"The abolishment of pain in surgery is a chimera. It is absurd to go on seeking it...knife and pain are two words in surgery that must forever be associated in the consciousness of the patient."
Dr. Alfred Velpeau, French surgeon ; 1839
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| Number | Title | Issue Date |
| 8178045 | Interchangeable preconcentrator connector assembly An interchangeable preconcentrator assembly comprises an outer housing and an inner housing defining a chamber. A biased urging member is held at least partially within the outer housing and slidably biased toward a surface of the inner housing. When the biased urgi... | 05/15/2012 |
| 8012434 | Anti-clogging device and method for in-gel digestion applications An integrated proteomics sample preparation device and method for in-gel digestion of proteins and for desalting and concentrating samples prior to further analysis such as by MALDI TOF and/or electro-spray ionization (ESI) mass spectrometry. The device in accordanc... | 09/06/2011 |
| 7749443 | Enhanced sampling device The present invention is directed to an enhanced sampling device, herein referred to as an ESD, for enhancing the collection efficiency of the SPME method by enhancing the flow of the analytes onto the sampling fiber. The ESD includes a tubular main body, used for a... | 07/06/2010 |
| 7566421 | Encapsulated sorbent tube An encapsulated sorbent tube includes a sampling sorbent tube having an open end and containing a sorbent material therein enclosed within an independent encapsulation element that has a body portion and an end portion. The body portion of the encapsulation element ... | 07/28/2009 |
| 7541003 | Latex based adsorbent chip The present invention provides an adsorbent chip, which includes three components, a substrate, an intermediate layer of linker arms and an adsorbent film, which is attached to the linker arms. The adsorbent film is made up of a plurality of adsorbent particles, eac... | 06/02/2009 |
| 7517496 | Latex based adsorbent chip The present invention provides an adsorbent chip, which includes three components, a substrate, an intermediate layer of linker arms and an adsorbent film, which is attached to the linker arms. The adsorbent film is made up of a plurality of adsorbent particles, eac... | 04/14/2009 |
| 7429356 | Extracting apparatus A loading mechanism holds at least one extracting cartridge provided with a filter member, at least one waste liquid vessel for accommodating a discharged liquid of a sample liquid and a discharged liquid of a washing liquid, which discharged liquids have been disch... | 09/30/2008 |
| 7429358 | Method and apparatus for measuring gas sorption and desorption properties of materials The invention relates to a method and an apparatus (herein referred to as a “gas sorption/desorption analyzer”) for measuring the gas sorption properties of substances (for example hydrogen sorption by metal alloys). Measurements include: Pressure Composition Te... | 09/30/2008 |
| 7427377 | Analyte concentration detection devices and methods Arrangements for the detection of the presence and/or concentration of an analyte in a sample of bodily fluid include diffuse transmission, diffuse reflection and edge or waveguide illumination arrangements. A vertical flow assay arrangement and/or technique is also... | 09/23/2008 |
| 7422724 | Biological preconcentrator A biological preconcentrator comprises a stimulus-responsive active film on a stimulus-producing microfabricated platform. The active film can comprise a thermally switchable polymer film that can be used to selectively absorb and desorb proteins from a protein mixt... | 09/09/2008 |
| 7419831 | Method and apparatus for determination of water and for normal phase liquid chromatography A method for calibrating an analysis instrument, e.g., a gas chromatograph, for water analysis that includes four steps. The first step is to continuously remove water from a liquid that contains water to produce a liquid containing a reduced amount of water such as... | 09/02/2008 |
| 7419637 | Oxides of manganese processed in continuous flow reactors Methods and systems for regenerating and pretreating oxides of manganese and precipitation of oxides of manganese from manganese salt solutions. Oxides of manganese, a slurry containing oxides of manganese or manganese salt solutions are mixed with heated aqueous ox... | 09/02/2008 |
| 7416699 | Carbon nanotube devices Nanotubes and nanotube-based devices are implemented in a variety of applications. According to an example embodiment of the present invention, a nanotube is adapted to pass current between two conductive elements. In one implementation, each conductive element incl... | 08/26/2008 |
