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Felix Hoffmann, a German chemist, was searching for something to relieve his father's arthritis. In doing so, he "rediscovered" acetylsalicylic acid and in 1900, patented a stable process for developing it. Hence, we have aspirin.
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| Number | Title | Issue Date |
| 8167427 | Multifocal contact lenses manufactured from a responsive polymer gel A multi-focal contact lens wherein the lens is manufactured at least partially from a responsive polymer gel. ... | 05/01/2012 |
| 8118426 | Corneal-sclera orthokeratology lens with asymetric blends A corneal-scleral orthokeratology contact lens is formed of rigid gas permeable material with uniform arc lengths in the treatment area even when the corneal curvature varies and asymmetric blends or splines called minor zones, where the portion of the blend or spli... | 02/21/2012 |
| 8113652 | Contact lens with meridional sagittal variation and methods for making and using the same The present invention is directed toward the design of lenses to incorporate elevation features in at least one annular zone on the posterior surface of the lens that engage the elevation differences of the eye while allowing the central zone of the lens to have con... | 02/14/2012 |
| 8100528 | Coating solutions comprising segmented interactive block copolymers This invention is directed toward surface treatment of a device. The surface treatment comprises the attachment of interactive segmented block copolymers to the surface of the substrate by means of interactive functionalities of the segmented block copolymer reactin... | 01/24/2012 |
| 8083348 | Biomedical devices Biomedical devices such as contact lenses formed from a polymerization product of a mixture comprising an ethylenically unsaturated-containing non-amphiphilic macromonomer comprising hydrophilic units or hydrophobic units derived from a living radical polymerization... | 12/27/2011 |
| 8079703 | Silicone-containing polymeric materials with hydrolyzable groups The invention provides a silicone hydrogel contact lens including a hydrolyzable units. The hydrolyzable units can be converted by hydrolysis into a hydrophilic units which is capable of imparting the silicone hydrogel contact lens a hydrophilic surface without post... | 12/20/2011 |
| 7934830 | High water content silicone hydrogels Silicone hydrogels formed from a hydrated polymerization product of a monomer mixture comprising (a) a major amount of a non-silicone-containing hydrophilic monomer; and (b) a minor amount of a silicone-containing monomer, wherein the hydrogel has a water content of... | 05/03/2011 |
| 7866814 | Toric lens design This invention is related to contact lenses. In particular, the present invention is related to a toric contact lens design with thickness zones in the carrier portion of the lens for increased rotational stability. ... | 01/11/2011 |
| 7857447 | Interpenetrating polymer network hydrogel contact lenses The present invention provides interpenetrating polymer network hydrogels that have high oxygen permeability, strength, water content, and resistance to protein adsorption. The hydrogels include two interpenetrating polymer networks. The first polymer network is bas... | 12/28/2010 |
| 7832857 | Microbial cellulose contact lens The present invention provides a contact lens from Gluconacetobacter xylinus cellulose material. ... | 11/16/2010 |
| 7828432 | Hybrid contact lenses prepared with expansion controlled polymeric materials A hybrid contact lens includes a substantially rigid center portion and a substantially flexible skirt portion connected to the center portion. The skirt portion is formed using xerogels compatible with diluents comprising at least one selected from polylactic acid,... | 11/09/2010 |
| 7828431 | Junctionless ophthalmic lenses and methods for making same Methods for producing a junctionless ophthalmic lens are provided. Additionally, ophthalmic lenses having junctionless, three dimensional surfaces, for example, asymmetrical anterior and/or posterior surfaces, as well as molding tools used in the production of such ... | 11/09/2010 |
| 7798639 | Method for applying lubricious coating to a polymeric article The present invention provides a medical device, preferably an ophthalmic device, more preferably a contact lens, which comprises a lubricious coating including a capping layer of polyvinylpyrrolidone and/or at least one layer of a lubricious coating material and on... | 09/21/2010 |
