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Patent No. 5970981

Mouthguard made at least partially from an edible candy

A mouthguard includes a U-shaped upper bite plate which removably fits over upper teeth of a person, with the entire upper bite plate being made from a soft, deformable and edible gummi candy.

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Class 424/191.1 - Disclosed amino acid sequence derived from parasitic organism (e.g., Dirofilaria, Eimeria, Trichinella, etc.)


Subclass of Class 424 - Drug, bio-affecting and body treating compositions
Definition: Subject matter wherein the disclosed amino acid sequence
No. of patents: 221
Last issue date: 03/05/2013


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NumberTitleIssue Date
6270767Trypanosoma cruzi antigen, gene encoding therefor and methods of detecting and treating chagas disease
The nucleotide sequence of Tc100, a gene encoding PTc100, a new Trypanosoma antigen, and the amino acid sequence of PTc100 are described. Tc100 and PTc100, or fragments thereof, modified or otherwise, can be used directly or indirectly for the detection o...
08/07/2001
6261569Retro-, inverso- and retro-inverso synthetic peptide analogues
Synthetic peptide antigen analogues of native peptide antigens with partial or complete retro, inverso or retro-inverso modifications are provided. When administered as an immunogen to an immunocompetent host the synthetic peptide antigen analogues induce...
07/17/2001
6254869Cryptopain vaccines, antibodies, proteins, peptides, DNA and RNA for prophylaxis, treatment and diagnosis and for detection of cryptosporidium species
Vaccines, antibodies, proteins, DNAs and RNAs for diagnosis, prophylaxis, treatment and detection of Cryptosporidium species or Cryptosporidium species infections. Cryptosporidium species antigen and DNAs and RNA encoding the Cryptosporidium antigen and f...
07/03/2001
6248329Parasitic helminth cuticlin nucleic acid molecules and uses thereof
The present invention relates to: parasitic helminth cuticlin proteins; parasitic helminth cuticlin nucleic acid molecules, including those that encode such cuticlin proteins; antibodies raised against such cuticlin proteins; and compounds that inhibit pa...
06/19/2001
6242585Mycobacterium tuberculosis specific DNA fragment
This invention relates to a Mycobacterium tuberculosis specific DNA fragment containing IS like and repetitive sequences, a method of production of such DNA fragment and the use of such DNA fragment, for example, to rapidly diagnose Mycobacterium tubercul...
06/05/2001
6235283DNA encoding a cell membrane glycoprotein of a tick gut
This invention relates to an antigen isolated from the cattle tick Boophilus microplus and to the gene coding for that antigen and to the protein product of that gene. The antigen when used in part or in entirety as an immunogen administered to cattle as ...
05/22/2001
6235282Vaccinal fluid water-in-oil emulsions containing a metabolizable oil
Injectable water-in-oil emulsion possessing immunity adjuvant activity and which can be used in man and animals as vaccine or an immunological medicament comprising an oily phase comprising an oil , an aqueous phase and at least one emulsifier, wherein th...
05/22/2001
6228601Polypeptides for diagnosing infection with trypanosoma cruzi
Polypeptides are disclosed that are useful for diagnosing American trypanosomiasis, or Chagas disease, a disease caused by the infectious agent Trypanosoma cruzi. The polypeptides have a sequence that corresponds to the amino acid sequence of at least one...
05/08/2001
6228372Compounds and methods for the detection and prevention of T. cruzi infection
Compounds and methods are provided for diagnosing Trypanosoma cruzi infection. The disclosed compounds are polypeptides, or antibodies thereto, that contain one or more epitopes of T. cruzi antigens. The compounds are useful in a variety of immunoassays f...
05/08/2001
6228649Double targeted gene replacement in unicellular diploid organisms
Homozygous gene replacement can be created in unicellular diploid organisms by individually targeting each allele of a gene with genetic constructs containing two different and independent selectable markers. Selection for both markers indicates replaceme...
05/08/2001
6207158Parasitic helminth macrophage migration inhibitory factor proteins, nucleic acid molecules, and uses thereof
The present invention relates to parasitic helminth macrophage migration inhibitory factor (MIF) proteins; to parasitic helminth MIF nucleic acid molecules, including those that encode such MIF proteins; to antibodies raised against such MIF proteins; and...
03/27/2001
6203801Coccidiosis polypeptide and vaccines
