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| Number | Title | Issue Date |
| 6643015 | System, method, and product for symmetrical filtering in scanning of biological materials An apparatus is described that includes an emission signal detector and an emission signal filter. An excitation beam scans an array of biological materials, and the emission signal detector detects an emission signal indicative of an emission beam respon... | 11/04/2003 |
| 6638483 | Multiwell scanner and scanning method A multiwell plate scanner comprises a detector for measuring an attribute of a sample which is scanned continuously over wells of a multiwell plate. An signal obtained during the scan may be sampled and digitized based on detector position over the multiw... | 10/28/2003 |
| 6635487 | Fluorescence standard for use in microfluidic instruments A test device for use as a fluorescent standard in microfluidic analytical detection systems includes one or more slits that correspond to, and are of similar dimension to, one or more microchannels in a detection region on a corresponding analysis chip. ... | 10/21/2003 |
| 6635224 | Online monitor for polymer processes This invention provides an online polymer monitoring apparatus for rapid determination of molecular weight and/or size, and/or other properties of importance to the polymer quality. The apparatus uses fast sample extraction, preparation and delivery techn... | 10/21/2003 |
| 6633368 | Method for determining the volume of single red blood cells The invention discloses a method for determining the volume of single red blood cells or other particles that are suspended in liquids. The sample is disposed into an optical cuvette suitable for microscopic analysis. A fluorescent dye is added that does ... | 10/14/2003 |
| 6632401 | Device for the detection of a fluorescent dye The present invention relates to a device for the detection of a fluorescent dye in a sample, comprising a radiation source with the aid of which light for exciting the fluorescent dye to be detected can be transmitted into the sample applied to a carrier... | 10/14/2003 |
| 6630570 | Short-chain peptide-dye conjugates as contrast media for optical diagnosis The invention relates to compounds for tumor diagnosis that consist of conjugates of dyes with short-chain peptides, which are derived from vaso-active intestinal peptide, somatostatin or neurotensin, the use of these compounds as optical dignostic agents... | 10/07/2003 |
| 6630356 | Photoluminescent semiconductor materials Semiconductor materials having a porous texture are modified with a recognition element and produce a photoluminescent response on exposure to electromagnetic radiation. The recognition elements, which can be selected from biomolecular, organic and inorga... | 10/07/2003 |
| 6630307 | Method of detecting an analyte in a sample using semiconductor nanocrystals as a detectable label The use of semiconductor nanocrystals as detectable labels in various chemical and biological applications is disclosed. The methods find use for detecting a single analyte, as well as multiple analytes by using more than one semiconductor nanocrystal as ... | 10/07/2003 |
| 6630108 | Optical measuring head, in particular for automatic chemical or biological reaction analyzer An optical measuring head 10 of an automatic chemical or biochemical reaction analyzer comprises a first calorimetric analysis detector 12 controlled by a light source 20 associated to an optic fibre 28 for transmission of the light beam to one of the sid... | 10/07/2003 |
| 6627155 | Combustion furnace system for analyzing elements in a sample The present invention discloses a system for analyzing elements contained in a sample in very slight amounts, such as C, S, O, N, H and the like in materials, such as steel and ceramics. An element analyzer can gasify the sample elements in an appropriate... | 09/30/2003 |
| 6623984 | MEMS-based integrated magnetic particle identification system The present invention provides a MEMS-based integrated particle identification system having a substrate, a magnetic structure, and a bioferrograph. The substrate includes a topside portion, backside portion and a flow system. The flow system includes a f... | 09/23/2003 |
| 6623971 | Method and apparatus for conducting a stat immunoassay analysis in a capsule chemistry analysis system An apparatus and a method for analyzing a plurality of samples according to an analysis protocol is described, wherein each of the samples is contained within a liquid test package comprising a plurality of liquid and air segments including a reagent segm... | 09/23/2003 |
| 6620623 | Biochip reader with enhanced illumination and bioarray positioning apparatus A method of illumination and illumination apparatus are provided in a biochip reader. Illumination is provided by a non-collimated laser source or a light emitting diode (LED). The light is directed to opposing sides of a glass substrate by a pair of opti... | 09/16/2003 |
| 6613282 | Optical-chemical sensor An optical-chemical sensor which is suitable for the continuous and discontinuous determination by luminescence optics of the concentration of chloride in an aqueous sample and which comprises a luminescence indicator (I) and a polymer (H) carrying the lu... | 09/02/2003 |
| 6613212 | Multiple capillary electrophoresis systems The invention concerns a multiple capillary electrophoresis system including many juxtaposed capillaries, at least one source for transmitting a beam designed to excite the molecules present in its path and inside the capillaries, and detection of the flu... | 09/02/2003 |
| 6608671 | Detector and screening device for ion channels The invention provides for a detector assembly, fiber assembly and screening system for optical measurements.... | 08/19/2003 |
| 6605471 | Method and system for determining at least one parameter of at least one sample of a physiological liquid, a holder and a test device The present invention relates to a method for determining at least one parameter of samples of physiological liquids, to test devices which may be used in the method, to a holder comprising a plurality of such test devices, and to a measuring apparatus ad... | 08/12/2003 |
| 6602716 | Method and device for referencing fluorescence intensity signals A method and device for fluorimetric determination of a biological, chemical or physical parameter of a sample utilize at least two different luminescent materials, the first of which is sensitive to the parameter, at least with respect to luminescence in... | 08/05/2003 |
| 6602702 | Detection system based on an analyte reactive particle A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into which a plurality of cavities may be formed. A series of ... | 08/05/2003 |
