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"Flight by machines heavier than air is unpractical and insignificant, if not utterly impossible."
Simon Newcomb, astronomer ; Said in 1902, less than two years before the first flight at Kitty Hawk
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| Number | Title | Issue Date |
| 8089628 | Pulsed-multiline excitation for color-blind fluorescence detection The present invention provides a technology called Pulse-Multiline Excitation or PME. This technology provides a novel approach to fluorescence detection with application for high-throughput identification of informative SNPs, which could lead to more accurate diagn... | 01/03/2012 |
| 8081310 | Multimarking fibre-type fluorescence microscopic imaging method and system The invention relates to a method for producing a fluorescent fiber image of a sample, wherein a sample is scanned with the aid of an excitation signal; the fluorescent signal emanating from the sample is detected, wherein the excitation signal and fluorescent signa... | 12/20/2011 |
| 8072603 | Fluorescence-activated cell detector An apparatus for detecting particles of interest that are dispersed in a fluid mix, which typically includes other particles. The apparatus typically is associated with an interrogation platform arranged to operate in harmony with an opaque member having an orifice ... | 12/06/2011 |
| 8049893 | Methods of identifying analytes and using encoded particles A method of identifying analytes that react with probes on encoded particles. The method includes providing a support substrate that has a plurality of the particles randomly distributed on the support substrate. The particles have elongated bodies with codes that e... | 11/01/2011 |
| 8040515 | Fluorescence detection apparatus and method, and prism used therein In order to provide a fluorescence detection apparatus having a high sensitivity, a high processing capacity and a competitive edge in cost, the fluorescence detection apparatus according to this invention irradiate the sample with light so that the aspect ratio of ... | 10/18/2011 |
| 7961323 | Microarray imaging system and associated methodology An apparatus and method are provided for creating an image of a microarray. The apparatus includes at least one light source configured to direct light toward the microarray. The apparatus includes an excitation filter configured to filter the light into a first fre... | 06/14/2011 |
| 7903248 | Luminescence measuring apparatus To increase the direct light received by the detector and decrease reflections from the detection component support structures, the luminescent substance is placed as close to the detector as possible. More specifically, the apparatus is configured so as to slide ou... | 03/08/2011 |
| 7898665 | Light emitting diode illumination system In various embodiments of the invention, a unique construction for Light Emitting Diodes (LEDs) with at least one luminescent rod and extracting optical elements is used to generate a variety of high brightness light sources with different emission spectra. In an em... | 03/01/2011 |
| 7894067 | Method and apparatus for the high spatial resolution imaging of a structure marked with a substance For the high spatial resolution imaging of a structure in a sample (2) the structure is marked with a substance which can be changed over by means of a first electromagnetic signal (5) from a first state having a larger absorption cross section for a s... | 02/22/2011 |
| 7894066 | Method and apparatus for carrying out a burning test on a test piece The image data capture of a test piece is performed with at least one first camera. A reference point of the test piece is determined by processing the image data recorded with the at least one first camera. A burner is positioned at a prescribed first distance from... | 02/22/2011 |
| 7889341 | Multiphoton-excitation laser scanning microscope A multiphoton-excitation laser scanning microscope capable of efficiently collecting fluorescence emitted from a specimen to acquire a brighter multiphoton-excitation fluorescence image is provided. This multiphoton-excitation laser scanning microscope includes a mu... | 02/15/2011 |
| RE42090 | Method of sorting waste paper Apparatus and methods are provided for sensing the presence of bright white paper on a conveyor of a paper sorting system. The conveyor is constantly illuminated with ultraviolet light. When bright white paper is present in the inspection zone of the conveyor, it wi... | 02/01/2011 |
| 7872752 | Detector system for unidentified substances Disclosed herein is a detection system for identifying an unidentified substance in a sample, comprising light emitting sources, where at least one of the light emitting sources emits light in the infrared region; a circuit board; a trigger, that activates a pulse o... | 01/18/2011 |
