Quotables
"During my service in the United States Congress, I took the initiative in creating the Internet."
Al Gore ; The basis for the later misquote by US Republicans that Gore had "invented" the Internet. Gore was the leading political champion of the modern-day Internet.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 8163241 | Optical probe An optical probe for detecting luminescence emitted by a sample is disclosed. The optical probe includes a parabolic optical waveguide and an outer housing having a detachable component configured to hold a transparent sensor substrate that can be coupled to the opt... | 04/24/2012 |
| 8153066 | Device for supporting chromophore elements A device for supporting chromophore elements suitable for emitting fluorescence in response to light excitation, the device comprising a substrate having a surface layer carrying the chromophore elements, forming a planar waveguide, and containing photoluminescent c... | 04/10/2012 |
| 8062595 | Nucleic acid analysis chip integrating a waveguide and optical apparatus for the inspection of nucleic acid probes A chip for nucleic acid analysis includes a body (2, 9), in which a detection chamber (7) is formed for accommodating nucleic acid probes (12, 12′). A waveguide (8) is integrated in the body (2, 9) is and is arranged at the botto... | 11/22/2011 |
| 7968060 | Wave guide with isolated coupling interface A wave-guide having an isolated coupling interface. In one variation, a constant negative pressure is maintained around the area surrounding the wave-guide. Coupling liquid may be directed to the tip of the wave-guide to provide the coupling interface between the wa... | 06/28/2011 |
| 7943092 | Portable surface plasmon resonance biosensor A surface plasmon resonance biosensor device and system are provided. The simplicity of SPR biosensor design allows easy integration with both QCM and electrochemistry techniques, not found in current SPR biosensor devices. In some embodiments, the surface plasmon r... | 05/17/2011 |
| 7935310 | Uniform surfaces for hybrid material substrate and methods for making and using same Devices, systems and methods of using same where hybrid substrate materials are provided with a substantially uniform surface to provide uniformity of properties, including interaction with their environments. Uniform surfaces are applied as coatings over, e.g., hyb... | 05/03/2011 |
| 7922976 | High sensitivity sensor device and manufacturing thereof A sensing device able to do concurrent real time detection of different kinds of chemical, biomolecule agents, or biological cells and their respective concentrations using optical principles. The sensing system can be produced at a low cost (below $1.00) and in a s... | 04/12/2011 |
| 7867448 | Optical sensor and optical process for the characterization of a chemical and/or bio-chemical substance The optical sensor contains an optical waveguide (1) with a substrate (104), waveguiding material (105), a cover medium (106) and a waveguide grating structure (101-103). By means of a light source (2), light can be e... | 01/11/2011 |
| 7842243 | Chemical sensor with an indicator dye A chemical sensor based on an indicator dye wherein a light transmissive element containing the indicator dye is made of a hygroscopic polymer. The polymer may be, for example, a polyimide or PMMA or other polymer. In an alternative embodiment the light transmissive... | 11/30/2010 |
| 7820107 | Optical reagents format for small sample volumes An optical waveguiding optical format enables consistent optical analysis of small sample volumes with minimal variation in light path length among optical formats. The optical format is comprised of an input guide, an output guide, and a sample cavity adapted to al... | 10/26/2010 |
| 7731902 | Photonic crystal and waveguide sensor device The present invention provides a sensor device for detecting a substance contained in a fluid comprising a first photonic crystal region, a second photonic crystal region, a first channel which is connected to the first photonic crystal region, and passes the fluid ... | 06/08/2010 |
| 7682567 | Sensor for analyzing or identifying property of object, sensing apparatus using same, and sensing method A sensor is provided which comprises a waveguide for allowing an electromagnetic wave to propagate therethrough and disposing an object at a plurality of positions thereof, and a detecting portion for detecting the electromagnetic wave which has interacted with the ... | 03/23/2010 |
| 7582261 | Electricity supplying device, electricity supplying apparatus, sample detection device, and sample detection apparatus A sample detection device includes a disk substrate which allows a light beam to be transmitted, and the substrate has flow paths each of which allows polymers to be injected therein, wherein the substrate further includes a guiding groove, provided in a perpendicul... | 09/01/2009 |
