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| Number | Title | Issue Date |
| 8189900 | Image-based methods for measuring global nuclear patterns as epigenetic markers of cell differentiation The invention provides methods for determining the differentiation state of cells. The methods include non-invasive, non-perturbing, automatable, and quantitative methods of analysis of cell colonies, individual cells, and/or cellular structures. ... | 05/29/2012 |
| 8189899 | Methods and algorithms for cell enumeration in a low-cost cytometer The enumeration of cells in fluids by flow cytometry is widely used across many disciplines such as assessment of leukocyte subsets in different bodily fluids or of bacterial contamination in environmental samples, food products and bodily fluids. For many applicati... | 05/29/2012 |
| 8189898 | Gene expression image constructing method and gene expression image constructing system The present invention aims to provide a gene expression image constructing method and a gene expression image constructing system being able to three-dimensionally show expression patterns of a vastly larger number of genes (specifically, about 30,000 genes). In the... | 05/29/2012 |
| 8189897 | Program-controlled microscope and method for externally controlling microscopes The object in a program-controlled microscope and method for the external control of microscopes is to ensure the availability of externally generated data independent from the external control device generating the data. The microscope has an interface by which dat... | 05/29/2012 |
| 8175369 | Multi-nucleated cell classification and micronuclei scoring Methods and systems for counting nuclei for cells in a cell-containing sample are disclosed, such as carried out on a computer. The methods comprise: receiving a raw image of the cell-containing sample; transforming the raw image into a segmented image comprising on... | 05/08/2012 |
| 8175370 | Automatic cell analyzer and automatic cell analyzing method A sharp image showing a thin projecting part is acquired without using a complex dyeing method, and the analysis accuracy is improved. An automatic cell analyzer (1) comprises: an imaging unit (4) for capturing fluorescence emitted from a cell (S) and ... | 05/08/2012 |
| 8175371 | Method for imaging and differential analysis of cells Provided are methods for determining and analyzing photometric and morphogenic features of small objects, such as cells to, for example, identify different cell states. In particularly, methods are provided for identifying apoptotic cells, and for distinguishing bet... | 05/08/2012 |
| 8170321 | System and method for contour tracking in cardiac phase contrast flow MR images A method for tracking a contour in cardiac phase contrast flow magnetic resonance (MR) images includes estimating a global translation of a contour in a reference image in a time sequence of cardiac phase contrast flow MR images to a contour in a current image in th... | 05/01/2012 |
| 8160348 | Methods and system for validating sample images for quantitative immunoassays A method and system for automatically evaluating quality of a slide-mounted tissue sample includes receiving a digital image of a magnified portion of the slide-mounted tissue sample. At least one quantitative quality indicator is automatically determined for at lea... | 04/17/2012 |
| 8150136 | Image based quantitation of molecular translocation The use of an imaging system, cell compartment markers, and molecular markers in methods for correlating the movement of molecules within a cell to a particular compartment are provided, including measuring and correlating molecule movement in adherent and non-adher... | 04/03/2012 |
| 8150137 | Image processing device, image processing program, and observation system It is a proposition to reduce user's burden when performing tracking observation of a specimen. Therefore, an image processing apparatus includes a storage unit which takes in a plurality of slice images acquired from a specific area of a specimen by each of Z-stack... | 04/03/2012 |
| 8144966 | Use of endogenous fluorescence to identify invading metastatic breast tumor cells The present invention broadly provides methods and systems for detecting, identifying, and characterizing conditions, including diseases and other disorders in human or other animal subjects, by analyzing fluorescence from endogenous flavin adenine dinucleotide (FAD... | 03/27/2012 |
| 8139838 | System and method for generating MR myocardial perfusion maps without user interaction A method for automatically generating a myocardial perfusion map from a sequence of magnetic resonance (MR) images includes determining a region of interest (ROI) in a reference frame selected from a time series of myocardial perfusion MR image slices, registering e... | 03/20/2012 |
| 8135203 | Cell image processor and cell image processing method Cells showing specific characters can be separated from noise, extracted, and analyzed, through processing of a cell image. It is intended to provide a cell image processor (1) comprising: a characteristic quantity measuring section (11) which processe... | 03/13/2012 |
| 8135202 | Automated method and system for nuclear analysis of biopsy images An automated method and system for analyzing a digital image of a biopsy to determine whether the biopsy is normal or abnormal, i.e., exhibits some type of disease such as, but not limited to, cancer. In the method and system, a classifier is trained to recognize we... | 03/13/2012 |
| 8131054 | Computerized image analysis for acetic acid induced cervical intraepithelial neoplasia A method for differentiating cancerous lesions from surrounding tissue, which includes extracting an opacity parameter from acetowhite regions of pre acetic acid and post acetic acid images of a cervix. ... | 03/06/2012 |
| 8131053 | Detection of circulating tumor cells using imaging flow cytometry Photometric and morphometric features derived from multi-mode imagery of cells in flow are used as a cell analyzer to determine if a marker corresponding to a cancer cell or precancerous cell is present in the population of cells imaged. An imaging system simultaneo... | 03/06/2012 |
| 8131052 | Method of processing an image A method of processing an input image produces an output image emphasizing peak-like structures. The input image comprises input pixels and each input pixel has an intensity characteristic. The output image comprises corresponding output pixels and each output pixel... | 03/06/2012 |
| 8126250 | Image acquiring apparatus, image acquiring method, and image acquiring program A semi-automatic mode according to which an operator makes a necessary confirmation when an image pickup condition for a micro image is set with reference to a macro image is provided in controlling the acquisition of the macro image, the setting of the image pickup... | 02/28/2012 |
| 8121383 | Automated method and system for setting image analysis parameters to control image analysis operations A method and system for setting image analysis parameters to control image analysis operations. The method and system include collecting set of digital training images including a set of states for the set of digital training images. An objective function is defined... | 02/21/2012 |
