...that Charles Goodyear performed some of his experiments on rubber while in debtor's prison? He was there so often he referred to it as his "hotel". Chronically in debt because of poor business sense and ill health, Goodyear depended on the generosity of friends and family. Even after he unlocked the secret to vulcanizing rubber, he was unable to improve his financial situation. When he died, his estate was $200,000 in debt.
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| Number | Title | Issue Date |
| 7593097 | Method for determining a test strip calibration code for use in a meter A method for determining a test strip calibration code for use in a meter includes inserting a test strip into the meter. The inserted test strip having a substrate with a working surface for receiving the body fluid sample and a reverse surface that is in oppositio... | 09/22/2009 |
| 7589828 | System for analyte determination that includes a permutative grey scale calibration pattern A system for measuring an analyte in a body fluid sample includes a meter, with a grey scale photodetector module, and a memory module. The system also includes a test strip. The test strip has a substrate with a working surface for receiving the body fluid sample a... | 09/15/2009 |
| 7586590 | Calibration code strip with permutative grey scale calibration pattern A calibration strip for use with a package of test strips includes a substrate with and a permutative grey scale calibration pattern disposed on a surface of the substrate with the permutative grey scale calibration pattern including more than one grey scale region.... | 09/08/2009 |
| 7474390 | Test strip with permutative grey scale calibration pattern A test strip for the determination of an analyte, such as glucose, in a body fluid sample (for example, a whole blood sample) includes a substrate with a working surface for receiving the body fluid sample and a reverse surface that is in opposition to the working s... | 01/06/2009 |
| 7474391 | Method for determining a test strip calibration code using a calibration strip A method for determining a test strip calibration code for use in a meter includes inserting a calibration strip into the meter, with the calibration strip having a substrate and a permutative grey scale calibration pattern disposed on the substrate. In addition, th... | 01/06/2009 |
| 7444005 | Apparatus and method for using optical mouse engine to determine speed, direction, position of scanned device and to obtain quantitative or qualitative data from same A test strip reader is provided with an optical mouse integrated circuit sensor that reads the test line, reference line and control line of a lateral flow assay strip by light absorption and determines the position of the test strip beneath the image on the integra... | 10/28/2008 |
| 7432105 | Self-calibration system for a magnetic binding assay A self-calibrated, magnetic binding assay (e.g., sandwich, competitive, etc.) for detecting the presence or quantity of an analyte residing in a test sample is provided. The magnetic binding assay includes detection probes capable of generating a detection signal (e... | 10/07/2008 |
| 7326579 | Immunoassay method for lyzed whole blood The present invention provides an immunoassay method in which blood can be measured even without pretreatment by means of a centrifuge etc. In the present invention, antibodies or antigens in a sample are subjected to agglutination reaction with insoluble carriers o... | 02/05/2008 |
| 7230696 | Calibration of instruments for measuring the permeability of a material A system that calibrates instruments for measuring the light or air permeability of a material, and includes a calibration target which can be used for calibration of either light-based or air-based instruments. The calibration target simulates the material whose pe... | 06/12/2007 |
| 7076115 | Analysis of chemical data from images Computer programs and computer-implemented methods implement techniques for evaluating experimental data from a library of materials. The techniques receive a plurality of images of a library of materials that includes an array of members associated with locations i... | 07/11/2006 |
| 6855562 | Immunoassay method for lyzed whole blood The present invention provides an immunoassay method in which blood can be measured even without pretreatment by means of a centrifuge etc. In the present invention, antibodies or antigens in a sample are subjected to agglutination reaction with insoluble carriers o... | 02/15/2005 |
| 6711516 | Method for calibrating spectrophotometric apparatus Described is a method for calibrating a spectrophotometric apparatus. This method involves obtaining a first set of absorbance measurements of a set of calibrators on a First Apparatus that is in control at wavelengths from a first wavelength calibration table. A se... | 03/23/2004 |
