum hydroxide and DEAE dextran and injected into pigs. The r...
02/27/2007
7169392serogroup B glycoconjugates and methods of producing the same
The present invention pertains generally to novel Neisseria meningitidis serogroup B glycoconjugates. More particularly, the invention pertains to glycoconjugates formed from a Neisseria meningitidis serogroup B capsular oligosaccharide derivative (Men...
01/30/2007
7169394bacterin vaccine
The invention provides an improved Mycoplasma hyopneumoniae bacterin vaccine composition, which advantageously provides immunity from infection after a single administration. The composition comprises an inactivated Mycoplasma hyopneumoniae bacterin an...
01/30/2007
7163682Glucan binding protein and glucosyltransferase immunogens
Immunogenic compositions and subunit vaccines for dental caries are described which comprise peptide subunits of glucan binding protein-B and peptide subunits of glucan binding protein-B in combination with peptide subunits of glucosyltransferase. Methods of provoki...
01/16/2007
7160549Methods for making compositions including gram negative microbial polypeptides
The present invention provides methods for making compositions including siderophore receptor polypeptides and porins from gram negative microbes. The methods include providing a gram negative microbe, disrupting the microbe, solubilizing the disrupted microbe, and ...
01/09/2007
7157245Neisserial vaccine compositions and methods
Methods and compositions for the treatment of microbial infection, and in particular meningococcal disease, comprise a commensal Neisseria or an extract of a commensal Neisseria. Further methods and compositions comprise commensal Neisseria whic...
01/02/2007
7147857Methods for treating high somatic cell counts
The present invention provides methods for treating an animal having a high somatic cell count. The methods include administering compositions including siderophore receptor polypeptides and porins from gram negative microbes, and preferably, lipopolysaccarhide at a...
12/12/2006
7144580outer membrane protein P1pE as a vaccine or vaccine component against shipping fever
Vaccines and methods against M. haemolytica infections in cattle. The vaccine compositions include a recombinant outer membrane protein of M. haemolytica designated PlpE and/or subunits thereof, alone or in combination with other antigenic components, ...
12/05/2006
7138125Methods for treating an animal for low milk production
The present invention provides methods for treating an animal for low milk production. The methods include administering compositions including siderophore receptor polypeptides and porins from gram negative microbes, and preferably, lipopolysaccarhide at a concentr...
11/21/2006
7138124Polypeptides obtained from gram negative microbes
The present invention provides compositions including at least two siderophore receptor polypeptides and at least two porins from a gram negative microbe, and preferably, lipopolysaccharide at a concentration of no greater than about 10.0 endotoxin units per millili...
11/21/2006
7135191Urogenital or anorectal transmucosal vaccine delivery system
The invention is directed to a suppository based vaccine delivery system for immunizing against urogenital and anorectally transmitted infectious disease in humans and animals and a method for treating the same. More particularly, this invention is directed to a sup...
11/14/2006
7128919Group B streptococcus polypeptides nucleic acids and therapeutic compositions and vaccines thereof
This invention provides isolated nucleic acids encoding polypeptides comprising amino acid sequences of streptococcal matrix adhesion (Ema) polypeptides. The invention provides nucleic acids encoding Group B streptococcal Ema polypeptides EmaA, EmaB, EmaC, EmaD and ...
10/31/2006
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