Bizarre Patents
Crispy Chip Sandwich and Process of Producing a Sandwich Product
A food product comprising a multilayer cookie or snack having outer layers formed from a crispy type edible food product such as a potato chip or corn chip, etc. with an intermediate marshmallow layer being in contact with the inner surface of each crispy chip and one or more filler substances.
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| Number | Title | Issue Date |
| 7341728 | Internalisation of virus into cells A chimeric transmembrane protein which promotes viral entry into cells comprises: (i) an extracellular domain capable of binding a virus; and (ii) an intracellular internalisation signal. ... | 03/11/2008 |
| 7326416 | Inhibition of HIV-1 virion production by a transdominant mutant of integrase interactor 1(INI1)/hSNF5 Peptides comprising an Rpt1 domain of an INI1/hSNF5 which inhibit HIV-1 production in a human cell, and vectors encoding those peptides are provided. Also provided are methods of inhibiting HIV-1 production in a cell, or spread of the HIV-1 to another cell, by treat... | 02/05/2008 |
| 7312320 | Neutralizing antibodies and methods of use thereof This invention provides monoclonal antibodies that recognize the Toll-like Receptor 4/MD-2 receptor complex, and monoclonal antibodies that recognize the TLR4/MD2 complex as well as TLR4 when not complexed with MD-2. The invention further provides methods of using t... | 12/25/2007 |
| 7223844 | Broadly cross-reactive neutralizing antibodies against human immunodeficiency virus selected by Env-CD4-co-receptor complexes The present invention features antibodies and antibody fragments that specifically bind a CD4-inducible HIV gp120 epitope that is enhanced by binding a co-receptor for HIV, such as CCR5 or CXCR4, and pharmaceutical compositions comprising the antibodies or antibody ... | 05/29/2007 |
| 7122188 | Antibodies which bind with proteins of human immunodeficiency virus type 1 (HIV-1), and immune complexes comprising proteins of HIV-1 This invention provides antibodies which bind with p12 and p18 proteins of a human immunodeficiency virus type 1 (HIV-1), antibodies which bind with immune complexes comprising p12 or p18 proteins of HIV-1, mixtures of antibodies which bind with p12, p15, p18, p25, ... | 10/17/2006 |
| 7115262 | Chimeric protein for prevention and treatment of HIV infection This invention relates to bispecific fusion proteins effective in viral neutralization. More specifically, such proteins have two different binding domains, an inducing-binding domain and an induced-binding domain, functionally linked by a peptide linker. Such prote... | 10/03/2006 |
| 7045130 | Antibodies against antigens of human immunodeficiency virus (HIV-1) This invention is in the field of lymphadenopathy virus, which has been designated Human Immunodeficiency Virus Type 1 (HIV-1). This invention relates to a diagnostic means and method to detect the presence of DNA, RNA or antibodies of the lymphadenopathy retrovirus... | 05/16/2006 |
| 7041293 | HIV env antibodies The invention provides antibodies specific for HIV env, including monoclonal antibodies and related hybridomas. The antibodies block CD4/g120 binding and reduce reverse transcriptase activity in vitro. ... | 05/09/2006 |
| 7008622 | Methods and compositions for impairing multiplication of HIV-1 A composition which elicits antibodies to greater than 95%, and even greater than 99%, of the known variants of HIV-1 Tat protein contains at least one peptide or polypeptide of the formula of Epitope I (based on amino acids 2-10 of HIV-1 Tat consensus sequence) and... | 03/07/2006 |
| 6814964 | Supramolecules containing binding and therapeutic molecules bound to hybridized nucleic acids A supramolecule has a first supramolecular component including a first effector molecule covalently joined to a first nucleic acid, and a second supramolecular component including a second effector molecule covalently joined to a second nucleic acid, wherein the sec... | 11/09/2004 |
| 6803449 | Nef-attachable protein A monoclonal antibody specific to Nap was prepared by using a crude membrane fraction from a cell line which has a high affinity to Nef as an antigen. A cDNA clone which encodes Nap was obtained by screening a cDNA library of said cell line utilizing the specific an... | 10/12/2004 |
| 6723558 | Preparation and use of viral vectors for mixed envelope protein vaccines against human immunodeficiency viruses Polyenv vaccines are provided that comprise mixtures of at least 4 to about 10,000 different recombinant viruses that each express a different HIV env variant or a portion thereof containing both constant and variable regions, as well as methods of making and using ... | 04/20/2004 |
