Bizarre Patents
Dining Table Having Integral Dishwasher
A space-saving dishwasher, which may be installed within a counter top or table, having a dish-carrying rack that is vertically shiftable through the open top of the dishwasher for facilitating loading and unloading of the dishes.
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| Number | Title | Issue Date |
| 8187607 | Hapten-carrier conjugates and uses thereof The present invention provides compositions comprising a conjugate of a hapten with a carrier in an ordered and repetitive array, and methods of making such compositions. The conjugates and compositions of the invention may comprise a variety of haptens, including h... | 05/29/2012 |
| 8178104 | Methods and compositions for targeting gC1qR/p32 Disclosed are compositions and methods useful for targeting gC1q/p32 receptors. The disclosed targeting is useful for delivering therapeutic and detectable agents to cancerous cells, and to areas of inflammation. ... | 05/15/2012 |
| 8163291 | Methods for generating stably linked complexes composed of homodimers, homotetramers or dimers of dimers and uses The present invention concerns methods and compositions for stably tethered structures of defined compositions, which may have multiple functionalities and/or binding specificities. Particular embodiments concern homodimers comprising monomers that contain a dimeriz... | 04/24/2012 |
| 8158129 | Dimeric alpha interferon PEGylated site-specifically shows enhanced and prolonged efficacy in vivo The present invention concerns methods and compositions for forming PEGylated complexes of defined stoichiometry and structure. In preferred embodiments, the PEGylated complex is formed using dock-and-lock technology, by attaching a therapeutic agent to a DDD sequen... | 04/17/2012 |
| 8124339 | Assays and methods using biomarkers Methods and assays examining expression of one or more biomarkers in a mammalian tissue or cell sample are provided. According to the disclosed methods and assays, detection of the expression of one or more such biomarkers is predictive or indicative that the tissue... | 02/28/2012 |
| 8110543 | Anti-invasive and anti-angiogenic compositions A peptide compound having the sequence Lys-Pro-Ser-Ser-Pro-Pro-Glu-Glu [SEQ ID NO:2] or a substitution variant, addition variant or other chemical derivative thereof inhibits cell invasion, endothelial tube formation or angiogenesis in vitro. A number of substitutio... | 02/07/2012 |
| 8105608 | Method of treatment using ligand-immunogen conjugates A method and pharmaceutical composition are provided for enhancing the endogenous immune response-mediated elimination of a population of pathogenic cells in a host animal wherein the pathogenic cells preferentially express, uniquely express, or overexpress a bindin... | 01/31/2012 |
| 8048425 | Cytotoxic ribonuclease variants This invention relates to cytotoxic variants of human ribonuclease 1 (RNase 1) identified through analysis of the interaction between RNase 1 and the human ribonuclease inhibitor (hRI) as defined by the three dimensional (3-D) atomic structure of the RNase1 hRI comp... | 11/01/2011 |
| 8034352 | Tetrameric cytokines with improved biological activity The present invention concerns methods and compositions for forming cytokine-antibody complexes using dock-and-lock technology. In preferred embodiments, the cytokine-MAb DNL complex comprises an IgG antibody attached to two AD (anchor domain) moieties and four cyto... | 10/11/2011 |
| 8003111 | Dimeric alpha interferon pegylated site-specifically shows enhanced and prolonged efficacy in vivo The present invention concerns methods and compositions for forming PEGylated complexes of defined stoichiometry and structure. In preferred embodiments, the PEGylated complex is formed using dock-and-lock technology, by attaching a therapeutic agent to a DDD sequen... | 08/23/2011 |
| 7998486 | Enhanced immunogenicity of tumor associated antigens by addition of alphaGal epitopes The invention relates to methods and compositions for causing the selective targeting and killing of tumor cells. The present invention describes prophylactic or therapeutic cancer vaccines based on purified TAA proteins or TAA-derived synthetic peptides altered by ... | 08/16/2011 |
| 7976846 | Stress protein compositions and methods for prevention and treatment of cancer and infectious disease Pharmaceutical compositions comprising a stress protein complex and related molecules encoding or cells presenting such a complex are provided. The stress protein complex comprises an hsp110 or grp170 polypeptide complexed with an immunogenic polypeptide. The immuno... | 07/12/2011 |
