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Class 424/163.1 - Binds antigens of multiple bacterial species (e.g., multivalent antiserum that binds antigens of multiple bacterial species, etc.)


Subclass of Class 424 - Drug, bio-affecting and body treating compositions
Definition: Subject matter involving an antiserum or other combination
No. of patents: 45
Last issue date: 12/06/2011


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NumberTitleIssue Date
8071102Methods to clear meningitis causing agents using antibodies to peptides representing epitopic sites for bacterial and viral meningitis causing agents
Novel vaccines include polypeptides that comprise regions corresponding to a chemokine and a hapten. The hapten can be an amino acid sequence corresponding to the Meningitis Related Homologous Antigenic Sequences (MRHAS) of bacterial and viral agents known to cause ...
12/06/2011
7235644Vaccine against Gram-negative bacterial infections
A vaccine, effective in inducing the production of antibodies with which to immunize a second subject passively against infection by Gram-negative bacteria and LPS-mediated pathology, comprises a non-covalent polyvalent complex formed between purified, detoxified LP...
06/26/2007
7195763Surface proteins from gram-positive bacteria having highly conserved motifs and antibodies that recognize them
Isolated peptide sequences and proteins containing these sequences are provided which are useful in the prevention and treatment of infection caused by Gram-positive bacteria. The peptide sequences have been shown to be highly conserved motifs in the surface protein...
03/27/2007
7025963Vaccine against Gram-negative bacterial infections
A vaccine, effective in inducing the production of antibodies with which to immunize a second subject passively against infection by Gram-negative bacteria and LPS-mediated pathology, comprises a non-covalent polyvalent complex formed between purified, detoxified LP...
04/11/2006
6994854Protective epitopes of adenyl cyclase-haemolysin (AC-Hly), their application to the treatment or to the prevention of bordetella infections
The subject of the invention is amino acid sequences of the AC-Hly from B. pertussis, B. parapertussis and/or B. bronchiseptica, carrying epitopes capable of inducing a protective immune response against infection by Bordetella. The subject of t...
02/07/2006
6979550Method for diagnosis of, and determination of susceptibility to bovine mastitis
The present invention discloses a method for detection and prediction of mastitis. The method comprises the steps of determining the values of mastitis indicators and comparing the values with predetermined standards, wherein deviation from the standards provides a ...
12/27/2005
6936247Filariid anti-P22U antibodies
The present invention relates to isolated parasitic helminth nucleic acid sequences capable of hybridizing, under stringent conditions, to at least a portion of D. immitis nucleic acid sequence p4 and/or to at least a portion of D. immitis nucleic acid...
08/30/2005
6887481Bacterial-derived molecules and therapeutic and diagnostic uses therefor
The present invention relates generally to molecules derived from a Mycobacterium species and recombinant, synthetic, derivative, homologue and analogue forms of said molecules. The molecules of the present invention are useful in diagnostic assays for Myc...
05/03/2005
6881410Treatment of E. faecium infection
The present invention provides bacterial and fungal ABC transporter proteins, immunogenic fragments thereof, neutralising agents specific thereto and binding agents specific thereto for therapeutic and diagnostic use, together with diagnostic test methods, methods o...
04/19/2005
6803035Anti-diarrheal and method for using the same
A food product and method for treating and preventing diarrhea in a subject animal suffering from or susceptible to diarrhea. The method comprises administering an egg product to the subject animal wherein the egg product is obtained from a hyperimmunized avian....
10/12/2004
6790661System for detecting bacteria in blood, blood products, and fluids of tissues
The invention provides methods for screening for the presence of a clinically relevant amount of bacteria in donor blood or a blood product from a donor mammal, particularly blood or a blood product that will be transferred from the donor mammal to a recipient mamma...
09/14/2004
6743430Multicomponent vaccine containing clostridial and non-clostridial organisms in a low dose
Disclosed herein is a multicomponent low dose vaccine comprising a safe and immunogenically effective combination of a protective antigen component or components of clostridial organism, a protective antigen component of a non-clostridial organism and an adjuvant.