| 6703019 | Cationized antibodies against intracellular proteins The subject application discloses methods and compositions for the targeted detection and/or inhibition of an intracellular protein in a cell by contacting the cell with a cationized antibody which reacts specifically with the intracellular protein. An ex... | 03/09/2004 |
| 6692745 | Compositions and methods for inhibition of HIV-1 infection This invention provides a composition which comprises an admixture of two compounds, wherein one compound retards attachment of HIV-1 to a CD4+ cell by retarding binding of HIV-1 gp120 envelope glycoprotein to CD4 on the surface of the CD4+ cell and the o... | 02/17/2004 |
| 6596497 | Screening of antiviral compounds targeted to the HIV-1 gp41 core structure A method for the screening of antiviral compounds targeted to the HIV gp41 core structure comprising capturing polyclonal antibodies from an animal other than a mouse directed against a trimer of a heterodimer containing an N-peptide and a C-peptide onto ... | 07/22/2003 |
| 6586392 | Conjugates of antiviral proteins or peptides and virus or viral envelope glycoproteins The present invention provides antiviral proteins, peptides and conjugates, as well as methods of obtaining these agents. The antiviral proteins, peptides and conjugates of the present invention can be used alone or in combination with other antiviral age... | 07/01/2003 |
| 6566095 | Compositions and methods for preventing transepithelial transmission of HIV Methods, compositions and articles for blocking transepithelial transmission of HIV with ICAM-1 angonist/antagonists are provided. The ICAM-1 agonist/antagonists block viral transmission at the site of exposure to the virus. Blocking viral transmission do... | 05/20/2003 |
| 6558961 | Immunodiagnostics using particle delivery methods Methods for assessing immunocompetence, cellular or humoral immunity, antigen exposure, or allergic conditions in an individual by accelerating diagnostic particles into a target skin site in the individual are provided.... | 05/06/2003 |
| 6524582 | Methods and compositions for impairing multiplication of HIV-1 A composition which elicits antibodies to multiple known variants of Tat protein of HIV-1 of both the B and non-B clades contains the peptide R1-Asp-Pro-Asn-Leu-Asp-Pro-Trp-Asn-R2 SEQ ID NO: 23, and preferably an additional at least two variants of a pept... | 02/25/2003 |
| 6511830 | Killer T cell receptor recognizing human immunodeficiency virus The present invention relates to a polypeptide which is a constituent of a killer T cell receptor and is capable of injuring human immunodeficiency virus-infected cells; a DNA encoding this polypeptide; a recombinant vector comprising this DNA and a vecto... | 01/28/2003 |
| 6440416 | Vaccines against cancer and infectious diseases A method of stimulating an immune response in a human against malignant cells or an infectious agent comprises the step of administering to the human an immunogenic amount of a primate anti-idiotype antibody or antibody fragment that acts as an immunogeni... | 08/27/2002 |
| 6432633 | Immunoassay method of HIV-1p24 antigen and reagent therefor An immunoassay method of the HIV-1p24 antigen by sandwich method, using at least one polyclonal antibody recognizing the HIV-1p24 antigen and at least two monoclonal antibodies recognizing the HIV-1p24 antigen, is provided together with a reagent therefor... | 08/13/2002 |
| 6420336 | Methods of using cyanovirins topically to inhibit viral infection The present invention provides antiviral proteins, peptides and conjugates, as well as methods of obtaining these agents. The antiviral proteins, peptides and conjugates of the present invention can be used alone or in combination with other antiviral age... | 07/16/2002 |
| 6413515 | Avian, vitelline antibodies directed against HIV antigens The present invention is drawn to avian vitellin antibodies that are immunologically reactive with HIV antigens, a process for the preparation thereof, a use thereof and a food substance in the form of a hen's egg containing the antibodies. The antibodies... | 07/02/2002 |
| 6410318 | Antibodies directed against binding-associated epitopes Binding of two members of a binding couple reveals epitopes which are revealed only after binding and the monoclonal antibody secreted from the hybridoma cell line CG-10 directed against these epitopes bind to the bound couple at a significantly higher af... | 06/25/2002 |
| 6395275 | Synthetic human neutralizing monoclonal antibodies to human immunodeficiency virus The present invention describes synthetic human monoclonal antibodies that immunoreact with and neutralize human immunodeficiency virus (HIV). The synthetic monoclonal antibodies of this invention exhibit enhanced binding affinity and neutralization abili... | 05/28/2002 |