| 7537734 | Integrated optic waveguide immunosensor A composite waveguide for evanescent sensing in fluorescent binding assays comprising a substrate layer having one or more thin-film waveguide channels deposited thereon. Binding molecules having the property of binding with specificity to an analyte are immobilized... | 05/26/2009 |
| 7462326 | Device for the detection of at least one ligand contained in a sample that is to be analyzed Disclosed is a device for detecting at least one ligand contained in a sample that is to be analyzed. Said device comprises an optical waveguide, on the surface of which at least one ligand-specific receptor is directly or indirectly immobilized. The ligand bonds to... | 12/09/2008 |
| 7438854 | Biomolecule substrate, and test and diagnosis methods and apparatuses using the same A test apparatus is for testing a DNA substrate on which a plurality of DNA fragments for testing are arranged, wherein absolute precision is not required. A substrate is provided on which a plurality of biomolecule spots containing a group of biomolecules (e.g., DN... | 10/21/2008 |
| 7439078 | Method for measuring dissociation rate coefficient by surface plasmon resonance analysis An object of the present invention is to provide a method for measuring the dissociation rate coefficient (Kd) by surface plasmon resonance analysis without measuring the theoretical maximum amount of binding (Rmax). The present invention provides a method for measu... | 10/21/2008 |
| 7429492 | Multiwell plates with integrated biosensors and membranes The invention provides compositions and methods of detecting binding of molecules to a biosensor. Compositions of the invention comprise a multiwell plate with an integrated biosensor and a membrane. ... | 09/30/2008 |
| 7419636 | Vapor sensing instruments for ultra trace chemical detection A detector for detecting vapors emitted from analytes includes a housing, a pump and a sensing assembly. The housing has an inlet, an outlet and an enclosed sensing volume therebetween. The pump communicates with the housing for moving a carrier sequentially through... | 09/02/2008 |
| 7416701 | Calibrator for fluorosensor A multichannel fluorosensor includes an optical module and an electronic module combined in a watertight housing with an underwater connector. The fluorosensor has an integral calibrator for periodical sensitivity validation of the fluorosensor. The optical module h... | 08/26/2008 |
| 7413911 | Method for measuring reaction rate coefficient by surface plasmon resonance analysis An object of the present invention is to provide a method for measuring a rate coefficient by surface plasmon resonance analysis with excellent accuracy, reliability, and cost performance that can improve the assay accuracy and simplify the apparatus. The present in... | 08/19/2008 |
| 7410614 | Optical waveguide type iontophoresis sensor chip and method for packaging sensor chip An optical waveguide type iontophoresis sensor chip has a substrate having a first hinged plate and a second hinged plate, an optical waveguide plate connected to the first hinged plate and positioned over a first opening delineated in the first hinged plate, and a ... | 08/12/2008 |
| 7407628 | Biosensor and method of manufacturing biosensor Aspects of the invention can be an inexpensive biosensor capable of measuring a number of samples in a short time, and suitable for only one-time use (expendable). The biosensor according to the invention can include a light transmissive substrate, a probe fixing re... | 08/05/2008 |
| 7407817 | Surface plasmon resonance sensors and method for detecting samples using the same Disclosed is an optical sensing device including a source unit providing a beam of light with continuously modulated phase retardation between p- and s-polarization components of the light by employing a LCM; a reference unit receiving a first part of the light to p... | 08/05/2008 |
| 7405054 | Signal amplification method for surface plasmon resonance-based chemical detection The present invention provides methods and compositions for amplifying the detection signal in surface plasmon resonance (SPR)-based flow systems. The signal amplification methods comprise the use of well established marker systems that provide a precipitate. The ma... | 07/29/2008 |
| 7402441 | Method of detecting an analyte in a fluid A method for the detection of an analyte in a fluid, comprising contacting the fluid with a holographic element comprising a medium and a hologram disposed throughout the volume of the medium, wherein an optical characteristic of the element changes as a result of a... | 07/22/2008 |
| 7402381 | Method of immobilizing molecules onto a solid phase substrate and method of fabricating a biosensor using the method Aspects of the invention can provide a method capable of easily realizing immobilization with the optimum density derived from a concentration control and without phase separation in coadsorption of a number of molecules. The immobilization method can include the st... | 07/22/2008 |