06/01/2004
6733983Method for identifying a mycobacterium species
The invention relates to a method for identifying a Mycobacterium species comprising the steps of: a) contacting at least one immuno-cross reactive antigen component of a mycobacterial species with a sample of a body fluid of a human or animal individual;...
05/11/2004
6713059Antibodies raised against immunogenic conjugates of gram-negative bacterial autoinducer molecules
The present invention relates to an immunogenic conjugate comprising a carrier molecule coupled to an autoinducer of a Gram negative bacteria. The immunogenic conjugate, when combined with a pharmaceutically acceptable carrier, forms a suitable vaccine for mammals t...
03/30/2004
6623737Antibodies to intimin-like proteins of E. coli
The invention is related to antibodies, particularly monoclonal antibodies, which recognize particularly epitopes of the intimin protein of enteropathogenic E. coli and enterohemorrhagic E. coli, methods of detecting such E. coli by use of these antibodie...
09/23/2003
6582925Desaturase antigen of mycobacterium tuberculosis
The use of genetic methodology based on the fusion of the proteins with the alcaline phosphatase (Lim et al., 1995) has allowed the isolation of a new exported protein of M. tuberculosis. In the present article, first of all the isolation of a gene encodi...
06/24/2003
6544516Treatment and diagnosis of infections of gram positive cocci
The present invention provides bacterial and fungal ABC transporter proteins, immunogenic fragments thereof, neutralizing agents specific thereto and binding agents specific thereto for therapeutic and diagnostic use, together with diagnostic test methods...
04/08/2003
6495334Recombinant Sef14 fimbrial protein from Salmonella
A truncated SE fimbria antigen useful as an antigen for immunoassay diagnosis of Salmonella enteritidis (SE) infection or evidence of infection....
12/17/2002
6416962Method and device for identifying a mycobacterium species responsible for a mycobacterial infection
The invention relates to a method for identifying a Mycobacterium species responsible for a mycobacterial infection in human or animal, comprising selecting a suitable mycobacterial species and strain; preparing at least one mycobacterial antigen, respect...
07/09/2002
6383763Detection of mycobacteria
The present invention is directed to methods and compositions for the detection of infection and disease due to members of the genus Mycobacterium. In particular, the present invention is well-suited to the detection and identification of patients with di...
05/07/2002
6376203Glycoglycerophospholipid, antibody thereagainst, and method for detecting mycoplasma
Mouse is immunized with an antigen of a lipid fraction originating from Mycoplasma fermentans. Its spleen cells are fused with mouse myeloma cells to prepare hybridomas. A hybridoma is selected, which produces a monoclonal antibody having reaction specifi...
04/23/2002
6365156Method for improving the half-life of soluble viral-specific ligands on mucosal membranes
This invention relates to methods of increasing the half-life of a viral-specific ligand on a mucosal membrane by modifying the viral-specific ligand to bind the bacteria colonized on the mucosal membrane. The invention also provides a chimeric molecule c...
04/02/2002
6350449Antibodies to meningococcal polysaccharide conjugate vaccines
The invention relates to chemically-modified group B polysaccharides of Neisseria meningitidis. The invention also provides vaccines in which the respective modified polysaccharides are conjugated to a protein carrier, and the like, as well as antibodies ...
02/26/2002
6258359Immunogenic compositions against helicobacter infection, polypeptides for use in the compositions, and nucleic acid sequences encoding said polypeptides
There is provided an immunogenic composition capable of inducing protective antibodies against Helicobacter infection characterized in that it comprises: i) at least one sub-unit of a urease structural polypeptide from Helicobacter pylori (SEQ ID NO: 22,2...
07/10/2001
6096310Oral immunotherapy of bacterial overgrowth
The object of the present invention is the oral administration of animal immunoglobulins for the treatment of gastrointestinal disorders caused by bacterial and/or yeast overgrowth. Immunoglobulins derived from the blood, plasma or serum of animals, such ...
08/01/2000
5817473Method and device for identifying a mycobacterium species responsible for a mycobacterial infection
A method for identifying a Mycobacterium species responsible for a mycobacterial infection in human or animal, comprising selecting a suitable mycobacterial species and strain; preparing at least one mycobacterial antigen, respectively antigen preparation...