| 8116550 | Method and system for locating and focusing on fiducial marks on specimen slides Methods are disclosed for locating and focusing on a fiducial mark on a specimen slide. A plurality of pixels are identified as candidate pixels. A pixel is identified as a candidate pixel based on a number of empty pixels in an area defined by boundary lines extend... | 02/14/2012 |
| 8116551 | Method and system for image analysis The present invention relates generally to a method for determining the level of expression of one or more candidate objects of interest in a biological sample. In particular, the present invention relates to a method for determining the level of expression of one o... | 02/14/2012 |
| 8111897 | Evaluation system, evaluation method, and recording medium An evaluation system includes a capture unit for capturing an image of a living tissue in which HER2 protein and cell nucleuses are dyed, a discrimination unit for identifying a cell membrane from the image of the living tissue based on dyed cell nucleuses within th... | 02/07/2012 |
| 8107710 | Automated placental measurement A method for analyzing the placenta and histology slides of placental tissue comprising: selecting a placental sample to be analyzed; obtaining a digital image of the placental sample; and performing an analysis on the digital image, wherein a mathematical algorithm... | 01/31/2012 |
| 8107711 | User interface method and system for management and control of automated image processing in high content screening or high throughput screening A user interface method and system for controlling automated image processing operations of HCS and/or HTS systems includes a graphical interface to enable user designation of an image naming convention, image sources and destinations, image processing channels, pro... | 01/31/2012 |
| 8103082 | Optimizing virtual slide image quality Systems and methods for assessing and optimizing virtual microscope slide image quality are provided. In order to determine whether a virtual slide image has any out of focus areas and is therefore a candidate for manual inspection, the various focus points used to ... | 01/24/2012 |
| 8103080 | Method for imaging and differential analysis of cells Provided are methods for determining and analyzing photometric and morphogenic features of small objects, such as cells to, for example, identify different cell states. In particularly, methods are provided for identifying apoptotic cells, and for distinguishing bet... | 01/24/2012 |
| 8103081 | Classification of samples Methods disclosed herein include: (a) determining positions of a plurality of cells based on one or more images of the cells; (b) for at least some of the plurality of cells, generating a matrix that includes two-dimensional information about positions of neighborin... | 01/24/2012 |
| 8098921 | Elastic image display method and elastic image display device According to a 2-dimensional map having longitudinal and horizontal axes indicating different elastic information, hue or luminance of each pixel is mapped correspondingly to their elastic information, and the elastic information is combined to construct one elastic... | 01/17/2012 |
| 8094914 | Microscope system and image processing method used for observation of a specimen An object of the present invention is to provide a microscope system and an image processing method which are practical and capable of imaging a specimen efficiently in a short period of time and also ensuring reduction of the data amount of a generated image. Accor... | 01/10/2012 |
| 8094916 | Biological growth plate scanner A biological growth plate scanner includes a multi-color illumination system that illuminates a biological growth plate with different illumination colors. A monochromatic image capture device captures images of the biological growth plate during illumination of the... | 01/10/2012 |
| 8094915 | “In vitro” diagnostic method for diseases affecting human or animal tissues The present invention relates to an “in vitro” diagnostic method for diseases affecting human or animal tissues, in particular for the diagnosis of diseases involving inflammation and fibrosis in human or animals, more particularly for liver diseases. More parti... | 01/10/2012 |
| 8090183 | Pattern noise correction for pseudo projections Correcting pattern noise projection images includes acquiring a set of projection images with an optical tomography system including a processor, where each of the set of projection images is acquired at a different angle of view. A threshold is applied to each proj... | 01/03/2012 |
| 8086016 | Apparatus, a method and software for analyzing a cell image A cell image analysis apparatus and method for judging, quickly and with good reproducibility, the presence or absence of a membrane translocation reaction occurring in a cell owing to application of an arbitrary stimulus to the cell using a fluorescence microscope.... | 12/27/2011 |
| 8077959 | Stain-based optimized compression of digital pathology slides A novel and useful method and system of optimized image compression of digital pathology slide images. The optimized image compression mechanism exploits the special color properties of the stained tissue represented by the digital pathology slides and provides an i... | 12/13/2011 |
| 8077960 | Methods for altering one or more parameters of a measurement system Methods for altering one or more parameters of a measurement system are provided. One method includes analyzing a sample using the system to generate values from classification channels of the system for a population of particles in the sample. The method also inclu... | 12/13/2011 |
| 8077958 | Computer-aided pathological diagnosis system The present invention is a computer-aided pathological diagnosis method for the classification of cancer cells in a tissue specimen based on a digital cellular image of the tissue specimen. The method of the present invention includes the steps of, extracting the hi... | 12/13/2011 |
| 8073233 | Image processor, microscope system, and area specifying program An image processor that can suitably specify a predetermined area of a grayscale image is provided. An extreme value coordinate acquiring unit performs scanning on at least one of a plurality of pixels including a target pixel from the target pixel in accordance wit... | 12/06/2011 |
| 8064678 | Automated detection of cell colonies and coverslip detection using hough transforms The present invention provides methods and systems for automatic detection of the location of cell colonies on a specimen slide, in particular under the coverslip of a specimen slide. Slide scanning can be performed using an automated microscope with motorized axes.... | 11/22/2011 |
| 8064679 | Targeted edge detection method and apparatus for cytological image processing applications Edges in cytological image data are identified by obtaining a digital image of a specimen and computing a gradient image from the obtained digital image. A scaling function is applied to the grayscale image to identify regions of interest (e.g., edges of cell nuclei... | 11/22/2011 |
