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Pizza Pie With Concentric Rings of Crust
A pizza mold for forming a plurality of concentric raised ridges of dough (i.e., crust) on the surface of a pizza pie.
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| Number | Title | Issue Date |
| 8182819 | Composition and method for facilitating the internalization of a therapeutic agent into a cell The present invention is a composition and method for facilitating the internalization of a therapeutic agent into a cell. Specifically, the invention relates to the use of the extracellular domain of basigin-2, cyclophilin, or anti-basigin-2 antibody or antibody fr... | 05/22/2012 |
| 8178102 | Emulsified composition for dilution and cancer vaccine composition Provided is an emulsified composition for diluting a cancer antigen peptide or a dimer thereof. Also provided is a novel cancer vaccine composition or specific CTL inducer that efficiently induces CTL irrespective of the type of cancer antigen peptide when mixing th... | 05/15/2012 |
| 8168189 | Protein A compositions and methods of use Methods and compositions for modulating an immune response in a subject are provided. Methods include administering to the subject a composition comprising an effective amount of a lymphocyte differentiation factor, e.g., protein A (PA), sufficient to modulate the i... | 05/01/2012 |
| 8163289 | Methods and compositions involving polymeric immunoglobulin fusion proteins The present invention concerns inventive polypeptides. The present invention also concerns compositions and vaccines comprising the inventive polypeptides. In other embodiments of the invention, the inventive polypeptides are provided to a subject, used to vaccinate... | 04/24/2012 |
| 8163290 | Glycolipids and analogues thereof as antigens for NKT cells This invention relates to immunogenic compounds which serve as ligands for NKT (natural killer T) cells and to methods of use thereof in modulating immune responses. ... | 04/24/2012 |
| 8158592 | Immunostimulatory nucleic acid molecules Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2 response to a Th1 response in a subject are disclosed. Methods for treating atopic diseases, including atop... | 04/17/2012 |
| 8153136 | Yeast-based vaccines as immunotherapy Compositions and methods for treating and/or preventing a variety of diseases and conditions that are amenable to immunotherapy and, in one particular embodiment, compositions and methods for treating and/or preventing cancer in an animal are described. Specifically... | 04/10/2012 |
| 8142785 | Method or use of a solubilized glucan product to increase immunostimulation in animals β-(1-6)-Glucanase treatment of glucan from yeast cells, pure or feed grade especially yeast from the family Saccharomyces and particularly Saccharomyces cerevisiae, provides a novel glucan product suitable for use in enhancing the stimulation of host ... | 03/27/2012 |
| 8129345 | MUC1-IκB kinase complexes and their activities The disclosure provides methods of identifying and making compounds and pharmaceutical compositions containing the compounds that inhibit the interaction between MUC1 and an IKK. The disclosure also provides in vivo and in vitro methods of inhibiting such an interac... | 03/06/2012 |
| 8124590 | Biodegradable immunomodulatory formulations and methods for use thereof The invention provides new compositions and methods for immunomodulation of individuals. Immunomodulation is accomplished by administration of immunomodulatory polynucleotide/microcarrier (IMP/MC) complexes. The IMP/MC complexes may be covalently or non-covalently b... | 02/28/2012 |
| 8124096 | Immune response modifier compositions and methods A pharmaceutical composition comprising 1-(2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine that is stable to sterilization and suitable for topical application directly to tissue sites where the dermis has been breached, and has been sterilized, packaged compositi... | 02/28/2012 |
| 8114405 | Cancer vaccine based on brother of regulator of imprinted sites molecule (BORIS) Polynucleotides encoding a nonfunctional mutant form of the Brother of Regulator of Imprinted Sites (BORIS) molecule, nonfunctional mutated BORIS protein, polypeptide or peptide and modified protein forms of BORIS are described. These molecules are used as a therape... | 02/14/2012 |
