...During the Civil War, the Confederacy established its own Patent Office which issued 266 patents, a third of which concerned implements of war.
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| Number | Title | Issue Date |
| 7790112 | Biosensor to determine potassium concentration in human blood serum The present invention relates to the development of a biosensor to determine potassium in human blood serum using dibenzo-18-crown-6 (DB18C6) as ionophore. Human blood serum contains potassium in ppm levels i.e 137 to 200 mg/litre and sodium co exists with a 30 time... | 09/07/2010 |
| 7790113 | Visual, continuous and simultaneous measurement of solution ammonia and hydrogen ion concentration Particular aspects provide novel devices and methods for accurately measuring total ammonia (NH3 plus NH4+) in a solution (e.g., freshwater and saltwater) by spatially proximate, simultaneous and continuous quantitative measurement o... | 09/07/2010 |
| 7435384 | Diagnostic instrument with movable electrode mounting member and methods for detecting analytes An instrument (A) detects in a sample the presence of an analyte. The sample includes electrically readable particles (126) with an agent attached thereto that binds with the analyte or is an analog of the analyte. The instrument includes a port for the sampl... | 10/14/2008 |
| 7404928 | Thiol terminated monodisperse ethylene oxide oligomer capped gold nanoclusters A thiol terminated ethylene oxide oligomer and the method of substituting the oligomer onto a gold nanocluster surface using a thiol-exchange reaction to form a charge-neutral, non-ionizable, water soluble, ethylene oxide protected gold nanocluster. The thiol termin... | 07/29/2008 |
| 7381370 | Automated multi-detector analyzer An automated analyzer for analyzing patient samples. The analyzer includes a plurality of cuvettes, which allow the samples to be mixed with various reagents. The analyzer includes one or more detectors, including a detector adapted to detect luminescence of the rea... | 06/03/2008 |
| 7341692 | Detection apparatus for biological materials and methods of making and using the same Apparatus comprising a surface site layer having a distal site end, wherein the distal site end includes a substantially inorganic surface having a chemical composition selected from a group consisting of metals, semiconductors, insulators, and mixtures thereof, the... | 03/11/2008 |
| 7338639 | System and method for analyte measurement A method of measuring an analyte in a biological fluid comprises applying an excitation signal having a DC component and an AC component. The AC and DC responses are measured; a corrected DC response is determined using the AC response; and a concentration of the an... | 03/04/2008 |
| 7316700 | Self optimizing lancing device with adaptation means to temporal variations in cutaneous properties A lancing device, an embodiment of which controls the advancement and retraction of a lancet by monitoring the position of the lancet in conjunction with a lancet controller which incorporates a feedback loop for modulating the lancet driver to follow a predetermine... | 01/08/2008 |
| 7312095 | Modification of selectivity for sensing for nanostructure sensing device arrays An electronic system for selectively detecting and identifying a plurality of chemical species, which comprises an array of nanostructure sensing devices, is disclosed. Within the array, there are at least two different selectivities for sensing among the nanostruct... | 12/25/2007 |
| 7297312 | Simultaneous multianalyte electrochemical assay based on spatial resolution A simultaneous multianalyte electrochemical assay includes a cell which has a surface and the surface includes analyte binding sites i.e., antibodies or antigens on a solid phase at distinct separate locations. Separate working electrodes are located within proximit... | 11/20/2007 |
| 7226563 | Ion-detecting sensors comprising plasticizer-free copolymers Plasticizer-free ion-detecting sensors for detecting a target ion in a sample are provided. The sensor comprises a plasticizer-free copolymer comprised of polymerized units of methacrylate monomers and a polymerizable ion exchanger, wherein the methacrylated monomer... | 06/05/2007 |
| 7217393 | Apparatus and method for process monitoring An apparatus is provided for testing fluid samples includes a sensor, which can be light source, directed to a flow cell and a photo sensor for detecting a light beam reflected from the flow cell. The photo sensor monitors the fluid in the flow cell by sensing the r... | 05/15/2007 |
