...that Kleenex tissue was originally designed to be a gas mask filter? It was developed at the beginning of World War I to replace cotton, which was then in short supply as a surgical dressing.
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| Number | Title | Issue Date |
| 8105539 | Chemical sensor for hydrazine Chemical sensors whose active element exhibits both a visual change in color and a measurable change in electrical resistance when exposed to an analyte to which it selectively reacts are provided. These sensor have several unique features including vastly improved ... | 01/31/2012 |
| 7910065 | Reaction sensing in living cells Chemical reactions occurring within a living cell are measured in a manner that does not affect the viability of the cell or the reaction under study. In one embodiment, one or more sensors are introduced into the cell and/or covalently associated with the exterior ... | 03/22/2011 |
| 7521019 | Sensor device and methods for manufacture The present invention provides a device and methods for detecting the presence of an analyte in a sample using an encapsulated sensor. Methods for manufacturing the sensor are also disclosed. ... | 04/21/2009 |
| 7435386 | Reagentless and reusable biosensors with tunable differential binding affinities and methods of making The biosensor comprises a modular biorecognition element and a modular flexible arm element. The biorecognition element and the flexible arm element are each labeled with a signaling element. The flexible arm contains an analog of an analyte of interest that binds w... | 10/14/2008 |
| 7419636 | Vapor sensing instruments for ultra trace chemical detection A detector for detecting vapors emitted from analytes includes a housing, a pump and a sensing assembly. The housing has an inlet, an outlet and an enclosed sensing volume therebetween. The pump communicates with the housing for moving a carrier sequentially through... | 09/02/2008 |
| 7416701 | Calibrator for fluorosensor A multichannel fluorosensor includes an optical module and an electronic module combined in a watertight housing with an underwater connector. The fluorosensor has an integral calibrator for periodical sensitivity validation of the fluorosensor. The optical module h... | 08/26/2008 |
| 7413893 | Methods, apparatus and compositions for improved measurements with optical biosensors The invention provides an apparatus for interrogating an optical biosensor. The apparatus includes (a) locating means for positioning one or more optical biosensors; (b) calibration means for generating a reference measurement; (c) one or more biosensors for generat... | 08/19/2008 |
| 7402426 | Detection of biological molecules by differential partitioning of enzyme substrates and products This invention relates to a method and apparatus for detecting a biological molecule associated with enzyme activity in a sample. The invention is applicable to detecting a microorganism associated with an enzyme in a sample such as water, food, soil, or a biologica... | 07/22/2008 |
| 7399446 | Apparatus and process for locating and for measuring variations in temperature and/or in degree of fouling over the internal surface of equipment The present invention relates to an apparatus and a process for locating and for measuring variations in temperature and/or in degree of fouling over the internal suface of equipment. ... | 07/15/2008 |
| 7399445 | Chemical sensor A sensor device is formed from a metal film having a plurality of openings, a sensor material positioned within each of the openings, a light source that emits light having a first wavelength, and a light detector that detects light emitted from the light source and... | 07/15/2008 |
| 7382458 | Fiber optic fluid probe A fiber optic fluid probe is employed in determining characteristics of a fluid or solid dispersed in the fluid into which the probe is immersed. The probe transmits electromagnetic radiation from a source by way of one or more fiber optic fibers and into the fluid,... | 06/03/2008 |
| 7358476 | Sensing photons from objects in channels A fluidic structure includes a channel and along the channel is a series of sensing components to obtain information about objects traveling within the channel, such as droplets or other objects carried by fluid. At least one sensing component includes a set of cell... | 04/15/2008 |
| 7356365 | Method and apparatus for tissue oximetry In accordance with the invention, the oxygenation of blood-profused tissue is measured by shining light into the profused tissue and analyzing the light reflected within the tissue. The light is reflected by cell walls in the tissue and is partially absorbed by hemo... | 04/08/2008 |