| 8114406 | Peptides and their utility in modulation of behavior of cells expressing α3β1 integrins The present invention relates to a peptide comprising the sequence R1—X1—X2—X3—X4—R2, wherein X1 is selected from the group consisting of N, Q, D and S; X2 is selected ... | 02/14/2012 |
| 8114848 | Immunomodulatory oligonucleotides Oligonucleotides containing unthylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response in a subject are disclosed. Also disclosed are therapies for treating diseases associated with immune system activation that are... | 02/14/2012 |
| 8114404 | Method and composition for altering a B cell mediated pathology The present invention provides a method for altering a B cell mediated pathology in a patient. This method comprises administering a composition comprising at least one and/or two chimeric proteins. Each chimeric protein comprises at least a portion of either the V | 02/14/2012 |
| 8105601 | Compositions and methods for modulating an immune response The present invention provides a composition for suppressing an inflammatory immune response comprising the excretory/secretory (ES) component of Fasciola hepatica or a fraction thereof. The composition has particular utility in the treatment or prophylaxis o... | 01/31/2012 |
| 8097587 | IGF-I protein variants for treating IGFBP-1-related disorders IGF-I variants having an alanine, glycine, or serine amino acid residue at position 16, 25, 49 or at positions 3 and 49 of native-sequence IGF-I are provided that are useful to treat a disorder characterized by dysregulation of the GH/IGF axis in a mammal, such as a... | 01/17/2012 |
| 8097256 | Cancer vaccines and vaccination methods Methods and compositions for treating cancers (e.g., neural cancers) by dendritic cell vaccination are provided herein. ... | 01/17/2012 |
| 8092805 | Dual inhibitors of HIV-1 gp-120 interactions Compounds, which inhibit the binding of gp120 to CD4 as well as 17b and methods for their use in inhibiting the HIV fusion process, are provided. ... | 01/10/2012 |
| 8084439 | Methods for identifying compounds for the treatment of type 1 diabetes The present invention provides methods of identifying candidate compounds for the treatment of type I diabetes and also provides methods for treating patients with type I diabetes and for limiting pancreatic beta cell apoptosis. The present invention also provides m... | 12/27/2011 |
| 8075895 | Identification of antigenic peptides from multiple myeloma cells Multiple myeloma (MM) is a clonal B cell malignancy and remains essentially incurable by conventional anti-tumor therapy. Patients with MM have a median survival of only three years. MM is characterized by proliferation and accumulation of mature plasma cells in the... | 12/13/2011 |
| 8075896 | Method to enhance an immune response of nucleic acid vaccination A composition comprising liposomes associated with a nucleic acid operatively encoding an antigenic protein and with an assistor protein, wherein the assistor protein shares at least one epitope with the antigenic protein, and wherein the nucleic acid and said assis... | 12/13/2011 |
| 8075894 | Use of soluble CD164 in inflammatory and/or autoimmune disorders The present invention relates to novel therapeutic uses of soluble proteins comprising the extracellular region of human CD164, in particular for treating inflammatory and/or autoimmune disorders. ... | 12/13/2011 |
| 8062641 | Immunogens for meningitidis-A vaccines An oligosaccharide useful for a Meningitidis A vaccine contains a first mannose unit having a spacer in the alpha configuration at C-1, which spacer is capable of conjugating to a protein, and which is connected to a second mannose unit through a 1,6-linkage which c... | 11/22/2011 |
| 8057799 | ErbB interface peptidomimetics and methods of use thereof Peptides, mimetics and antibodies of erbB, TNF, and IgSF receptors and pharmaceutical compositions comprising the same are described. Methods of using such antibodies, peptides, and mimetics in therapeutic, prophylactic, imaging and diagnostic applications are discl... | 11/15/2011 |
| 8048423 | Botulinum toxin therapy for skin disorders Methods for treating skin disorders by local administration of a Clostridial toxin, such as a botulinum toxin, to a patient with a skin disorder. ... | 11/01/2011 |
| 8043622 | Method of treating inflammatory lung disease with suppressors of CpG oligonucleotides The present disclosure relates to oligodeoxynucleotides that suppress an immune response. Methods are disclosed for inhibiting or treating inflammatory lung disease by administering a therapeutically effective amount of a suppressive oligodeoxynucleotide. ... | 10/25/2011 |
