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| Number | Title | Issue Date |
| 8093552 | Electric field separator device and process A process and device is provided for the separation of electronegative molecules from non electronegative molecules using electric fields. The molecules are ionized in a non thermal discharge plasma which produces negative and positive ions of the electronegative an... | 01/10/2012 |
| 8049167 | Pneumatic ion beam focusing in high-field asymmetric waveform ion mobility spectrometry (FAIMS) A FAIMS device for separating ions has a pair of electrodes for providing a compensation voltage and an asymmetric waveform that are separated and insulated where at least one porous spacer reside in the proximity of the analyzer region of the FAIMS cell. The porous... | 11/01/2011 |
| 7858931 | Methods and devices for the mass-selective transport of ions A method for the mass-selective transport of ions, especially in a mass spectrometer, comprises the steps movement of the ions on a movement path on which a plurality of electrodes are arranged, and loading the electrodes with pulse-shaped acceleration voltages unde... | 12/28/2010 |
| 7851745 | Flat plate FAIMS with lateral ion focusing A high field asymmetric waveform ion mobility spectrometer (FAIMS) includes at least two focusing electrodes that are separated one from the other by a gap, which decreases in width along a direction of ion flow. Within the gap is disposed an electrode assembly incl... | 12/14/2010 |
| 7838823 | Ion mobility spectrometer with virtual aperture grid An ion mobility spectrometer does not require a physical aperture grid to prevent premature ion detector response. The last electrodes adjacent to the ion collector (typically the last four or five) have an electrode pitch that is less than the width of the ion swar... | 11/23/2010 |
| 7777180 | Ion mobility spectrometry method and apparatus The invention includes an ion mobility spectrometer having a liquid filled drift chamber. The chamber has an ionization region partitioned from and an ion separation region by a reversible ion-migration block. An electrical field within the chamber allows ions to mi... | 08/17/2010 |
| 7675031 | Auxiliary drag field electrodes Auxiliary electrodes for creating drag fields may be provided as arrays of finger electrodes on thin substrates such as printed circuit board material for insertion between main RF electrodes of a multipole. A progressive range of voltages can be applied along lengt... | 03/09/2010 |
| 7663099 | Apparatus and method for generating an ammonia gas Apparatus and method for generating ammonia gas. In one aspect, a method for generating ammonia gas for use in an ion mobility spectrometry (IMS) system is provided. The method includes inserting a device into a space defined within the IMS system, the device includ... | 02/16/2010 |
| 7619213 | Ion extraction pulser and method for mass spectrometry The invention provides an ion extraction pulser. The ion extraction pulser may be used independently or in conjunction with a mass spectrometry system. The mass spectrometry system includes an ion source for producing ions, an ion optics system downstream from the i... | 11/17/2009 |
| 7576320 | Photoelectric ion source photocathode regeneration system An explosive detection system based on an ion mobility spectrometer detects the presence of trace molecules in air. Such instruments require an ion source to ionize the trace molecules. An ion source that does not require a radioactive source to operate can use the ... | 08/18/2009 |
| 7576321 | Multidimensional ion mobility spectrometry apparatus and methods Various embodiments of a multi-dimensional ion mobility analyzer are disclosed that have more than one drift chamber and can acquire multi-dimensional ion mobility profiles of substances. The drift chambers of this device can, for example, be operated under independ... | 08/18/2009 |
| 7547879 | Longitudinal field driven ion mobility filter and detection system An asymmetric field ion mobility spectrometer for filtering ions via an asymmetric electric field, an ion flow generator propulsing ions to the filter via a propulsion field. ... | 06/16/2009 |
| 7538320 | Ion detection device and method with compressing ion-beam shutter An ion detection device, method and computer readable medium storing instructions for applying voltages to shutter elements of the detection device to compress ions in a volume defined by the shutter elements and to output the compressed ions to a collector. The ion... | 05/26/2009 |
