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| Number | Title | Issue Date |
| 7807151 | Probiotic, lactic acid-producing bacteria and uses thereof The present invention discloses compositions and methodologies for the utilization of probiotic organisms in therapeutic compositions. More specifically, the present invention relates to the utilization of one or more species or strains of lactic acid-producing bact... | 10/05/2010 |
| 7341742 | Simethicone containing tablet composition and method A process and pharmaceutical composition containing simethicone and magnesium carbonate allows a higher production rate of simethicone containing tablets and a more consistent end product tablet. The magnesium carbonate prevents sticking of simethicone to tablet com... | 03/11/2008 |
| 7329670 | Inhibition of RAF kinase using aryl and heteroaryl substituted heterocyclic ureas The compounds are aryl and heteroaryl substituted heterocyclic ureas of the formula A—NH—C(O)—NH—B where A is the aryl or hetaryl substituted heterocyclic group and B is an aryl or heteroaryl moiety. The compounds inhibit raf kinase and are useful in the tre... | 02/12/2008 |
| 7282221 | Antiviral product, use and formulation thereof An antiviral product is comprised of at least three dosages forms, each of which has a different release profile, with the Cmax for the antiviral product being reached in less than about twelve hours. In one embodiment, there is an immediate release dosag... | 10/16/2007 |
| 7247622 | Pharmaceutical compositions containing oxapenem-3-carboxylic acids An oxapenem compound which is, or is capable of forming, a zwitterion of formula wherein R is a C1-C8 branched or straight chain alkyl group which is substituted by ... | 07/24/2007 |
| 7235900 | Switching apparatus and method for varying a phase line impedance of an electric power transport line section The switching apparatus and method are provided for varying the impedance of a phase line of a segment of an electrical power line. The phase line includes n conductors electrically insulated from each other and short-circuited among each other at two ends of the se... | 06/26/2007 |
| 7211562 | Methods for enhancing the efficacy of cytotoxic agents through the use of HSP90 inhibitors The administration of cytotoxic agents followed by the administration of heat shock protein 90 inhibitors, such as ansamycins, has a synergistic effect on the growth inhibition of cells. This synergy occurs at doses of each cytotoxic agent that normally only causes ... | 05/01/2007 |
| 7211394 | Detection of markers in nascent proteins The invention is directed to methods for the non-radioactive labeling, detection, quantitation and isolation of nascent proteins translated in a cellular or cell-free translation system. tRNA molecules are misaminoacylated with non-radioactive markers which may be n... | 05/01/2007 |
| 7189351 | D-tagatose as an anti-biofilm agent There is disclosed a method for disrupting biofilm and for inhibiting biofilm formation in an aqueous environment that comprises contacting said environment with an effective amount of D-tagatose. ... | 03/13/2007 |
| 7166270 | Methods of screening compounds useful for prevention of infection or pathogenicity Screening procedures are disclosed for identifying compounds useful for inhibiting infection or pathogenicity. Methods are also disclosed for identifying pathogenic virulence factors. ... | 01/23/2007 |
| 7125986 | Penicillanic acid derivative compounds and methods of making Compounds of formula I: wherein R1, R2, R3, R4 and n have any of the values defined in the specification, and their pharmaceutically acceptable salts, are useful for in... | 10/24/2006 |
| 7122204 | Antibiotic composition with inhibitor Antibiotic composition having four dosage forms with different release profiles providing for initial release of a beta lactam antibiotic followed by release of a beta-lactamase inhibitor, followed by release of the antibiotic followed by release of the inhibitor. I... | 10/17/2006 |
| 7091197 | Beta-lactamase inhibitor prodrug Prodrugs of 6-β-hydroxymethylpenicillanic acid sulfone having the structure wherein R is H or methyl, and solvates thereof, are disclosed. Also disclosed are pharmaceutical compositions comprising a prodrug of t... | 08/15/2006 |
| 7029704 | Anti-itch solution The anti-itch solution is a solution of hydrogen peroxide, sodium bicarbonate and apple cider vinegar applied to feet to prevent a common fungal infection of feet known as “athlete's foot”. ... | 04/18/2006 |
