...that the video game, Pong, was invented by a guy who graduated at the bottom of his engineering class? Nolan Bushnell spent more time running the games at a local amusement park than he did on his studies at the University of Utah. His dreams of working for Disney's amusement empire were dashed when the company wouldn't hire him. Taking a boring job, Nolan daydreamed about electronic versions of popular games. He invented Pong, the first video game, and went on to found Atari Co.
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| Number | Title | Issue Date |
| 7803350 | Radioactive arsenic-containing compounds and their uses in the treatment of tumors This invention provides a process for producing a radioactive arsenic-containing compound, comprising the steps of: (i) subjecting an arsenic-containing compound to a neutron irradiation treatment, said arsenic-containing compound being selected from a group consist... | 09/28/2010 |
| 7722857 | Immunoadjuvant An immunoadjuvant comprising one kind or two or more kinds of immunostimulating substances carried separately by two or more kinds of different microparticle immunostimulating substance carriers, and comprising at least a combination of (a) an inorganic substance su... | 05/25/2010 |
| 7364859 | Methods of using bioelastomers Bioelastomers are disclosed for use in methods of binding compounds including immunoassay methods, in biosensors and methods or regenerating biosensors, and in methods for targeting the delivery of a compound to a particular location within an animal subjects. In ge... | 04/29/2008 |
| 7357913 | Methods for detecting, prognosing, or monitoring a disorder by comparing relative flux rates of two or more biological molecules in vivo The invention relates to techniques for measuring and comparing relative molecular flux rates of different biological molecules by administering isotope-labeled water to one or more tissues or individuals and comparing the molecular flux rates of two or more biologi... | 04/15/2008 |
| 7329400 | Generator for rhenium-188 Radioisotope generators comprising inorganic layered hydroxide composition, such as magnesium aluminates and lithium aluminates. These inorganic layered hydroxides form anion exchange materials that exhibit surprisingly high selective affinities for certain radioiso... | 02/12/2008 |
| 7266173 | Method for distillation of sulfur for the preparing radioactive phosphorous nuclide A method for distillation of sulfur for preparing radioactive phosphorous nuclide includes the steps of: charging powdered sulfur into a target tube designed to have an upper and a bottom neck; degassing the target tube to form a vacuum therein, followed by heating ... | 09/04/2007 |
| 7265199 | Poly-tri-fluoro-ethoxypolyphosphazene coverings and films The present invention relates to an anti-thrombogenic, physically well-tolerated polymer and its use for manufacturing sheaths and films as a component of therapeutic devices for preventing excessive cell proliferation. Furthermore, it relates to films made from the... | 09/04/2007 |
| 7194360 | Method of determining radioactive nuclides A method of simply and quickly determining α-ray releasing nuclides having long half-life without carrying out a chemical separation is provided. By inputting a data of pulses incident to an α-ray detector in a computer, obtaining time distribution of the i... | 03/20/2007 |
| 7150867 | Radionuclide-coated particulate material This invention relates to a particulate material comprising an inorganic low density, radiation tolerant core coated with a radionuclide, processes for its production and a method of radiation therapy utilizing the particulate material. ... | 12/19/2006 |
| 7118524 | Dosimetry for californium-252 (Cf) neutron-emitting brachytherapy sources and encapsulation, storage, and clinical delivery thereof The present invention discloses a methodology for the characterization and determination of mixed-field dosimetry for 252Cf Applicator Tube (AT)-type medical sources, utilizing ionization chambers, GM counters, and Monte Carlo methods. Unlike the previous... | 10/10/2006 |
| 7109341 | Therapeutic amides The invention provides compounds of the formula: wherein A, X, Y, and Z are as defined in the specification. The compounds are effective anti-tumor agents. The invention also provides pharmaceutical compositions ... | 09/19/2006 |
| 7056275 | Radiotherapy The invention provides a method of radiation treatment of a human or non-human mammalian subject which comprises administering to said subject a therapeutically, prophylactically or pain-palliating amount of a bone-targeting complex of an alpha-particle emitting tho... | 06/06/2006 |
