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| Number | Title | Issue Date |
| 8189177 | Sample preparation apparatus and sample preparation method, and cell analyzer and cell analysis method A sample preparation apparatus comprising: a detector for detecting a predetermined cell included in a biological sample; a sample preparation section for preparing a measurement sample from the biological sample and a predetermined reagent; and a controller configu... | 05/29/2012 |
| 7990524 | Stochastic scanning apparatus using multiphoton multifocal source A rapid-sampling stochastic scanning multiphoton multifocal microscopy (SS-MMM) fluorescence imaging technique enables multiparticle tracking at rates upwards of 1,000 times greater than conventional single point raster scanning. Stochastic scanning of a diffractive... | 08/02/2011 |
| 7986399 | Portable sample preparation and analysis system for micron and sub-micron particle characterization using light scattering and absorption spectroscopy There is provided a method and device for remote sampling, preparation and optical interrogation of a sample using light scattering and light absorption methods. The portable device is a filtration-based device that removes interfering background particle material f... | 07/26/2011 |
| 7956989 | Surface plasmon assisted microscope The present invention includes a microscope and a method for using the microscope for single molecule with reduced photobleaching of a fluorophore (20) that includes a light translucent material (16); a metal layer (18) disposed on the light tra... | 06/07/2011 |
| 7956990 | Biochip, biochip reader and biochip reading method A biochip for implementing analysis on the basis of the distribution of a quantity of light of fluorescent light generated at sites disposed thereon, the biochip having, markers formed thereon and defined previously in a positional relationship relative to the sites... | 06/07/2011 |
| 7907259 | Laser microdissection method, control system for a laser microdissection device and carrier device A microdissection method for separating and taking a target zone of a biological preparation, disposed on a carrier device with a laser light-absorbent incisable layer and a carrier means, comprises cutting the preparation and the incisable layer along an edge segme... | 03/15/2011 |
| 7808619 | System for assembling a fluid analysis apparatus A fluid analysis apparatus includes a cell body having a chamber disposed therein for containing fluid during analysis thereof. The chamber is specifically configured to operably and statically secure a radiant energy guiding member solely through surface-to-surface... | 10/05/2010 |
| 7791716 | System and method for liquid delivery evaluation using solutions with multiple light absorbance spectral features A system and related method for improved liquid delivery evaluation using a solution containing one or more dyes such that the solution exhibits multiple distinct detectable light absorbance spectral features for calibrating or testing over extended volume or diluti... | 09/07/2010 |
| 7652756 | Method and apparatus for centering an ophthalmic lens An ophthalmic lens , e.g. a contact lens, is centered in a concave trough (10) of an inspection cell (1) which is filled with liquid (W). The inspection cell (10) has a channel (11) which is in communication with the concave trough (10... | 01/26/2010 |
| 7499152 | Method for measuring a tool of a machine tool The present invention relates to a method for measuring a tool 1 of a machine tool, the tool 1 being measured by means of a laser measurement device 2, 3, 4, characterized in that the tool 1 is sprayed with an oil- or grease-dissolving agent prior to laser measureme... | 03/03/2009 |
| 7456938 | Laser microdissection on inverted polymer films Systems and methods for automated laser microdissection are disclosed. A sample of biological material is located between a polymer membrane and a substrate. Targeted biological material is manually or automatically selected and a transfer film is placed in juxtapos... | 11/25/2008 |
| 7443489 | Surface enhanced spectroscopy-active composite nanoparticles Metal nanoparticles associated with a spectroscopy-active (e.g., Raman-active) analyte and surrounded by an encapsulant are useful as sensitive optical tags detectable by surface-enhanced spectroscopy (e.g., surface-enhanced Raman spectroscopy). ... | 10/28/2008 |
| 7415144 | Cell observation device and cell observation method The cell observation device and method aims to easily study the correlation between initial states of cells and their reactions without using a synchronous culture method. For this purpose, the cell observation device includes an image acquisition unit acquiring an ... | 08/19/2008 |
