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| Number | Title | Issue Date |
| 8187539 | Device and method for determining material properties by means of HPLC An assembly for determining material properties and/or material concentrations of components of a sample, containing: a chromatographic separating column with a liquid mobile solvent; means for controlling the temperature inside the separating column between room te... | 05/29/2012 |
| 8173070 | Sample injector system for liquid chromatography An injection device (10) includes a carrier inlet (40), a sample inlet (46), waste outlet (44) and a chamber outlet (64) attached to separation column (66). Valves (52, 54, 56) are used to control flow such that sampl... | 05/08/2012 |
| 8007742 | IRIS digester-evaporator interface A digester-evaporator for partially digesting a sample and for evaporating the solvent after partial digestion. The digester includes at least one reaction coil; a heating element arranged along a portion of the reaction coil; at least a portion of the reaction coil... | 08/30/2011 |
| 7976779 | Integrated LC-ESI on a chip A microfluidic system with on-chip pumping which can be used for liquid chromatography and also electrospray ionization mass spectrometry and which provides improved efficiency, better integration with sensors, improved portability, reduced power consumption, and re... | 07/12/2011 |
| 7901628 | Method for fractionating various components contained in a sample solution by liquid chromatograph mass spectrometer A method for fractionating a sample solution includes the steps of setting a first mass spectrometry condition and mass range information; setting a second mass spectrometry condition and mass range information; executing a mass scan by the mass spectrum acquisition... | 03/08/2011 |
| 7524457 | Displacement chemical regeneration method and apparatus Apparatus for chromatographically separating ionic species in an aqueous electrolyte-containing eluent to form an effluent, suppressing the effluent, detecting the suppressed effluent and passing the detected effluent to a regenerant reservoir, thereby displacing th... | 04/28/2009 |
| 7442556 | Microfluidic-based electrospray source for analytical devices with a rotary fluid flow channel for sample preparation This invention provides microfluidic devices and methods for using the same. Microfluidic devices of the present invention comprises a first elastic layer, a fluid flow channel within the elastic layer; and a means for providing a fluid sample from the fluid flow ch... | 10/28/2008 |
| 7425252 | System and method An analysis system for and method of enabling determination of the velocities of migrating objects, the system comprising an equiphase space-time map generator for generating an equiphase space-time map of equiphase points from each of a plurality of data sets repre... | 09/16/2008 |
| 7425251 | System and method A system and method of characterizing, in particular sequencing, polymeric samples, the system comprising: a space-time map generator for generating a space-time map of points representative of the signal peaks of signals detected at a plurality of spaced positions ... | 09/16/2008 |
| 7416698 | Molecular topological fractionation of macromolecules A process for characterizing a sample comprising a population of linear macromolecules of interest (104) and a population of long chain branched macromolecules of interest (103), the process including four steps. The first step is to provide a flow thr... | 08/26/2008 |
| 7405083 | Method and apparatus for purifying and desalting biological samples The subject invention provides a sample processing technique for purifying a biological or chemical sample. The invention is particularly well-suited to prepare a sample for mass spectrometry. The process is to be performed in an article having at least one well, in... | 07/29/2008 |
| 7402283 | Electrolytic eluent generator and method of use An acid or base is generated in an aqueous solution by the steps of: (a) providing a source of first ions adjacent an aqueous liquid in a first acid or base generation zone, separated by a first barrier (e.g., anion exchange membra... | 07/22/2008 |
| 7393691 | SERS method and apparatus for rapid extraction and analysis of drugs in saliva The method and apparatus rapidly separate drugs and their metabolites from saliva and, in a continuous sequence of steps, rapidly detect, identify and quantify them through surface-enhanced Raman spectroscopy. ... | 07/01/2008 |
| 7393692 | SERS method for rapid pharmacokinetic analysis of drugs in saliva The method and apparatus rapidly separate drugs and their metabolites from saliva and, in a continuous sequence of steps, rapidly detect, identify and quantify them through surface-enhanced Raman spectroscopy. ... | 07/01/2008 |
| 7364701 | Liquid homogenizing unit and high speed liquid chromatograph equipped with the same A liquid homogenizing unit comprising a feed flow channel (56), a discharge flow channel (57), a first intermediate flow channel (58) communicating with the feed flow channel (56), and a second intermediate flow channel (55) commun... | 04/29/2008 |
| 7361278 | Process for producing mass transfer device and apparatus for production thereof A process for producing a mass transfer device is provided which enables packing of a packing material uniformly in a flow channel, and transfers a specified substance by flowing a fluid containing the specified substance through a flow channel on a substrate. A mas... | 04/22/2008 |
| 7361269 | Fraction collector with adjustable tray A fraction collector comprising a movable tray is provided. The movable tray may be attached to the fraction collector support system in a variety of ways and adjusted without adjusting the parts of the fraction collector support system. The moveable tray may be sta... | 04/22/2008 |
| 7357852 | Bubble-free and pressure-generating electrodes for electrophoretic and electroosmotic devices Bubble-free electrodes, electrochemical cells including bubble-free electrodes, analytical devices, and methods for preparing and using them are provided. The analytical devices each include at least one bubble-free electrode. Analytical devices that include an elec... | 04/15/2008 |
| 7357864 | Microfluidic device The object of the present invention is to provide a production process of a microfluidic device in which a porous resin layer, which is capable of optimally fixing a large amount of enzyme, antigen or other protein or catalyst on the inner surface of a minute channe... | 04/15/2008 |
| 7351245 | Apparatus and method for dislodging object from throat An apparatus for sucking out an object stuck in a person's throat, comprising hollow first and second bellows elements each having an orifice with a one-way valve and an exit valve, a tube structure comprising first and second legs having free distal ends outside th... | 04/01/2008 |
