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An armor with rollers is provided that enables a user to move in all positions by rolling on a hard and smooth surface while constantly varying his bearing points on the ground.
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| Number | Title | Issue Date |
| 7183054 | Assay for identifying biological targets of polynucleotide-binding compounds The present invention provides methods and systems for the identification of a biological target of a chemical compound, such as saframycin A, known to bind a polynucleotide. The invention also provides methods of screening chemical compounds for those which act in ... | 02/27/2007 |
| 7129261 | Cytotoxic agents The present invention provides analogues of duocarmycins that are potent cytotoxins. Also provided are peptidyl and disulfide linkers that are cleaved in vivo. The linkers are of use in forming prodrugs and conjugates of the cytotoxins of the invention as well as ot... | 10/31/2006 |
| 7122549 | Saframycins, analogues and uses thereof In recognition of the need to develop novel therapeutic agents and efficient methods for the synthesis thereof, the present invention provides novel compounds of general formula (I), and methods for the synthesis thereof. ... | 10/17/2006 |
| 7087600 | Peptidyl prodrugs and linkers and stabilizers useful therefor The present invention provides analogues of duocarmycins that are potent cytotoxins. Also provided are peptidyl and disulfide linkers that are cleaved in vivo. The linkers are of use in forming prodrugs and conjugates of the cytotoxins of the invention as well as ot... | 08/08/2006 |
| 6855524 | Method for producing exopolysaccharides The invention concerns a method for producing exopolysaccharides by fermenting micro-organisms characterised in that it consists in carrying out the fermentation in a nutrient medium comprising at least a source of carbon available to the micro-organisms and at leas... | 02/15/2005 |
| 6482082 | Heating and/or air-conditioning system for an automobile and method of making same In a heating and/or air-conditioning system especially for an automobile with a blower housing and a distributor housing located in front of and below an instrument panel, provision is made such that the distributor housing can be separated toward the veh... | 11/19/2002 |
| 6306629 | Microorganism streptomyces exfoliatus yj-118 and a method for producing pravastatin sodium by using the strain The present invention is related to a new microorganism Streptomyces exfoliatus YJ-118 and a method for producing pravastatin sodium by using this microorganism which shows a strong tolerance to ML-236B and a high hydroxylation activity of ML-236B to prav... | 10/23/2001 |
| 6207186 | Lamellar gels and methods for making and using The invention provides novel compositions involving lamellar gels and methods for making them. These compositions and methods of the invention are significant improvements in the field of gels, macromolecular targeting and macromolecular delivery to vario... | 03/27/2001 |
| 6171612 | Lipopolyamines as transfection agents and pharmaceutical uses thereof Lipopolyamines useful for the transfection of nucleic acid and methods of preparation thereof are disclosed. The lipopolyamines are of general formula I, in which R4 comprises at least one C10-C22 aliphatic radical. ##STR1##... | 01/09/2001 |
| 6132764 | Targeted polymerized liposome diagnostic and treatment agents Polymerized liposome particles which are linked to a targeting agent and may also be linked to a contrast enhancement agent and/or linked to or encapsulating a treatment agent. The targeting imaging enhancement polymerized liposome particles interact with... | 10/17/2000 |
| 5994318 | Cochleate delivery vehicles The instant disclosure relates to cochleates comprising a) a biologically relevant molecule component b) a negatively charged lipid component, and c) a divalent cation component. The cochleate has an extended shelf life, even in a desiccated state. Advant... | 11/30/1999 |
| 5567676 | Glycopeptide antibiotics The present invention concerns new antiobiotic substances demoninated de-acyl antibiotics A40926, de-acyl antibiotic A 40926P and antibiotic A 40926 amino glucronyl aglycon, and the use of these substances in the treatment of infectious diseases involving... | 10/22/1996 |