| 7869042 | Fluorometers In apparatus for the production and detection of fluorescence at a sample surface, the height of the apparatus above the sample surface is reduced, and loss of the emitted fluorescence due to reflection loss and light scattering is minimized. The apparatus comprises... | 01/11/2011 |
| 7859670 | System and method for detecting fluorescence in microfluidic chip A system and a method for detecting fluorescence in a microfluidic chip having a microchamber and measuring the amount of the fluorescence are disclosed. In the system and method, an optical device detects fluorescence generated by a fluorescent material. The positi... | 12/28/2010 |
| 7852479 | Apparatus and method for measuring the fluorescence of large multi-cellular organisms Apparatus and methods for measuring the fluorescence of large multi-cellular organisms in a sample of liquid includes a pumping mechanism, a fluorescence measuring device, a method of analyzing the measurements, and optionally, a sorting mechanism. The pumping mecha... | 12/14/2010 |
| 7847941 | Fiber optical assembly for fluorescence spectrometry A system for analyzing a sample for the presence of an analyte in a sample. The system includes a sample holder for containing the sample; an excitation source, such as a laser, and at least one linear array radially disposed about the sample holder. Radiation from ... | 12/07/2010 |
| 7843566 | Device for detection and measurement of a target compound such as a food toxin Apparatus comprising a holder for a sample which comprises a packing or coating capable of immobilising or isolating a target compound in a layer or band, an excitation unit that emits radiation that excites fluorescence in a target compound or derivatised target co... | 11/30/2010 |
| 7843568 | Enhanced instrumentation and method for optical measurement of samples The present invention relates generally to the field of biochemical laboratory instrumentation for different applications of measuring properties of samples on e.g. microtitration plates and corresponding sample supports. The object of the invention is achieved by p... | 11/30/2010 |
| 7843567 | Methods of identifying an analyte and nucleic acid analysis A method of identifying an analyte. The method includes providing a plurality of microparticles. The microparticles have optically detectable codes extending along bodies of the corresponding microparticle. The microparticles have the chemical probes attached theret... | 11/30/2010 |
| 7839507 | Minimizing effects of dye crosstalk Methods and systems for processing signals to minimize the effects of dye crosstalk. Deconvolution of multiplexed dye signals can include corrections for residual error determined from experimental measurements. Residual error corrections can account for reaction or... | 11/23/2010 |
| 7830516 | Automated seed sampler and methods of sampling, testing and bulking seeds An automated seed sampler includes a sampling station, a sampler for removing material from a seed in the sampling station; a seed conveyer for conveying the seed from the sampling station to a compartment in a seed tray, and a conveyor for conveying the material re... | 11/09/2010 |
| 7830515 | Method and apparatus for detection of bioaerosols A method and apparatus for evaluating a bioaerosol sample is provided which includes detecting frequency and/or time resolution factors that allow discriminate between a plurality of signals emitted by the bioaerosol to selectively detect biological materials contai... | 11/09/2010 |
| 7821640 | Method and device for reconstructing a three-dimensional fluorescence optical tomography image by double measurement To examine a plate-shaped object comprising fluorophores and having a first face and an opposite second face, the method comprises a first sequential illumination step of the first face of the object with a fluorophore excitation light and a first sequential acquisi... | 10/26/2010 |
| 7812952 | Device for reading plates bearing biological reaction support microdepositions A method for reading slides bearing fluorescent deposits, such as used in serology or molecular biology analysis, includes: incubating a slide with a sample of serum from a patient, or a dilution thereof, and revealing antibodies in the sample bound to the deposits ... | 10/12/2010 |
| 7777885 | Diagnostic imaging device for the analysis of circulating rare cells The present invention provides a system for imaging circulating tumor cells from blood after enrichment. The system is designed to provide optimum use in a clinical laboratory setting with minimum laboratory bench top space. Operator intervention is minimized compar... | 08/17/2010 |