| 7347936 | Liquid chromatograph A liquid chromatograph has switching valves as a flow passage switching mechanism and an automatic sampler as an injection section. The liquid chromatograph can switch, by switching the switching valves between a concentration flow passage for concentrating the samp... | 03/25/2008 |
| 7341652 | Stationary capillary electrophoresis system A system and method for capillary electrophoresis are provided for analyzing a macromolecule prepared from a complex liquid mixture. In particular applications, methods and apparatus are provided for separating and analyzing a solution containing a denatured macromo... | 03/11/2008 |
| 7332347 | Apparatus and method for concentrating and collecting analytes from a flowing liquid stream An apparatus for concentrating and collecting one or more analytes in a flowing liquid stream of a carrier solvent composed of one or more solvent components is provided, which includes a transfer tube which forms a bore having an inlet and an outlet, the inlet bein... | 02/19/2008 |
| 7332087 | Flow sensing apparatus used to monitor/provide feedback to a split flow pumping system A method and apparatus for monitoring and controlling the nano-scale flow rate of fluid in the operating flow path of a HPLC system without relying on a nano-scale sensor in the operating flow path. A main flow sensor is disposed in the main flow path between the pu... | 02/19/2008 |
| 7329353 | LC/MS method of analyzing high molecular weight proteins The present invention is directed to a novel method of analysis of high molecular weight proteins. More specifically, it is directed to a novel reversed-phase LC/MS method of analysis of high molecular weight proteins including antibodies. ... | 02/12/2008 |
| 7329386 | Column packing material and method for producing the same The first subject of this invention is a column packing material comprising: a silica gel having a silanol group; a first chemical modification group which is bound to said silanol group; a silicon... | 02/12/2008 |
| 7329346 | Ion chromatography system using catalytic gas elimination A liquid chromatographic system is provided including catalytically combining hydrogen and oxygen gases in the chromatography eluent stream in a catalytic gas elimination chamber, to form water and thereby reduce the gas content in the eluent stream. Also, a liquid ... | 02/12/2008 |
| 7323342 | Method for improving oil desalting by forming unstable water-in-oil emulsions A method for determination for a given oil the relative stability of a water-in-oil emulsion that will be formed by that oil with water comprises measuring for the given oil the weight fraction of the oil that is most strongly adsorbed on a silica gel column success... | 01/29/2008 |
| 7318900 | Chromatography system and method A chromatography system and method for analyzing a sample of interest. The chromatography system can include a housing, a cartridge holder coupled to the housing and formed to hold a chromatography cartridge containing a stationary phase, a collection vessel stand h... | 01/15/2008 |
| 7316769 | Length-dependent recoil separation of long molecules Separation of long molecules by length is obtained by forcing such molecules to traverse a boundary between a low free-energy region and a high free-energy region. In one embodiment, the high free-energy region is a dense pillar region or other structure formed on a... | 01/08/2008 |
| 7311880 | Well-less filtration device The present invention provides a well-less filtration device that includes a pre-filter layer; a support layer; and at least one layer of solid phase extraction medium disposed between the pre-filter layer and the support layer. At least a portion of the pre-filter ... | 12/25/2007 |
| 7306720 | Membrane based volatile component-removal devices for liquid chromatography In a liquid chromatographic system, removing at least part of a volatile component from the liquid sample stream after separation by flowing it through a volatile component-removal device including a porous wall having a surface coating of a permeable polymer less t... | 12/11/2007 |
| 7297547 | Analysis of metals in acidic solutions In one embodiment, a method of neutralizing the matrix of an acidic solution including at least one metal using a weak anion exchange resin is provided. The method includes the acts of: activating the weak anion exchange resin with a weakly acidic metal complexing r... | 11/20/2007 |
| 7294309 | Small volume liquid handling apparatus and method A fluid dispensing system comprising: a fluid container; a dispensing head in fluid communication with the fluid container; a displacement mechanism which delivers fluid from the fluid container to the dispensing head such that an aliquot of liquid is delivered to a... | 11/13/2007 |
| 7290723 | Aerosol splitter for ELSD The present invention is directed to a device for splitting a propelled aerosol cloud. The device utilizes a curved spray chamber and a thermal technique to divert any desired portion of the aerosol to waste. The remainder of the aerosol is made available to an ELSD... | 11/06/2007 |
| 7291383 | Supports for solid phase extraction A support for solid phase extraction is provided for preventing the fracture of the porous body of the support and the space between the porous body and its container, and for processing various amounts of liquids to be processed while maintaining the ease of passag... | 11/06/2007 |
| 7288228 | Sample injection system An HPLC injection valve is mounted to a probe drive system close to the probe axis to minimize probe movements required for sample injections into a mobile phase column. The probe is directly connected by a short conduit to the injection valve, eliminating the need ... | 10/30/2007 |
| 7282126 | System and method for determining known DNA variants with temperature gradient electrophoresis The present invention relates to a method of determining the genotype of a sample polynucleotide having at least a first variant site. At least a portion of the sample polynucleotide is amplified to obtain first amplicons, the first amplicons including the first var... | 10/16/2007 |
| 7279094 | Chromatography methods and chromatography apparatus Ultrasound transceivers (20) are distributed up the side wall of a chromatography column (1) and enable tracking of the progress of a rising bed front (5) during packing. Comparison with a predetermined stored profile is used for feedback contro... | 10/09/2007 |
| 7276158 | Incision-based filtration/separation pipette tip This invention relates to a pipette tip designed to perform filtration or sample separation on the basis of one or more perforations, holes or incisions performed on the tip. Such perforation, holes or incisions are large enough to permit the passage of fluids or sm... | 10/02/2007 |
