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Behavior Modification Wristwatch

A wristwatch including a watch band and a watch body having an octagon shaped perimeter and being red in color and having the word STOP thereon to resemble a stop sign.

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Class 424/1.81 - Nonmetal radionuclide or intended radionuclide (e.g., carbon)


Subclass of Class 424 - Drug, bio-affecting and body treating compositions
Definition: Subject matter in which the radionuclide or intended radionuclide
No. of patents: 210
Last issue date: 02/15/2011


1            
NumberTitleIssue Date
78877841-[(2′-substituted)-piperazin-1′ -yl]-isoquinolines as norepinephrine transporter inhibitor therapeutics and positron emission tomography imaging agents
Racemic mixtures and enantiomerically pure forms of novel 1-[(2′-substituted)-piperazin-1′-yl]-isoquinolines are norepinephrine (NE) transporter (NET) inhibitor compounds. Compounds of the invention are considered therapeutic agents for central nervous system (C...
02/15/2011
7846419Method for producing radioactive isotopes for positron emission tomography
A method for producing radioactive isotopes for positron emission tomography is provided. The method includes generating radioactive isotopes by the acceleration of a projectile in a linear accelerator that is operative to accelerate at least two different projectil...
12/07/2010
7794691Radionuclides for medical use
Methods of using Th-226 or mother radionuclides thereof, namely U-230 or Th-226, in medicine. These radionuclides are particularly appropriate for the treatment of human and/or non-human mammals, in particular for therapeutic, diagnostic (detection/imaging), prophyl...
09/14/2010
7727511Agents for imaging soluble a-beta
Provided herein are agents that bind to soluble beta-amyloid. Also provided are in vivo and in vitro methods for detecting soluble beta-amyloid in a sample that may include brain tissue. ...
06/01/2010
7670591Heteroaryl substituted benzoxazoles
The present invention relates to novel heteroaryl substituted benzoxazole derivatives and therapeutic uses for such compounds, having the structural formula (Ia) below: and to their pharmaceutically acceptable salt, composi...
03/02/2010
7662360Conjugates of N-hydroxypropymethacrylamide-methacrylate copolymer with nuclide activation agent and/or anti-cancer compounds
The present invention relates to new anti-cancer compounds and in particular to new compounds for use in nuclide activation therapy, such as neutron capture therapy. Specifically this invention provides a conjugate having the general formula P-(L-NAT)n wh...
02/16/2010
7569208Diagnostic agents for pancreatic exocrine function
The present invention provides a 13C-labeled oligosaccharide or polysaccharide or a salt thereof excluding U—13C-maltose, 13C-starch, 1-13C-maltotetraose and 1-13C-amylose; a derivative of the 13C-l...
08/04/2009
7560095Cancer specific monoclonal antibodies
Novel monoclonal antibodies and binding fragments thereof specific to human breast cancer, lung cancer, colon cancer and other cancers. The monoclonal antibody does not bind to the cell surface of normal human tissues. The corresponding cancer-specific antigen or an...
07/14/2009
7534418Imaging agents
The present invention provides novel compounds that find use as imaging agents within nuclear medicine applications (e.g., PET imaging and SPECT imaging). The present invention also provides imaging compositions for use within nuclear medicine applications. Addition...
05/19/2009
7514068Biphenyl-pyrazolecarboxamide compounds
The present invention relates to biphenyl-pyrazole compounds and in particular biphenyl-pyrazolecarboxamides. The invention further provides compositions comprising a compound of this invention and the use of such compositions in methods of treating diseases and con...
04/07/2009
7488466Preparation for determining pyrimidine metabolic capacity
The present invention provide a method for measuring and assessing the capacity in an individual subject to metabolize a variety of fluorouracil drugs, such as 5-fluorouracil, which are degraded in the pyrimidine metabolic pathway, and a preparation useful for the m...
02/10/2009
7438891Imaging agents for early detection and monitoring of cardiovascular plaque
The present invention relates in part to a method of imaging cardiovascular plaque formation in a mammal comprising administering to the mammal an effective amount of 18F-2-fluorodeoxy-D-glucose and then detecting the 18F-2-fluorodeoxy-D-glucos...
