...Daniel Webster invented a "bull plow" to pull out tree stumps. It didn't catch on because it was huge and required four oxen to pull it!
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| Number | Title | Issue Date |
| 8137626 | Fluorescence detector, filter device and related methods Microfluidic assay detectors and microfluidic assay detection methods are disclosed. A microfluidic chip is coupled to a light emitting device, emission filters and excitation filters. Excited fluorescent light is detected by a camera and a lens. The correspondent r... | 03/20/2012 |
| 8038947 | Analyte sensor devices and holders, and methods and systems utilizing the same Provided are sensor devices, methods, systems, and kits for measuring the concentration of at least one target analyte. Sensor devices may be mounted into an optical system for measuring the target analyte. Example sensor devices may also be removably mounted in a h... | 10/18/2011 |
| 8038946 | Discreet passive explosive detection through 2-sided waveguided fluorescence The current invention provides a passive sampling device suitable for collecting and detecting the presence of target analytes. In particular, the passive sampling device is suitable for detecting nitro-aromatic compounds. The current invention further provides a pa... | 10/18/2011 |
| 7897108 | Sensor and method of sensing having an energy source and detector on the same side of a sensor substance A sensor has a sensor substance, an electromagnetic energy source, and a detector. The sensor substance may be able to emit electromagnetic energy different than that provided by the energy source when an analyte of interest is in contact with the sensor substance a... | 03/01/2011 |
| 7833480 | Oxygen monitoring apparatus and methods of using the apparatus Apparatus or systems which employ luminescence-quenching to produce a signal indicative of oxygen concentration. Components of such systems include: (1) an airway adapter, sampling cell, or the like having a casing and a sensor which is excited into luminescence wit... | 11/16/2010 |
| 7718130 | Integrated thin-film sensors and methods Integrated photoluminescence (PL)-based chemical and biological sensors are provided comprising a photodetector (PD), a long-pass filter, an excitation source, and a sensing element, all based on thin films or structures. In one embodiment the light source is an org... | 05/18/2010 |
| 7438853 | Photoelectrocatalytic method and photoelectrochemical detector for electrochemical analysis A photoelectrocatalytic method for detecting current that illuminates a photoelectrochemical electrode to generate a photocurrent and to magnify the current. Thereby, accuracy of the detection is increased. A photoelectrochemical detector used in the method has a ba... | 10/21/2008 |
| 7435386 | Reagentless and reusable biosensors with tunable differential binding affinities and methods of making The biosensor comprises a modular biorecognition element and a modular flexible arm element. The biorecognition element and the flexible arm element are each labeled with a signaling element. The flexible arm contains an analog of an analyte of interest that binds w... | 10/14/2008 |
| 7419636 | Vapor sensing instruments for ultra trace chemical detection A detector for detecting vapors emitted from analytes includes a housing, a pump and a sensing assembly. The housing has an inlet, an outlet and an enclosed sensing volume therebetween. The pump communicates with the housing for moving a carrier sequentially through... | 09/02/2008 |
| 7416701 | Calibrator for fluorosensor A multichannel fluorosensor includes an optical module and an electronic module combined in a watertight housing with an underwater connector. The fluorosensor has an integral calibrator for periodical sensitivity validation of the fluorosensor. The optical module h... | 08/26/2008 |
| 7416703 | Polymer based lanthanide luminescent sensors for the detection of organophosphorus compounds A device for measuring and detecting the organophosphonis compounds, such as a pesticides or a nerve agents is provided. The devices function by selectively binding an organophosphorous compound to a luminescent functionality-imprinted copolymer. The copolymers poss... | 08/26/2008 |
| 7402426 | Detection of biological molecules by differential partitioning of enzyme substrates and products This invention relates to a method and apparatus for detecting a biological molecule associated with enzyme activity in a sample. The invention is applicable to detecting a microorganism associated with an enzyme in a sample such as water, food, soil, or a biologica... | 07/22/2008 |