| 6919179 | Detection of markers in nascent proteins The invention is directed to methods for the non-radioactive labeling, detection, quantitation and isolation of nascent proteins translated in a cellular or cell-free translation system. tRNA molecules are misaminoacylated with non-radioactive markers which may be n... | 07/19/2005 |
| 6916801 | 7-Alkylidene-3-substituted-3-cephem-4-carboxylates as β-lactamase inhibitors The invention provides compounds of formula (I): wherein: R1-R4 and A have any of the values defined in the specification, and their pharmaceutically acceptable salts, are useful for inhibiting β... | 07/12/2005 |
| 6906054 | Compositions for inhibiting beta-lactamase The invention provides pharmaceutical compositions comprising compounds of formula I and IV: wherein R1-R11 and A have any of the values defined in the specification, and ... | 06/14/2005 |
| 6861053 | Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth Disclosed is a method of diagnosing irritable bowel syndrome, fibromyalgia, chronic fatigue syndrome, depression, attention deficit/hyperactivity disorder, autoimmune diseases, such as multiple sclerosis and systemic lupus erythematosus, or Crohn's disease, which in... | 03/01/2005 |
| 6726908 | Pharmaceutical formulation This invention relates to pharmaceutical formulations comprising amoxycillin and a salt clavulanic acid in a ratio of 14:1. ... | 04/27/2004 |
| 6673375 | Composition of multipurpose high functional alkaline solution composition, preparation thereof, and for the use of nonspecific immunostimulator Disclosed are a multipurpose, high-functional, alkaline solution composition, preparation therefor and use thereof as a nonspecific immunostimulator. The composition comprises 1-25 parts by weight of borax (Na2 B4 O7.10H.sub.2 | 01/06/2004 |
| 6635260 | Methods and compositions for prevention and treatment of Clostridium difficile-associated diseases This invention provides methods and compositions for preventing and treating Clostridium difficile-associated disease in a subject, wherein the subject is either a human or non-human animal. The method comprises administering to the subject an effective a... | 10/21/2003 |
| 6558618 | Anti-infection formulation and delivery method A method of dispersing, in water vapor, an anti-infective therapeutic composition (10) into the air in a room (36), in order to treat or prevent transmission of upper respiratory infections, includes: adding to a reservoir of liquid water in a vaporizer (... | 05/06/2003 |
| 6511972 | Pharmaceutical suspension formulation comprising amoxycillin clavulanic acid and cellulose A liquid aqueous pharmaceutical suspension formulation containing as amoxycillin trihydrate, potassium clavulanate and microcrystalline cellulose filler is provided.... | 01/28/2003 |
| 6472383 | Pharmaceutical formulations A pharmaceutical formulation comprises, in combination with a penem of formula (I): ##STR1## in which: R1 is hydrogen or an organic substituent group; R2 is a fused bicyclic heterocyclic ring system of general formula: ##STR2## wher... | 10/29/2002 |
| 6461627 | Skin preparations for external use Skin preparations for external use and cosmetics which contain a fermented soybean extract prepared by extracting with an organic solvent a fermentation product obtained by treating a soybean extract with one or more microorganisms selected from bifidobac... | 10/08/2002 |
| 6447810 | Composition of multipurpose high functional alkaline solution composition, preparation thereof, and for the use of nonspecific immunostimulator Disclosed are a multipurpose, high-functional, alkaline solution composition, preparation therefor and use thereof as a nonspecific immunostimulator. The composition comprises 1-25 parts by weight of borax (Na2 B4 O7.10H.sub.2 | 09/10/2002 |
| 6436398 | 2 ଲ-substituted-6-alkylidene penicillanic acid derivatives as ଲ-lactamase inhibitors Compound of formula I: ##STR1## wherein R1, R2, R3, R4 and n have any of the values defined in the specification, and their pharmaceutically acceptable salts, are useful for inhibiting ଲ-lactamase enzymes,... | 08/20/2002 |
| 6369050 | Antibacterial agents The invention provides an antimicrobial agent capable of producing an excellent effect in the prevention or treatment of bacteria of two or more genera selected from among Streptococcus, Moraxella, Haemophilus, Klebsiella and the like. The agent comprises... | 04/09/2002 |