10/21/2008
7427389Diagnostic agents for positron emission imaging using radiolabeled halogenated xanthenes
New diagnostic agents for positron emission tomography (PET) and methods for use of such agents for imaging of human or animal tissue are described, wherein a primary active component of such agents is a radiolabeled halogenated xanthene or halogenated xanthene deri...
09/23/2008
7427390Radiohalogenated benzamide derivatives and their use in tumor diagnosis and tumor therapy
This invention relates to new radiohalogenated benzamide derivatives and their use in tumor diagnosis and tumor therapy. The radiohalogenated benzamide derivatives according to the invention exhibit novel and especially advantageous properties, in particular with re...
09/23/2008
7413727Contrast agents
The invention provides a composition of matter of the formula (I): V-L-R, where V is a vector moiety having affinity for an angiogenesis-related endothelias cell receptor, L is a linker moiety or a bond and R is a detectable moiety, characterised in that V is a non-...
08/19/2008
7404945Method of evaluating pharmacological effects of medicine
A diagnostic reagent for use in the evaluation of a pharmacological effect of a medicine containing a pharmaceutical agent including an enzyme, an enzyme inhibitor or a receptor ligand or a prodrug of the pharmaceutical agent is provided. Further, a method of screen...
07/29/2008
7381400Injection of a radioactive dye for sentinel lymph node identification
A one-step procedure for sentinel lymph node identification and biopsy using a single compound, a radiolabeled, low molecular weight dye (e.g., 125I-labeled methylene blue). This radiolabled dye is mixed with an unlabeled, similar molecular weight dye (e....
06/03/2008
7378079Agents for imaging and diagnostic methods using them
The present invention provides novel compounds that bind selectively to cells undergoing perturbations and alterations of the normal organization of their plasma membrane, while binding to a lesser degree to cells having membranes of normal organization, and their u...
05/27/2008
7351397Stabilization of radiopharmaceutical compositions using hydrophilic 6-hydroxy chromans
Radiopharmaceutical compositions which are stabilized by addition of a hydrophilic 6-hydroxy-chroman derivative. ...
04/01/2008
7351398Stabilization of radiopharmaceutical compositions using hydrophilic thioethers
Radiopharmaceutical compositions which are stabilized by addition of a hydrophilic thioether. ...
04/01/2008
7351401Thioflavin derivatives for use in the antemortem diagnosis of Alzheimers disease and in vivo imaging and prevention of amyloid deposition
This invention relates to novel thioflavin derivatives, methods of using the derivatives in, for example, in vivo imaging of patients having neuritic plaques, pharmaceutical compositions comprising the thioflavin derivatives and method of synthesizing the compounds....
04/01/2008
7341709Compositions for labeling β-amyloid plaques and neurofibrillary tangles
Compositions useful for labeling β-amyloid plaques and neurofibrillary tangles are provided. The compositions comprises compounds of formula (I): wherein R1 is selected from the group consisting of —C(O)-alkyl...
03/11/2008
7338444Management of gastro-intestinal disorders
The present invention relates to the field of methods and apparatus for the determination of various conditions of gastric and gastro-intestinal malfunction, especially those performed by means of breath tests. ...
03/04/2008
7338652Methods for positron emission imaging with radiolabeled halogenated xanthenes diagnostic agents
New diagnostic agents for positron emission tomography (PET) and methods for use of such agents for imaging of human or animal tissue are described, wherein a primary active component of such agents is a radiolabeled halogenated xanthene or halogenated xanthene deri...
03/04/2008
7335347Methods for purifying radiolabelled compounds
One aspect of the present invention relates to a method of purifying radiolabelled compounds comprising a) loading onto a fluorous polymer a radiolabelled compound precursor comprising a fluoroalkyl tin moiety; b) reacting the radiolabelled compound precursor with a...
02/26/2008
7332149Vitronectin receptor antagonist pharmaceuticals
The present invention describes novel compounds of the formula: (Q)d—Ln—Ch, useful for the diagnosis and treatment of cancer, methods of imaging tumors in a patient, and methods of treating cancer in a patient...
02/19/2008
7329401Cyclooxygenase-2 selective agents useful as imaging probes and related methods
This invention provides novel cyclooxygenase-2 selective agents that are particularly useful as imaging probes in non-invasive imaging techniques, such as PET and SPECT. Preferred cyclooxygenase-2 selective agents inhibit cyclooxygenase-2 activity with greater poten...