| 7399446 | Apparatus and process for locating and for measuring variations in temperature and/or in degree of fouling over the internal surface of equipment The present invention relates to an apparatus and a process for locating and for measuring variations in temperature and/or in degree of fouling over the internal suface of equipment. ... | 07/15/2008 |
| 7399445 | Chemical sensor A sensor device is formed from a metal film having a plurality of openings, a sensor material positioned within each of the openings, a light source that emits light having a first wavelength, and a light detector that detects light emitted from the light source and... | 07/15/2008 |
| 7393442 | Ex-situ PEM fuel cell testing: towards visualizing gas diffusion The invention comprises novel apparatuses and testing methods for evaluating a fluid diffusion component. The apparatus includes a fluid capable of undergoing oxidation or reduction, a half-cell electrode assembly able to receive the fluid, and a change in acidity i... | 07/01/2008 |
| 7384606 | Bead dispensing system A bead dispensing system is provided for delivering small amounts of substances onto substrates. The system can include, for example, a movable support structure having an array of spaced-apart projections depending from its lower side. An attraction source, such as... | 06/10/2008 |
| 7384795 | Methods for verifying fluid movement Methods for using semiconductor nanocrystals for determining fluid movement, fluid dilution and fluid removal are described. Methods for using semiconductor nanocrystals for monitoring and quantifying the amounts of solid materials dissolved in a liquid are also des... | 06/10/2008 |
| 7371247 | Method and apparatus for penetrating tissue A tissue penetrating system includes a plurality of penetrating members each having a tip. A penetrating member driver is coupled to the plurality of penetrating members. Each tip of a penetrating member is uncovered during launch of the penetrating member by the pe... | 05/13/2008 |
| 7351374 | Surface plasmon enhanced illumination apparatus having non-periodic resonance configurations An apparatus configured to generate surface plasmon enhanced radiation comprises a metal film having first and second surfaces, and one or more resonance configurations formed in the metal film. An exemplary resonance configuration includes an aperture extending bet... | 04/01/2008 |
| 7348181 | Self-encoding sensor with microspheres A microsphere-based analytic chemistry system is disclosed in which self-encoding microspheres having distinct characteristic optical response signatures to specific target analytes may be mixed together while the ability is retained to identify the sensor type and ... | 03/25/2008 |
| 7338778 | Luminescent method for determining cell oxygen consumption The present invention relates to methods for detection and evaluation of metabolic activity of eukaryotic and/or prokaryotic cells based upon their ability to consume dissolved oxygen. The methods utilize a luminescence detection system which makes use of the sensit... | 03/04/2008 |
| 7331931 | Method and apparatus for penetrating tissue These and other objects of the present invention are achieved in a body fluid sampling system for use on a tissue site that includes an electrically powered drive force generator. A penetrating member is operatively coupled to the force generator. The force generato... | 02/19/2008 |
| 7329388 | Electrophoresis apparatus having staggered passage configuration An electrophoresis apparatus is generally disclosed for sequentially analyzing a single sample or multiple samples having one or more analytes in high or low concentrations. The apparatus comprises a relatively large-bore transport capillary which intersects with a ... | 02/12/2008 |
| 7319522 | Systems and methods for in situ spectroscopic measurements A circularizated semiconductor laser diode (CSLD), such as for example a vertical cavity surface emitting laser (VCSEL) may be used for optical measurements. The CSLD may be used in a cell density probe to perform cell density determination and/or turbidity determin... | 01/15/2008 |
| 7318907 | Surface plasmon enhanced illumination system Methods and apparatus for producing small, bright nanometric light sources from apertures that are smaller than the wavelength of the emitted light. Light is directed at a surface layer of metal onto a light barrier structure that includes one or more apertures each... | 01/15/2008 |
| 7318909 | Method and apparatus for enhanced evanescent field exposure in an optical fiber resonator for spectroscopic detection and measurement of trace species An apparatus for detection and measurement of trace species in a gas or liquid sample. A sensor of a ring down cell formed from an optical fiber is exposed to the sample gas or liquid. A coherent source emits radiation into the optical fiber loop, which in turn is r... | 01/15/2008 |