| 7407625 | Volume-differential water assay system using hydrophilic gel Systems and methods for measuring the moisture and sediment content of a petroleum sample. In one embodiment, a sample to be tested is collected in a field bottle. The sample from the field bottle is then transferred from the field bottle, and into and through a mea... | 08/05/2008 |
| 7399449 | Microfabricated diffusion source A microfabricated diffusion source to provide for a controlled diffusion rate of a vapor comprises a porous reservoir formed in a substrate that can be filled with a liquid, a headspace cavity for evaporation of the vapor therein, a diffusion channel to provide a co... | 07/15/2008 |
| 7398671 | Micromechanical sensor element A micromechanical sensor element for recording the bonding of molecules to the micromechanical sensor element. The sensor element having a substrate and at least one electrical terminal. There is also an oscillatable element that is coupled to the electrical termina... | 07/15/2008 |
| 7393692 | SERS method for rapid pharmacokinetic analysis of drugs in saliva The method and apparatus rapidly separate drugs and their metabolites from saliva and, in a continuous sequence of steps, rapidly detect, identify and quantify them through surface-enhanced Raman spectroscopy. ... | 07/01/2008 |
| 7393691 | SERS method and apparatus for rapid extraction and analysis of drugs in saliva The method and apparatus rapidly separate drugs and their metabolites from saliva and, in a continuous sequence of steps, rapidly detect, identify and quantify them through surface-enhanced Raman spectroscopy. ... | 07/01/2008 |
| 7358099 | Process for (A) separating biological/ligands from dilute solutions and (B) conducting an immunochromatographic assay thereof employing superparamagnetic particles throughout Superparamagnetic (“SPM”) subunits of 1–30 nm average mean diameter (e.g. ferro fluid) subparticles are treated with a magnetically noninterfering substance capable of coating and covering them (e.g, BSA) and they spontaneously form agglomerates of about 100 n... | 04/15/2008 |
| 7354768 | Volume-differential assay using hydrophilic gel Systems and methods for measuring the moisture and sediment content of a petroleum sample. In one embodiment, a sample to be tested is collected in a field bottle. The sample from the field bottle is then transferred from the field bottle, and into and through a mea... | 04/08/2008 |
| 7354510 | Extracting apparatus A mechanism for introducing pressurized air into an extracting cartridge comprises an air pump, an on-off valve, and a pressure sensor for detecting an internal pressure within the extracting cartridge. The on-off valve is turned on in order to introduce the pressur... | 04/08/2008 |
| 7351743 | Therapeutic guanidines The present invention provides therapeutically useful substituted guanidines, and methods of treatment and pharmaceutical compositions that utilize or comprise one or more of such guanidines. ... | 04/01/2008 |
| 7326579 | Immunoassay method for lyzed whole blood The present invention provides an immunoassay method in which blood can be measured even without pretreatment by means of a centrifuge etc. In the present invention, antibodies or antigens in a sample are subjected to agglutination reaction with insoluble carriers o... | 02/05/2008 |
| 7323342 | Method for improving oil desalting by forming unstable water-in-oil emulsions A method for determination for a given oil the relative stability of a water-in-oil emulsion that will be formed by that oil with water comprises measuring for the given oil the weight fraction of the oil that is most strongly adsorbed on a silica gel column success... | 01/29/2008 |
| 7297547 | Analysis of metals in acidic solutions In one embodiment, a method of neutralizing the matrix of an acidic solution including at least one metal using a weak anion exchange resin is provided. The method includes the acts of: activating the weak anion exchange resin with a weakly acidic metal complexing r... | 11/20/2007 |
| 7285246 | Hand-held fluid analyzer A hand-held device detects the presence of a preselected substance in the breath. A deformable housing forms a test chamber for interacting an indicator reagent with the breath. An ampoule positioned inside the housing is ruptured by manual pressure through the wall... | 10/23/2007 |
