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| Number | Title | Issue Date |
| 7776310 | Flexible and/or elastic brachytherapy seed or strand A flexible or elastic brachytherapy strand that includes an imaging marker and/or a therapeutic, diagnostic or prophylactic agent such as a drug in a biocompatible carrier that can be delivered to a subject upon implantation into the subject through the bore of a br... | 08/17/2010 |
| 7459142 | High viscosity embolizing compositions comprising prepolymers Disclosed are novel high viscosity compositions for embolizing blood vessels which comprise a biocompatible prepolymer and a contrast agent, and optionally a thickening agent and/or a biocompatible solvent. Also disclosed are methods for embolizing a vascular site b... | 12/02/2008 |
| 7364748 | Controlled morphologies in polymer drug for release of drugs from polymer films The present invention includes a drug release system. The drug release system comprises a bulk polymer phase and a polymeric drug-enriched phase within the bulk polymer phase. At least one drug is incorporated into the drug-enriched phase. ... | 04/29/2008 |
| 7364859 | Methods of using bioelastomers Bioelastomers are disclosed for use in methods of binding compounds including immunoassay methods, in biosensors and methods or regenerating biosensors, and in methods for targeting the delivery of a compound to a particular location within an animal subjects. In ge... | 04/29/2008 |
| 7363074 | Coatings comprising self-assembled molecular structures and a method of delivering a drug using the same A coating for an implantable medical device is disclosed, the coating including a self-assembled molecular structure. The coating can be used for altering the release rate of a therapeutic substance from the implantable device. ... | 04/22/2008 |
| 7335391 | Method for coating implantable devices A method of forming a coating for an implantable medical device, such as a stent, is provided which includes applying a composition to the device in an environment having a selected pressure. ... | 02/26/2008 |
| 7329413 | Coatings for drug delivery devices having gradient of hydration and methods for fabricating thereof Coatings for implantable medical devices, and methods for fabricating thereof, are provided. The coatings include a first polymer layer and a second polymer layer, where the second polymer has a higher degree of hydration than the first polymer. ... | 02/12/2008 |
| 7329414 | Biodegradable polymer for marking tissue and sealing tracts A tissue marker formed of a biodegradable polymer having drug-delivery capabilities is combined with a sealant that encapsulates the tissue marker and which serves to help anchor the tissue marker against migration. The sealant is delivered to a site in dehydrated f... | 02/12/2008 |
| 7323209 | Apparatus and method for coating stents An apparatus and method is provided for forming coatings on stents. The apparatus includes a temperature adjusting element that can increase or decrease the temperature of the stent. The apparatus can support a stent during the application of a coating composition t... | 01/29/2008 |
| 7318932 | Coatings for drug delivery devices comprising hydrolitically stable adducts of poly(ethylene-co-vinyl alcohol) and methods for fabricating the same A polymer coating for medical devices based on a derivatized poly(ethylene-co-vinyl alcohol) is disclosed. A variety of polymers are described to make coatings for medical devices, particularly, for drug delivery stents. The polymers include poly(ethylene-co-vinyl a... | 01/15/2008 |
| 7316644 | Method for preparing particles of radioactive powder containing Cesium-131 for use in brachytherapy sources The present invention provides a method of preparing Cesium-131 (Cs-131) as a dispersed radioisotope. Uses of the dispersed Cs-131 prepared by the method include cancer research and treatment, such as for the use in brachytherapy. Cs-131 is particularly useful in th... | 01/08/2008 |
| 7311980 | Polyactive/polylactic acid coatings for an implantable device A polymeric coating for a medical device that comprises poly(lactic acid) and a block copolymer including blocks of poly(ethylene glycol) and poly(butylene terephthalate) is provided. ... | 12/25/2007 |
| 7294329 | Poly(vinyl acetal) coatings for implantable medical devices A coating for a medical device, particularly for a drug eluting stent, is described. The coating includes a polyacetal-based polymer. ... | 11/13/2007 |
| 7288609 | Coatings for drug delivery devices based on poly (orthoesters) A polymer coating for implantable medical devices based on polyorthoesters and methods for fabricating the coating are disclosed. The implantable medical devices made of polyorthoesters and methods for fabricating thereof are also disclosed. ... | 10/30/2007 |
| 7279174 | Stent coatings comprising hydrophilic additives A coating for implantable medical devices and a method for fabricating thereof are disclosed. The coating includes a mixture of a hydrophobic polymer and a polymeric hydrophilic additive, wherein the hydrophobic polymer and the hydrophilic additive form a physically... | 10/09/2007 |
| 7276254 | Emulsion/aggregation polymeric microspheres for biomedical applications and methods of making same A method of forming polymeric microspheres for biomedical applications includes forming polymeric microspheres by an emulsion/aggregation process from a precursor monomer species, and treating the polymeric microspheres to attach a biomedical functional material to ... | 10/02/2007 |
| 7265199 | Poly-tri-fluoro-ethoxypolyphosphazene coverings and films The present invention relates to an anti-thrombogenic, physically well-tolerated polymer and its use for manufacturing sheaths and films as a component of therapeutic devices for preventing excessive cell proliferation. Furthermore, it relates to films made from the... | 09/04/2007 |
| 7261946 | Block copolymers of acrylates and methacrylates with fluoroalkenes A block copolymer comprising a fluorinated block and a non-fluorinated block and method of making the block copolymer are provided. Also provided herein are a coating on an implantable device comprising the block copolymer and method of using the implantable device.... | 08/28/2007 |
