Glam girl Heddy Lamar may have used her good looks to good effect on the silver screen, but she put her smarts to better use as an inventor. During World War II, she co-patented a frequency-switching system for torpedo guidance that was considered years ahead of its time.
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| Number | Title | Issue Date |
| 8143600 | 3D imaging of live cells with ultraviolet radiation A method for 3D imaging of cells in an optical tomography system includes moving a biological object relatively to a microscope objective to present varying angles of view. The biological object is illuminated with radiation having a spectral bandwidth limited to wa... | 03/27/2012 |
| 8053744 | Location analysis using nucleic acid-labeled tags A method for using information encrypted with a nucleic acid molecule to backtrack an item's path or identify a point of origin. Unique nucleic acid-containing tags are seeded at one or more geographic locations. Using sequence analysis techniques, the person or obj... | 11/08/2011 |
| 8022373 | Observing apparatus An observing apparatus includes: a photographic unit that takes a region where cells are present as an observation object region based upon a macro image captured at low magnification of an interior of a cell culture vessel, and photographs the cells in the observat... | 09/20/2011 |
| 7932504 | Microscope system and VS image production and program thereof A whole specimen image generated in the bright view field observation method is displayed, and arbitrary domains are designated. And the fluorescence VS image of each object of interest is generated by acquiring the shape of microscopic image for every small block w... | 04/26/2011 |
| 7812324 | Fluorescence detection A fluorescence detection system comprises a light source (22), dichroic mirror (32), excitation port (16), emission port (14), and a detector. The light source (22) is, for example, a pulsed ultraviolet LED, with a light emission t... | 10/12/2010 |
| 7750316 | Polymer biochip for detecting fluorescence This present disclosure provides an optical chip for fluorescence detection. The optical chip has one or more parabolic optical elements that capture and collimate the fluorescent light and direct it onto a detector. The optical chip may be constructed of a polymer ... | 07/06/2010 |
| 7646002 | Fluorescence detecting system A fluorescence detecting system includes a stimulating light projector which projects onto an object part which has been dosed with a fluorescence agent first stimulating light in the exciting wavelength range of the fluorescence agent and second stimulating light w... | 01/12/2010 |
| 7622723 | System for spore detection A method for detecting the presence of bacterial spores in a sample comprises non-destructively to the spores carrying out the steps of assessing the fluorescence of the sample, subjecting the sample to UV radiation, and reassessing the fluorescence of the sample to... | 11/24/2009 |
| 7615762 | Method and apparatus for low quantity detection of bioparticles in small sample volumes A novel apparatus and method is described for detection of very small quantities (a few hundred molecules) of bioparticles in nanoliter/picoliter quantities of a sample. The apparatus involves a very small and low cost apparatus that contains a fluorometer. The dete... | 11/10/2009 |
| 7612350 | Scanning microscope and specimen image obtaining method in which adjacent data obtaining points are not consecutively obtained A scanning microscope includes a light source unit that projects laser light, an optical system that converges and applies the laser light onto data obtaining points on a specimen, and a data obtaining order deciding unit that decides a data obtaining order such tha... | 11/03/2009 |
| 7528384 | Methods and devices for characterizing particles in clear and turbid media The invention provides methods and devices for detecting, identifying, classifying and characterizing particles in a fluid sample. Optical analyzers are provided having a rotating and/or translating sample container for measuring the concentrations of fluorescent pa... | 05/05/2009 |
| 7511285 | Methods and apparatus for biomolecule identification The apparatus and methods described herein provide improved resolution, high-throughput, biomolecule identification by exciting sub-wavelength regions of biomolecules drawn through a microfluidic channel. ... | 03/31/2009 |
| 7495236 | Apparatus and method for detection with a scanning microscope An apparatus and a method for detection with a scanning microscope (1) are disclosed. The scanning microscope (1) encompasses a scanning device (7) that guides an illuminating light beam (3) through a scanning optical system (12) a... | 02/24/2009 |
| 7420674 | Method and arrangement for analyzing samples A method and/or arrangement for the analysis of fluorescing samples in an image-generating microscope system, preferably a laser scanning microscope, wherein the sample is scanned point-by-point or line-by-line in at least one surface section and a dispersive splitt... | 09/02/2008 |
| 7410793 | Optical instrument including excitation source An optical instrument is provided for simultaneously illuminating two or more spaced-apart reaction regions with excitation beams generated by a light source. The light source can include an area light array of light emitting diodes, one or more solid state lasers, ... | 08/12/2008 |
| 7387891 | Optical instrument including excitation source An optical instrument is provided for simultaneously illuminating two or more spaced-apart reaction regions with an excitation beam generated by a light source. A collimating lens can be disposed along a beam path between the light source and the reaction regions to... | 06/17/2008 |
| 7375348 | Micro UV detector A biological aerosol detector is provided. The biological aerosol detector uses a semiconductor optical source with an ultraviolet emission band to excite biological molecules in an aerosol sample. Filtering optics are configured to attenuate radiation from a second... | 05/20/2008 |
| 7371517 | High purity X-chromosome bearing and Y-chromosome bearing populations of spermatozoa Isolated non-naturally occurring populations of spermatozoa (15) having high purity and technologies to differentiate spermatozoa (28) based on characteristics such as mass, volume, orientation, or emitted light including methods of analysis and appara... | 05/13/2008 |
| 7371564 | Apparatus for automatically analyzing genetic and protein materials using photodiodes An apparatus for automatically analyzing genetic and protein materials using photodiodes. The apparatus comprises a computer for controlling the entire operation of the apparatus and analyzing a voltage level from a characteristic detector to analyze states of the g... | 05/13/2008 |