| 7789507 | Facilitating release of silicone hydrogel ophthalmic lenses This invention includes methods and systems for processing hydrogel biomedical devices, such as ophthalmic lenses using polyethylene glycol to facilitate release of the devices from a mold part. ... | 09/07/2010 |
| 7726809 | Contact lens, method for producing same, and pack for storage and maintenance of a contact lens A contact lens (4) comprises a solid component capable of imparting shape and structure to said lens, and a liquid component, at least partially contained in the solid component, capable of favoring the compatibility between said lens and the eye of a user of... | 06/01/2010 |
| 7699464 | Hydrodynamically operated multifocal contact lens This invention details a contact lens that uses a reservoir of fluid compressed by the lower lid to dynamically shift the refractive power of the lens. This creates a lens that has a plurality of focal points depending on the position of gaze. This can be accomplish... | 04/20/2010 |
| 7682019 | Methods for rotationally stabilizing contact lenses The invention provides contact lenses which have improved dynamic stabilization and that utilize one or more thin zones in the lens' periphery. ... | 03/23/2010 |
| 7658493 | Contact lens, method for producing same, and pack for storage and maintenance of a contact lens A contact lens (4) comprises a solid component capable of imparting shape and structure to said lens, and a liquid component, at least partially contained in the solid component, capable of favoring the compatibility between said lens and the eye of a user of... | 02/09/2010 |
| 7628485 | Contact lens having a uniform horizontal thickness profile A contact lens having a rotational stabilization mechanism thereon, such as prism ballast, and a thickness profile that reduces the torque imparted on the lens by the action of the eyelids, especially for stabilizing toric lenses. The prism ballast is provided on on... | 12/08/2009 |
| 7625084 | Contact lens A contact lens having a rotational stabilization mechanism thereon, such as a prism ballast, and a thickness profile that reduces the torque imparted on the lens by the action of the eyelids, especially for stabilizing toric lenses. The prism ballast is provided on ... | 12/01/2009 |
| 7618142 | Contact lenses A contact lens having a rotational stabilization mechanism thereon, such as prism ballast, and a thickness profile that reduces the torque imparted on the lens by the action of the eyelids, especially for stabilizing toric lenses. The prism ballast is provided on on... | 11/17/2009 |
| 7588334 | Contact lens A contact lens excellent in optical property, offering favorable feeling during the use thereof, and capable of continuous uses, which is composed of a hard portion in the central part and a soft portion in the periphery of the central part is provided. The contact ... | 09/15/2009 |
| 7585074 | Hybrid contact lens system and method A hybrid contact lens comprises a central zone comprising a substantially rigid, gas permeable material having a DK of at least 30, a relatively soft peripheral zone and an intermediate zone comprising a film or coating that is created around the central zone, and t... | 09/08/2009 |
| 7559649 | Corneal-scleral orthokeratology contact lens A corneal-scleral orthokeratology contact lens is formed of rigid gas permeable material with uniform arc lengths in the treatment area even when the corneal curvature varies and asymmetric blends or splines called minor zones, where the portion of the blend or spli... | 07/14/2009 |
| 7556375 | Soft lens orthokeratology A corneal reshaping by means of a soft contact lens to manipulate tear pressure gradient to produce a dimensional change to the surface profile of the cornea of the wearer to provide at least a temporary change in the refractive state of the eye eliminating the need... | 07/07/2009 |
| 7461937 | Soft contact lenses displaying superior on-eye comfort The present invention relates to soft contact lenses having an overall comfort preference of at least about 2 to 1 as compared to an Acuvue® contact lens and measured after one week of daily wear. The present invention further relates to a soft contact lens compris... | 12/09/2008 |
| 7434930 | Contact lens design for large amplitude translation The present invention is directed to a contact lens design where the optics position relative to the pupil is controlled by the lens relationship to the lower lid. ... | 10/14/2008 |