| 7018609 | Compositions containing inclusion complexes The invention provides a composition containing particulate composite of a polymer and a therapeutic agent. The composition also contains a complexing agent. The polymer interacts with the complexing agent in a host-guest or a guest-host interaction to form an inclu... | 03/28/2006 |
| 7011814 | Systems, methods and devices for in vivo monitoring of a localized response via a radiolabeled analyte in a subject Methods, systems, devices and computer program products monitor in vivo detected radiation in a target localized site within a subject, over a selected time period, to do one or more of: (a) quantify a radiation dose received at a local site; (b) assess bioreceptive... | 03/14/2006 |
| 6804319 | High specific activity platinum-195m A new composition of matter includes 195mPt characterized by a specific activity of at least 30 mCi/mg Pt, generally made by method that includes the steps of: exposing 193Ir to a flux of neutrons sufficient to convert a portion of the 193... | 10/12/2004 |
| 6635234 | Preparation and use of radium-223 to target calcified tissues for pain palliation, bone cancer therapy, and bone surface conditioning Processes for the preparation, prepared solutions, and the use of radium-223 for the treatment of calcified tumors, bone tumors, treatment of bones, bone surfaces and soft tissues is described.... | 10/21/2003 |
| 6613303 | Highly radioactive miniaturized ceremic strontium 90 radiation sources and method for the production thereof The present invention relates to highly radioactive, miniaturized, cylindrical strontium 90 titanate, strontium 90 zirconate, and strontium 90 silicate radiation sources having an activity exceeding 25 mCi/mm3, preferably ࣙ30 mCi/mm3 | 09/02/2003 |
| 6565831 | Methods for preventing reovirus recognition for the treatment of cellular proliferative disorders The present invention pertains to methods for preventing reovirus recognition in the treatment of cellular proliferative disorders, and particularly ras-mediated cellular proliferative disorders, in mammals. The method comprises suppressing or otherwise i... | 05/20/2003 |
| 6503481 | Compositions for aerosolization and inhalation A composition used in combination with an electrohydrodynamic device capable of delivering an active ingredient to the aerodigestive system of the user. The composition comprises three or optionally four basic components: an active ingredient; a carrier m... | 01/07/2003 |
| 6455052 | Enteric coating, comprising alginic acid, for an oral preparation A composition for forming an enteric coating on a tablet, capsule or pellet for oral ingestion includes a liquid mixture of alginic acid particles dispersed in an aqueous solution of a binding agent of locust bean, gum, gelatine, vegetable hydrocolloids a... | 09/24/2002 |
| 6409943 | In-situ-generated solid radiation source based on Tungsten 188 /Rhenium 188 and use thereof A radiotheraputical source of Rhenium188 comprises metallic Tungsten188 or a metal oxide of Tungsten188. Therapeutic device using Rhenium188 comprise a radioactive source for the in situ generation of Rhenium | 06/25/2002 |
| 6348184 | Radiopharmaceutical compositions and matrices and uses thereof Novel radiopharmaceutical compositions comprising, in combination with a pharmaceutically acceptable carrier, a radioactive salt of pyrophosphoric acid. Also provided are novel radiopharmaceutical compositions comprising, in combination with one or more p... | 02/19/2002 |
| 6294151 | Isotopic urea tablets The present invention provides a tablet containing isotope-labeled urea and an inorganic compound.... | 09/25/2001 |
| 6248305 | Boron heterocycle steroid mimics and associated pharmaceutical compositions and methods of use Boron heterocycle steroid mimics are provided that are useful as pharmaceutical agents, particularly in the treatment of estrogen-dependent disorders such as estrogen-dependent cancers. The compounds are also useful in diagnostic techniques such as magnet... | 06/19/2001 |
| 6241962 | Radiopharmaceutical compositions and matrices and uses thereof Novel radiopharmaceutical compositions comprising, in combination with a pharmaceutically acceptable carrier, a radioactive salt of pyrophosphoric acid. Also provided are novel radiopharmaceutical compositions comprising, in combination with one or more p... | 06/05/2001 |
| 6238644 | Method for treating and/or imaging breast cancer using radioactive iodide The instant invention utilizes the preferential uptake of iodine by mammary cells in general, and neoplastic mammary cells in particular to promote the concentration of radioactive iodine in malignant mammary cells. Radioactive iodine has utility in the i... | 05/29/2001 |