| 7316700 | Self optimizing lancing device with adaptation means to temporal variations in cutaneous properties A lancing device, an embodiment of which controls the advancement and retraction of a lancet by monitoring the position of the lancet in conjunction with a lancet controller which incorporates a feedback loop for modulating the lancet driver to follow a predetermine... | 01/08/2008 |
| 7314751 | Fluorescence detection system including a photonic band gap structure A fluorescence detection system includes a photonic band gap structure. An internal surface of the photonic band gap structure defines a core region, and is coated with a film formed of conjugated polymer molecules. The core region is filled with a sample fluid or g... | 01/01/2008 |
| 7309568 | Method in inspecting DNA and apparatus therefor A method and apparatus of stably obtaining fluorescent images of two or more fluorescent samples includes disposing the samples onto compartments defined on a substrate. The compartments are sequentially irradiated with an exciting light where the intensity varies. ... | 12/18/2007 |
| 7305154 | Energetic atomic and ionic oxygen textured optical surfaces for blood glucose monitoring Disclosed is a method and the resulting product thereof comprising a solid light-conducting fiber with a point of attachment and having a textured surface site consisting a textured distal end prepared by being placed in a vacuum and then subjected to directed hyper... | 12/04/2007 |
| 7300197 | Apparatus for dissolving a solid material in a liquid An apparatus for dissolving a solid material in a liquid including a container for receiving the solid material and the liquid. A turbidimeter measures the turbidity of the liquid in the container. A blender stirs the liquid in the container until the turbidity ther... | 11/27/2007 |
| 7294287 | Quinophenanthrine diones fluorescent whitening agents Tetrahydro- and dihydroquinophenanthrine dione fluorescent whitening agents and a process for their preparation are provided. ... | 11/13/2007 |
| 7291504 | Assay involving detection and identification with encoded particles A method and apparatus for the manipulation of colloidal particles and biomolecules at the interface between an insulating electrode such as silicon oxide and an electrolyte solution. Light-controlled electrokinetic assembly of particles near surfaces relies on the ... | 11/06/2007 |
| 7291117 | Method and apparatus for penetrating tissue These and other objects of the present invention are achieved in a body fluid sampling system for use on a tissue site that includes a voice coil based penetrating member driver. A plurality of penetrating members are included. A transport mechanism is configured to... | 11/06/2007 |
| 7280201 | Sensor having integrated light detector and/or light source A sensor, such as a lateral flow sensor, which includes a chemical layer and a detector on a flexible substrate. An optical signal is produced in response to an analyte placed on the chemical layer. The detector detects the signal, to thereby detect the presence, ab... | 10/09/2007 |
| 7271249 | Biosensors, method for obtaining the same and uses thereof The invention relates to biosensors, methods for obtaining them and their use fro detecting, assaying or locating, in direct immunofluorescence, a ligand such as an antigen or hapten, in a heterogeneous population. The biosensor includes (i) at least one fragment of... | 09/18/2007 |
| 7271009 | Multi-analyte diagnostic test for thyroid disorders Immunological assays for several biological markers for thyroid disorders in a biological sample are performed in a single test with a combination of sandwich-type, sequential competitive, and serological assays by the use of particles classified into groups that ar... | 09/18/2007 |
| 7270970 | Point of care diagnostic systems Systems and methods for medical diagnosis or risk assessment for a patient are provided. These systems and methods are designed to be employed at the point of care, such as in emergency rooms and operating rooms, or in any situation in which a rapid and accurate res... | 09/18/2007 |
| 7267797 | Nanofabricated photon tunneling based sensor A system and method for detecting changes in the refractive index of a fluid in a small test volume. A change in the refractive index can indicate a change in the chemical composition of the fluid. The test volume has a depth comparable to or less than the wavelengt... | 09/11/2007 |
| 7264971 | Read-head for optical diagnostic device A readhead for a photometric diagnostic instrument includes a housing adapted for incorporation within the photometric diagnostic instrument, and an elongated sample table operatively engaged with the housing. The sample table is configured to support elongated reag... | 09/04/2007 |