| 7407531 | Particle surface treatment for promoting condensation A system is disclosed for condensation particle counting in conjunction with modifying an aerosol to enhance the formation and growth of droplets of a selected working fluid, preferably water. Before saturation with the working fluid, the aerosol is exposed to an ae... | 08/05/2008 |
| 7371517 | High purity X-chromosome bearing and Y-chromosome bearing populations of spermatozoa Isolated non-naturally occurring populations of spermatozoa (15) having high purity and technologies to differentiate spermatozoa (28) based on characteristics such as mass, volume, orientation, or emitted light including methods of analysis and appara... | 05/13/2008 |
| 7372985 | Systems and methods for volumetric tissue scanning microscopy In accordance with preferred embodiments of the present invention, a method for imaging tissue, for example, includes the steps of mounting the tissue on a computer controlled stage of a microscope, determining volumetric imaging parameters, directing at least two p... | 05/13/2008 |
| 7369947 | Quantification of adsorbed molecular contaminant using thin film measurement A test method for measuring adsorbed molecular contamination uses a test structure that includes a substrate comprising a plurality of separated test sites having a plurality separate thicknesses having a base design thickness and a designed thickness interrelations... | 05/06/2008 |
| 7362431 | Non-invasive identification of fluorescent dyes in historic textiles by matrix transfer-surface enhanced Raman scattering A new process is presented to non-invasively identify organic dyes in historic textiles and other works of art. A small gel bead loaded with a SERS substrate is used to gently extract microscopic amounts of dyes from works of art, without the need to remove a sample... | 04/22/2008 |
| 7354733 | Method for sorting and separating living cells We disclose methods of sorting or separating mixtures of living cells (e.g., eukaryotic, prokaryotic, mammalian, pathogenic, bacterial, viral, etc.). We perform our methods by activating cell-selective photophoric labels, which photosensitize and chemically reduce a... | 04/08/2008 |
| 7330308 | Alignment method of micro-alignment members and device thereof An alignment method of micro-alignment members includes a first step for moving a reticle, which is movably disposed between a first position and a second position, to face a first microscope in the first position, and for aligning a center of the reticle with an op... | 02/12/2008 |
| 7304302 | Systems configured to reduce distortion of a resist during a metrology process and systems and methods for reducing alteration of a specimen during analysis Various systems configured to reduce distortion of a resist during a metrology process are provided. The systems include an electron beam metrology tool configured to measure one or more characteristics of one or more resist features formed on a specimen. The electr... | 12/04/2007 |
| 7283228 | Process and apparatus for segregation and testing by spectral analysis of solid deposits derived from liquid mixtures Micro-droplets of liquid confining organic molecules of interest are dried on selected planar solvo-phobic substrates under conditions facilitating segregated precipitation of the larger, less soluable analytes toward edge portions of the deposit. Micro-spectrometer... | 10/16/2007 |
| 7276377 | Method and apparatus for determining anticoagulant therapy factors Methods and apparatus are disclosed for determining a new anticoagulant therapy factor (nATF) for monitoring oral anticoagulant therapy to help prevent excessive bleeding or deleterious blood clots that might otherwise occur before, during or after surgery. In one e... | 10/02/2007 |
| 7271387 | Laser desorption and thermal emission spectroscopy for chemical analysis of cryogenic surfaces A method for remote analysis of materials embedded in a frozen surface, such as in the icy surface of a planetary body. A laser on board a spacecraft irradiates the frozen surface and thereby releases materials in a gas cloud, by a process of desorption. The laser w... | 09/18/2007 |
| 7262836 | Apparatus for measuring biological information and method for measuring biological information In order to solve the problem of a prior art biological attribute measuring device, i.e., measurement data is apt to vary because of unstable contact due to difficulty in controlling a thickness of a saliva layer and pain caused during the measurement, is provided a... | 08/28/2007 |
| 7259017 | Method of diagnosing lubricated portion and system of diagnosing lubricated portion The invention provides a method of diagnosing a lubricated portion which can precisely measure a metal concentration in a lubricating oil and can diagnose accurately a state of the lubricated portion on the basis of a value of measurement. In accordance with the pre... | 08/21/2007 |
