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Microwave Oven With Removable Storage Cassette in Dashboard of Motor Vehicle
A microwave oven adapted for use within a motor vehicle dashboard area. The microwave oven has a removable storage cassette, and slidable platforms for securing and serving containers of beverages and foods.
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| Number | Title | Issue Date |
| 8148331 | Method for the preparation of growth hormone and antagonist thereof having lower levels of isoform impurities thereof The present invention is directed generally to recombinant methods for making a desired polypeptide. These method(s) yield a polypeptide product containing reduced levels of isoform impurities thereof. In particular, the present invention is directed to (1) a recomb... | 04/03/2012 |
| 8025886 | Modified VEGF-A with improved angiogenic properties The present invention is directed to methods and compositions for making and using chimeric polypeptides that comprise a VEGFR-2 ligand. The chimeric molecules of the present invention retain VEGFR-2 binding activity and an enhanced angiogenic activity as compared t... | 09/27/2011 |
| 7939080 | HER-2 binding antagonists There is disclosed a pharmaceutical composition for treating solid tumors that overexpress HER-2, comprising an agent selected from the group consisting of (a) an isolated polypeptide having from about 50 to 79 amino acids taken from the sequence of SEQ ID NO:1, whe... | 05/10/2011 |
| 7790174 | G-CSF polypeptides and uses thereof The present invention relates to G-CSF polypeptides and their uses, particularly for therapeutic or prophylactic treatment in human subjects. The invention also relates to nucleic acids encoding said polypeptides, vectors comprising such nucleic acids and recombinan... | 09/07/2010 |
| 7713533 | Active complex of α-lactalbumin (HAMLET) and cofactor The use of a biologically active complex of α-lactalbumin, selected from HAMLET (human α-lactalbumin made lethal to tumour cells) or a biologically active modification thereof, or a biologically active fragment of either of these, in the preparation of a medicamen... | 05/11/2010 |
| 7585509 | Erb-2 receptor targeting peptide The ErbB-2 receptor, a member of the tyrosine kinase type 1 family of receptors, has been implicated in many human malignancies. Bacteriophage display technology was employed to identify peptides that bound to the extracellular domain of human ErbB-2. The peptide KC... | 09/08/2009 |
| 7482014 | Melanoma therapy Methods for treating treatment-naive as well as treatment-experienced patients having melanoma to increase the progression-free survival time involving administering a therapeutically effective amount of pegylated interferon-alpha, e.g., preferably pegylated interfe... | 01/27/2009 |
| 7442376 | Glycoprotein hormone compositions containing two β subunits Forms of differentially acting glycoprotein hormones are disclosed. These compositions are of the formula β1-(linker1)m-α-(linker2)n-β2; (1) β1-(linker1 | 10/28/2008 |
| 7430476 | Method for identification of t-cell epitopes and use for preparing molecules with reduced immunogenicity This invention relates to a novel approach for identification of T-cell epitopes, that give rise to an immune reaction in a living host. By means of this novel method biological compounds can be generated which have a no or at least a reduced immunogenicity when exp... | 09/30/2008 |
| 7427655 | Synthetic immunogenic but non amyloidogenic peptides homologous to amyloid β for induction of an immune response to amyloid β and amyloid deposits The present invention relates to synthetic immunogenic but non-amyloidogenic peptides homologous to amyloid β which can be used alone or conjugated to an immunostimulatory molecule in an immunizing composition for inducing an immune response to amyloid β peptides ... | 09/23/2008 |
| 7378096 | Stress protein compositions and methods for prevention and treatment of cancer and infectious disease Pharmaceutical compositions comprising a stress protein complex and related molecules encoding or cells presenting such a complex are provided. The stress protein complex comprises an hsp110 or grp170 polypeptide complexed with an immunogenic polypeptide. The immuno... | 05/27/2008 |
| 7361644 | Specific antagonist for both E- and P-selectins Compounds and methods are provided for modulating in vitro and in vivo processes mediated by selectin binding. More specifically, selectin modulators and their use are described, wherein the selectin modulators that modulate (e.g., inhibit or enhance) a selectin-med... | 04/22/2008 |