| 6168777 | Methods for treating prostate tumors using radioactive compositions Disclosed are methods for treating solid mass prostate tumors in a male mammal by use of a radiation composition.... | 01/02/2001 |
| 6149889 | Radioactive particles and methods for preparing same A nuclear medical drug for localize radiotheraphy of a tumor and methods for its preparation. The drug includes a radioactive ceramic or glass particle having biocompatiblity. Ceramic or glass particles prepared by traditional processes become radioactive... | 11/21/2000 |
| 6113876 | Methods of increasing sphincter competence A method of increasing sphincter competence comprising administering to a human in need of treatment an effective amount of a compound having the formula ##STR1## wherein R1 and R3 are independently hydrogen, ##STR2## ... | 09/05/2000 |
| 6099821 | Nuclear scintigraphic assessment of mucosal function A method is provided for assessing the functional integrity of a mucosal membrane, comprising: (a) locally administering a dosage of a radionuclide to the surface of a mucosal membrane of a mammal; and (b) employing dynamic scintigraphy to measure the abs... | 08/08/2000 |
| 6074625 | Boron-containing hormone analogs and methods of their use in imaging or killing cells having hormone receptors Boron containing compounds are targeted to hormonally responsive cells by contacting the cells with a conjugate of a boron containing moiety conjugated to a ligand having binding specificity for an intracellular receptor of the cell. The conjugates are us... | 06/13/2000 |
| 6074626 | Radioactive cisplatin in the treatment of cancer Background: Between 1991 and 1997 sixty-seven patients with non-resectable hepatoma were treated with hepatic artery infusions (HAI) of cisplatinum. Patients were divided into groups for analysis based on alpha-fetoprotein elevation (AFP+) or no elevation... | 06/13/2000 |
| 5891444 | HIV-1 prophylactic composition and method A composition and method for inducing a protective immune response to HIV-1 in an individual, of (a) a replication incompetent HIV-1, HIV-1 pseudovirus, HIV-1 VLP or oligomeric gp120; and (b) a water soluble polyphosphazene polyelectrolyte, wherein (a) an... | 04/06/1999 |
| 5827499 | Determining effects of psychoactive compounds on the brain using positron emission tomography A method of determining the effects of administering a psychoactive compound, such as a drug, on a patient's brain using imaging techniques with position emission tomography (PET) is disclosed. The method measures cerebral metabolism before and after admi... | 10/27/1998 |
| 5667762 | Method for preventing adhesion of thallium 201 to container There is disclosed an agent for preventing the adhesion of thallium 201 to a container which comprises a reducing substance as an active ingredient. There is also disclosed a radioactive diagnostic agent wherein the adhesion of thallium 201 to a container... | 09/16/1997 |
| 5653957 | Halogenated sulfidohydroboranes for nuclear medicine and boron neutron capture therapy A method for performing boron neutron capture therapy for the treatment of tumors is disclosed. The method includes administering to a patient an iodinated sulfidohydroborane, a boron-10-containing compound. The site of the tumor is localized. by visualiz... | 08/05/1997 |
| 5627036 | Use of an anticoagulant as a diagnostic agent Detectably labelled annexines and compositions thereof are disclosed. Also disclosed are methods for diagnosing a disruption or activation of the hemostatic system or a prothrombotic state in an individual suspected of having a hemostatic disorder, by con... | 05/06/1997 |
| 5612017 | Halogenated sulfidohydroboranes for nuclear medicine and boron neutron capture therapy A method for performing boron neutron capture therapy for the treatment of tumors is disclosed. The method includes administering to a patient an iodinated sulfidohydroborane, a boron-10-containing compound. The site of the tumor is localized by visualizi... | 03/18/1997 |
| 5571797 | Method of inducing gene expression by ionizing radiation The present invention provides a method for delivering ionizing radiation to specific tissues, resulting in the activation of a DNA molecule comprising a radiation responsive enhancer-promoter operatively linked to an encoding region that encodes at least... | 11/05/1996 |
| 5524622 | Non-invasive method of determining inflammation of the gastrointestinal tract A non-invasive method of determining the presence of inflammation in a region of the gastrointestinal tract of an organism comprises introducing an arterial dilating agent into the circulatory system that provides blood flow to that region, then introduci... | 06/11/1996 |