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| Number | Title | Issue Date |
| 7153702 | Label-free methods for performing assays using a colorimetric resonant reflectance optical biosensor Methods are provided for detecting biomolecular interactions. The use of labels is not required and the methods can be performed in a high-throughput manner. The invention also relates to optical devices. ... | 12/26/2006 |
| 7153475 | Aerosol particle analyzer for measuring the amount of analyte in airborne particles Aerosol particle analyzer (APA) for measuring the amount of analyte in airborne particle is described. The APA uses an analysis liquid. In most embodiments, this analysis liquid is chosen so that when it is mixed with the particles, an optical property of the analys... | 12/26/2006 |
| 7150834 | Multiple laminar flow-based rate zonal or isopycnic separation with holographic optical trapping of blood cells and other static components The invention provides a method and apparatus for separating blood into components, may be expanded to include other types of cellular components, and can be combined with holographic optical manipulation or other forms of optical tweezing. One of the exemplary meth... | 12/19/2006 |
| 7151597 | Optical wavelength standard and optical wavelength calibration system and method The optical wavelength standard comprises a diffraction grating having a diffractive surface, an input arrangement and an output optical arrangement. The input optical arrangement is located to illuminate the diffractive surface of the diffraction grating with incid... | 12/19/2006 |
| 7149383 | Optical system with reduced back reflection An optical system is adapted to produce reduced back reflection from a receiving detector back to a light source for increased system performance. The system may optically condition light signals from the light source for projection onto the detector. The conditioni... | 12/12/2006 |
| 7148964 | Method and apparatus for detecting biomolecular interactions Method and apparatus for detecting biomolecular interactions. The use of labels is not required and the methods may be performed in a high-throughput manner. An apparatus for detecting biochemical interactions occurring on the surface of a biosensor includes a light... | 12/12/2006 |
| 7145135 | Apparatus and method for MALDI source control with external image capture A method of MALDI sample plate processing includes capturing an image of a plate positioned outside a mass spectrometer. The image is processed to identify one or more attributes of an individual sample on the plate, where the attributes are selected from a position... | 12/05/2006 |
| 7142296 | Method and apparatus for detecting biomolecular interactions Method and apparatus for detecting biomolecular interactions. The use of labels is not required and the methods may be performed in a high-throughput manner. An apparatus for detecting biochemical interactions occurring on the surface of a biosensor includes a light... | 11/28/2006 |
| 7142305 | Microchemical system There is provided a microchemical system which dispenses with the optical axis alignment and positioning of the focal point of the detecting light and that of the exciting light, and is capable of carrying out measurement with high sensitivity. The microchemical sys... | 11/28/2006 |
| 7141212 | Reading devices and assay devices for use therewith A method of “reading” the result of an assay effected by concentrating a detectable material in a comparatively small zone of a carrier in the form of a strip, sheet or layer through the thickness of which electromagnetic radiation such as visible light is trans... | 11/28/2006 |
| 7141385 | Microcantilever apparatus and methods for detection of enzymes, enzyme substrates, and enzyme effectors An apparatus and a method are provided for detecting an enzyme, or or for detecting a substrate of an enzyme or for detecting an enzyme effector such as an inhibitor, by measuring a change in deflection of a microcantilever having a substrate or an enzyme, respectiv... | 11/28/2006 |
| 7142987 | Apparatus, system, and method of archival and retrieval of samples A sample archive method and system implement a plurality of sample carriers configured to support a plurality of sample nodes in a predetermined spatial relationship, sample storage devices for selectively placing the plurality of sample carriers in an archive, and ... | 11/28/2006 |
| 7138269 | Microflow system for particle separation and analysis A micro flow system is provided for separating particles, comprising a microfabricated member having a flow channel (5) defined therein for guiding a flow of a fluid containing the particles through the flow channel, first inlet means (2) positioned at... | 11/21/2006 |
| 7135342 | Electro-optical sensing device with reference channel An electro-optical sensing device for detecting the presence and concentration of an analyte in a liquid or gaseous medium includes a pair of indicator elements positioned to receive radiation from a radiation source and transmit radiation to a pair of photosensitiv... | 11/14/2006 |
| 7135143 | Detecting compounds with liquid crystals A device for detecting a compound in a sample includes a substrate and a self-assembled monolayer. The substrate includes a support with a metallized top surface, and the self-assembled monolayer includes an alkanethiol attached to the metallized top surface of the ... | 11/14/2006 |
| 7135146 | Universal non-contact dispense peripheral apparatus and method for a primary liquid handling device A removable secondary liquid dispensing module for use with an existing, automated liquid handling system that defines a work area having a plurality of discrete work stations. Each of the work stations of the automated liquid handling system includes a lab ware sit... | 11/14/2006 |
| 7136550 | Single-fiber launch/receive system for biosensing applications An interrogation system and method are described herein which use a single-fiber launch/receive system for interrogating a biosensor (optical sensor) to detect the occurrence of a bio-chemical interaction (e.g., biological binding of ligands with analytes). In one e... | 11/14/2006 |
| 7132519 | Releasable nonvolatile mass-label molecules Releasable tag reagents for use in the detection and analysis of target molecules, particular in mass spectrometric analyses are provided. Also provided are methods of detection that employ releasable tag reagents. ... | 11/07/2006 |
| 7129096 | Sensor for use in testing biological, biochemical, chemical or environmental samples Disclosed are sensors for use in testing biological, biochemical, chemical or environmental samples, and methods of making and using the same. ... | 10/31/2006 |
| 7130027 | Reflection-photometric analytical system This invention generally relates to a reflection-photometric analytical system having a measuring head comprising a source of radiation and a radiation detector for the reflection-photometric analysis of a target surface of a test object arranged at a distance from ... | 10/31/2006 |