| 7951378 | Immunoadhesin comprising a chimeric ICAM-1 molecule produced in a plant The immunoadhesions of the present invention are useful in treating rhinovirus infections. The immunoadhesions contain a chimeric ICAM molecule and may optionally also contain J chain and secretory compounds. The chimeric ICAM molecule is a fusion protein that has a... | 05/31/2011 |
| 7947282 | Methods of treatment using vascular occlusion in combination therapies The present invention relates generally to methods and compositions for treating a disease or condition by administering a first therapeutic protocol comprising targeting and delivering solid-phase platelet-dependent vascular occlusion agents, and administering at l... | 05/24/2011 |
| 7883707 | Induction of antigen specific immunnologic tolerance Antigen specific immune tolerance is induced in a mammalian host by administration of a toleragen in combination with a regimen of immunosuppression. The methods optionally include a preceding conditioning period, where immunosuppressive agents are administered in t... | 02/08/2011 |
| 7879335 | Glycoconjugates, glycoamino acids, intermediates thereto, and uses thereof The present invention provides novel n-alkenyl glycosides and glycoconjugates, n-alkyl glycoamino acids, and methods for the synthesis thereof. In another aspect, the present invention provides novel clustered glycopeptides and methods for the synthesis thereof. In ... | 02/01/2011 |
| 7867499 | Methods of treating dementia by administering virus-like particles coupled to Aβ The present invention relates to novel uses of a construct consisting of virus-like particle (VLP) structure chemically coupled to a fragment of the Aβ-1-42 peptide and its pharmaceutically acceptable salts (hereinafter CONSTRUCT), in particular to dosage regimens,... | 01/11/2011 |
| 7854934 | Glycoconjugates, glycoamino acids, intermediates thereto, and uses thereof The present invention provides novel glycosides and glycoconjugates, glycoamino acids, and methods for the synthesis thereof. In another aspect, the present invention provides novel clustered glycopeptides and methods for the synthesis thereof. In still another aspe... | 12/21/2010 |
| 7850975 | Chemically programmable immunity The present invention is related to methods and compositions that are capable of immediately immunizing a human or animal against any molecule or compound. The present invention comprises an immunity linker molecule with at least two sites; (1) a first binding site ... | 12/14/2010 |
| 7824688 | Glucan-based vaccines Anti-glucan antibodies have been found to be protective against systemic fungal infection with C. albicans, but the protective efficacy can be inhibited by blocking antibodies. The invention provides an immunogenic composition comprising a glucan and a pharma... | 11/02/2010 |
| 7824687 | Clustered multi-antigenic carbohydrate constructs, methods for their preparation, and uses thereof The present invention provides novel clustered multi-antigenic constructs having the structure: and methods for the synthesis thereof. In still another aspect, the present invention provides methods... | 11/02/2010 |
| 7763254 | Human immunodeficiency virus integrase-LEDGF p75 isoform protein-protein interactions The present invention relates to protein-protein interactions involved in AIDS. More specifically, the present invention relates to complexes of polypeptides or polynucleotides encoding the polypeptides, fragments of the polypeptides, antibodies to the complexes, Se... | 07/27/2010 |
| 7740860 | Composition and method for preventing or treating a virus infection The present invention provides multiple antigenic agents compositions and the use thereof to prevent or treat viral infections. ... | 06/22/2010 |
| 7678378 | Compounds for intracellular delivery of therapeutic moieties to nerve cells A compound for delivering a non-cytotoxic therapeutic moiety into nerve cells, the compound having the general formula: B-L-TM where: B is a binding agent capable of selectively binding to a nerve cell surface r... | 03/16/2010 |
| 7618637 | Heat shock protein-based vaccines and immunotherapies The present invention relates to methods and compositions for inducing an immune response in a subject, wherein the subject is administered an effective amount of at least one heat shock protein in combination with one or more defined target antigens. These methods ... | 11/17/2009 |
| 7608269 | Compositions and methods for treating cancer by modulating HER-2 and EGF receptors An alternative HER-2/neu product, herstatin, consists of subdomains I and II from the ectodomain of p185HER-2 and a unique 79 amino acid C-terminus encoded by intron 8. Recombinant herstatin added to cells was found to bind to and inhibit p185HER-2. The effects of e... | 10/27/2009 |