| 7365344 | Scanning fluorescent microscope A scanning fluorescent microscope includes a light source which irradiates a sample with an exciting light pulse, and a splitter which splits fluorescent photons emitted from the sample excited by the exciting light pulse, in at least first and second groups. The sc... | 04/29/2008 |
| 7333195 | Method for detecting photosynthesis inhibition This invention relates to a method for detecting the photosynthesis-inhibitory activity of substances by providing cells or cell parts with an intact photosystem, introducing the cells or cell parts into a planar layer, applying the test substance to the planar laye... | 02/19/2008 |
| 7330574 | Best-focus estimation by lateral scanning The sample stage of an array microscope is tilted in the scanning direction such that the best-focus plane of the array microscope intersects the surface of the sample during the scan. As a result of the tilt, the distance from the sample surface of each miniaturize... | 02/12/2008 |
| 7328059 | Imaging of light scattering tissues with fluorescent contrast agents A system and method for non-invasive biomedical optical imaging and spectroscopy with low-level light is described. The technique includes a modulated light source coupled to tissue to introduce excitation light. Fluorescent light emitted in response to the excitati... | 02/05/2008 |
| 7326938 | Optical system and method for inspecting fluorescently labeled biological specimens A system for imaging a fluorescently labeled sample is presented, The system comprises a capsule, which is a closable structure made of a material isolating the inside of the capsule from its surrounding environment, and which has a support stage for receiving the s... | 02/05/2008 |
| 7328060 | Cancer detection and adaptive dose optimization treatment system The present invention utilizes a series of optical and electronic elements to detect and image cancerous and/or pre-cancerous cells in living tissue. The invention further uses the images thus obtained to adaptively and dynamically shape a treatment light beam so as... | 02/05/2008 |
| 7324668 | Feature extraction in beauty analysis A method of performing a beauty analysis is disclosed. The method comprises receiving information of at least one portion of a subject's external body condition, identifying in the information at least one condition, extracting from the information at least one feat... | 01/29/2008 |
| 7323696 | Phosphor particle coded beads Beads coded with phosphor particles and methods of making and using them are provided. ... | 01/29/2008 |
| 7319039 | Aerosol-based detection of biological agents The presence of an aerosol or cloud (3) of a toxic substance is detected by producing an aerosol (17, 5) of ligands (13) to the target substance in a region of sky that contains the target substance, permitting molecules the target substance to ... | 01/15/2008 |
| 7312448 | Method and apparatus for quantitative three-dimensional reconstruction in scanning electron microscopy A method and an apparatus are for three-dimensional tomographic image generation in a scanning electron microscope system. At least two longitudinal marks are provided on the top surface of the sample which include an angle therebetween. In consecutive image recordi... | 12/25/2007 |
| 7310547 | Fluorescent fiberoptic probe for tissue health discrimination A system and method for the in situ discrimination of healthy and diseased tissue. A fiberoptic based probe is employed to direct ultraviolet illumination onto a tissue specimen and to collect the fluorescent response radiation. The response radiation is observed at... | 12/18/2007 |
| 7309867 | Methods and apparatus for characterization of tissue samples The invention provides methods for determining the probability that a given region of a tissue sample contains tissue of a given category, such as CIN 1 (cervical intraepithelial neoplasia, grade 1), CIN 2/3 (cervical intraepithelial neoplasia grades 2 and/or 3), no... | 12/18/2007 |
| 7306942 | Endospore detector The invention herein provides for the detection of certain calcium containing endospores, and particularly pertains to the detection of bacillus anthracis by first chelating calcium ions of said endospores and then reacting the chelated calcium ions with aequorin to... | 12/11/2007 |
| 7304741 | Pesticide detector and method Highly portable, handheld instrument which can be pointed at the produce to be checked. Light from a source within the instrument is directed onto the produce to induce fluorescent emission from the produce, and fluorescent emissions from the produce are monitored w... | 12/04/2007 |
| 7304315 | Three dimensional analyzing device A three-dimensional analyzing device includes a first beam source for generating a first beam, a second beam source for generating a second beam, an optical system for spatially overlapping the first and second beams at least partly and irradiating the beams onto a ... | 12/04/2007 |
| 7301626 | Laser-scanning examination apparatus The invention reduces the loss of fluorescence intensity obtained from a specimen to acquire clear fluorescence images when irradiating the specimen with ultrashort-pulse laser light produced by a laser light source. The invention provides a laser-scanning examinati... | 11/27/2007 |
| 7302289 | Readable probe array for use A disposable high density optically readable polydeoxynucleotide array with integral fluorescence excitation and fluorescence emission channels is described. The compact array size allows integration into several types of interventional devices such as catheters, gu... | 11/27/2007 |
| 7294826 | Bio-sensing apparatus A multi-channel sensor is provided with sensor sections, each of the sensor sections reflecting or transmitting light, whose physical characteristics vary for different kinds of samples. Each of samples is supported by one of the sensor sections. A scanning mirror s... | 11/13/2007 |
| 7285789 | Optical device for surface-generated fluorescence A sample substrate adapted for use with electromagnetic excitation light includes a base and a layer system. The layer system includes a multilayer interference coating with at least two layers wherein the thicknesses of the layers ensure that light emitted by a flu... | 10/23/2007 |
| 7282723 | Methods and apparatus for processing spectral data for use in tissue characterization The invention provides methods for processing tissue-derived spectral data for use in a tissue classification algorithm. Methods of the invention comprise application of spectral and/or image masks for automatically separating ambiguous or unclassifiable spectral da... | 10/16/2007 |
| 7274027 | Scanning systems and methods with time delay sensing Methods and systems that excite a test structure with an excitation beam and then sense the response of the test structure after some prescribed time interval with respect to the excitation. One or more detectors detect an emission from the test structure at a locat... | 09/25/2007 |