| 7399628 | Body for flow-through cells and the use thereof A system of flow-through cells is obtained by assembling a body with a base plate. The body has a first spring element and a first stop, disposed on opposite end sections of the body, at least one second spring element and a corresponding second stop, disposed on op... | 07/15/2008 |
| 7399445 | Chemical sensor A sensor device is formed from a metal film having a plurality of openings, a sensor material positioned within each of the openings, a light source that emits light having a first wavelength, and a light detector that detects light emitted from the light source and... | 07/15/2008 |
| 7396675 | Kit and method for determining a plurality of analytes The invention is related to different embodiments of a kit for the simultaneous qualitative and/or quantitative determination of a multitude of analytes comprising a sensor platform comprising an optical thin-film waveguide with a ... | 07/08/2008 |
| 7396676 | Evanescent wave sensor with attached ligand The invention in particular embodiments provides an evanescent wave sensor which includes a ligand bound to a sensor substrate via a NCYX linker moiety, as defined herein. Methods of making the subject evanescent wave sensors are also provided which include contacti... | 07/08/2008 |
| 7390463 | Microcolumn-based, high-throughput microfluidic device A biological assay device for use in molecular biology, pharmaceutical research, genomic analysis, combinatorial chemistry, and in the general field of the analysis of molecules that may be deposited on supports of various kinds is provided. Specifically, the presen... | 06/24/2008 |
| 7390669 | Simultaneous and rapid determination of multiple component concentrations in a Kraft liquor process stream The present invention is a rapid method of determining the concentration of the major components in a chemical stream. The present invention is also a simple, low cost, device of determining the in-situ concentration of the major components in a chemical stream. In ... | 06/24/2008 |
| 7387901 | Target substance detecting element, target substance detection apparatus and target substance detection method Magnetic particles with a metal coat holding target substance captors are made to react with a target substance contained in a specimen in a solution where the magnetic particles are dispersed in a liquid medium. Subsequently, the dispersion of the magnetic particle... | 06/17/2008 |
| 7384797 | Resonant optical cavities for high-sensitivity high-throughput biological sensors and methods Biosensors including resonant optical cavities. The resonant optical cavities are shaped so as to generate whispering gallery modes, which increase the quality factors of the cavities and facilitate the detection of analytes in a sample with enhanced sensitivity. Th... | 06/10/2008 |
| 7381565 | Flow cytometers and detection system of lesser size Gas focusing flow cytometers are fabricatable employing simple and inexpensive manufacturing techniques. When such cytometers or conventional cytometers are combined with fiber optical light paths and laser diode and semiconductor photodetectors, light weight and ha... | 06/03/2008 |
| 7378283 | Reaction monitoring of chiral molecules using fourier transform infrared vibrational circular dichroism spectroscopy A method and apparatus to monitor the enantiomeric excess of chiral molecules participating in a chemical reaction. The method includes real time monitoring of the chemical reaction by obtaining a VCD spectra and an IR spectra of the chemical compounds in the reacti... | 05/27/2008 |
| 7371562 | Guided mode resonant filter biosensor using a linear grating surface structure Methods and compositions are provided for detecting biomolecular interactions. The use of labels is not required and the methods can be performed in a high-throughput manner. The invention also provides optical devices useful as narrow band filters. ... | 05/13/2008 |
| 7368281 | Label-free evanescent-field detection of biological and chemical agents An evanescent-field sensor system and method of using the system to detect either liquid- or airborne biological pathogens, chemical agents, and other harmful or toxic species is provided. The sensor system involves 1) an evanescent-field sensor having a substrate s... | 05/06/2008 |
| 7358079 | Flow cell array and the utilization thereof for multianalyte determination A one- or two-dimensional arrangement of flow cells is provided, as part of an array of sample compartments, with at least one inlet and outlet for each sample compartment, formed by a base plate and a body, with an arrangement of spatial recesses corresponding to t... | 04/15/2008 |