| 7518106 | Ion mobility spectrometers and methods for ion mobility spectrometry An ion mobility spectrometer may include an inner electrode and an outer electrode arranged so that at least a portion of the outer electrode surrounds at least a portion of the inner electrode and defines a drift space therebetween. The inner and outer electrodes a... | 04/14/2009 |
| 7518105 | Continuous sampling ion mobility spectrometers and methods therefor An ion mobility spectrometer may include a flow channel having an inlet end and an outlet end. A deflection electrode is positioned within the flow channel so that a non-linear electric field is created between at least a portion of the flow channel and at least a p... | 04/14/2009 |
| 7498570 | Ion mobility spectrometer An ion mobility spectrometer is described having an ion filter in the form of multiple parallel ion channels defined by conductive layers separated by non-conductive layers. A time-varying electric potential applied to the conductive layers allows the filter to sele... | 03/03/2009 |
| 7470898 | Monitoring drinking water quality using differential mobility spectrometry Continuous monitoring of fluid composition, e.g. drinking water supply, with improved detection sensitivity and selectivity to varying degrees of contamination at and below the predetermined maximum contaminant levels using pyrolysis-differential mobility spectromet... | 12/30/2008 |
| 7435950 | Micromachined field asymmetric ion mobility filter and detection system A micromechanical field asymmetric ion mobility filter for a detection system includes a pair of spaced substrates defining between them a flow path between a sample inlet and an outlet; an ion filter disposed in the path and including a pair of spaced filter electr... | 10/14/2008 |
| 7435970 | Beam current meter It is possible to simplify the cooling mechanism of a superconductor, significantly reduce the cost, simplify the measurement work, and reduce the time required for measurement. A beam current meter includes: a cylindrical super conductor beam current sensor arrange... | 10/14/2008 |
| 7435949 | Mass spectrometric analysis method and system using the method A tandem analysis system is provided for ionizing a substance, performing mass spectrometric analysis of various ion types generated, selecting and dissociating an ion type, the ion type having a specific mass-to-charge ratio, and thereby, repeating mass spectrometr... | 10/14/2008 |
| 7430871 | NMR spectrometer with a common refrigerator for cooling an NMR probe head and cryostat An NMR spectrometer comprising a magnet coil system disposed in the helium tank (8) of a cryostat and an NMR probe head (4) which is disposed in a room temperature bore of the cryostat and contains a cooled RF resonator (13) for receiving NMR si... | 10/07/2008 |
| 7429729 | Multi-beam ion mobility time-of-flight mass spectrometer with bipolar ion extraction and zwitterion detection The present invention relates generally to instrumentation and methodology for the characterization of chemical samples in solutions or on a surface which is based on modified ionization methods with or without adjustable pH and controllable H-D exchange in solution... | 09/30/2008 |
| 7429731 | Method and device for non-contact sampling and detection A system for the stand-off detection of trace amounts of analyte materials such as explosives, chemical warfare agents, toxic industrial chemicals, and the like includes an ion source that is operably connected to an ion collection means and to a sensor. The ion sou... | 09/30/2008 |
| 7429730 | SIFT-MS instruments A SIFT or SIFDT apparatus in which the upstream quadrupole and the downstream quadrupole are housed within a single evacuated chamber with the upstream quadrupole being connected to the downstream quadrupole by a curved flow tube. In a preferred form the interior of... | 09/30/2008 |
| 7423259 | Mass spectrometer and method for enhancing dynamic range A mass spectrometer comprises an ion detector, a first amplifier, a second amplifier, and a spectra combiner. The ion detector is configured to generate an analog signal indicative of ions detected by the ion detector. The first amplifier is configured to amplify th... | 09/09/2008 |
| 7417222 | Correlation ion mobility spectroscopy Correlation ion mobility spectrometry (CIMS) uses gating modulation and correlation signal processing to improve IMS instrument performance. Closely spaced ion peaks can be resolved by adding discriminating codes to the gate and matched filtering for the received io... | 08/26/2008 |
| 7417223 | Method, system and computer software product for specific identification of reaction pairs associated by specific neutral differences A first mass spectrum and a second mass spectrum of the same ion sample can be analyzed to determine reaction pairs. These reaction pairs are determined based on a selected neutral difference by shifting the second mass spectrum by the neutral difference relative to... | 08/26/2008 |