| 7773223 | Image scanning apparatus and image scanning method An image scanning apparatus has an organic CMOS image sensor mounted in a base, and a photoreceptive surface of the image sensor is exposed on a top side of the base. A subject is placed directly on the photoreceptive surface, and the subject and the photoreceptive ... | 08/10/2010 |
| 7764378 | Methods for improving the performance of a detector A system and method for allowing adjustments of various parameters associated with the operation of charge-coupled devices adapted for use in biological analysis devices. Gate voltage signal applied to the CCDs can be adjusted to advantageously affect the manner in ... | 07/27/2010 |
| 7715008 | System and method of optically monitoring contamination of a machine component A system and method for optically monitoring contamination of machinery includes an optical illumination source, a photodetector and an analysis module. The system and method can monitor a fuser roll, a fuser belt, or other printer module component. The optical illu... | 05/11/2010 |
| 7705987 | Fluorescence correlation microscopy with real-time alignment readout This invention relates to a confocal fluorescence correlation microscope with real-time alignment read out. With this instrument it is possible to do confocal imaging together with the particle size determination at a chosen location in the specimen. In particular, ... | 04/27/2010 |
| 7701578 | Planar micro-discharge gas detector A micro-sized gas detecting device with two electrodes separated by a gap of width ranging from 1 to 500 microns, where the detection is based on emission spectroscopy of gases in an electric discharge across the gap (discharge region) as the gas flows through the r... | 04/20/2010 |
| 7701579 | Fluorescence sensor A fluorescence sensor comprises a sensor section for collecting a fluorescent substance, which acts to represent presence of a substance to be detected in a sample, and an exciting light source, which produces exciting light for exciting the fluorescent substance to... | 04/20/2010 |
| 7684042 | Device having an optical part for analyzing micro particles Disclosed is a micro particle analyzing device illuminating light to fluid including micro particles, reading the lights emitted from the micro particles at a signal processing reading section and thus analyzing the micro particles. The device comprises a light sour... | 03/23/2010 |
| 7679745 | Time-resolved fluorescence spectrometer for multiple-species analysis A time-resolved, fluorescence spectrometer makes use of a RadiaLight® optical switch and no dispersive optical elements (DOE) like gratings. The structure is unique in its compactness and simplicity of operation. In one embodiment, the spectrometer makes use of onl... | 03/16/2010 |
| 7659983 | Hybrid random bead/chip based microarray A method and apparatus for performing an assay process, featuring providing microbeads in a solution, each microbead having a particle substrate with a grating with a superposition of different predetermined regular periodic variations of the index of refraction dis... | 02/09/2010 |
| 7633620 | Laser-induced fluorescence detection device and method Disclosed is a lateral flow quantitative assay method which can measure one or more analyte species at the same time, with high sensitivity. Also, the present invention relates to a strip which can measure one or more analyte species at the same time, with high sens... | 12/15/2009 |
| 7626703 | Optical microscopy with phototransformable optical labels Spatially-structured activation radiation having relatively high- and low-intensity regions is provided to a sample that includes phototransformable optical labels (“PTOLs”). A subset of the PTOLs located predominately at relatively high intensity regions of the... | 12/01/2009 |
| 7626704 | Methods and systems for simultaneous real-time monitoring of optical signals from multiple sources Methods and systems for real-time monitoring of optical signals from arrays of signal sources, and particularly optical signal sources that have spectrally different signal components. Systems include signal source arrays in optical communication with optical trains... | 12/01/2009 |
| 7623242 | Device and method for monitoring multiple chemical samples with a fluorescent tube A monitoring device is described for multiple chemical reactions in multiple test containers. Each container contains chemical reagents and at least one fluorescence dye indicator capable of changing its fluorescent characteristics due to the chemical reaction. A si... | 11/24/2009 |
| 7612883 | Dynamic plasmonics-enabled signal enhancement, a device comprising the same, and a method using the same Disclosed herein is a plasmonics platform comprising a substrate; a plurality of periodically spaced nanoholes and/or nanoparticles disposed upon the substrate; wherein the average first order of periodicity between the nanoholes and/or the nanoparticles is about 5 ... | 11/03/2009 |
