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Class 250/281 - IONIC SEPARATION OR ANALYSIS


Subclass of Class 250 - Radiant energy
Definition: Subject matter comprising (1) means to select an ion of
No. of patents: 1583
Last issue date: 05/29/2012


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NumberTitleIssue Date
8188423Method and apparatus for ion fragmentation in mass spectrometry
A method for fragmentation of analyte ions for mass spectroscopy and a system for mass spectroscopy. The method produces gas-phase analyte ions, produces gas-phase odd-electron containing species separately from the analyte ions, and mixes the gas-phase analyte ions...
05/29/2012
8188422Fabrication of three-dimensional ion optics assemblies by metallization of non-conductive substrates
A die assembly for creating a ring electrode including a cylindrically-shaped die base, two die walls and a die top sized to fit inside a cylindrical die housing. The die base and die top having a series of concentric elevations used as impressions to form on two en...
05/29/2012
8178833High-flow tube for sampling ions from an atmospheric pressure ion source
An improved ion sampling tube designed to increase the amount of current delivered into the vacuum system of a mass spectrometer or other gas-phase ion or particle detectors or collectors. A device and method is disclosed that utilizes a tube with a high flow of ion...
05/15/2012
8168942Chromatograph mass spectrometer
In a chromatograph mass spectrometer capable of defining an appropriate measurement time range and selectively performing a scan measurement, selected ion monitoring (SIM) measurement or simultaneous scan/SIM measurement in that time range, a total ion chromatogram ...
05/01/2012
8164051Internal standard material, resin composition, and measurement method
An internal standard material to be added to a specimen containing a material to be measured when measuring the content of the material to be measured by performing mass spectrometry on the specimen includes a hindered phenol compound. ...
04/24/2012
8164052Mass spectrometer
A mass spectrometer is disclosed comprising an Electron Transfer Dissociation cell (1). Positive analyte ions are fragmented into fragment ions upon colliding with singly charged negative reagent ions with the cell (1). The cell comprises a plurality o...
04/24/2012
8148675Collision cell for an MS/MS mass spectrometer
The length of the collision cell (20) in the direction along the ion optical axis (C) is set to be within the range between 40 and 80 mm, and typically 51 mm, which is remarkably shorter than before. The CID gas is supplied so that it flows in the direction o...
04/03/2012
8143571Method for fractioning peptides and other compounds
A method for fractionating a target fraction from a sample is disclosed herein. The method includes providing a polymer brush having a substrate and a polymer chain attached to and extending outwardly from the substrate. The method further comprising contacting the ...
03/27/2012
8134119Reflectron
A reflectron (1) for deflecting an ion from a specimen in a time-of-flight mass spectrometer comprises a front electrode (2) and a back electrode (3). At least one of the front and back electrodes (2, 3) is capable of generating a curved ...
03/13/2012
8134120Mass spectrometer
A mass spectrometer with an ionization chamber with a feed channel for a gas to be examined, including an electron source (d, n) for ionizing the gas to be examined, electrodes (c) for accelerating the ionizing electrons, electrodes (g, h, j, m) for the mass-depende...
03/13/2012
8129674Mass spectrometric analyzer
A tandem mass spectrometer comprising an ion source for ionizing a sample, an ion trap section for carrying out collision induced dissociation of the target ions thereby to produce fragment ions, a multi electrode collision section for conducting collision induced d...
03/06/2012
8119981Mass spectrometer
A fault detection system for protecting a mass spectrometer from the effects of temperature extremes. The system comprises an ion block, a thermal source for providing thermal energy to the ion source block, a temperature sensor providing a reading for the temperatu...
02/21/2012
8115165Mass selector
A mass spectrometer and method for performing high resolution mass spectrometry are provided, the mass spectrometer comprising an electrostatic trap and mass analyzer. The electrostatic trap comprises entrance and exit ends, entrance and exit end ion mirrors, a cent...
02/14/2012
8093551Self-aligning floating ion-optics components
A mass spectrometry system includes an ion-optics and a housing for the ion-optics. A panel is movable between an open and closed position relative to the housing. A first section of the ion-optics is within the housing, while a second section of the ion-optics is m...
01/10/2012
8084732Resistive glass structures used to shape electric fields in analytical instruments
A reflectron lens for a time-of-flight mass spectrometer and a method of making same are disclosed. The reflectron lens includes a glass tube having a conductive surface along the length of the tube. The conductive surface has an electrical resistance gradient along...
12/27/2011
8076635Apparatus and method for performing mass spectroscopy
Embodiments of the present invention are directed to apparatus and methods for performing mass spectrometry. Data pair information is subjected to an ion audit process in which data pair information that relates to scored compounds is subtracted from the data pair i...
12/13/2011
8067727Portable composite bonding inspection system
In a surface inspection system for detecting particles on a surface, a light source mounted to illuminate the surface provides multiple wavelength ranges of electromagnetic radiation. An optical detector produces an image of the surface. An optical signal is produce...
11/29/2011
8044343Gas analyzer
A plurality of molecule components included in a gas are to be ionized at the same time by PI method. For instance, a plurality of molecule components included in a gas generated at a certain instance are accurately analyzed in real time based on PI method. A gas an...
10/25/2011
8044344Mass spectroscope
A mass spectroscope includes a mass analysis device having a surface provided with metallic members capable of exciting plasmons when irradiated by laser light, the mass analysis device allowing an analyte to be attached to the surface, a light radiation unit for ir...
10/25/2011
8034567Quantification of gene expression
The present invention relates to a method for measuring the amount of a target nucleic acid in a sample using a standard which is designed to have one base difference compared with the gene of interest or a “target nucleic acid sequence.” Use of such standard in...