| 7534441 | Immunogenic LHRH compositions and methods relating thereto The present invention relates generally to an immunogenic LHRH composition and more particularly to an immunogenic LHRH composition comprising a LHRH C-terminal fragment of at least five amino acids. The present invention is useful, inter alia, as a prophylactic and... | 05/19/2009 |
| 7527797 | 0139 conjugate vaccines The invention pertains to conjugates of the capsular polysaccharide of Vibrio cholerae O139, or a structurally and/or immunologically related oligo- or poly-saccharide, and a carrier. These conjugates are useful as pharmaceutical compositions and/or vaccines ... | 05/05/2009 |
| 7527798 | Composition and method for preventing or treating a virus infection The present invention provides multiple antigenic agents compositions and the use thereof to prevent or treat viral infections. ... | 05/05/2009 |
| 7452541 | Hapten-carrier conjugates and uses thereof The present invention provides compositions comprising a conjugate of a hapten with a carrier in an ordered and repetitive array, and methods of making such compositions. The conjugates and compositions of the invention may comprise a variety of haptens, including h... | 11/18/2008 |
| 7431928 | Identification of new CD8 epitopes from HIV-1 proteins The invention relates to the identification and the selection of CTL epitopes able to induce a protection against an HIV infection. More particularly, the invention is concerned with peptides and nucleic acid sequence coding for these peptides derived from HIV-1 pro... | 10/07/2008 |
| 7432253 | Phosphoepoxides, method for making same and uses The invention provides compounds comprising at least one phosphoepoxide group of the formula: where R1 is selected from among —CH3 and —CH2—CH3. Cat+... | 10/07/2008 |
| 7430476 | Method for identification of t-cell epitopes and use for preparing molecules with reduced immunogenicity This invention relates to a novel approach for identification of T-cell epitopes, that give rise to an immune reaction in a living host. By means of this novel method biological compounds can be generated which have a no or at least a reduced immunogenicity when exp... | 09/30/2008 |
| 7422746 | Chemically programmable immunity Methods and compositions for immediately immunizing an individual against any molecule or compound. The present invention comprises an immunity linker with at least two sites; (1) at least one first binding site that binds to an immune response component in an indiv... | 09/09/2008 |
| 7413738 | Releasable polymeric conjugates based on biodegradable linkers Activated polymeric bicine derivatives such as, as well as conjugates made therewith are disclosed. Methods of making and using the bicine derivatives are also disclosed. ... | 08/19/2008 |
| 7404957 | Modified IL-4 mutein receptor antagonists This invention relates to modified IL-4 mutein receptor antagonists comprising an IL-4 mutein receptor antagonist coupled to polyethylene glycol. Related formulations and dosages and methods of administration thereof for therapeutic purposes are also provided. These... | 07/29/2008 |
| 7405266 | Sterically hindered poly(ethylene glycol) alkanoic acids and derivatives thereof The invention provides a sterically hindered polymer that comprises a water-soluble and non-peptidic polymer backbone having at least one terminus covalently bonded to an alkanoic acid or alkanoic acid derivative, wherein the carbon adjacent to the carbonyl group of... | 07/29/2008 |
| 7399827 | Page-4, an x-linked gage-like gene expressed in normal and neoplastic prostate, testis and uterus, and uses therefor PAGE-4 is a gene preferentially expressed in normal male and female reproductive tissues, prostate, testis, fallopian tube, uterus and placenta, as well as in prostate cancer, testicular cancer and uterine cancer. This expression pattern makes it a target for diagno... | 07/15/2008 |
| 7396533 | Polypeptides and nucleic acids encoding same DNAs are provided, whose genes are induced at least by Wnt-1. Also provided are nucleic acid molecules encoding those polypeptides, as well as vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides ... | 07/08/2008 |
| 7393831 | Peptide compositions and their use against HCV The invention relates to novel peptide compositions. In particular, the invention relates to a peptide composition comprising at least two peptides which are selected from among the following peptides: a peptide A having at least the amino acid sequence of SEQ ID N | 07/01/2008 |
