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Thomas Edison ; 1889
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| Number | Title | Issue Date |
| 7387898 | Apparatus and method for conducting assays A multi-well assay plate structure (54) and assay apparatus and a method for performing chemical biochemical assays is described. The multi-well assay plate structure (54) defines a relatively shallow substantially enclosed space (71) above a pl... | 06/17/2008 |
| 7387892 | Biosensor using microdisk laser A compact sensor for detecting the presence of biological or chemical species includes a microdisk laser and a wavelength shift detector. The microdisk laser is coated with a biological or chemical recognition element, which binds preferentially with a target analyt... | 06/17/2008 |
| 7384791 | Method of analyzing blood A method of analyzing blood includes delivering a blood sample to a test device, applying a spatially varying electric field to the blood sample to provide a depleted cell concentration in a portion of the blood sample, and sensing a property of the portion of the b... | 06/10/2008 |
| 7384795 | Methods for verifying fluid movement Methods for using semiconductor nanocrystals for determining fluid movement, fluid dilution and fluid removal are described. Methods for using semiconductor nanocrystals for monitoring and quantifying the amounts of solid materials dissolved in a liquid are also des... | 06/10/2008 |
| 7381370 | Automated multi-detector analyzer An automated analyzer for analyzing patient samples. The analyzer includes a plurality of cuvettes, which allow the samples to be mixed with various reagents. The analyzer includes one or more detectors, including a detector adapted to detect luminescence of the rea... | 06/03/2008 |
| 7381565 | Flow cytometers and detection system of lesser size Gas focusing flow cytometers are fabricatable employing simple and inexpensive manufacturing techniques. When such cytometers or conventional cytometers are combined with fiber optical light paths and laser diode and semiconductor photodetectors, light weight and ha... | 06/03/2008 |
| 7381570 | Device and method for multiple analyte detection The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more of a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurali... | 06/03/2008 |
| 7381569 | Device and method for multiple analyte detection The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more of a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurali... | 06/03/2008 |
| 7381571 | Device and method for analyte detection The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more of a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurali... | 06/03/2008 |
| 7378056 | Circuits for in vivo detection of biomolecule concentrations using fluorescent tags Methods are disclosed wherein labeled antibodies can be provided in vivo to tissue having antigens that specifically bind the labeled antibody. A first optical radiation is emitted into the tissue in vivo to excite the labeled antibody bound to the antigen in vivo. ... | 05/27/2008 |
| 7378283 | Reaction monitoring of chiral molecules using fourier transform infrared vibrational circular dichroism spectroscopy A method and apparatus to monitor the enantiomeric excess of chiral molecules participating in a chemical reaction. The method includes real time monitoring of the chemical reaction by obtaining a VCD spectra and an IR spectra of the chemical compounds in the reacti... | 05/27/2008 |
| 7378270 | Device for analyte measurement A biochemical analysis instrument for multiple fluid analyses includes a housing. A sensor for sensing a reaction is disposed in the housing. An aperture is formed in the housing. A test tape housing area is formed in the housing, and the sensor is disposed to selec... | 05/27/2008 |
| 7371562 | Guided mode resonant filter biosensor using a linear grating surface structure Methods and compositions are provided for detecting biomolecular interactions. The use of labels is not required and the methods can be performed in a high-throughput manner. The invention also provides optical devices useful as narrow band filters. ... | 05/13/2008 |
| 7372572 | Device for photometrically measuring the concentration of a chemical substance in a solution to be measured An apparatus for photometric measurement of the concentration of a chemical substance in a solution, wherein a cuvette is provided containing the solution The cuvette is transmissive at least in predetermined regions for electromagnetic radiation, wherein a transmit... | 05/13/2008 |
| 7371538 | Microluminometer chip and method to measure bioluminescence An integrated microluminometer includes an integrated circuit chip having at least one n-well/p-substrate junction photodetector for converting light received into a photocurrent, and a detector on the chip for processing the photocurrent. A distributed electrode co... | 05/13/2008 |
| 7371247 | Method and apparatus for penetrating tissue A tissue penetrating system includes a plurality of penetrating members each having a tip. A penetrating member driver is coupled to the plurality of penetrating members. Each tip of a penetrating member is uncovered during launch of the penetrating member by the pe... | 05/13/2008 |
| 7371347 | Device for dispensing and observing the luminescence of individual specimens in multi-specimen arrangements The invention is directed to a device for dispensing and observing the luminescence of individual specimens in multi-specimen arrangements, particularly for the examination of biological, chemical or cytobiological assays with high specimen throughput. It is the obj... | 05/13/2008 |
| 7368080 | Smear preparing apparatus A smear preparing apparatus for preparing a smear of a specimen on a glass slide by using a spreader based on a smearing condition, the apparatus includes a memory for storing smearing conditions in connection with pertinent information required for establishing the... | 05/06/2008 |
| 7368292 | Differential reflection spectroscopy system and method for detecting explosives and other target materials A system and method for identifying explosive or other target materials includes the steps of irradiating a first location and a second location spaced apart from the first location from a sample suspected of including explosives with ultraviolet, visible or infrare... | 05/06/2008 |
| 7368294 | Method for optical detection of an adjoining of a material component to a sensor material with the aid of biological, chemical or physical interaction and device for carrying out said method (variants) Method for detecting biological or chemical components in liquid or gas is based on measuring changes of the sensor layer thickness due to binding reactions. A plate or a gap with two surfaces of a solid optical material is used as the sensor layer. The surfaces are... | 05/06/2008 |