| 8030285 | Oligodeoxynucleotide and its use to induce an immune response The present invention provides a substantially pure or isolated oligodeoxynucleotide of at least about 10 nucleotides comprising a sequence represented by either the formula: 5′N1N2N3T-CpG-WN4N5N | 10/04/2011 |
| 8030288 | Methods for identifying compounds for the treatment of type 1 diabetes The present invention provides methods of identifying candidate compounds for the treatment of type I diabetes comprising contacting pancreatic β cells with an amount of apolipoprotein CIII (“apoCIII”) effective to increase intracellular calcium concentration, ... | 10/04/2011 |
| 8021664 | Tumor antigens Bfa5 for prevention and/or treatment of cancer The present invention relates to a nucleic acid encoding a polypeptide and the use of the nucleic acid or polypeptide in preventing and/or treating cancer. In particular, the invention relates to improved vectors for the insertion and expression of foreign genes enc... | 09/20/2011 |
| 8021665 | Identification and application of antibiotic synergy The present invention provides a pharmaceutical composition useful for treating bacterial infections in humans and animals which comprises administering to a human or animal in need thereof, an antibacterially effective combination of a β-lactam antibiotic and an i... | 09/20/2011 |
| 8017590 | Method of inducing and/or enhancing an immune response to tumor antigens An improved method of inducing and/or enhancing an immune response to a tumor antigen is disclosed. The method involves administering the tumor antigen, nucleic acid coding therefor, vectors and/or cells comprising said nucleic acid, or vaccines comprising the afore... | 09/13/2011 |
| 8012486 | Composition for treating atopic dermatitis comprising hirsutenone as an active ingredient The present invention relates to a composition for treating atopic dermatitis comprising hirsutenone as an active ingredient. Hirsutenone as the active ingredient of the present composition decreases the number of eosinophil and the level of IgE increased in atopic ... | 09/06/2011 |
| 8007808 | Composition and method for facilitating the internalization of a therapeutic agent into a cell The present invention is a composition and method for facilitating the internalization of a therapeutic agent into a cell. Specifically, the invention relates to the use of the extracellular domain of basigin-2, cyclophilin, or anti-basigin-2 antibody or antibody fr... | 08/30/2011 |
| 8007807 | Multiple vaccination including serogroup C meningococcus Various improvements to vaccines that include a serogroup C meningococcal conjugate antigen, including: (a) co-administration with acellular B. pertussis antigen; (b) co-administration with an inactivated poliovirus antigen; (c) supply in a kit together with ... | 08/30/2011 |
| 8007806 | Vaccine composition comprising a fibronectin binding protein or a fibronectin binding peptide The present invention relates to a composition comprising at least one fibronectin binding protein, and/or at least one a truncated fibronectin binding protein and/or at least one fibronectin binding peptide, all comprising at least one fibronectin binding domain; a... | 08/30/2011 |
| 7998483 | Lage-1 tumor associated nucleic acids The invention describes the LAGE-1 tumor associated gene, including fragments, allelic variants and splice variants thereof. Also included are polypeptides and fragments thereof encoded by such genes, and antibodies relating thereto. Methods and products also are pr... | 08/16/2011 |
| 7968096 | Methods and compositions for treating This invention relates to a method for treatment of latent Toxoplasma gondii infection. The invention provides for the use of Hsp90 inhibitors for treatment of latent Toxoplasma gondii infection, particularly in an immunocompromised subject. Also provi... | 06/28/2011 |
| 7960356 | Oligodeoxynucleotide and its use to induce an immune response D type CpG oligodeoxynucleotides are provided herein that include a sequence represented by the following formula: 5′ X1X2X3Pu1 Py2 CpG Pu3 Py4 X4X5X6... | 06/14/2011 |
| 7955600 | Attenuated salmonella SP12 mutants as antigen carriers The present invention relates to vaccines, in particular, to an attenuated gram-negative cell comprising the SPI2 gene locus, wherein at least one gene of the SPI2 locus is inactivated, wherein said inactivation results in an attenuation/reduction of virulence compa... | 06/07/2011 |
