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Patent No. 6099319

Neuroimaging as a Marketing Tool

Neuroimaging as a means for validating whether a stimulus such as advertisement, communication, or product evokes a certain mental response such as emotion, preference, or memory, or to predict the consequences of the stimulus on later behavior such as consumption or purchasing.

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Class 422/82.08 - Fluorescence


Subclass of Class 422 - Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing
Definition: Apparatus having means for measuring fluorescence or luminescence
No. of patents: 859
Last issue date: 04/10/2012


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NumberTitleIssue Date
8153064Systems and devices for isothermal biochemical reactions and/or analysis
An isothermal reaction and analysis system may include a receiver to receive sample holders, a thermal control subsystem to control a temperature of the receiver, an excitation subsystem, a detection subsystem and an analysis subsystem. Excitation sources and/or det...
04/10/2012
8153065Flourescent organic nanofibrils based on arylene-ethylene macrocycles as sensory materials for explosives detection
The present invention relates to a class of fluorescent, organic nanofibrils, and particularly the films comprising entangled piling of these nanofibrils exhibiting effective quenching of their fluorescence upon exposure the vapor of explosives. The invention also r...
04/10/2012
8084001Photoluminescent silica-based sensors and methods of use
Sensor particles comprise a silica-based core and at least one photoluminescent dye. The silica-based core may comprise a plurality of pores and the at least one photoluminescent dye may comprise a reference dye, insensitive to its environment and analytes and a sen...
12/27/2011
8075841Biosensor with one-dimensional sub-diffraction-limited apertures composed of a grid and a polarizer
A method and sensor for the detection of luminescence radiation generated by at least one luminophore is disclosed. In the context of the present invention the biosensor comprises a grid (120) defined as arrays of apertures with the apertures having a first d...
12/13/2011
7998414System for high throughput GPCR functional assay
A functional assay detection system for membrane bound proteins. The system comprises a biological array including a porous substrate having a plurality of membranes adhered thereto and a first side and a second side, a fluorescent labeling reagent configured to cou...
08/16/2011
7988918Structures for enhanced detection of fluorescence
Substrates are provided for use in the detection, identification and analysis of biologic or chemical samples that are labeled with a fluorescent label, in which the plane of maximum fluorescence is displaced from a reflective substrate surface so that the intensity...
08/02/2011
7939023Assay apparatus and sensor holding method
A sensor unit is retained on an assay stage of a surface plasmon resonance (SPR) assay apparatus. The sensor unit includes a prism having a sensing surface, disposed on an upper surface thereof, for detecting reaction of a sample. A flow cell is secured to the upper...
05/10/2011
7935309Multi-transduction mechanism based microfluidic analyte sensors
In various aspects are provided a microfluidic and/or nanofluidic sensor that can provide an indication of the reliability of its measurement of the presence of an analyte in a sample under investigation, an analyte concentration in the sample under investigation, o...
05/03/2011
7931867Uniform surfaces for hybrid material substrates and methods for making and using same
Devices, systems and methods of using same where hybrid substrate materials are provided with a substantially uniform surface to provide uniformity of properties, including interaction with their environments. Uniform surfaces are applied as coatings over, e.g., hyb...
04/26/2011
7927547Reagentless and reusable biosensors with tunable differential binding affinities and methods of making
The biosensor comprises a modular biorecognition element and a modular flexible arm element. The biorecognition element and the flexible arm element are each labeled with a signaling element. The flexible arm contains an analog of an analyte of interest that binds w...
04/19/2011
7897109Oxygen monitoring apparatus
Apparatus or systems which employ luminescence quenching to produce an oxygen concentration indicative signal. Components of such systems include: (1) an airway adapter, sampling cell, or the like having a sensor which is excited into luminescence with the luminesce...
03/01/2011
7871573Enhancement of sensitivity of fluorophore mediated biosensing and bioimaging
A method of enhancing fluorescence emission in a fluorophore-mediated sensing, biosensing, imaging, and bioimaging. An example of biosensing is a fluorophore-mediated sandwich immunoassay with a 1° monoclonal antibody against a target analyte and a fluorophore-link...
