An aircraft having vertical takeoff and landing capability provided with at least first and second laterally extending paddle wheels rotatable on a central axis perpendicular to the longitudinal axis of the aircraft fuselage and between its nose and tail.
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| Number | Title | Issue Date |
| 7405275 | Antibodies which bind human CXCR3 Antibodies and antigen-binding fragments of antibodies that bind human CXCR3 are disclosed. In preferred embodiments, the antibodies are human. Nucleic acids and vectors encoding the antibodies or portions thereof, recombinant cells that contain the nucleic acids, a... | 07/29/2008 |
| 7384642 | Canine influenza vaccines The present invention encompasses influenza vaccines, in particular canine influenza vaccines. The vaccine may be a recombinant poxvirus vaccine or an inactivated vaccine. The invention also encompasses recombinant poxvirus vectors encoding and expressing influenza ... | 06/10/2008 |
| 7341722 | Method for the stabilization of chimeric immunoglobulins or immunoglobulin fragments, and stabilized anti-EGP-2 scFv fragment The present invention relates to a method for stabilizing chimeric immunoglobulins or immunoglobulin fragments. Furthermore, the invention also provides a stabilized anti-EGP-2 scFv fragment. ... | 03/11/2008 |
| 7335367 | Treatment of chronic chalazion and hordeolum with botulinum toxin Chalazia and hordeola are the most common lesions occurring in the human eyelid, and often recurrences are managed by surgical intervention to remove fatty inclusions within the lid with associated inflammatory reaction. The present invention provides non-surgical m... | 02/26/2008 |
| 7211389 | Method for producing immunoglobulins containing protection proteins and their use The immunoglobulins of the present invention are useful therapeutic immunoglobulins against mucosal pathogens such as S. mutans. The immunoglobulins contain a protection protein that protects the immunoglobulins in the mucosal environment. The invention also ... | 05/01/2007 |
| 7118741 | Transepithelial transport of molecular species There is disclosed a synthetic cross-linker protein capable of binding a molecule or macromolecular species to a transcytosis receptor for transport of the molecule or macromolecule species across a mucous membrane, said cross-linker protein comprising a first bindi... | 10/10/2006 |
| 6998267 | Method for manufacturing glycoproteins having human-type glycosylation The present invention provides a method for manufacturing a glycoprotein having a mammalian-type or human-type sugar chain comprising a step in which a transformed plant cell is obtained by introducing to a plant cell a gene encoding a glycosyltransferase enzyme and... | 02/14/2006 |
| 6852319 | Method of use of transgenic plant expressed antibodies The present invention relates to expression and assembly of foreign multimeric proteins—e.g., antibodies—in plants, as well as to transgenic plants that express such proteins. In one of several preferred embodiments, the generation and assembly of functional sec... | 02/08/2005 |
| 6818213 | Cancer treatment compositions comprising therapeutic conjugates that bind to aminophospholipids Disclosed is the surprising discovery that aminophospholipids, such as phosphatidylserine and phosphatidylethanolamine, are specific, accessible and stable markers of the luminal surface of tumor blood vessels. The present invention thus provides aminophospholipid-t... | 11/16/2004 |
| 6803039 | Human monoclonal antibody against a costimulatory signal transduction molecule AILIM Immunization of human antibody-producing transgenic mice, which have been created using genetic engineering techniques, with AILIM molecule as an antigen resulted in various human monoclonal antibodies capable of binding to AILIM and capable of controlling a variety... | 10/12/2004 |
| 6713610 | Human antibodies derived from immunized xenomice Fully human antibodies against a specific antigen can be prepared by administering the antigen to a transgenic animal which has been modified to produce such antibodies in response to antigenic challenge, but whose endogenous loci have been disabled. Various subsequ... | 03/30/2004 |
| 6603869 | Method of using perimeter measurements to improve ploidy analysis in a tissue section A method for correcting quantitative DNA measurements in a tissue section in which an operator measures, using an image analysis apparatus, the DNA content, profile area, and profile perimeter data for a plurality of nuclei and truncated nuclei in a Feulg... | 08/05/2003 |
| 6593103 | HIV capsid assembly-associated compositions and method A cell-free method for translation and assembly of retroviral, particularly HIV, capsid and capsid intermediates is disclosed. Also disclosed are novel HIV capsid assembly intermediates and novel host proteins which bind to such assembly intermediates. Th... | 07/15/2003 |
| 6406693 | Cancer treatment methods using antibodies to aminophospholipids Disclosed are the surprising discoveries that aminophospholipids, such as phosphatidylserine and phosphatidylethanolamine, are stable and specific markers accessible on the luminal surface of tumor blood vessels, and that the administration of an anti-ami... | 06/18/2002 |
| 6123941 | Method for restoration of normal phenotype in cancer cells A method for reversing expression of malignant phenotype in cancer cells is described. The method comprises applying 댡 integrin function-blocking antibody to the cells. The method can be used to assess the progress of cancer therapy. Hum... | 09/26/2000 |
| 6100446 | Microorganisms and plasmids for 2,4-dichlorophenoxyacetic acid (2,4-D)monooxygenase formation and process for the production of these plasmids and strains The disclosure relates to the production and the use, by genetic engineering, of plasmids and bacterial strains containing, on a short, precisely characterizable DNA segment, the gene tfdA or a gene almost identical to tfdA. The novel plasmids and microor... | 08/08/2000 |
| 5846536 | Restoration of normal phenotype in cancer cells A method for reversing expression of malignant phenotype in cancer cells is described. The method comprises applying 댡 integrin function-blocking antibody to the cells. The method can be used to assess the progress of cancer therapy. Hum... | 12/08/1998 |
| 5798448 | AL-1 neurotrophic factor antibodies The present invention provides nucleic acids encoding AL-1 protein, as well as AL-1 protein produced by recombinant DNA methods. Such AL-1 protein is useful in preparing antibodies and in diagnosing and treating various neuronal disorders.... | 08/25/1998 |
| 5753204 | Biosynthetic binding proteins for immunotargeting Disclosed is a formulation for targeting an epitope on an antigen expressed in a mammal. The formulation comprises a pharmaceutically acceptable carrier together with a dimeric biosynthetic construct for binding at least one preselected antigen. The biosy... | 05/19/1998 |
| 5736136 | Immunoglobulin infusion in xenotransplantation Intravascular introduction of pooled immunoglobulin is employed prior to xenotransplantation to extend the effective lifetime of the donor organ. In particular, intravenous administration of concentrated immunoglobulin for intravenous use (IVIg) by itself... | 04/07/1998 |
| 5202422 | Compositions containing plant-produced glycopolypeptide multimers, multimeric proteins and method of their use The present invention contemplates glycopolypeptide multimers having a polypeptide that contain an immunoglobulin amino acid residue sequence and an oligosaccharide that comprises a core pentasaccharide and N-acetylglucosamine-containing outer branches, s... | 04/13/1993 |