| 7348181 | Self-encoding sensor with microspheres A microsphere-based analytic chemistry system is disclosed in which self-encoding microspheres having distinct characteristic optical response signatures to specific target analytes may be mixed together while the ability is retained to identify the sensor type and ... | 03/25/2008 |
| 7338778 | Luminescent method for determining cell oxygen consumption The present invention relates to methods for detection and evaluation of metabolic activity of eukaryotic and/or prokaryotic cells based upon their ability to consume dissolved oxygen. The methods utilize a luminescence detection system which makes use of the sensit... | 03/04/2008 |
| 7332128 | Fiber-optic dissolution systems devices, and methods A dissolution system provides remote flow cells integrated into a manifold device. The manifold device communicates with liquid input and output lines associated with each flow cell, as well as fiber-optic input and output lines associated with each flow cell. Liqui... | 02/19/2008 |
| 7318909 | Method and apparatus for enhanced evanescent field exposure in an optical fiber resonator for spectroscopic detection and measurement of trace species An apparatus for detection and measurement of trace species in a gas or liquid sample. A sensor of a ring down cell formed from an optical fiber is exposed to the sample gas or liquid. A coherent source emits radiation into the optical fiber loop, which in turn is r... | 01/15/2008 |
| 7291824 | Photosensing throughout energy range and in subranges An integrated circuit (IC) includes a photosensor array, some cells of which are reference cells that photosense throughout an application's energy range, while other cells of which are subrange cells that photosense within respective subranges. For example, the sub... | 11/06/2007 |
| 7288227 | Biochip reader with enhanced illumination and bioarray positioning apparatus A method of illumination and illumination apparatus are provided in a biochip reader. Illumination is provided by a non-collimated laser source or a light emitting diode (LED). The light is directed to opposing sides of a glass substrate by a pair of optical fiber b... | 10/30/2007 |
| 7283245 | Handheld device with a disposable element for chemical analysis of multiple analytes A portable system and method for measuring the concentration of multiple chemical or biological substances where an onsite analysis of such substances is needed. The new and original handheld sensor system uses a disposable optical test element and a spectroscopic d... | 10/16/2007 |
| 7271249 | Biosensors, method for obtaining the same and uses thereof The invention relates to biosensors, methods for obtaining them and their use fro detecting, assaying or locating, in direct immunofluorescence, a ligand such as an antigen or hapten, in a heterogeneous population. The biosensor includes (i) at least one fragment of... | 09/18/2007 |
| 7270970 | Point of care diagnostic systems Systems and methods for medical diagnosis or risk assessment for a patient are provided. These systems and methods are designed to be employed at the point of care, such as in emergency rooms and operating rooms, or in any situation in which a rapid and accurate res... | 09/18/2007 |
| 7267797 | Nanofabricated photon tunneling based sensor A system and method for detecting changes in the refractive index of a fluid in a small test volume. A change in the refractive index can indicate a change in the chemical composition of the fluid. The test volume has a depth comparable to or less than the wavelengt... | 09/11/2007 |
| 7264971 | Read-head for optical diagnostic device A readhead for a photometric diagnostic instrument includes a housing adapted for incorporation within the photometric diagnostic instrument, and an elongated sample table operatively engaged with the housing. The sample table is configured to support elongated reag... | 09/04/2007 |
| 7254429 | Method and apparatus for monitoring glucose levels in a biological tissue In accordance with the invention, a low coherence interferometer is used to non-invasively monitor the concentration of glucose in blood by shining a light over a surface area of human or animal tissue, continuously scanning the light over a two dimensional area of ... | 08/07/2007 |
| 7247489 | Ion-detecting microspheres and methods of use thereof This invention provides methods of using ion-detecting microspheres containing an ionphore and a chromoionphore in clinical laboratory instrumentation such as flow cytometry for sample analysis. In one embodiment, the microspheres are contacted with a flowing stream... | 07/24/2007 |