| 6470279 | Method for calibrating spectrophotometric apparatus with synthetic fluids to measure plasma and serum analytes Described is a method for calibrating a spectrophotometric apparatus which is used to measure analytes in plasma and/or serum samples based on the calibration of a First Apparatus, and for recalibrating such apparatus, including recalibration of the First... | 10/22/2002 |
| 6441890 | Method and apparatus for timing intermittent illumination of a sample tube positioned on a centrifuge platen and for calibrating a sample tube-imaging system Centrifuged material layer volumes are measured and quantified during centrifugation of the material layers contained in a sample tube in a centrifuge assembly, which sample tube is disposed on a centrifuge platen. The material layers in the sample tube a... | 08/27/2002 |
| 6262799 | Method and apparatus for rapid measurement of cell layers Centrifuged material layer volumes are measured and quantified during centrifugation of the material layers. The material layers are differentially highlighted by means of one or more supravital fluorescent dyes or stains which are admixed with the sample... | 07/17/2001 |
| 6188470 | Bioenergetic data collection apparatus A Bioenergetic Data Collection Apparatus utilizing a modified oximeter (1) to collect signals characteristic of blood flow in terminal tissue, such as a finger tip (12). A processing means (7) in signal connection with the modified oximeter (1) receives a... | 02/13/2001 |
| 6151107 | Method of non-invasive determination of oxygen saturation in tissue in which blood is circulating In a method for the non-invasive determination of the oxygen saturation in tissue supplied with blood, the tissue is irradiated with red and infrared light and the DC and AC components of the emerging light are measured. During a first time interval, a ca... | 11/21/2000 |
| 6005658 | Intermittent measuring of arterial oxygen saturation of hemoglobin Described is a method and a system for detecting the arterial oxygen saturation of hemoglobin (also called blood oxygenation, SpO2 or SaO2 measuring), comprising a measuring device for performing a blood oxygenation measurement and a controller unit. The ... | 12/21/1999 |
| 5995208 | Intravascular oximetry catheter Apparatus and a method for monitoring a percentage of the oxygen saturation in the hemoglobin of blood flowing through a blood vessel. An optical sensor that detects the percentage oxygen saturation in blood is disposed proximate a proximal end of the cat... | 11/30/1999 |
| 5872860 | Calibration cassette for use in calibrating an automated agglutination reaction analyzing system A method, and a calibration device, for calibrating a system for analyzing aqueous solutions and that includes a pixel array and a variable focus line for focusing onto the pixel array illuminated images of the aqueous solutions. The method includes the s... | 02/16/1999 |
| 5837547 | Flow cytometer calibration method A method for calibrating a flow cytometer or fluorescence microscope and for quantitating binding proteins, such as antibodies. Populations of microbeads are provided which are in equilibrium with a saturating amount of fluorescently-labeled protein. The ... | 11/17/1998 |
| 5799101 | Method and apparatus for highly efficient computer aided screening A computer aided biological specimen screener is responsive to a priori information about biological specimens. An automated slide classifier scans a slide specimen and generates a set of scores. The classification which results from this set of scores de... | 08/25/1998 |
| 5715326 | Cytological system illumination integrity checking apparatus and method A method for checking cytological system illumination including the steps of checking global illumination variation, static field uniformity, dynamic field uniformity, specimen thickness variation, strobe repeatability, calibration plate cleanliness, and ... | 02/03/1998 |
| 5589393 | Method for preparing a glycated hemoglobin solution The invention is a rapid, continuous test for glycated hemoglobin using a non-equilibrium affinity binding method. Agarose beads derivatized with 3-aminophenylboronic acid specifically bind glycated hemoglobin. This solid phase is incorporated into a samp... | 12/31/1996 |
| 5316727 | Measuring apparatus A measuring apparatus of the present invention measures the constituent concentration of a specimen after loading into the apparatus a test piece having a test material which develops coloring as a result of a reaction with the constituents of a specimen.... | 05/31/1994 |
| 5278627 | Apparatus for calibrating pulse oximeter An apparatus for calibrating a pulse oximeter which can improve the repetitivity of measured values for calibration tests and which can calibrate the pulse oximeter with a high reliability. A tissue model having a light-absorbing characteristic approximat... | 01/11/1994 |