02/12/2008
7321049Synthesis of [C] and [H] substituted methacrylic acid, [C] and [H] substituted methyl methacrylate and/or related compounds
The present invention is directed to labeled compounds of the formulae wherein Q is selected from the group consisting of —S—, —S(═O)—, and —S(═O)2—, Z is selec...
01/22/2008
7321045Vitronectin receptor antagonist pharmaceuticals
The present invention describes novel compounds of the formula: (Q)d-Ln-Ch, useful for the diagnosis and treatment of cancer, methods of imaging tumors in a patient, and methods of treating cancer in a patient. Th...
01/22/2008
7314609Stereoisomers of fatty acid analogs for diagnostic imaging
The present invention provides novel imaging agents for clinical diagnosis of injuries and diseases, in the form of a radionuclide in spatial proximity to a substantially pure stereoisomer of a fatty acid analog. The invention also provides methods for using the nov...
01/01/2008
7306785Multifunctional cross-bridged tetraaza macrocyclic compounds and methods of making and using
A multifunctional cross-bridged tetraaza macrocyclic compound has at least one side arm that comprises a moiety that is capable of forming a bond with another molecule, which has a targeting moiety that directs the compound to a site a marker substance. The compound...
12/11/2007
7297325Hydrophilic light absorbing compositions for determination of physiological function
Highly hydrophilic indole and benzoindole derivatives that absorb and fluoresce in the visible region of light are disclosed. These compounds are useful for physiological and organ function monitoring. Particularly, the molecules of the invention are useful for opti...
11/20/2007
7291628Treatment of cocaine abuse using N-substituted derivatives of morphinan
The invention is based in part on the discovery that nonselective κ agonists that possess μ receptor-mediated effects in addition to their κ agonist effects can decrease cocaine self-administration more effectively and with fewer undesirable side effects than can...
11/06/2007
7282223Nutritional dietary kit for use in preparing an individual for gastrointestinal procedure
This invention relates to a nutritional kit for use in preparing an individual for a predetermined activity which requires a clean digestive tract, particularly the colon. Such predetermined activities include, but are not limited to, gastrointestinal surgery and co...
10/16/2007
7279502Polyamine analog conjugates and quinone conjugates as therapies for cancers and prostate diseases
Peptide conjugates in which cytocidal and cytostatic agents, such as polyamine analogs or naphthoquinones, are conjugated to a polypeptide recognized and cleaved by enzymes such as prostate-specific antigen (PSA) and cathepsin B are provided, as well as compositions...
10/09/2007
7273601Preparation of radiolabelled haloaromatics via polymer-bound intermediates
According to a first aspect of the invention, a process is disclosed for the preparation of radiolabelled haloaromatic compounds. According to a second aspect of the invention, intermediate precursor insoluble polymer compounds used in the preparation of the radiola...
09/25/2007
7273600[18F]-furanosylpurine derivatives and uses thereof
2′-Deoxy-2′-[18F]-labeled and 3′-deoxy-3′-[18F]-labeled purine nucleoside analogs such as [18F]-FAA and [18F]-FXA have been found to have desirable properties for use as imaging agents. The analogs are particularly...
09/25/2007
7270800Thioflavin derivatives for use in antemortem diagnosis of Alzheimer's disease and in vivo imaging and prevention of amyloid deposition
This invention relates to novel thioflavin derivatives, methods of using the derivatives in, for example, in vivo imaging of patients having neuritic plaques, pharmaceutical compositions comprising the thioflavin derivatives and method of synthesizing the compounds....
09/18/2007
7267990Chelation of charged and uncharged molecules with porphyrin-based compounds
Porphyrins containing one or more neutral or negatively-charged, closo- or nido-carborane substituents are useful as chelators. The carbon-carbon bonds linking the boron-containing groups to the porphyrin ring make the compounds highly resistant to hydrolysis. These...
09/11/2007
7265199Poly-tri-fluoro-ethoxypolyphosphazene coverings and films
The present invention relates to an anti-thrombogenic, physically well-tolerated polymer and its use for manufacturing sheaths and films as a component of therapeutic devices for preventing excessive cell proliferation. Furthermore, it relates to films made from the...
09/04/2007
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