| 7247314 | Biocompatible material composition adaptable to diverse therapeutic indications A biocompatible material genus serves as the foundation for multiple material composition species, each adapted to a specific therapeutic indication. ... | 07/24/2007 |
| 7247313 | Polyacrylates coatings for implantable medical devices A coating for a medical device, particularly for a drug eluting stent, is described. The coating can include a polyacrylate, a blend of polyacrylates, or a blend of the polyacrylate with other polymers, for example, poly(ethylene-co-vinyl alcohol). ... | 07/24/2007 |
| 7244443 | Polymers of fluorinated monomers and hydrophilic monomers A polymer of fluorinated monomers and hydrophilic monomers is provided. It is also provided a polymer blend that contains a polymer of fluorinated monomers and another biocompatible polymer. The polymer of fluorinated monomers or polymer blend described herein and o... | 07/17/2007 |
| 7232573 | Stent coatings containing self-assembled monolayers A coating for a medical device, particularly for a drug eluting stent, is described. The coating includes a self-assembled monolayer. ... | 06/19/2007 |
| 7226622 | Chemoablation of tissue using biodegradable, solid salt dosage forms Novel methods for the chemical ablation of tissue (e.g. prostatic tissue) are described. These methods include the steps of: (a) providing one or more solid salt dosage form comprising 50-100% w/w salt; and (b) inserting one or more of such solid salt dosage forms i... | 06/05/2007 |
| 7223282 | Remote activation of an implantable device The invention is directed to an implantable device, such as a stent, for delivering a therapeutic substance. The device includes a reservoir containing a therapeutic substance and an energy converter to cause the release of the substance. ... | 05/29/2007 |
| 7220816 | Biologically absorbable coatings for implantable devices based on poly(ester amides) and methods for fabricating the same Coatings for an implantable medical devices such as stents and methods of fabricating thereof are disclosed. The coatings comprise a biologically absorbable poly(ester amide), which is a polymeric product of a reaction between a diol-diamine and a dicarboxylic acid.... | 05/22/2007 |
| 7217426 | Coatings containing polycationic peptides for cardiovascular therapy Coatings for implantable medical devices and methods for fabricating the same are disclosed. The coatings include a region containing a polycationic peptide, such as, for example, the polycationic peptide known as R7. ... | 05/15/2007 |
| 7211150 | Apparatus and method for coating and drying multiple stents A coating and drying apparatus for the application of a coating substance to a stent and drying the stent is provided. ... | 05/01/2007 |
| 7211039 | Strand with end plug A treatment strand for insertion into a patient using a needle. The strand includes an elongated member having first and second longitudinal ends, and a plurality of treatments seeds spaced apart from one another within the elongated member between the longitudinal ... | 05/01/2007 |
| 7201891 | Pharmaceutical preparation for the diagnosis of helicobacter pylori infection A coated preparation for the detection of a H. pylori infection according to a urea breath test protocol which comprises a core composition containing at least an isotope C-labeled urea, an excipient and a lubricant in defined proportions and covered with 0.1... | 04/10/2007 |
| 7201935 | Plasma-generated coatings for medical devices and methods for fabricating thereof Coatings for implantable medical devices, such as stents, and methods of coating the devices are disclosed. The method includes forming a coating by plasma polymerization of a monomer or a blend of monomers. ... | 04/10/2007 |
| 7186789 | Bioabsorbable, biobeneficial polyester polymers for use in drug eluting stent coatings This disclosure covers polymers, some of which are useful in medical device applications. Some of these medical devices are implantable within a mammalian body, such as in a body lumen. The copolymers comprise at least one alcoholic moiety derived from a diol, triol... | 03/06/2007 |
| 7182726 | Brachytherapy device and method The present invention provides a system and method of applying low dose, localized radiotherapy which is effective to reduce or eliminate the formation of post-operative scar tissue at surgical sites, such as an epidural site after spinal surgery. In an exemplary em... | 02/27/2007 |
| 7175873 | Rate limiting barriers for implantable devices and methods for fabrication thereof A method of coating an implantable medical device, such as a stent, is disclosed. The method includes applying a formulation on a first polymer layer containing a therapeutic substance to form a second layer. The formulation can contain a highly hydrophobic polymer ... | 02/13/2007 |
| 7175874 | Apparatus and method for coating implantable devices A coating for implantable devices, such as stents, and a method of making the same is disclosed. Moreover, an apparatus for depositing the coating is disclosed. ... | 02/13/2007 |
| 7169404 | Biologically absorbable coatings for implantable devices and methods for fabricating the same Coatings for an implantable medical device and a method of fabricating thereof are disclosed, the coatings comprising a biologically degradable, biologically erodable, and/or biologically resorbable ABA or AB block copolymer. A biologically active agent can be conju... | 01/30/2007 |
| 7169173 | Composite stent with regioselective material and a method of forming the same A composite stent and a method for making the same are provided. ... | 01/30/2007 |
| 7169178 | Stent with drug coating Coatings for stents that include a polymer and a drug are provided. A method of forming the coatings is also provided. ... | 01/30/2007 |
| RE39456 | Radioactive embolizing compositions Disclosed are novel radioactive compositions which are particularly suited for treating solid mass tumors via catheter delivery. ... | 01/02/2007 |
| 7115300 | Method of coating implantable medical devices A method of coating a medical device, such as a stent is provided. ... | 10/03/2006 |
| 7094256 | Coatings for implantable medical device containing polycationic peptides Coatings for implantable medical devices and methods for fabricating the same are disclosed. The coatings include carboxylated acrylates and polycationic peptides, for example R7. ... | 08/22/2006 |