| 7127767 | Time-varying agitator oscillations in an automatic washer Methods and apparatuses consistent with the present invention provide for improved clothes rollover in automatic washer cycles using time-varying rotor oscillations. An automatic washer has a wash chamber with a central axis and a rotor being rotatable about the cen... | 10/31/2006 |
| 7128875 | Signal processing devices comprising biological and bio-mimetic components This invention provides modified phycobilisomes and phycobilisome complexes that are supramolecular complexes with diverse spectral properties, and which may optionally be immobilized on a manufactured solid support. The invention provides a versatile set of highly ... | 10/31/2006 |
| 7129095 | Method and system for using a weighted response The present invention is related to the sensing of analytes and in particular, to methods of determining, resolving, identifying, or quantitating such analytes once detected. This invention provides systems and methods for identifying analytes, comprising using an i... | 10/31/2006 |
| 7125592 | Detecting interactions at biomimetic interfaces with liquid crystals A method of forming a liquid crystal device, includes: contacting an aqueous solution comprising a surfactant and a receptor molecule with a top surface of a liquid crystal. The liquid crystal is in a holding compartment of a substrate, and the receptor molecule is ... | 10/24/2006 |
| 7125711 | Method and apparatus for splitting of specimens into multiple channels of a microfluidic device A microliter liquid sample, particularly a biological sample, is analyzed in a device employing centrifugal and capillary forces. The sample is moved by capillary forces into one or more metering wells which define the amount of the sample to be analyzed in subseque... | 10/24/2006 |
| 7125382 | Embedded bio-sensor system Provided is a bio-sensor system which utilizes radio frequency identification technology and which includes a remote transponder in wireless communication with an implantable passively-powered on-chip transponder. The bio-sensor system is specifically adapted to pro... | 10/24/2006 |
| 7125518 | Aerosol particle analyzer for measuring the amount of analyte in airborne particles Aerosol particle analyzer (APA) for measuring the amount of analyte in airborne particle is described. The APA uses an analysis liquid. When this analysis liquid is mixed with the particles, an optical property of the analysis liquid (CDAL) varies according to the a... | 10/24/2006 |
| 7122384 | Resonant light scattering microparticle methods Microparticle-based analytical methods, systems and applications are provided. Specifically, the use of resonant resonant light scattering as an analytical method for determining either or both a particle's identity and the presence and optionally, the concentration... | 10/17/2006 |
| 7122812 | Leak detection lamp A light source for examining sites in heating, ventilating, and air conditioning systems for leaks using a fluorescent dye is described. The light source can include a low voltage lamp or a low heat generating lamp. ... | 10/17/2006 |
| 7118916 | Method of reducing analysis time of endpoint-type reaction profiles Methods, devices and kits for facilitating medical diagnostic assays and reducing the time required for taking of such assays. The methods comprise initiating a reaction, obtaining at least three measurements, at three different time points, of a value or level of a... | 10/10/2006 |
| 7117721 | Fluid dose, flow and coagulation sensor for medical instrument In combination, an instrument for determining a characteristic of a biological fluid or a control, and a cuvette for holding a sample of the biological fluid or control, the characteristic of which is to be determined. The instrument comprises a radiation-reflective... | 10/10/2006 |
| 7118676 | Multiple laminar flow-based particle and cellular separation with laser steering The invention provides a method, apparatus and system for separating blood and other types of cellular components, and can be combined with holographic optical trapping manipulation or other forms of optical tweezing. One of the exemplary methods includes providing ... | 10/10/2006 |
| 7113285 | Multimode reader An apparatus for analyzing a plurality of samples in sample sites on a substrate, the apparatus having an array of spaced apart light sources coupled to a moveable support so that one or more of the light sources can be selectively used; a frame for supporting the s... | 09/26/2006 |
| 7110094 | Apparatus and method for carrying out analysis of samples using radiation detector output ratios A system for conducting an optical inspection of a biological, chemical, or biochemical sample supported by an optically transparent disc. The disc is mounted for rotation about its central axis while a light source and a plurality of radiation detectors are provide... | 09/19/2006 |
| 7108472 | Cartridge loader and methods A device for transporting cartridges comprises a housing for holding a plurality of cartridges in a temperature controlled environment. A transport system is also provided and has a grasping mechanism for grasping one of the cartridges. The transport system is furth... | 09/19/2006 |
| 7105354 | Analyzer An analyzer characterized by comprising a chip and a detector, wherein the chip is an organic polymer member having a fine capillary through which a fluid sample or a fluid sample and a fluid reagent flow and can perform a chemical reaction on the sample in the capi... | 09/12/2006 |
| 7105355 | Flow cytometers and detection system of lesser size Gas focusing flow cytometers are fabricatable employing simple and inexpensive manufacturing techniques. When such cytometers or conventional cytometers are combined with fiber optical light paths and laser diode and semiconductor photodetectors, light weight and ha... | 09/12/2006 |
| 7105358 | Apparatus and method for visually identifying micro-forces with a palette of cantilever array blocks An apparatus to measure micro-forces includes a cantilever palette with a set of cantilever array blocks. Each cantilever array block includes a set of cantilevers, with each cantilever including a set of cantilever fingers surrounded by a frame with frame fingers. ... | 09/12/2006 |
| 7101717 | Addressable biologic electrode array An addressable biologic electrode array includes an array of electrodes disposed on a support, the array of electrodes being selectively addressed and driven using a memory associated with each electrode of the array, the driven electrodes being driven at one of a p... | 09/05/2006 |
| 7101511 | Microplate liquid handling system A microplate liquid handling system capable of automatically performing both longitudinal collective suction/discharge and lateral collective suction/discharge on a single microplate. The microplate liquid handling system has a main body equipped with a moving devic... | 09/05/2006 |