| 7208121 | Plasticizer-free-ion-detective sensors A plasticizer-free ion detective sensor for detecting a target ion in a sample is provided. The sensor comprises a copolymer of methacrylate monomers with pendant alkyl groups of different length, and an ionophore for detecting the target ion. The copolymer matrix o... | 04/24/2007 |
| 7201876 | Ion-detecting sensors comprising plasticizer-free copolymers Ion-detecting sensors for detecting a target ion in a sample are provided. The sensor comprises a plasticizer-free copolymer comprised of polymerized units of methacrylate monomers having pendent alkyl groups of different length and a functionalized ionophore of sai... | 04/10/2007 |
| 7195738 | Sensor and detecting method A sensor is provided for detecting a target substance in a sample by detecting a product formed in the presence of an enzyme and an enzyme substrate. The sensor comprises two or more working electrodes, a first capturing molecule immobilized on the working electrode... | 03/27/2007 |
| 7192777 | Apparatus and method for process monitoring An apparatus is provided for testing fluid samples includes a sensor, which can be light source, directed to a flow cell and a photo sensor for detecting a light beam reflected from the flow cell. The photo sensor monitors the fluid in the flow cell by sensing the r... | 03/20/2007 |
| 7189315 | Ion sensor and clinical analyzer using the same An ion sensor has a flow path through which a sample flows. An ion-exchange membrane is in contact with the sample in the sample flow path. An internal solution is provided on one side of the ion-exchange membrane. An internal electrode is provided so as to come in ... | 03/13/2007 |
| 7189573 | Apparatus and method for process monitoring An apparatus is provided for testing fluid samples includes a sensor, which can be light source, directed to a flow cell and a photo sensor for detecting a light beam reflected from the flow cell. The photo sensor monitors the fluid in the flow cell by sensing the r... | 03/13/2007 |
| 7175811 | Micro-array evanescent wave fluorescence detection device Novel nanowell microarrays are disclosed in optical contact with polymer waveguides wherein evanescent field associated with lightwaves propagated in the waveguide excite target substances in the nanowells either by a common waveguide or by individual waveguides. Fl... | 02/13/2007 |
| 7150997 | Multiplexed active biologic array A method of addressing and driving an electrode array includes the step of addressing one or more electrodes within the array using a plurality of row and column lines. In one aspect of the method, a value corresponding to a voltage is stored in a local memory assoc... | 12/19/2006 |
| 7138090 | Vapor sensor and materials therefor The present invention relates to a composition for sensor films used for detecting chemical analytes within sensors, such as polymer-absorption chemiresistors (i.e. conductometric sensors). The present invention provides sensor film compositions that have greater te... | 11/21/2006 |
| 7118916 | Method of reducing analysis time of endpoint-type reaction profiles Methods, devices and kits for facilitating medical diagnostic assays and reducing the time required for taking of such assays. The methods comprise initiating a reaction, obtaining at least three measurements, at three different time points, of a value or level of a... | 10/10/2006 |
| 7112304 | Robust chemiresistor sensor A chemiresistor sensor probe for detecting target analytes. The probe includes a body having a first control surface and a second control surface recessed within the first. A sensor film comprises numerous conductive particles disposed upon the second surface. The f... | 09/26/2006 |
| 7101717 | Addressable biologic electrode array An addressable biologic electrode array includes an array of electrodes disposed on a support, the array of electrodes being selectively addressed and driven using a memory associated with each electrode of the array, the driven electrodes being driven at one of a p... | 09/05/2006 |
| 7094353 | Method of water treatment The invention relates to a method of treatment of bodies of water such as recreational pools, spas and hot tubs with maintenance doses of water treatment chemicals to achieve consistent sanitization and aesthetically pleasing levels of properties such as turbidity. ... | 08/22/2006 |
| 7090805 | Taste recognition system and recognition method Taste recognition is performed by letting a solvent flow through a holding section which holds an object to be recognized and measuring the solvent which has flowed through the holding section by a taste sensor. If the flow rate of the solvent is set at about 1 ml/m... | 08/15/2006 |