| 6596544 | Functional assay of high-density lipoprotein This invention provides novel assays that are prognostic and/or diagnostic for atherosclerosis or risk of atherosclerosis. It was discovered that high density lipoprotein (HDL) or components thereof can prevent the oxidation of lipids (e.g. lipids present... | 07/22/2003 |
| 6593155 | Method for determination of cure and oxidation of spin-on dielectric polymers This invention is a method comprising preparing a sample by coating a thin film of a precursor material, which is free of fluorescent probe molecules onto a substrate and subjecting the precursor material to conditions to attempt to cause cure of the prec... | 07/15/2003 |
| 6592821 | Focusing of microparticles in microfluidic systems Methods and systems for particle focusing to increase assay throughput and sensitivity in microscale systems are provided. The invention includes methods for providing substantially uniform flow velocity to flowing particles in microfluidic devices. Metho... | 07/15/2003 |
| 6589731 | Method for detecting biological agents A sensor element is provided including a polymer exhibiting a measurable property from the group of luminescence and electrical conductivity, the polymer being complexed with a unit including a recognition element, a tethering element and a property-alter... | 07/08/2003 |
| 6582658 | Fiber optic moisture sensor A fiber optic moisture sensor is described that can detect the presence or concentration of an analyte in an environment; additionally, a method for making the sensor is described. The invention consists of three primary components: a sensor head, an opti... | 06/24/2003 |
| 6579498 | Implantable blood glucose sensor system An implanted sensing device (1) for monitoring an analyte (e.g. blood-glucose) includes a non-toxic macromolecular material (2) encapsulated within an envelope (3) of bio-compatible semi-permeable membrane. A sensor (4) responds to change of a physical pr... | 06/17/2003 |
| 6579685 | Method and apparatus for screening microscopic cells utilizing light scatter techniques A method for performing screening of one or more cell groups of interest obscured by a cell population such as one or more subsets of interest of a WBC population utilizing at least one light sensing parameter. The cell group of interest is enumerated by ... | 06/17/2003 |
| 6576194 | Sheath flow assembly The present invention provides an apparatus and method for storing a particle-containing liquid. The storage apparatus comprises a microfluidic convoluted flow channel having a plurality of particle capture regions. The storage channel is preferably an is... | 06/10/2003 |
| 6576192 | Fluoroionophores and their use in optical ion sensors Fluoroionophores of formula (I) ##STR1## wherein R06 is H or substituted or unsubstituted C1 -C20 alkyl, R6 is H or substituted or unsubstituted C1 -C30 alkyl or C1 -C30 al... | 06/10/2003 |
| 6572828 | Method and apparatus for high-throughput chemical screening The present invention is directed to a method and apparatus for rapid screening of potential reactants, catalysts, or associated process conditions. In one embodiment, the method includes the steps of providing a reaction substrate having at least one sub... | 06/03/2003 |
| 6569384 | Tissue-based water quality biosensors for detecting chemical warfare agents A water quality sensor for detecting the presence of at least one chemical or biological warfare agent includes: a cell; apparatus for introducing water into the cell and discharging water from the cell adapted for analyzing photosynthetic activity of nat... | 05/27/2003 |
| 6563581 | Scanning system and method for scanning a plurality of samples A system for detecting fluorescence emitted from a plurality of samples in a sample tray is provided. The system generally includes a plurality of lenses positioned in a linear arrangement, a linear actuator configured to translate the plurality of lenses... | 05/13/2003 |
| 6558626 | Vapor sensing instrument for ultra trace chemical detection A detector for detecting vapors emitted from energetic compounds includes a housing, a pump and a sensing assembly. The housing has an inlet, an outlet and an enclosed sensing volume there between. The pump communicates with the housing for moving a carri... | 05/06/2003 |
| 6558958 | Optical fiber evanescent field excited fluorosensor and method of manufacture An optical fiber is tapered, preferably adiabatically, and has a material coated on it for chemical bonding with fluorophores. When the fluorophores couple with the material, evanescent radiation generated fibers causes the fluorophores to fluoresce, and ... | 05/06/2003 |
| 6555060 | Apparatus for performing diagnostic testing The present invention relates to a hand-held diagnostic testing system and method employing apparatus that can effect a chemiluminescent reaction and record the same on photographic film.... | 04/29/2003 |
| 6555387 | Method for producing thin liquid samples for microscopic analysis The present invention relates to the field of diagnostics by means of microscopic sample analysis, and specifically relates to a method and apparatus for preparing thin microscopic samples of liquids, and in particular monolayers of red blood cells.... | 04/29/2003 |
| 6548263 | Miniaturized cell array methods and apparatus for cell-based screening The present invention describes novel methods for making a substrate for selective cell patterning, and the substrates themselves, wherein the method comprises contacting reactive hydroxyl groups on the surface of a substrate with a hydroxyl-reactive bifu... | 04/15/2003 |
| 6548018 | Apparatus for chemiluminescent assays Disclosed herein is a device and methods for the rapid chemiluminescence assay of surfaces to detect the presence of microbial contamination. The device and methods are suitable for use by untrained personnel under the relatively harsh and variable condit... | 04/15/2003 |
| 6544795 | Method and apparatus for rapid determination of fries rearrangement products in aromatic polycarbonate resins A rapid analysis method for the determination of Fries rearrangement products in aromatic polycarbonate resins utilizes in-line determination of polymer concentration and in-line fluorescence detection of Fries rearrangement products. The method avoids ti... | 04/08/2003 |
| 6544729 | Bioluminescent biosensor device Disclosed are methods and devices for detection of bacteria based on recognition and infection of one or more selected strains of bacteria with bacteriophage genetically modified to cause production of an inducer molecule in the bacterium following phage ... | 04/08/2003 |