| 6328989 | Use of bicozamycin for the manufacture of a medicament for treating infections with enterohemorrhagic e. coli The present invention relates to the use of bicozamycins for the prophylaxis and treatment of infections with a verotoxin-producing E. coli, as well as for eradicating verotoxin-producing E. coli in livestock.... | 12/11/2001 |
| 6281191 | Compositions and methods for treating hepatitis-C New compositions and methods for treating patients suffering from hepatitis-C, AIDS, aberrant apoptosis which include N-acetyl-D-glucosaminyl(ଲ-1-4)-N-Acetyl-muramyl-L-ananyl-D-isoglutami ne (GMDP) of at least 98% purity and provided either alone, as... | 08/28/2001 |
| 6277829 | Process for preparing of aqueous formulation for opthalmic use The present invention describes a process for the preparation of aqueous formulations containing azithromycin for ophthalmic use, as well any formulations obtained by this process and their topical use in the ocular bacterial infections, more preferably i... | 08/21/2001 |
| 6277374 | Process for producing by culturing Lactobacillus casei var. rhamnosus yeast and mold inhibiting products A method for producing a novel yeast and mold inhibiting products (FIC) from a Lactobacillus, particularly a Lactobacillus casei having the yeast and mold producing characteristics of Lactobacillus casei var. rhamnosus NRRL-B-15972 is described. The produ... | 08/21/2001 |
| 6140306 | Method of treating gram-negative bacterial infection by administration of bactericidal/permeability-increasing (BPI) protein product and antibiotic The present invention relates to methods and compositions for treating gram-negative bacterial infections, using BPI protein products. Co-treatment, or concurrent administration, of BPI protein product with an antibiotic in treatment of gram-negative bact... | 10/31/2000 |
| 6054431 | Anti-gram-positive bacterial methods and materials The present invention relates to methods of treating gram-positive bacterial infections by administration of a BPI protein product alone, or in combination with an antibiotic. BPI protein product alone has a bactericidal or growth inhibitory effect on sel... | 04/25/2000 |
| 6015808 | Synthesis of pharmaceutical compositions with lactams and ଲ-lactams/oxo thia azabicyclo compounds Pharmaceutical compositions with heretofore unknown and enhanced physical, chemical, and biological properties are prepared by combining known biologically active parent compounds with oxo thia azabicyclo compounds, such as lactam and ଲ-lactam compo... | 01/18/2000 |
| 5998182 | Deterioration inhibitor for emulsion-type processing oil and method for inhibiting deterioration of emulsion-type processing oil using the same Disclosed are a deterioration inhibitor for an emulsion-type processing oil comprising, as an active ingredient, a culture of a bacterial species selected from the group consisting of Aerococcus viridans BC-A-4 (Acceptance No. FERM BP-5042), Bacillus brev... | 12/07/1999 |
| 5981234 | Use of antibiotics 10381b to promote growth Antibiotic 10381a1, wherein R is hydrogen, is a cytosine-containing antibiotic producible by culturing the novel microorganism Streptomyces arginensis in an aqueous medium and isolation thereof. Derivatives wherein R is a C1 to C | 11/09/1999 |
| 5939066 | Pharmaceutical formulations A pharmaceutical formulation comprises, in combination with a penem of formula (I): ##STR1## in which: R1 is hydrogen or an organic substituent group; R2 is a fused bicyclic heterocyclic ring system of general formula: ##STR2## ... | 08/17/1999 |
| 5911985 | Pharmaceutical formulations containing a ଲ-lactamase inhibiting penem in combination with ଲ-lactam antibiotic and their use in the treatment of bacterial infections A pharmaceutical formulation comprises, in combination with a penem of formula (I), in which: R1 is hydrogen or an organic substituent group; R2 is a fused bicyclic heterocyclic ring system of general formula (a), wherein R4 | 06/15/1999 |
| 5783561 | Anti-gram-positive bacterial methods and materials The present invention relates to methods of treating gram-positive bacterial infections by administration of a BPI protein product alone, or in combination with an antibiotic. BPI protein product alone has a bactericidal or growth inhibitory effect on sel... | 07/21/1998 |