01/18/2011
7846391Bioanalytical instrumentation using a light source subsystem
The invention relates to a light source for irradiating molecules present in a detection volume with one or more selected wavelengths of light and directing the fluorescence, absorbance, transmittance, scattering onto one or more detectors. Molecular interactions wi...
12/07/2010
7794661Method and system for detecting fluorescence from microarray disk
In a fluorescence detection method: each of one or more biological specimens is irradiated with excitation light while a substrate disk is rotated, where the one or more biological specimens are labeled with a fluorescent material and fixed on the substrate disk. Fl...
09/14/2010
7785536Photon reducing agents for fluorescence assays
The present invention provides a method for reducing undesirable light emission from a sample using at least one photon producing agent and at least one photon reducing agent (e.g. dye-based photon reducing agents). The present invention further provides a method fo...
08/31/2010
7736590Method for measuring oxygen amount in hermetically sealed container and piercing device for hermetically sealed container used therefore
A method to efficiently measure the oxygen content of both the headspace and fluid within a hermetically sealed container. A container is pierced using a hollow needle with the interior space sealed from the outside and the tip of said hollow needle removed, and the...
06/15/2010
7718131Methods and apparatus for imaging and processing of samples in biological sample containers
Disclosed herein is a holder for biological sample containers such as well plates. The holder comprises a flat vacuum bed surrounded by a seal. A container is placed within the seal and a vacuum is applied, pressing and flattening the lower surface of the sample con...
05/18/2010
7591979Enhanced monitor system for water protection
An automatic, self-contained device for detecting toxic agents in a water supply includes an analyzer for detecting at least one toxic agent in a water sample, introducing means for introducing a water sample into the analyzer and discharging the water sample from t...
09/22/2009
7585466Automatic genotype determination
Genotypes of a subject may be determined by analyzing a biological sample. Measurements of the intensity of allele specific signals may be obtained and used to generate reaction values. These reaction values may be compared to probability distributions in order to o...
09/08/2009
7449151Fluorescence resonance energy transfer analyzer
An analyzer for measuring an FRET (fluorescence resonance energy transfer) efficiency of a specimen containing a donor and an acceptor. The analyzer has an illuminator, an optical system, a detector and a calculator. The illuminator emits light for donor excitation ...
11/11/2008
7435386Reagentless and reusable biosensors with tunable differential binding affinities and methods of making
The biosensor comprises a modular biorecognition element and a modular flexible arm element. The biorecognition element and the flexible arm element are each labeled with a signaling element. The flexible arm contains an analog of an analyte of interest that binds w...
10/14/2008
7435602Reducing effects of spectral nonuniformity
Method and system providing calibration of light detected from biological samples with a correction factor including components for each of a plurality of spectrally distinguishable species and/or for each well and/or for each filter. ...
10/14/2008
7427378Analysis method and apparatus for sulfur component using ultraviolet fluorescence
An analysis method and analysis apparatus involve analysis for a sulfur component using ultraviolet fluorescence capable of removing the interferential influence of NO with good efficiency and certainty to thereby measure a concentration of only sulfur components su...
09/23/2008
7423753Fiber optical sensor with optical resonator
A fiber optical sensor includes a light source, a detector and an optical resonator having a multimode optical fiber and two reflective layers respectively provided adjacent to or on ends of the optical fiber. Excitation light from the light source is coupled into t...
09/09/2008
7423750Configurations, systems, and methods for optical scanning with at least one first relative angular motion and at least one second angular motion or at least one linear motion
Methods and optical systems for scanning of a target sample, including methods and systems using a low mass scan head and methods and systems for conducting a scanned optically transduced assay where the scanning includes at least one first relative angular motion a...
09/09/2008
7419636Vapor sensing instruments for ultra trace chemical detection