| 7259840 | Fluid analysis apparatus A fluid analysis apparatus for containing and analyzing a fluid sample includes a cell body assembly having a plurality of distinct portions in fluid communication with one another and with the distinct portions being hydraulically sealed to one another through the ... | 08/21/2007 |
| 7256882 | Photometer device and method A photometer device including an inlet passage for receiving a fluid such as an aerosol at a specified flow rate, an outlet passage separated from the inlet passage by a gap, and a radiation passage across the gap. The flow rate and the significant dimension of the ... | 08/14/2007 |
| 7253005 | Catalyst sampling system A method and apparatus are provided for obtaining a reproducible sample of solid particles. The reproducible sample is obtained by receiving solid particles into a collection system that includes a sheltered volume. Solid particles that settle outside of the shelter... | 08/07/2007 |
| 7248346 | Apparatus for defining orientation of an alignment layer in a pixel unit of an LCD device and the method thereof An apparatus for determining orientation of an alignment layer in a pixel unit of an LCD device is provided. The pixel unit includes a glass substrate having an outer surface provided with the alignment layer treated by photolithographic masking and rubbing operatio... | 07/24/2007 |
| 7244396 | Method for preparation of microarrays for screening of crystal growth conditions A method of screening solution conditions suitable for the crystallization of macromolecules with a picogram to a microgram of protein using picoliter or nanoliter volumes is provided. A preferred method comprises preparing a plurality of recipe solutions in millili... | 07/17/2007 |
| 7242474 | Cytometer having fluid core stream position control A cytometer having two or more chambers or regions in a containment structure of sheathing fluid that may be used to provide hydrodynamic focusing of another fluid having particles to be observed. The latter fluid may be a core stream which may have its lateral posi... | 07/10/2007 |
| 7241569 | Method and a device for the evaluation of biopolymer fitness A Method for identifying one or a small number of molecules, especially in a dilution of ≦1 μM, using laser excited FCS with measuring times ≦500 ms and short diffusion paths of the molecules to be analyzed, wherein the measurement is performed in small volume ... | 07/10/2007 |
| 7236236 | Methods for detecting malaria parasites and reagent kits therefor Methods for detecting a malaria parasite are described that include: releasing the malaria parasite by allowing an erythrocyte in a specimen to undergo hemolysis; staining the released malaria parasite with a fluorescent dye to prepare a measurement sample; detectin... | 06/26/2007 |
| 7224475 | Methods and apparatus for measurement of a dimensional characteristic and methods of predictive modeling related thereto A method of optically determining a change in magnitude of at least one dimensional characteristic of a sample in response to a selected chamber environment. A magnitude of at least one dimension of the at least one sample may be optically determined subsequent to a... | 05/29/2007 |
| 7224452 | Method of exciting molecules out of a first state into a second states using an optical signal In a fluorescence-microscopic method of examining a sample with high spatial resolution, the sample is first cooled to a temperature of below 5° C.; next the cooled sample is transferred out of a ground state into a fluorescent state within an area captured by a de... | 05/29/2007 |
| 7221445 | Methods and apparatus for detecting and quantifying surface characteristics and material conditions using light scattering A system for quantifying surface characteristics detects and quantifies characteristics of a surface of an object. For example, the system may quantify changes in surface roughness without contacting the specimen and without requiring precise temporal or spatial sta... | 05/22/2007 |
| 7221453 | Optical apparatus Various optical apparatus provide a source of parallel light (7, 75). The parallel light (7, 75) is generally achieved by directing an incident beam at the apex of a prism (1, 22, 24, 26, 28). The prism may have varying configurations. One confi... | 05/22/2007 |
| 7205560 | Method and apparatus for processing a micro sample An object of the invention is to realize a method and an apparatus for processing and observing a minute sample which can observe a section of a wafer in horizontal to vertical directions with high resolution, high accuracy and high throughput without splitting any ... | 04/17/2007 |
| 7205554 | Method and apparatus for processing a micro sample An object of the invention is to realize a method and an apparatus for processing and observing a minute sample which can observe a section of a wafer in horizontal to vertical directions with high resolution, high accuracy and high throughput without splitting any ... | 04/17/2007 |