10/11/2011
8030610Chemical noise reduction for mass spectrometry
In various aspects, the present teachings provide systems and methods for reducing chemical noise in a mass spectrometry instrument that use a neutral chemical reagent and one or more mass filters to reduce interfering chemical background ion signals that are genera...
10/04/2011
8026475Method and apparatus for a dual gate for a mass spectrometer
An ion gate apparatus for controlling the transmission of ion pulses between an origin and a destination in a mass spectrometer is disclosed, comprising: a first split gate having a length L1, comprising a first electrode portion; and a second electrode p...
09/27/2011
8013290Method and apparatus for avoiding undesirable mass dispersion of ions in flight
In a mass spectrometer a target volume is filled with ions of different mass but substantially the same energy from a distant storage device by forming a plurality of spatially-limited ion swarms consisting of ions having the same mass. The ion swarms are ordered ei...
09/06/2011
7985948Systems and methods for analyzing substances using a mass spectrometer
Systems and methods for analyzing compounds in a sample. In one embodiment, the present technology is directed towards a method of analyzing a sample, comprising: emitting ions from the sample; selecting the emitted ions for a designated ion; fragmenting the designa...
07/26/2011
7982180Methods and systems for analysis and correction of mass spectrometer data
A background component of reporter ion signals is determined by fitting a distribution function. A plurality of samples that include a protein labeled with a plurality of isobaric reporter ions is analyzed at a plurality of different times using a mass spectrometer,...
07/19/2011
7960689Method and system for internal chemical ionization with water in ion trap mass spectrometry
Method and system that allows the use of water as reactant gas for internal chemical ionization in mass spectrometry. The system provides a stable water vapor pressure in the ion trap by condensation-free water vapor flow between water reservoir and ion trap. The sy...
06/14/2011
7956320Data processor for mass spectrometer
A main peak list is created with the data obtained by an MSn analysis (S1), the difference between the mass-to-charge ratio of each product ion listed on this main peak list and that of the precursor ion is calculated (S2), and an auxiliary ...
06/07/2011
7932486Mass spectrometer system
During the structural analysis of a protein or peptide by tandem mass spectroscopy, a peptide ion derived from a protein that has already been measured and that is expressed in great quantities is avoided as a tandem mass spectroscopy target. A peptide derived from ...
04/26/2011
7928361Multiple detection systems
A particle detection system is configured and operated as two or more separate and completely independent detection systems. The detection systems may be of the same or different design, may be operated in the same or different modes, and may be operated with the sa...
04/19/2011
7923680Analysis method and analysis apparatus
An analysis apparatus includes a first process part for removing a film formed on a substrate by irradiating the film with ultraviolet light, a second process part for providing a solution onto a surface of the substrate for dissolving an object being analyzed on th...
04/12/2011
7919745Methods and systems for background correction in tandem mass spectrometry based quantitation
A corrected reporter ion intensity is calculated in tandem mass spectrometry based quantitation using isobaric labels. An analyte in each of two or more samples of a mixture of samples is labeled with a different isobaric label. The analyte is eluted from the mixtur...
04/05/2011
7884317Base line restoration circuit
Circuits for correcting base line shift of the detector coupling circuit of a TOFMS provide gain and impedance characteristics that compensate for the AC coupling effect of the detector. In one circuit, base line correction is achieved by injecting a current equal t...
02/08/2011
7880135Mass spectrometer
The analyst previously enters the mass of a fragment that desorbs in the first dissociation with other analysis conditions, as the precursor ion selection reference for the second dissociation through the input unit 25. When the automatic analysis is started,...
02/01/2011
7872223Mass spectrometer
A laser light is linearly delivered onto the sample 4. The ions generated from the irradiated area are collected, mass-separated in the mass separator 27, and detected by the detector 28. A mass analysis is repeated while moving the sample stage...
01/18/2011
7863556Enhanced resolution mass spectrometer and mass spectrometry method
A mass spectrum is generated by a process in which, from a mass scan signal comprising original samples defining a peak, a subset of the original samples defining the peak is selected. One or more synthesized samples are synthesized from the subset of the original s...
01/04/2011
7863557Mass spectrometer
A multi-turn Time of Plight mass analyzer is disclosed comprising a first electric sector (5) and a second electric sector (8). The second electric sector (8) is arranged orthogonal to the first electric sector (5). Ions may make multiple...
01/04/2011
7858927Apparatus and method for operating a differential mobility analyzer with a mass spectrometer
An apparatus and method of analyzing ions is described in which a Differential Mobility Analyzer (DMA) is combined with an analysis device. The DMS can be operated in first and second modes of operation to produce a plurality of ions that are sampled and analyzed by...
12/28/2010
7858926Mass spectrometry with segmented RF multiple ion guides in various pressure regions
A mass spectrometer includes an ion source and at least one vacuum stage, a means for delivering ions from the ion source to the vacuum stage, a collision cell, a detector, at least two multipole ion guide segments, and independent RF frequency and DC voltage source...
12/28/2010
7855355High-voltage power unit and mass spectrometer using the power unit
The output terminal P2 of the positive voltage generating circuit 2 and the output terminal Q1 of the negative voltage generating circuit 4 are connected in series. The output terminal Q2 of the negative voltage generating circuit ...
12/21/2010
7855356Determination of chemical empirical formulas of unknown compounds using accurate ion mass measurement of all isotopes
A method of determining an empirical formula of an analyte ion from a measured mass spectrum including a main peak and one or more isotope peaks. The method comprises comparing a relative isotopic intensity of the measured isotope peak to a calculated relative isoto...
12/21/2010
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