| 5545542 | WB2663 substances and method for their production WB2663 substance-producing bacteria belonging to the genus Pseudomonas are cultured to produce a physiologically active substance, from which are isolated neutral substances WB2663A, WB2663B and WB2663C having respective specific rotations []D... | 08/13/1996 |
| 5378463 | Antitumor antibiotic A certain fermentation product of Actinomadura strain Q473-8 yield, when suitably treated, a novel compound having both antibiotic and antitumor activities.... | 01/03/1995 |
| 5332574 | Compounds produced by a strain of Streptomyces exfoliatus Disclosed are active compounds BU-4726G-A and BU-4726G-B which contain a quinone chromophore and hydroquinone chromophore, respectively. The compounds are produced by fermentation of Streptomyces exfoliatus AA4510. The compounds possess antimicrobial, and... | 07/26/1994 |
| 5304373 | Antitumor antibiotic A certain fermentation product of Actinomadura strain Q473-8 yields, when suitably treated, a novel compound having both antibiotic and antitumor activities.... | 04/19/1994 |
| 5281417 | Antitumor process employing novel fermentate of an Actinomadura strain A certain fermentation product of Actinomadura strain Q473-8 yields, when suitably treated, a novel compound having both antibiotic and antitumor activities.... | 01/25/1994 |
| 5073369 | Efomycins as performance promoters in animals The present invention relates to the use of microbiologically prepared compounds and their mixtures, which are called efomycins, as performance promoters in farm animals and processes for their preparation, and furthermore new efomycins and their mixtures... | 12/17/1991 |
| 5066585 | Method of inhibiting fungus using novel antifungal compounds A new species of Micromonospora, in particular Micromonospora spartanea ATCC 53803, is described. The species produces antifungal compounds spartanamicins A and B. Methods for the production, isolation and characterization of the compounds are described. ... | 11/19/1991 |
| 4977084 | Production, isolation, and identification of novel antifungal compounds A new species of Micromonospora, in particular Micromonospora spartanea ATCC 53803, is described. The species produces new antifungal compounds spartanamicins A and B. Methods for the production, isolation and characterization of the compounds are describ... | 12/11/1990 |
| 4960694 | Test combination and method of detecting fibrin monomers in blood A test reagent for detecting fibrin monomers in blood, comprises an antibiotic of a pyrrole amidine series as a precipitant, introduced in a buffer solution. A method of detecting fibrin monomers in blood, comprises the steps of mixing venous blood with a... | 10/02/1990 |
| 4670260 | Antibiotic for animal feeds A novel antibiotic for combating bacteria and promoting animal growth is obtained by cultivating Streptomyces strain BA 9.... | 06/02/1987 |
| 4548814 | Composition of matter and process Novel antibiotics didemnins A, B and C (didemnins), and nordidemnins A, B and C (nordidemnins) which can be obtained from a marine organism. These antibiotics are active against a variety of DNA and RNA viruses; thus, they can be used in various environme... | 10/22/1985 |
| 4512975 | Macbecin derivatives and their production Macbecin derivatives are produced by cultivating a microorganism of the genus Actinosynnema in a culture medium. The Macbecin derivatives are useful as antibacterial, antifungal or antiprotozoal agent.... | 04/23/1985 |
| 4424212 | K-41.C(2) esters This invention relates to K-41.C(2) esters, miticidal compositions comprising K-41.C(2) esters and anti-coccidial compositions comprising K-41.C(2) esters.... | 01/03/1984 |
| 4421687 | Macbecin derivatives Macbecin derivatives are produced by cultivating a microorganism of the genus Actinosynnema in a culture medium. The Macbecin derivatives are useful as antibacterial, antifungal or antiprotozoal agent.... | 12/20/1983 |
| 4420474 | Synergistic antifungal compositions Synergistic activity against Candida albicans and Trichomonas vaginalis is obtained when an antifungal imidazole is combined with an antimicrobial agent selected from the group anisomycin, ascomycin, azalomycin F, brefeldin A, copiamycin, EM4940A, or EM49... | 12/13/1983 |