The present invention relates to hydrophilic Eimeria polypeptides, DNA-fragments encoding those peptides, recombinant DNA molecules comprising such DNA-fragments, live recombinant carriers comprising such DNA-fragments or recombinant DNA molecules and hos...
03/20/2001
6193971Dictyocaulus viviparus antigen for diagnosing lungworm infestation and for vaccination
An immunogenic protein (DV 18) isolated from lungworm Dictyocaulus viviparus including variants and fragments thereof, are described. DNA encoding such protein, methods of isolating and preparing such protein, antibodies against such protein, immunoassays...
02/27/2001
6187311Engineered acarid allergen and process for producing the same
The invention provides a method for producing a modified major mite allergen, obtained by altering a major allergen of house dust mites by gene engineering, which involve the steps of culturing prokaryotic or eukaryotic host cells transformed with a repli...
02/13/2001
6183976Compounds and methods for the diagnosis and treatment of B. microti infection
Compounds and methods for the diagnosis and treatment of B. microti infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a B. microti antigen and DNA sequences encoding such polypeptides. Anti...
02/06/2001
6168923Compositions and methods for use of IL-12 as an adjuvant
Improved vaccine compositions and methods of making same are provided, which vaccines are characterized by an antigen from a pathogen and an effective adjuvanting amount of Interleukin-12. These IL-12 adjuvanted vaccines are capable of increasing the vacc...
01/02/2001
6120770Plasmodium proteins useful for preparing vaccine compositions
The present invention relates to DNA segments encoding MAEBL, an erythrocyte binding protein of a Plasmodium parasite, to substantially pure MAEBL proteins and to recombinantly or synthetically produced MAEBL molecules. The MAEBL proteins can be utilized ...
09/19/2000
6114142Parasitic helminth nucleic acid molecules/and uses thereof
The present invention relates to parasitic helminth proteins of about 39 kD (i.e., P39 proteins); to parasitic helminth P39 nucleic acid molecules, including those that encode such proteins; and to antibodies raised against such proteins. The present inve...
09/05/2000
6099843Parasitic helminth PLA2 proteins
The present invention relates to parasitic helminth PLA2 proteins; to parasitic helminth PLA2 nucleic acid molecules, including those that encode such proteins; to antibodies raised against such proteins; and to compounds that inhibit parasitic helminth p...
08/08/2000
6071518GP900 glycoprotein and fragments for treatment and detection/diagnosis of cryptosporidium
Peptides, polypeptides, glycoproteins, their functional mutants, variants, analogs, and fragments useful for treatment and detection/diagnosis of Cryptosporidium infections by competitive inhibition of the function of a Cryptosporidium protein/glycoprotei...
06/06/2000
6063902Ectoparasite histamine releasing factor, genes and uses thereof
The present invention relates to ectoparasite histamine releasing factor (HRF) proteins; to ectoparasite HRF nucleic acid molecules, including those that encode such HRF proteins; to antibodies raised against such HRF proteins; and to compounds that inhib...
05/16/2000
6060281Parasitic helminth PLA2 proteins and nucleic acid molecules
The present invention relates to parasitic helminth PLA2 proteins; to parasitic helminth PLA2 nucleic acid molecules, including those that encode such proteins; to antibodies raised against such proteins; and to compounds that inhibit parasitic helminth p...
05/09/2000
6054135Compounds and methods for the detection and prevention of T. cruzi infection
Compounds and methods are provided for diagnosing Trypanosoma cruzi infection. The disclosed compounds are polypeptides, or antibodies thereto, that contain one or more epitopes of T. cruzi antigens. The compounds are useful in a variety of immunoassays f...
04/25/2000
6022546Toxoplasma gondii antigens, the preparation thereof and the use thereof
The present invention relates to the identification of Toxoplasma gondii antigens and the preparation thereof by genetic engineering. A cDNA expression gene bank of this parasite was prepared. Recombinant clones which are of diagnostic interest were ident...
02/08/2000
6019974SPE-4 peptides
This application discloses SPE-4 related peptides, peptide-carrier protein conjugates and fusion proteins, immunogenic compositions, antibodies and methods for characterizing the SPE-4 related protein profiles, useful in diagnosing or monitoring SPE-4 rel...
02/01/2000
6017538Plasmodium falciparum antigens inducing protective antibodies
A molecule, protein or peptide characterized in that it is recognized by cytophilic antibodies from individuals who are immune to infection by Plasmodia, and recognized by non-cytophilic antibodies from individuals who are vulnerable to infection by Plasm...