| 7282179 | Blood testing unit and blood testing method and apparatus A blood testing unit comprises a closed vessel having a blood introducing section formed at a certain area of the closed vessel. A blood constituent separating section is located within the closed vessel to separate plasma and/or serum from the blood sample introduc... | 10/16/2007 |
| 7266990 | Flexural plate wave sensor and array A method for manufacturing a flexural plate wave sensor includes the steps of depositing an etch-stop layer over a substrate, depositing a membrane layer over the etch stop layer, depositing a piezoelectric layer over the membrane layer, forming a transducer on the ... | 09/11/2007 |
| 7264777 | Measurement of surface areas by polyvinylpyrrolidone sorption A method of quantitatively determining surface area of a sample uses polyvinylpyrrolidone (PVP) dispersed in a solution containing the sample, and determining the amount of PVP that has deposited on the sample. ... | 09/04/2007 |
| 7238505 | Immobilized DNA polymerase The present invention relates to a DNA polymerase immobilized by covalent bonding. More particularly, the present invention relates to an immobilized DNA polymerase whose activity is maximally preserved by masking the active site of the DNA polymerase and optimizing... | 07/03/2007 |
| 7235213 | System for performing blood coagulation assays and measuring blood clotting times A system for performing a blood coagulation assay, having: a reaction chamber; at least one moveable member configured to mix contents of the reaction chamber; a sensor configured to detect the presence of a blood clot formed in the reaction chamber; and a timer tha... | 06/26/2007 |
| 7232545 | Sensor for determining concentration of fluid sterilant A sensor for detecting hydrogen peroxide, comprising an element exhibiting piezoelectric properties having a metal-oxide-containing coating, the metal-oxide having a divalent or tetravalent state. ... | 06/19/2007 |
| 7229595 | Filtration column devices and methods of filtering therewith This relates to filter columns for isolating nucleic acids. The filter column is adapted for stable placement within the upper portion of standard plastic collection tubes of various sizes. The body of the filter column has a number of surfaces to accommodate placem... | 06/12/2007 |
| 7229835 | Amine detection method and materials A compound linked to a solid support (R) through a divalent linker moiety (X) and which is represented by the following formula: is disclosed. In particular, the 1-hydroxybenzotriazole-6-carboxylic acid is direct... | 06/12/2007 |
| 7227018 | Nucleic acid purification method and purification apparatus The object of the present invention is to provide a nucleic acid purification method and purification apparatus characterized by high washing efficiency where contamination does not occur and liquid does not remain in the nozzle tip. The present invention pro... | 06/05/2007 |
| 7223370 | Device for fully automated solid phase extraction Device for automatically implementing the SPE method, with a two-dimensional needle arrangement which is suitable for removing substances from different two-dimensional specimen vessel arrangements and dispensing them under pressure into a two-dimensional cartridge ... | 05/29/2007 |
| 7217393 | Apparatus and method for process monitoring An apparatus is provided for testing fluid samples includes a sensor, which can be light source, directed to a flow cell and a photo sensor for detecting a light beam reflected from the flow cell. The photo sensor monitors the fluid in the flow cell by sensing the r... | 05/15/2007 |
| 7192777 | Apparatus and method for process monitoring An apparatus is provided for testing fluid samples includes a sensor, which can be light source, directed to a flow cell and a photo sensor for detecting a light beam reflected from the flow cell. The photo sensor monitors the fluid in the flow cell by sensing the r... | 03/20/2007 |
| 7189575 | Method and device for determining the swelling behavior of polymer gels under pressure Disclosed is a method for determining the swellability and the swelling kinetics of superabsorbent material (9) such as polymer gels, for example, which comprises introducing a defined volume of the dry superabsorbent material (9) into a measuring vess... | 03/13/2007 |
| 7189573 | Apparatus and method for process monitoring An apparatus is provided for testing fluid samples includes a sensor, which can be light source, directed to a flow cell and a photo sensor for detecting a light beam reflected from the flow cell. The photo sensor monitors the fluid in the flow cell by sensing the r... | 03/13/2007 |