| 7247493 | Reusable pH sensor device and related methods The present invention relates to devices, methods, and kits for quickly and easily measuring and monitoring the pH of aquatic environments, such as lakes, streams, drinking waters, fisheries, aquariums, pools, hot-tubs, and spas. The current invention includes devic... | 07/24/2007 |
| 7238477 | Methods to increase nucleotide signals by Raman scattering The methods and apparatus disclosed herein concern nucleic acid sequencing by enhanced Raman spectroscopy. In certain embodiments of the invention, nucleotides are covalently attached to Raman labels before incorporation into a nucleic acid. In other embodiments, un... | 07/03/2007 |
| 7226563 | Ion-detecting sensors comprising plasticizer-free copolymers Plasticizer-free ion-detecting sensors for detecting a target ion in a sample are provided. The sensor comprises a plasticizer-free copolymer comprised of polymerized units of methacrylate monomers and a polymerizable ion exchanger, wherein the methacrylated monomer... | 06/05/2007 |
| 7220597 | Assay test device and method of making same In accordance with certain disclosed embodiments of the present invention, there is provided an assay test device for determining whether a fluid under test contains a certain substance, wherein the device includes a test strip disposed at least partially within a h... | 05/22/2007 |
| 7221453 | Optical apparatus Various optical apparatus provide a source of parallel light (7, 75). The parallel light (7, 75) is generally achieved by directing an incident beam at the apex of a prism (1, 22, 24, 26, 28). The prism may have varying configurations. One confi... | 05/22/2007 |
| 7214538 | Device and method for the determination of lithium ion concentration in a biological fluid The present invention relates to a novel device and method for the detection of lithium ions in a biological fluid. In a preferred embodiment, the present invention provides a novel compound and a optical sensor which incorporates said compound for the detection of ... | 05/08/2007 |
| 7214543 | Method and apparatus for sensing nitroaromatics The subject invention pertains to a method and apparatus for sensing nitroaromatics. The subject invention can utilize luminescent, for example fluorescent and/or electroluminescent, aryl substituted polyacetylenes and/or other substituted polyacetylenes which are l... | 05/08/2007 |
| 7214346 | Optoelectronic detection system The invention relates to optoelectronic systems for detecting one or more target particles. The system includes a reaction chamber, a specimen collector, an optical detector, and a reservoir containing cells, each of the cells having receptors which are present on t... | 05/08/2007 |
| 7208121 | Plasticizer-free-ion-detective sensors A plasticizer-free ion detective sensor for detecting a target ion in a sample is provided. The sensor comprises a copolymer of methacrylate monomers with pendant alkyl groups of different length, and an ionophore for detecting the target ion. The copolymer matrix o... | 04/24/2007 |
| 7209605 | Packaged optical sensors on the side of optical fibers The present invention concerns an optical sensor located on a preferred azimuthal portion of the side of an optical fiber. An optical fiber having two opposite ends, a core and a cladding and at least one sensing area is disclosed. Each of the sensing areas is locat... | 04/24/2007 |
| 7201876 | Ion-detecting sensors comprising plasticizer-free copolymers Ion-detecting sensors for detecting a target ion in a sample are provided. The sensor comprises a plasticizer-free copolymer comprised of polymerized units of methacrylate monomers having pendent alkyl groups of different length and a functionalized ionophore of sai... | 04/10/2007 |
| 7198755 | Multichannel fluorosensor A multichannel fluorosensor includes an optical module and an electronic module combined in a watertight housing with an underwater connector. The fluorosensor has an integral calibrator for periodical sensitivity validation of the fluorosensor. The optical module h... | 04/03/2007 |
| 7189354 | Optically and fluidically enhanced in vitro diagnostic test chamber An enclosed chamber is used in a system for screening of a liquid specimen through binding assays. The enclosed chamber includes an inlet, an outlet, and a plurality of discrete reactant containing wells communicated by a common reagent flow path between the inlet a... | 03/13/2007 |
| 7189361 | Analytical device with lightguide Illumination of capillary and microgrooves arrays An analytical cell including a lightguide with a plurality of conduits filled with a migration medium. The medium, the lightguide and a surrounding medium have refractive indices selected such that light entering the lightguide is internally reflected within the lig... | 03/13/2007 |