01/25/2000
6015882Vaccines, antibodies, proteins, glycoproteins, DNAs and RNAs for prophylaxis and treatment of Cryptosporidium parvum infections
Vaccines, antibodies, proteins, glycoproteins, DNAs and RNAs useful for passive or active prophylaxis and treatment of Cryptosporidium infections. Cryptosporidium antigen comprised of a protein with or without carbohydrates attached thereto. Polyclonal an...
01/18/2000
6001363Coccidiosis poultry vaccine
This invention relates to a novel Eimeria protein with immunogenic properties as well as to DNA sequences encoding these proteins. This protein can be administered to poultry thereby protecting the birds against coccidiosis. In addition the DNA encoding t...
12/14/1999
5985264IL-12 Stimulation of Neonatal immunity
The present invention relates to a method of inducing a Th1-like response against a pathogen in a neonatal host, which comprises administering to the neonatal host an effective amount of IL-12 and an antigen of the pathogen. Also encompassed by the presen...
11/16/1999
5977306Parasitic helminth P39 proteins, and uses thereof
The present invention relates to parasitic helminth proteins of about 39 kD (i.e., P39 proteins); to parasitic helminth P39 nucleic acid molecules, including those that encode such proteins; and to antibodies raised against such proteins. The present inve...
11/02/1999
5972351Plasmodium falciparum MHC class I-restricted CTL epitopes derived from pre-erythrocytic stage antigens
A method of identifying peptides of an antigen of interest which are capable of recognition by or induction of cytotoxic T lymphocytes, comprises the steps of: ascertaining a "motif" of peptides which bind to a chosen HLA class I allele; providing peptide...
10/26/1999
5961979Stress protein-peptide complexes as prophylactic and therapeutic vaccines against intracellular pathogens
Disclosed is a family of vaccines that contain stress protein-peptide complexes which when administered to a mammal are operative at initiating in the mammal cytotoxic T cell responses against preselected intracellular pathogens. Also disclosed are method...
10/05/1999
5942413Nematode vaccine
Disclosed is a substantially purified antigen derived from a first species of parasitic nematodes, which antigen is capable of providing protection to a host from parasitism infestation by a second nematode species, which may be the same as or different f...
08/24/1999
5932225Vaccine comprising eimeria spp. gametocyte antigen
Substantially purified Eimeria maxima gametocytes have been prepared and methods for their preparations are disclosed. A proteinaceous extract derived from the gametocytes comprises at least nine proteins of varying molecular weights. Vaccines for conferr...
08/03/1999
5874527Plasmodium vivax blood stage antigens
This invention is directed to novel species-specific P. vivax malarial peptide antigens which are proteins or fragments of proteins secreted into the plasma of a susceptible mammalian host after infection, and to monoclonal or polyclonal antibodies direct...
02/23/1999
5871738Nematode vaccine
Disclosed is a substantially purified antigen derived from a first parasitic nematode species which, when administered to a host animal, is capable of protecting the host animal from infestation by a second parasitic nematode species, wherein the first an...
02/16/1999
5861160Isospora suis sporozoite antigen
Isospora suis is propagated using a swine testicular cell line which facilitates production of sporozoites and merozoites, either or both of which can be used in a vaccine for swine. Antibodies against Isospora suis sporozoites, which inhibit the infectiv...
01/19/1999
5851535Mimotopic polypeptides of Toxoplasma gondii and applications
The invention relates to a polypeptide capable of reacting specifically with an anti-Toxoplasma gondii P30 protein antibody, and comprising a peptide sequence, in which any succession of 6 contiguous amino acids exhibits at most 67% homology with the pept...
12/22/1998
5846527Continuous cell line and vaccine against avian coccidia
A non-lymphoid continuous cell line adapted for propagation of avian coccidia is provided. This cell line is useful for the production of vaccine antigenes for prophylactic treatment of poultry, particularly in a novel vaccine for coccidia....
12/08/1998
5843722Coccidiosis poultry vaccine
This invention relates to novel Eimeria proteins with immunogenic properties as well as to DNA sequences encoding these proteins. These proteins can be administered to poultry thereby protecting the birds against coccidiosis. In addition the DNA encoding ...
12/01/1998
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