| 7417224 | Ion mobility spectrometer with parallel drift gas and ion carrier gas flows An ion mobility spectrometer is provided with at least one ionization chamber (1) through which analyte-containing gas can flow. A radiation source (2) is provided from which ionizing radiation is suitable for ionizing the analyte-containing gas at lea... | 08/26/2008 |
| 7414242 | Ion mobility spectrometry method and apparatus The invention includes an ion mobility spectrometer having a liquid filled drift chamber. The chamber has an ionization region partitioned from and an ion separation region by a reversible ion-migration block. An electrical field within the chamber allows ions to mi... | 08/19/2008 |
| 7408151 | Dynamic biasing of ion optics in a mass spectrometer A device for dynamically biasing an ion optic element, for example, in a mass spectrometer. The device includes a voltage source, a first ion optical element coupled with the voltage source, a second ion optical element resistively coupled with the first ion optical... | 08/05/2008 |
| 7405398 | Mass spectrometer interface A mass spectrometer interface, having improved sensitivity and reduced chemical background, is disclosed. The mass spectrometer interface provides improved desolvation, chemical selectivity and ion transport. A flow of partially solvated ions is transported along a ... | 07/29/2008 |
| 7399959 | Method and apparatus for enhanced ion based sample filtering and detection The invention provides, in various embodiments, systems and methods relating to enhancing the filtering and detection capability of ion mobility based systems by various techniques to counteract a charge buildup in the ion mobility based system. ... | 07/15/2008 |
| 7399958 | Method and apparatus for enhanced ion mobility based sample analysis using various analyzer configurations A system for analyzing one or more ion species of a sample including a first ion mobility filter associated with a first flow path for passing first ions of the sample, a second ion mobility filter associated with a second flow path for passing second ions of the sa... | 07/15/2008 |
| 7399957 | Coded mass spectroscopy methods, devices, systems and computer program products A coded mass spectrometer incorporates a spatial or temporal code to reduce the resolution/sensitivity dichotomy inherent in mass spectrometry. The code is used to code one or more portions of a mass spectrometer. Coding patterns, such as Hadamard codes, Walsh codes... | 07/15/2008 |
| 7399960 | Time of flight mass spectrometer A time of flight mass spectrometer according to the present invention includes: a) an ion source at which an ion starts flying; b) an energizer for giving a predetermined amount of energy to the ion to let the ion start flying from the ion source; c) an ion guide fo... | 07/15/2008 |
| 7388195 | Apparatus and systems for processing samples for analysis via ion mobility spectrometry The invention provides an interface assembly for delivering an ionized analyte from an ionization apparatus into an ion mobility spectrometer. This allows analysis of biological and non-biological samples, even non-volatile solids, via differential mobility spectrom... | 06/17/2008 |
| 7385188 | Linear electric field time-of-flight ion mass spectrometer A linear electric field ion mass spectrometer having an evacuated enclosure with means for generating a linear electric field located in the evacuated enclosure and means for injecting a sample material into the linear electric field. A source of pulsed ionizing rad... | 06/10/2008 |
| 7381945 | Non-linear time-of-flight mass spectrometer A time-of-flight mass spectrometer has a first electrode, a second electrode spaced apart from the first electrode, a third electrode arranged between the first and second electrodes. The third electrode reserves a space for ions to travel between the first and seco... | 06/03/2008 |
| 7378650 | Ion-mobility spectrometer and ion-mobility analysis method There is provided an ion-mobility spectrometer. This apparatus includes the following configuration components: An ion source for generating first ions, a first drift unit for separating the first ions by flight drift times, an ion dissociation unit for generating s... | 05/27/2008 |
| 7378652 | Nebulizer with plasma source A combination electrospray/microwave induced plasma (MIP) ionization source is used as the ionization source for a mass spectrometer. The electrospray can be operated in positive mode, negative mode, or it can be switched off. The microwave-induced plasma can also b... | 05/27/2008 |