10/06/1998
5741489Passively administered antibody that enhances feed conversion efficiency
A method for increasing feed conversion efficiency in mammals, such as swine, wherein the mammal is fed a diet containing an antibody produced using the enzyme urease as the antigen....
04/21/1998
5718899Method and compositions for direct concentrated delivery of passive immunity
Compositions containing a high concentration of the full repertoire of immunoglobulins, including IgA, IgM and IgG, are used to combat infections from microorganisms and viruses at a wound, surgical, or burn site, or normal tissue at times of risk of infe...
02/17/1998
5716793Method for diagnosing a patient for chlamydia
A method of detecting chlamydia in a extracellular sample is provided which comprises contacting the sample with an idiotypic antibody to GLXA to form an immunocomplex and detecting the immunocomplex....
02/10/1998
5707627Methods and compositions for the direct concentrated delivery of passive immunity
Compositions containing a high concentration of the full repertoire of immunoglobulins, including IgA, IgM and IgG, are used to combat infections from microorganisms and viruses at a wound, surgical, or burn site, or normal tissue at times of risk of infe...
01/13/1998
5700465Bovine serum and bovine IgG as preventives and therapeutives for bovine mastitis
Immunoglobulin G-2 (IgG2), e g. bovine IgG2, and its reaction with neutrophils can be used to enhance the neutrophil's functional status in host animal defense against bacterial infections....
12/23/1997
5681565Methods and compositions for passive immunotherapy
The direct, concentrated local delivery of antibodies, and pooled human immunoglobulins in particular, to tissue surfaces (e.g., wounds, burns, etc.), and biomaterial implant surfaces significantly decreases the rate of infection at those sites and enhanc...
10/28/1997
5612031Antibodies against streptococcus
Antibodies which bind the surface antigen I/II of Streptococcus sobrinus serotype d and cross react with the surface antigen I/II of Streptococcus mutans serotypes c, e, f and g and method to combat dental caries by applying the antibodies which bind the ...
03/18/1997
5585098Oral administration of chicken yolk immunoglobulins to lower somatic cell count in the milk of lactating ruminants
A method for lowering somatic cell count in the milk of a lactating ruminant is disclosed. IgY antibodies are first obtained from the egg of a hen which has been actively immunized against one or more mastitis-causing pathogenic organisms by injection wit...
12/17/1996
5518721Antibodies against Streptococcus
Monoclonal antibodies which bind the surface antigen I/II of Streptococcus sobrinus serotype d and cross react with the surface antigen I/II of Streptococcus mutans serotypes c, e, f and g and method for producing the antibody. Compositions comprising the...
05/21/1996
5505945Method and compositions for the direct concentrated delivery of passive immunity
Compositions containing a high concentration of the full repertoire of immunoglobulins, including IgA, IgM and IgG, are used to combat infections from microorganisms and viruses at a wound, surgical, or burn site, or normal tissue times of risk of infecti...
04/09/1996
5194255Antihypertensive hyperimmune milk, production, composition, and use
The invention relates to a method for inducing the production of a milk anti-hypertensive factor in an animal, to a method for the isolation of said factor from the milk of said animal in a substantially pure form, and to the use of said factor to treat h...
03/16/1993
5106618Method of treating protozoal gastrointestinal disorders by administering hyperimmune milk product
The invention comprises treatment of gastrointestinal disorders of parasitic protozoan and bacterial origin in immunocompromised and immunocompetent animals by administration hyperimmune milk products....
04/21/1992
4965068Polyvalent hyperimmunoglobulin preparation
The present invention involves a polyvalent hyperimmunoglobulin preparation having activity against gram negative and gram positive bacteria. Such a polyvalent hyperimmunoglobulin preparation is prepared from plasma, serum or whole blood from donors. Dono...
10/23/1990
4897265Method for treating disorders of the vascular and pulmonary systems
A method for treating vascular disorders or pulmonary disorders associated with smoking in an animal which comprises: administering to the animal milk collected from a bovid being maintained in a hyperimmune state, in an amount and for a time sufficient t...
01/30/1990
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