| 4372947 | Antibiotic saframycin S and process for producing the same Antibiotic substance named saframycin S having antibacterial activities and produced by decyanating antibiotic saframycin A or cultivating Streptomyces lavendulae strain No. 314 and recovering saframycin S from a cultured broth.... | 02/08/1983 |
| 4336249 | Antibiotic substance A novel antibiotic substance, named "Mycoplanecin", of presently unknown structural formula, is produced by cultivating a Mycoplanecin-producing microorganism of the genus Actinoplanes, especially the Actinoplanes nov. sp. Strain No. 41042, NRRL No. 11462... | 06/22/1982 |
| 4331658 | Method of treating swine dysentery with antibiotic A-32887 Method and compositions for treatment of swine dysentery with antibiotic A-32887 (K-41). Antibiotic A-32887 is produced by submerged aerobic fermentation of Streptomyces albus NRRL 11109.... | 05/25/1982 |
| 4331659 | Antibiotic U-62,162 and process of making Novel antibiotic U-62,162 producible in a fermentation under controlled conditions using a man-made biologically pure culture of the microorganism Streptomyces verdensis, Dietz and Li sp.n., NRRL 12256. This antibiotic is strongly active against various G... | 05/25/1982 |
| 4306021 | Composition of matter and process Novel antibiotic U-60, 394 producible in a fermentation under controlled conditions using a biologically pure culture of the microorganism Streptomyces woolenses, Dietz and Li sp.n., NRRL 12113. This antibiotic is strongly active against various Gram-posi... | 12/15/1981 |
| 4303647 | Method of treating coccidiosis with antibiotic A-32887K Methods and compositions for treatment of coccidiosis in poultry with antibiotic A-32887 (K-41). Antibiotic A-32887 is produced by submerged aerobic fermentation of Streptomyces albus NRRL 11109.... | 12/01/1981 |
| 4291021 | Novel macrolide antibiotics and preparation thereof A novel microorganism species belonging to the genus Micromonospora, i.e. Micromonospora sp. A 11725 is found to be capable of producing novel macrolide antibiotics A 11725 I, A 11725 II and A 11725 III. Novel antibiotics A 11725 Ia and A 11725 IIa are al... | 09/22/1981 |
| 4289757 | Method for treating inflammation A method of treating inflammation comprising topical administration to mammals suffering from an inflammatory condition not associated with amicrobial component, employing selected antibiotics as the anti-inflammatory agent.... | 09/15/1981 |
| 4278663 | Antibiotic X-14868A, B, C and D Antibiotic X-14868A having the following chemical structure ##STR1## and the pharmaceutically acceptable salts thereof is presented. Also presented is a fermentative method of producing the above antibiotic. Antibiotic X-14868A exhibits anticoccidiostatic... | 07/14/1981 |
| 4263404 | Rifamycin R and microorganisms useful in the production of rifamycins Novel rifamycin compounds, designated P, Q, R and U, produced by the fermentation of mutant strains of Streptomyces mediterranei.... | 04/21/1981 |
| 4248863 | Antibiotics saframycins A, B, C, D and E and process for producing the same Antibiotic substances named saframycins A, B, C, D and E having antibacterial activity and activity against transplantable tumors. It is produced by cultivation of Streptomyces lavendulae strain No. 314.... | 02/03/1981 |
| 4209509 | Substance SF-1739 derivatives, process for preparing the same and antibacterial compositions containing the same Substance SF-1739 derivatives, Substance SF-1739 HP, Substance SF-1739 HP-C, Substance SF-1739 HP-F, Substance SF-1739 HP-3 and Substance SF-1739 HP-5, the physico-chemical properties of which derivatives are described in the specification; processes for ... | 06/24/1980 |
| 4191825 | Diacyloxyacids derived from acid S, an antibiotic produced by Polyangium cellulosum var. fulvum The present invention relates to diacyloxyacids derived from the antibiotic substance, designated acid S, produced by Polyangium cellulosum var. fulvum (ATCC No. 25532), and to processes for their production. The diacyloxyacids derivatives of acid S of th... | 03/04/1980 |