| 7368086 | Functionalized fluorescent nanocrystals, and methods for their preparation and use Functionalized fluorescent nanocrystal compositions and methods for making and using these compositions are disclosed. The compositions are fluorescent nanocrystals coated with at least one material. The coating material has chemical compounds or ligands with functi... | 05/06/2008 |
| 7368084 | Flow cytometry for high throughput screening The present invention, provides a flow cytometry apparatus for the detection of particles from a plurality of samples comprising: means for moving a plurality of samples comprising particles from a plurality of respective source wells into a fluid flow stream; means... | 05/06/2008 |
| 7368082 | Formulation of spotting solution to achieve uniform spot size and morphology and for nondestructive quality control of assay articles This invention relates to spotting solutions for the production of assay articles with uniform spot size and morphology for the detection of biopolymers, comprising N-lauroyl sarcosine in a buffered solution. Optionally the spotting solution may further comprise a f... | 05/06/2008 |
| 7368281 | Label-free evanescent-field detection of biological and chemical agents An evanescent-field sensor system and method of using the system to detect either liquid- or airborne biological pathogens, chemical agents, and other harmful or toxic species is provided. The sensor system involves 1) an evanescent-field sensor having a substrate s... | 05/06/2008 |
| 7364701 | Liquid homogenizing unit and high speed liquid chromatograph equipped with the same A liquid homogenizing unit comprising a feed flow channel (56), a discharge flow channel (57), a first intermediate flow channel (58) communicating with the feed flow channel (56), and a second intermediate flow channel (55) commun... | 04/29/2008 |
| 7364850 | DNA probe array There is used at least one probe array obtained by arraying particles having various probes, respectively, fixed thereon (probe particles) in a definite order in a holder. A plurality of capillaries or grooves packed with various kinds, respectively, of probe partic... | 04/29/2008 |
| 7364898 | Customized micro-array construction and its use for target molecule detection The present invention relates to a detection and quantification method of different sets of target molecules (1, 3), being possibly present simultaneously in a biological sample by the use of a microarray present upon a solid support surface (6) and co... | 04/29/2008 |
| 7364907 | Systems and methods for sorting samples Methods and systems for sorting compounds and compound holders into batches for subsequent processing are provided. ... | 04/29/2008 |
| 7365849 | Portable, scanning and analyzing apparatus A portable, scanning and analyzing apparatus that uses an integrated scan probe for the scanning operation is described. The integrated scanning probe is formed with a light emitting diode array light source and a photodiode detector array. After a test sample finis... | 04/29/2008 |
| 7362432 | Method and systems for dynamic range expansion Methods and systems for expanding the dynamic range of a system are provided. One method includes splitting fluorescent light emitted by a particle into multiple light paths having different intensities, detecting the fluorescent light in the multiple light paths wi... | 04/22/2008 |
| 7361509 | Dynamic metered fluid volume determination method and related apparatus A method for dynamically determining the volume of a liquid dispensed by a metering system, the metering system including a metering pump, a pump motor, a sensor, and a conduit interconnecting the pump and a metering probe. The method includes the steps of aspiratin... | 04/22/2008 |
| 7361514 | System and method for gas discharge spectroscopy A system for identifying gases, the system having a plasma generator for generating a plasma using the gas to be identified and an array of detectors for detecting light emitted from the plasma. By analysing the output of the detectors, the gas can be identified. Th... | 04/22/2008 |
| 7361313 | Methods for uniform metal impregnation into a nanoporous material The methods, systems 400 and apparatus disclosed herein concern metal 150 impregnated porous substrates 110, 210. Certain embodiments of the invention concern methods for producing metal-coated porous silicon substrates 110, 210 that exhi... | 04/22/2008 |
| 7358476 | Sensing photons from objects in channels A fluidic structure includes a channel and along the channel is a series of sensing components to obtain information about objects traveling within the channel, such as droplets or other objects carried by fluid. At least one sensing component includes a set of cell... | 04/15/2008 |
| 7358079 | Flow cell array and the utilization thereof for multianalyte determination A one- or two-dimensional arrangement of flow cells is provided, as part of an array of sample compartments, with at least one inlet and outlet for each sample compartment, formed by a base plate and a body, with an arrangement of spatial recesses corresponding to t... | 04/15/2008 |
| 7358059 | Simultaneous quantification of PIG-A associated proteins in red cells, platelets and leukocyte subsets using a single measurement A single measurement can quantify phosphatidyl-inositol glycan complementation class A (PIG-A) associated proteins in red cells, platelets and the major leukocyte subsets present in blood (lymphocytes, monocytes, neutrophils and eosinophils). The single measurement ... | 04/15/2008 |
| 7354461 | Solid fuels for fuel cells A solid fuel for use in fuel cells is presented. The solid fuel includes solid oxygenates, and mixtures for generating a gaseous fuel from the solid fuel. The solid fuel can be contained in a cartridge and reacted with a liquid reactant for generating a gaseous fuel... | 04/08/2008 |
| 7354772 | Tag free bio sensing micro strip A system and method for determining information about an assay. In one embodiment the method includes positioning a filter assembly, having an assay disposed on its surface, relative to a light source such that light from the light source is incident on the filter a... | 04/08/2008 |
| 7354727 | Method and apparatus for classifying B-lymphocytes A B-lymphocyte classifying method includes the steps of (1) preparing a measurement sample by mixing a blood sample with a lysing reagent to lyse erythrocytes and to shrink the B-lymphocytes in the blood sample, (2) letting the measurement sample flow through a flow... | 04/08/2008 |
| 7352468 | Cavity ring-down detection of surface plasmon resonance in an optical fiber resonator An apparatus and method for use with a coherent optical source to detect environmental changes. The apparatus comprises: an optical cavity, including an input coupling port, and an optical fiber section; a detector optically coupled to the optical cavity to monitor ... | 04/01/2008 |