| 7341730 | Inhibitors of angiogenesis and tumor growth This invention provides for polypeptides that have surprising anti-angiogenic activity. These peptides are derived from Saposin B, a previously known protein involved in the hydrolysis of sphingolipids. In addition, methods of treating mammals with these anti-angiog... | 03/11/2008 |
| 7320806 | Compositions and methods for treating NIDDM and other conditions and disorders associated with AMPK regulation Compositions and methods are provided to increase glucose uptake in a cell as well as to treat a patient suffering from a condition or disorder associated with AMPK regulation. Particularly contemplated compositions include a compound that is isolated from a plant t... | 01/22/2008 |
| 7320793 | Molecular antigen array The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising an ordered and repetitive antigen or antigenic determinant array. The invention also provides a process for produc... | 01/22/2008 |
| 7270822 | Active complex of alpha-lactalbumin (hamlet) and cofactor The use of a biologically active complex of α-lactalbumin, selected from HAMLET (human α-lactalbumin made lethal to tumour cells) or a biologically active modification thereof, or a biologically active fragment of either of these, in the preparation of a medicamen... | 09/18/2007 |
| 7264810 | Molecular antigen array The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising an ordered and repetitive antigen or antigenic determinant array. The invention also provides a process for produc... | 09/04/2007 |
| 7208157 | Proteolysis targeting chimeric pharmaceutical The present invention is based on the discovery of a composition that provides targeted ubiquitination. Specifically the composition contains a ubiquitin pathway protein binding moiety which recognizes a ubiquitin pathway protein and a targeting moiety which recogni... | 04/24/2007 |
| 7201905 | Bi-functional cancer treatment agents A novel fusion protein, comprising a receptor-antagonizing domain and a positive immunomodulator domain, characterized, for example, by its ability to block apoptosis and/or inhibit endocrine response, is useful in treating cancer. For example, a human prolactin ant... | 04/10/2007 |
| 7202346 | Antibodies to non-shed Muc1 and Muc16, and uses thereof The present invention relates to antibodies, antibody fragments, conjugates of antibodies and antibody fragments with cytotoxic agents, and hybridomas producing the antibodies and antibody fragments, where the antibodies and antibody fragments recognize extracellula... | 04/10/2007 |
| 7163683 | Composition for inducing humoral anergy to an immunogen comprising a T cell epitope-deficient analog of the immunogen conjugated to a nonimmunogenic valency platform molecule Conjugates of nonimmunogenic valency platform molecules and analogs of immunogens that possess the specific B cell binding ability of the immunogen but lack T cell epitopes and which, when introduced into individuals, induce humoral anergy to the immunogen are discl... | 01/16/2007 |
| 7153499 | Vaccine immunotherapy for immune suppressed patients The present invention provides a formulation for inhibiting metastasis which includes 150–600 units of IL-2, a nonsteroidal anti-inflammatory drug (NSAID), and cyclophosphamide. The present invention further provides a formulation for inhibiting metastasis that in... | 12/26/2006 |
| 7129261 | Cytotoxic agents The present invention provides analogues of duocarmycins that are potent cytotoxins. Also provided are peptidyl and disulfide linkers that are cleaved in vivo. The linkers are of use in forming prodrugs and conjugates of the cytotoxins of the invention as well as ot... | 10/31/2006 |
| 7128913 | Erythropoietin conjugates The present invention refers to conjugates of erythropoietin with poly(ethylene glycol) comprising an erythropoietin glycoprotein having an N-terminal α-amino group and having the in vivo biological activity of causing bone marrow cells to increase production of re... | 10/31/2006 |
| 7128911 | Antigen arrays for treatment of bone disease The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising an ordered and repetitive antigen or antigenic determinant array, and in particular a RANKL protein, RANKL fragmen... | 10/31/2006 |
| 7128903 | Pharmaceutical preparations useful for treating tumors and lesions of the skin and the mucous membranes and methods and kits using same A pharmaceutical preparation useful for treating a skin or mucous membrane lesion is provided. The pharmaceutical preparation including, as active ingredients, a therapeutically effective amount of trichloroacetic acid and hydrochloric acid, or trichloroacetic acid ... | 10/31/2006 |