| 6379699 | Liposome having attached target-binding moiety and artherosclerotic plaque interacting moiety Complexes are prepared containing two or more different effector molecules joined to each other by a joining component. One effector molecule is a binding molecule such as an antibody or Fc receptor that binds to a molecular target such as a virus or anti... | 04/30/2002 |
| 6329202 | Antibodies directed against binding associated epitopes Binding of two members of a binding couple reveals epitopes which are revealed only after binding and the monoclonal antibody secreted from the hybridoma cell line CG-10 directed against these epitopes bind to the bound couple at a significantly higher af... | 12/11/2001 |
| 6316190 | Oligonucleotides which specifically bind retroviral nucleocapsid proteins The invention provides oligonucleotides which bind to retroviral nucleocapsid proteins with high affinity, molecular decoys for retroviral nucleocapsid proteins which inhibit viral replication, targeted molecules comprising high affinity oligonucleotides,... | 11/13/2001 |
| 6261558 | Synthetic human neutralizing monoclonal antibodies to human immunodeficiency virus The present invention describes synthetic human monoclonal antibodies that immunoreact with and neutralize human immunodeficiency virus (HIV). The synthetic monoclonal antibodies of this invention exhibit enhanced binding affinity and neutralization abili... | 07/17/2001 |
| 6248582 | Gene deleted recombinant FeLV proviral DNA for production of vaccines against FeLV Methods and compositions for a vaccine against feline leukemia are disclosed.... | 06/19/2001 |
| 6248515 | Methods for the early detection of HIV infection Methods for the early detection of HIV infection by detecting a change in signal transduction mediator activity, particularly, an enzyme mediator, more particularly a member of the src protein tyrosine kinase family. The methods are applicable to HIV dete... | 06/19/2001 |
| 6241986 | Human monoclonal antibodies to the CD4-binding domain of HIV, uses thereof and synergistic neutralization of HIV Human monoclonal antibodies specific for the CD4-binding domain of HIV gp120 are useful in the neutralization of HIV and in the prevention of HIV infection and the treatment of a subject infected with HIV. Such antibodies and heterohybridomas producing th... | 06/05/2001 |
| 6235466 | Method for the early detection of HIV infection Methods for the early detection of HIV infection by detecting a change in signal transduction mediator activity, particularly, an enzyme mediator, more particularly a member of the src protein tyrosine kinase family. The methods are applicable to HIV dete... | 05/22/2001 |
| 6228361 | IgG-1 human monoclonal antibody reactive with an HIV-1 antigen and methods of use The present invention provides a human-mouse myeloma analog, designated HMMA 2.11TG/O, which has been deposited with the American Type Culture Collection (ATCC) under Accession Number HB 9583. The invention also provides a hybridoma designated F 105, whic... | 05/08/2001 |
| 6177549 | Non-peptidyl moiety-conjugated CD4-gamma2 and CD4-IgG2 immunoconjugates, and uses thereof This invention provides an immunoconjugate which comprises 1) a non-peptidyl toxin and 2) a CD4-gamma2 chimeric heavy chain homodimer linked thereto. This invention also provides an immunoconjugate which comprises 1) a gamma radiation-emitting radionuclid... | 01/23/2001 |
| 6143876 | Antibodies directed against binding-associated epitopes Binding of two members of a binding couple reveals epitopes which are revealed only after binding and the monoclonal antibody secreted from the hybridoma cell line CG-10 directed against these epitopes bind to the bound couple at a significantly higher af... | 11/07/2000 |
| 6140043 | Pharmaceutical compositions for competitively inhibiting the binding of a retrovirus to the IFN-receptor and means for diagnosis of an HIV infection The present invention is based on the observation that HIV does not only interact with the CD4 receptor of target cells but that there exists a different type of interaction between HIV envelope protein and the IFN receptor of the target cell. Thus, block... | 10/31/2000 |
| 6114143 | Anti-HIV monoclonal antibody A monoclonal antibody useful for clinical application which recognizes the conserved region of V3-PND region of glycoprotein antigen having a molecular weight of about 1.2×105 daltons (gp120) on a coating membrane of human immunodeficiency vir... | 09/05/2000 |
| 6066323 | Use of antibodies to sialidase as anti-infectious agents and anti-inflammatory agents Sialic acids have the ability to prevent hyposialylation of cells as comptive inhibitors of endogenous sialidase. It is now also possible to develop antibodies to mammalian sialidase that significantly reduce influx of neutrophils into inflammatory sites... | 05/23/2000 |