| 5149503 | Apparatus for measuring hemoglobin concentration and oxygen saturation thereof A light beam having a first wavelength (λ1) is applied to the blood from a first light radiation section, while a light beam having a second wavelength (λ2) is applied from second and third light radiation sections different in pos... | 09/22/1992 |
| 5089416 | Method of use of non-fluorescent particles to determine fluorescence threshold of a flow cytometer relative to the autofluorescence of samples A qualitative and quantitative method of determining the fluorescence threshold of an instrument and of determining whether the instrument is sensitive enough to measure the autofluorescence of a sample. The method utilizes non-fluorescent particles such ... | 02/18/1992 |
| 5084394 | Method for corrective calibration of a flow cytometry using a mixture of fluorescent microbeads and cells The use of a combination of calibrated microbead populations with one or more calibrated biological cell populations to correct calibration of a flow cytometer for size and fluorescence intensity determinations of biological cell samples. The use of calib... | 01/28/1992 |
| 4981361 | Color comparison device having a color sample-bonding wheel which permits easy removal of a color sample sticker A color comparison device uses a rotatable color sample-bonding wheel to hold a sticker containing a plurality of color shades for matching with a color of a test portion of a test stick as the wheel rotates. At least one recess is formed in a part of the... | 01/01/1991 |
| 4968137 | Devices and procedures for in vitro testing of pulse oximetry monitors A device and method for calibration of pulse oximeters is disclosed. A standard specimen that has optical characteristics of hemoglobin of a known oxygen saturation is placed in the light path of a pulse oximeter probe. The image of a pulse is created by ... | 11/06/1990 |
| 4877580 | Assay kit including an analyte test strip and a color comparator An assay kit comprising an analyte test strip and a color comparator including a plurality of different color fields arranged in an ordered, preferably linear, succession. There is an aperture through each color field so positioned that the reaction zone ... | 10/31/1989 |
| 4871258 | Color test meter A colorimeter comprises a case, a liquid crystal display (LCD) mounted on the case, a color chart provided on the case to permit holding of a specimen to be compared in close proximity to the color chart, and switches for indicating which color on the col... | 10/03/1989 |
| 4834532 | Devices and procedures for in vitro calibration of pulse oximetry monitors A device and method for calibration of pulse oximeters is disclosed. A standard specimen that has optical charactertistics of hemoglobin of a known oxygen saturation is placed in the light path of a pulse oximeter probe. The image of a pulse is also creat... | 05/30/1989 |
| 4797256 | Registration device for blood test strips A ring-shaped registration device for receiving and holding an activated test strip having a reagent area adapted to receive a blood sample. The registration device is slidably received on the outer peripheral surface of a cylindrical vial on which markin... | 01/10/1989 |
| 4796636 | Noninvasive reflectance oximeter A noninvasive optical oximeter for measuring oxygen saturation of arterial blood. A sample of blood is illuminated with light at two different wavelengths. Light reflected by the blood is sensed by a photodetector and an output signal is created in respon... | 01/10/1989 |
| 4744656 | Disposable calibration boot for optical-type cardiovascular catheter The catheter tip fits into a cavity in the boot and is held gently (in the longitudinal direction) by a detent formed within the cavity. A calibration substance faces the tip in a mechanically and optically standardized calibration relationship, to reflec... | 05/17/1988 |
| 4650327 | Optical catheter calibrating assembly A calibrating device for an optical catheter is provided in order to calibrate the catheter for use in a catheter oximeter system. The calibrating device includes a tube having a reference block therein which is spring-loaded into compliant engagement wit... | 03/17/1987 |
| 4340281 | Method and apparatus for estimating the endothelial cell density Endothelial cell density is determined by comparing the specular image of the endothelium at a predetermined magnification with a set of grids each having a plurality of apertures formed in a hexagonal, honeycomb pattern. The apertures in each of the grid... | 07/20/1982 |
| 4322164 | Sterilizable, disposable optical scattering reference medium and container assembly An optical scattering reference medium is formed of a plurality of scattering particles substantially uniformly dispersed in a substantially compliant, non-compressable transparent solid medium which is selectively positionable against the distal end of a... | 03/30/1982 |