...that in 1800 ether was first used by partyers as a fun diversion? Sniffing the gas led to hilarious and raucous laughter as people watched each other become more and more intoxicated and silly. Several doctors independently realized the value ether would have to anesthetize surgery patients. Of those who claimed rights to the "discovery," none had a happy ending. One had a seizure and died defending his rights. Another spent his life in an asylum because he had been denied acclaim. A third became addicted to chloroform and, in a New York City jail, he soaked a cloth in the drug, severed an artery and bled to death.
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| Number | Title | Issue Date |
| 7247441 | Nucleic acid sequence and protein in addition to polypeptides coding for mannitol dehydrogenases or parts thereof and the production and use thereof in diagnosis and therapy The invention relates to polypeptides made of mannitol-dehydrogenase of Cladosporium herbarum and Alternaria alternata nucleic acids coding therefor and the use thereof in diagnosis and therapy. ... | 07/24/2007 |
| 7168933 | Device for discharge or outfeed of a pasty product, preferably foodstuff, from a container The present invention relates to a device for discharge or outfeed of a pasty product, preferably foodstuff, from a container. A piston means (11) is brought to perform a discharge movement in a discharge direction (F) for discharge or outfeed of the product ... | 01/30/2007 |
| 7087425 | Method of purifying oocysts using enzymatic digestion of fecal debris The invention provides methods and compositions for purifying protozoan oocysts. In particular embodiments, the oocysts are Eimeria oocysts. The methods comprise contacting a composition comprising fecal material and protozoan oocysts with polysaccharidase un... | 08/08/2006 |
| 6914129 | Anti-IgE antibodies The present invention describes IgE antagonists (including variant anti-IgE antibodies) and their use in diagnosis, therapy or prophylaxis of allergic and other IgE-mediated disorders, including asthma, food allergies, hypersensitivity and anaphylactic reactions. | 07/05/2005 |
| 6849259 | Polyclonal antibody composition for treating allergy A pharmaceutical composition for treating allergy is described. The composition comprises as an active ingredient a recombinant polyclonal antibody or a mixture of different monoclonal antibodies capable of reacting with or binding to an allergen together with one o... | 02/01/2005 |
| 6639054 | Preparation of deallergenized proteins and permuteins Modified proteins are disclosed that maintain enzymatic and insecticidal activity while displaying reduced or eliminated allergenicity. Epitopes which bind to anti-patatin antibodies were identified, and removed via site directed mutagenesis. Tyrosines we... | 10/28/2003 |
| 6558961 | Immunodiagnostics using particle delivery methods Methods for assessing immunocompetence, cellular or humoral immunity, antigen exposure, or allergic conditions in an individual by accelerating diagnostic particles into a target skin site in the individual are provided.... | 05/06/2003 |
| 6200565 | Oral administration of immunoglobulins for treating autoimmune hearing loss The present invention is directed to methods of treating autoimmune sensorineural hearing loss in a patient by orally administering a human immunoglobulin preparation to the patient.... | 03/13/2001 |
| 5968526 | T cell epitopes of the major allergens from Dermatophagoides (house dust mite) The present invention provides isolated peptides of the major protein allergens of the genus Dermatophagoides. Peptides within the scope of the invention comprises at least one T cell epitope, or preferably at least two T cell epitopes of a protein allerg... | 10/19/1999 |
| 5871734 | Treatment for asthma with VLA-4 blocking agents A method for the treatment of asthma is disclosed. The method comprises administration of an antibody, polypeptide or other molecule recognizing VLA-4, a protein expressed on the surface of certain leukocytes such as eosinophils.... | 02/16/1999 |
| 5643572 | Methods and compositions for the modulation of host immune response to an allergen The present invention provides novel compositions and methods useful in the, modulation or selective suppression of host immune responses to an immunogen of interest, particularly exogenous antigens and allergens such as urushiol, the active plant compone... | 07/01/1997 |
| 5512283 | Methods for the selective suppression of an immune response to dust mite der Pi The present invention provides novel compositions and methods useful in the modulation or selective suppression of host immune responses to an immunogen of interest, particularly to immunogens which are exogenous antigens or allergens. Subject composition... | 04/30/1996 |
| 5026545 | Treatment of allergy and composition therefor A pharmaceutical composition comprises an immune complex of an allergen and a purified antibody specific thereto, the allergen being selected from a specific subclass of antigen which causes immediate hypersensitivity that is mediated by IgE antibody, and... | 06/25/1991 |
| 4740371 | Treatment of allergy In the treatment of allergy, desensitization is effected by administering the allergen in admixture with an antibody thereto, the antibody being present in a molar excess. The antibody is preferably one raised in the patient.... | 04/26/1988 |