| 7431152 | Hydrogel contact lenses and package systems and production methods for same Contact lenses ready for use in an eye are provided including a contact lens body containing a hydrophilic polymeric component and a water soluble polymer component. Such contact lenses, which preferably are wet cast molded, are particularly useful as disposable or ... | 10/07/2008 |
| 7399795 | Surface modification of contact lenses Provided are surface modified contact lenses formed from one or more fumaric- or itaconic-containing prepolymers having reactive functionality that is complimentary to reactive hydrophilic polymers. ... | 07/15/2008 |
| 7377637 | Hybrid contact lens system and method of fitting A hybrid contact lens comprises a substantially rigid zone having an aspheric base curve with a given apical radius and a substantially flexible hydrophilic peripheral portion coupled to the substantially rigid zone, the peripheral portion having one of a plurality ... | 05/27/2008 |
| 7368589 | Purification of silicone containing compounds by supercritical fluid extraction The present invention relates to a process for the purification of silicone containing compounds via supercritical fluid extraction. Specifically, the present invention relates to a process comprising the steps of contacting at least one silicone containing compound... | 05/06/2008 |
| 7368072 | Photochromic contact lenses and methods of manufacturing Described are contact lenses having photochromic materials within the central or pupillary area of the lens and methods for manufacturing such lenses. In one method, a photochromic amount of at least one photochromic material is added to the pupillary region of a ca... | 05/06/2008 |
| 7354900 | Treatment and inhibition of ocular infections and wounds by CAP37 and CAP37 peptides A method for treating ocular conditions such as bacterial keratitis, bacterial conjunctivitis, corneal ulcers and wounds, endophthalmitis, and blebitis in mammals, by using a native, synthetic, or recombinant CAP37, or effective peptide portions thereof including CA... | 04/08/2008 |
| 7354151 | Ring laser photocoagulation An improved ophthalmic fundus contact lens to observe and irradiate the interior of the eye. Internally the device consists of a ring of contiguous mirrors (12) with identical angulations arranged around a posterior concave lens (10). The outside surfa... | 04/08/2008 |
| 7351787 | Process for the preparation of activated polyethylene glycols A process for preparing activated polyethylene glycols is disclosed. In some embodiments, the process includes reacting a molten polyethylene glycol with an activator. In other embodiments, the process includes reacting a polyethylene glycol with an activator in the... | 04/01/2008 |
| 7329001 | Methods for improving the hydrophilicity of contact lenses and contact lenses having the same The present invention relates to contact lenses manufactured using a gas permeable material with improved hydrophilicity. A method for improving the hydrophilicity of the contact lens includes providing a contact lens comprising a gas permeable contact lens material... | 02/12/2008 |
| 7322694 | Hybrid contact lens system and method A hybrid contact lens comprises a central zone comprising a substantially rigid, gas permeable material having a DK of at least 30, a relatively soft peripheral zone and an intermediate zone comprising a film or coating that is created around the central zone, and t... | 01/29/2008 |
| 7303277 | Multifocal contact lens A contact lens formed from a transparent material having front and rear surfaces, wherein the rear surface has a base curve which is adapted to fit an eye of a wearer of the lens. The front surface has a central zone which has two different cylindrical curvatures wh... | 12/04/2007 |
| 7297725 | Biomedical devices having improved surface characteristics Biomedical devices, such as ophthalmic lenses, and methods of making such devices having a surface coating including at least one polyionic layer. A preferred method involves spray coating a polycationic material onto a core lens, rinsing and drying the lens, follow... | 11/20/2007 |
| 7295376 | Pseudo cross-link type resin composition, molding material, sheet or film, and optical element obtained therefrom A pseudo cross-link type resin composition made of one of resins or a mixture of the resins; wherein the resin is obtained by mixing a polymer molecule that has an atomic group capable of forming an intermolecular hydrogen bond at least in a molecular side ch... | 11/13/2007 |