| 7115266 | Angiotensin peptide-carrier conjugates and uses thereof The present invention provides conjugates of peptide derivatives of the mammalian peptide hormones angiotensinogen, angiotensin I and angiotensin II, presented in a repetitive scaffold by coupling the peptide derivatives to a carrier, particularly a virus-like parti... | 10/03/2006 |
| 7105162 | Pharmaceutical composition for immunomodulation based on peptides and adjuvants Pharmaceutical composition containing at least one peptide or protein (fragment) with an immunomodulatory activity together with an adjuvant. The peptide is derived from a pathogenic agent or a tumour antigen. The adjuvant is capable of increasing the binding of the... | 09/12/2006 |
| 7094766 | Use of locally applied DNA fragments Methods of treatment or prevention of hyperproliferative diseases or pre-cancerous conditions affecting epithelial cells, such as psoriasis, vitiligo, atopic dermatitis, or hyperproliferative or UV-responsive dermatoses, hyperproliferative or allergically mediated d... | 08/22/2006 |
| 7087232 | Process for producing a culture of and product obtained thereby The present invention relates to the establishment of a cultivation condition that is suitable for the large-scale production of pharmacologically active filtrates from a culture of A. camphorata, in particular, by optimizing the agitation rate and/or pH valu... | 08/08/2006 |
| 7087600 | Peptidyl prodrugs and linkers and stabilizers useful therefor The present invention provides analogues of duocarmycins that are potent cytotoxins. Also provided are peptidyl and disulfide linkers that are cleaved in vivo. The linkers are of use in forming prodrugs and conjugates of the cytotoxins of the invention as well as ot... | 08/08/2006 |
| 7060685 | Compounds and methods for inhibiting selectin-mediated function Compounds and methods are provided for modulating in vitro and in vivo processes mediated by selectin binding. More specifically, selectin modulators and their use are described, wherein the selectin modulators that modulate (e.g., inhibit or enhance) a selectin-med... | 06/13/2006 |
| 7056512 | Method for down-regulating GDF-8 activity Disclosed are novel methods for increasing muscle mass by means of immunization against Growth Differentiation Factor 8 (GDF-8, myostatin). Immunization is preferably effected by administration of analogues of GDF-8 which are capable of inducing antibody production ... | 06/06/2006 |
| 7052913 | Matrices for drug delivery and methods for making and using the same In one aspect, biocompatible matrices such as sol-gels encapsulating a reaction center may be administered to a subject for conversion of prodrugs into biologically active agents. In certain embodiments, the biocompatible matrices of the present invention are sol-ge... | 05/30/2006 |
| 7038016 | Methods for purification of an activated PEG solution and for the synthesis of a modified hemoglobin solution The present invention employs a dissolved activated polyethylene glycol (aPEG) or related molecule that has been passed through a filtration means for the substantial reduction of bioburden or endotoxin levels in the aPEG solution. The resulting filtered aPEG soluti... | 05/02/2006 |
| 7037501 | Myostatin immnoconjugate A method to alter the phenotype of animals, e.g., avians, which employs passive and active immunization is provided. ... | 05/02/2006 |
| 7037295 | Co-extruded taper shaft An apparatus and method for providing a co-extruded, tapered multi-layer shaft. A co-extruded, tapered multi-layer shaft may be fabricated by selecting a first material for the inner layer of the shaft and a second material for the outer layer of the shaft. The firs... | 05/02/2006 |
| 7022521 | Methods and compositions for treating platelet-related disorders using MPL pathway inhibitory agents The invention relates to the treatment of subjects for the purpose inhibiting vaso-occlusive events, including thrombosis and embolism, by administering agents which reduce the number of circulating platelets to low or below normal levels. Methods and pharmaceutical... | 04/04/2006 |
| 7014856 | Ganglioside-KLH conjugate vaccines plus OS-21 This invention provides a vaccine for stimulating or enhancing in a subject to which the vaccine is administered, production of an antibody which recognizes a ganglioside, comprising an amount of ganglioside or oligosaccharide portion thereof conjugated to an immuno... | 03/21/2006 |
| 7001601 | Ganglioside-KLH conjugate vaccine plus QS-21 This invention provides a vaccine for stimulating or enhancing in a subject to which the vaccine is administered, production of an antibody which recognizes a ganglioside, comprising an amount of ganglioside or oligosaccharide portion thereof conjugated to an immuno... | 02/21/2006 |