| 7086277 | Device having a flow channel containing a layer of wicking material A device having a flow channel, wherein a layer of mesh is adhered to a surface forming a wall of a flow channel, but the layer of mesh is of such dimensions that the layer of mesh does not contact those portions of the device where electrochemical reactions occur a... | 08/08/2006 |
| 7045097 | Biologic electrode array with integrated optical detector A biologic electrode array is formed on a semiconductor substrate. A matrix of electrode sites is disposed on the semiconductor substrate. A matrix of optical detectors is disposed beneath the electrode sites in the semiconductor substrate, wherein each electrode si... | 05/16/2006 |
| 7022212 | Micro structured electrode and method for monitoring wafer electroplating baths A microstructured electrode coupled with an analytical method designed to simulate the actual conditions on the wafer and to measure critical parameters such as mass transfer of the active plating components, deposition rates of the copper in the plating bath soluti... | 04/04/2006 |
| 6977180 | Biosensor The present invention relates, in general, to biosensors and, in particular, to bioelectronic sensors comprising a macromolecule immobilized on an electrode surface so that a redox cofactor that is site-specifically attached to the surface of the macromolecule is be... | 12/20/2005 |
| 6969900 | Semiconductor diode capable of detecting hydrogen at high temperatures A semiconductor diode with hydrogen detection capability includes a semiconductor substrate, a doped semiconductor active layer formed on the substrate and made from a compound having the formula XYZ, in which X is a Group III element, Y is another Group III element... | 11/29/2005 |
| 6933153 | Metal ion specific capacity affinity sensor This invention relates to a metal ion specific capacitance sensor with exceptional sensitivity and wide operating range. It is versatile because different kinds of recognition elements can be immobilized directly in a self-assembling monolayer substantially complete... | 08/23/2005 |
| 6929728 | Sensor for measuring a gas concentration or ion concentration The invention relates to a sensor for measuring a gas concentration or ion concentration which has a substrate (11), a drain (3) formed on the substrate, a source (2) formed on the substrate, a channel area (4) of the substrate located be... | 08/16/2005 |
| 6926814 | Automatable measuring, cleaning and calibration device for pH-electrodes or electrodes for measuring redox potentials An automatable measuring, cleaning and calibrating device for pH-electrodes or electrodes for measuring redox potentials, specifically in process engineering, having an electrode armature which keeps the measuring electrode in an operating position or in a maintenan... | 08/09/2005 |
| 6881379 | Method for producing detection systems with planar arrays The invention relates to a method for producing a detection system for detecting different analytes in a sample, characterised by the following steps: providing a planar or essentially planar substrate which has sensors for chemically, optically or electrically dete... | 04/19/2005 |
| 6875621 | Magnetizable bead detector A ferromagnetic thin-film based magnetic field detection system used for detecting the presence of selected molecular species. A magnetic field sensor supported on a substrate has a binding molecule layer positioned on a side thereof capable of selectively binding t... | 04/05/2005 |
| 6867048 | Multiplexed active biologic array A method of addressing and driving an electrode array includes the step of addressing one or more electrodes within the array using a plurality of row and column lines. In one aspect of the method, a value corresponding to a voltage is stored in a local memory assoc... | 03/15/2005 |
| 6797236 | Design and signal recovery of biomolecular sensor arrays The present invention provides an apparatus and method of reducing noise associated with biomolecular measurement systems. Sensor detection system noise characteristics in the presence of other sensor detection systems are determined and advantageously used to deter... | 09/28/2004 |
| 6794197 | Microdevice and method for detecting a characteristic of a fluid A microdevice for supporting a flowing fluid is disclosed. In one embodiment, the microdevice includes a substrate and a pair of generally parallel, spaced wall members on the substrate. At least one of the wall members includes a pair of structures defining an open... | 09/21/2004 |
| 6752964 | Polymer/plasticizer based sensors This invention relates to a novel class of vapor sensors with tunable properties. More particularly, this invention relates to vapor sensors modified by the addition of a compatible small molecule of low volatility, i.e., a plasticizer. In certain aspects, the inven... | 06/22/2004 |