A detector for detecting vapors emitted from analytes includes a housing, a pump and a sensing assembly. The housing has an inlet, an outlet and an enclosed sensing volume therebetween. The pump communicates with the housing for moving a carrier sequentially through...
09/02/2008
7419836Device and method for observing reactions in samples
The present invention relates to a device (1) for observing reactions in samples (2), to which a reagent (3) is added, and/or a method which is based on the use of this device. The device includes at least one first optical device (4) for...
09/02/2008
7419834System for detection of nitrosylated proteins
The present invention describes a novel, simplified method for detecting and monitoring whether the presence of nitrosylated proteins, such as S-nitrosoproteins, in a biological sample using fluorescence detection. The present invention further describes a method wh...
09/02/2008
7416701Calibrator for fluorosensor
A multichannel fluorosensor includes an optical module and an electronic module combined in a watertight housing with an underwater connector. The fluorosensor has an integral calibrator for periodical sensitivity validation of the fluorosensor. The optical module h...
08/26/2008
7416703Polymer based lanthanide luminescent sensors for the detection of organophosphorus compounds
A device for measuring and detecting the organophosphonis compounds, such as a pesticides or a nerve agents is provided. The devices function by selectively binding an organophosphorous compound to a luminescent functionality-imprinted copolymer. The copolymers poss...
08/26/2008
7416902Method and apparatus for airborne particle sorting
An apparatus for airborne particle sorting is provided comprising a charging system adapted for applying an electrostatic charge to the particles, such that particles of at least a first group are deflected to a greater extent than particles of a second group are de...
08/26/2008
7416700Immunoassay fluorometer
A fluorometer for sensing the fluorescence of a sample utilizes an optical energy source for exciting a sample to be tested and an optical energy detector for detecting the emitted energy from the excited sample. Drive electronics are used for positioning the sample...
08/26/2008
7410793Optical instrument including excitation source
An optical instrument is provided for simultaneously illuminating two or more spaced-apart reaction regions with excitation beams generated by a light source. The light source can include an area light array of light emitting diodes, one or more solid state lasers, ...
08/12/2008
7410809Particle or cell analyzer and method
A particle analyzer in which tagged particles to be analyzed are drawn through a suspended capillary tube where a predetermined volume in the capillary tube is illuminated. The illumination scattered by said particles is detected by a detector to count all particles...
08/12/2008
7407796Interrogation of changes in the contents of a sealed container
A device and method allowing evaluation of the contents of a sealed primary container by means of an integral sensor which is separated from the contents of the sealed primary container yet provides information on quality of the contents of the primary container wit...
08/05/2008
7405082Methods and devices for measuring reticulocytes
Methods and devices are described for monitoring a therapeutic effect in a red blood cell-related disease by detecting the size of a reticulocyte using a full-automatic blood cell counting device. ...
07/29/2008
7399445Chemical sensor
A sensor device is formed from a metal film having a plurality of openings, a sensor material positioned within each of the openings, a light source that emits light having a first wavelength, and a light detector that detects light emitted from the light source and...
07/15/2008
7393442Ex-situ PEM fuel cell testing: towards visualizing gas diffusion
The invention comprises novel apparatuses and testing methods for evaluating a fluid diffusion component. The apparatus includes a fluid capable of undergoing oxidation or reduction, a half-cell electrode assembly able to receive the fluid, and a change in acidity i...
07/01/2008
7390462Ratiometric fluorescent pH sensor for non-invasive monitoring
The present invention provides ratiometric fluorescent pH sensors for non-invasive, continuous monitoring of pH in such applications as fermentation processes. The ratiometric fluorescent pH sensors comprise a fluorescent dye that exhibits a shift in excitation wave...
06/24/2008
7387891Optical instrument including excitation source
An optical instrument is provided for simultaneously illuminating two or more spaced-apart reaction regions with an excitation beam generated by a light source. A collimating lens can be disposed along a beam path between the light source and the reaction regions to...
06/17/2008
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