Celebrity Inventors
Mark Twain (Samuel L. Clemens) received Patent No. 121,992 for "An Improvement in Adjustable and Detachable Straps for Garments." He later received two more patents: one for a self-pasting scrapbook and one for a game to help players remember important historical dates.
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| Number | Title | Issue Date |
| 8182690 | Centrifugal partitioning chromatography device and method implemented by this device The present invention relates to a centrifugal partitioning chromatography device for separating a liquid having at least two phases, and to a centrifugal partitioning chromatography method implemented by this device. A chromatography device according to the inventi... | 05/22/2012 |
| 8137559 | Liquid clarification The present invention relates to liquid clarification. More closely, the invention relates to beverage clarification, such as reduction of colloidal (not microbial) haze-causing substances in beer or related beverages such as wine, juices, flavorings etc. The method... | 03/20/2012 |
| 8137560 | Separation process The present invention relates to a process for separating a target radiolabelled compound from an impurity, apparatus for performing such a process and a removable cassette for use in such apparatus. Also provided are methods for using the target radiolabelled compo... | 03/20/2012 |
| 8137561 | Media for membrane ion exchange chromatography based on polymeric primary amines, sorption device containing that media, and chromatography scheme and purification method using the same Media and devices, such as anion exchangers including such media, wherein the media is a membrane having a surface coated with a polymer such as a polyallylamine. The resulting membrane offers stronger binding of protein impurities and superior removal of host cell ... | 03/20/2012 |
| 8114294 | Multi-layered macromolecules and methods for their use Multi-layered macromolecules wherein the layers are covalently bonded together and wherein the macromolecules are covalently bonded to solid particulate substrates, methods for the preparation of such compositions, and methods for their uses in a multitude of end us... | 02/14/2012 |
| 8092682 | Matrix for separation of polyethers and method of separation The present invention relates to a separation matrix comprised of a support to the surfaces of which polymer chains have been coupled, wherein each polymer chain presents recurring proton-donating groups and at least the surface of the support is substantially hydro... | 01/10/2012 |
| 8092683 | Multi-modal ion exchange chromatography resins The present invention relates to a method of preparing a library of resins which are useful in chromatography, which method comprises creating a diversity of multi-modal ion exchange resins; and providing the diversity in a parallel system in which each resin is pre... | 01/10/2012 |
| 8092681 | Method and device for separating constituents of a liquid feed by liquid-liquid centrifugal chromatography The invention relates to a method for separating constituents of a liquid feed by liquid-liquid centrifugal chromatography and to a device for implementing it. Constituents (A, B) having different partition coefficients such that they are respectively carried along ... | 01/10/2012 |
| 8070950 | Boron-removing agent and boron removal method utilizing xerogel Disclosed is a boron removal method which can remove boron from boron-containing water satisfactorily by using a small amount of a chemical agent, and which generates small amount of precipitate. Also disclosed is a boron-removing agent which is easy to handle and h... | 12/06/2011 |
| 8062526 | Separation of platinum group metals A process for the chromatographic interseparation of rhodium in admixture with at least one base metal from a feed solution includes complexes of these metals. The process includes contacting the solution with at least one chromatographic medium, and eluting one or ... | 11/22/2011 |
| 8048305 | Methods for separating and analyzing anionic compounds Systems, methods and compositions for the purification, separation and analysis of anionic compounds, including polyanionic compounds are disclosed. ... | 11/01/2011 |
| 8043507 | Ion chromatography system using catalytic gas elimination A liquid chromatographic system is provided including catalytically combining hydrogen and oxygen gases in the chromatography eluent stream in a catalytic gas elimination chamber, to form water and thereby reduce the gas content in the eluent stream. Also, a liquid ... | 10/25/2011 |
| 8025803 | Use of a chromatography substrate for reducing the amount of ADAMTS13 in a solution derived from plasma An ion-exchange chromatography support for reducing the ADAMTS13 amount present in a plasma-derived solution containing human von Willebrand factor. The support includes a large-pore, vinyl polymer-type resin bearing DEAE groups, and a buffer including trisodium cit... | 09/27/2011 |
| 8017015 | Monolithic column chromatography Provided herein are methods of liquid column chromatography in which preparative chromatography is performed in-line with analytical chromatography. In particular aspects a monolithic preparative column is used to purify an analyte of interest from a mixture of othe... | 09/13/2011 |
| 8002987 | Stationary phase and column using cucurbituril bonded silica gel, and separation method of taxol using the column Provided are a stationary phase and a column using a cucurbituril-bound silica gel, and a method of separating taxane using the column. The taxane separation method includes: preparing a column for taxane separation, the column being packed with a stationary phase i... | 08/23/2011 |
| 7988859 | Countercurrent tangential chromatography methods, systems, and apparatus This invention relates to a breakthrough in the art of chromatography allowing 1) larger scale of operation; 2) faster processing time; 3) disposability; 4) reduction of media/resin expenses; and 5) a reduction of capital equipment investment. In this invention, the... | 08/02/2011 |
| 7988858 | Method for generating metal chelating affinity ligands The present invention relates to a method for generating at least one polydentate metal chelating affinity ligand, which method comprises the steps of (a) providing at least one scaffold defined by the general formula (I): H2N—(X1 | 08/02/2011 |
| 7976708 | Innovative cut-and-feed operation for enhancing the performance of ion-exchange chromatographic separation The present invention relates to a process of enriching element content in stable isotopes of light elements in ion-exchange chromatography. The process comprises development of band of light elements in a chromatographic column; elution of said band in a discontinu... | 07/12/2011 |
| 7967986 | Process for absorption-based separation of bioparticles from an aqueous suspension A process for adsorption-based separation of bioparticles from an aqueous suspension containing such bioparticles is disclosed which process comprises a) bringing said aqueous suspension into contact with a macroporous cryogel monolith carrying on its surface... | 06/28/2011 |
| 7951297 | Material for chromatography Granulated products are provided and include carbonaceous particles and a carbonized agent or binder. The agent or binder is preferably a synthetic resin, pitch component, or mixture thereof. Packing materials for packing columns used in chromatographic separations ... | 05/31/2011 |
| 7943046 | Methods and systems for on-column protein delipidation Embodiments of the present invention provide a method of chromatographic delipidation comprising separating a lipid-containing sample on a superficially porous stationary phase at greater than about 70° C., at least about 80° C., having at least one mobile phase c... | 05/17/2011 |
| 7922909 | Separation system, components of a separation system and methods of making and using them Permeable polymeric monolithic materials are prepared in a column casing. In one embodiment, the permeable polymeric monolithic materials are polymerized while pressure is applied through a piston having a smooth piston head in contact with the polymerization mixtur... | 04/12/2011 |
| 7922908 | Separation system, components of a separation system and methods of making and using them Permeable polymeric monolithic materials are prepared in a column casing. In one embodiment, the permeable polymeric monolithic materials are polymerized while pressure is applied through a piston having a smooth piston head in contact with the polymerization mixtur... | 04/12/2011 |
| 7871519 | Methods for detection, identification and quantification of impurities Provided is a method comprising introducing a sample comprising a plurality of oligonucleotides into an ion pair high performance liquid chromatography column having a buffered mobile phase and allowing at least a portion of the oligonucleotides to separate; allowin... | 01/18/2011 |
| 7854844 | Detection systems and methods The application describes apparatus and methods using ultrasound transmitted through a chromatography column bed to determine the status of materials in the bed space, particularly during chromatography runs. Detected conditions include the profile of a band of elut... | 12/21/2010 |
| 7850852 | Process for producing amino acid or salt thereof by column technique and production apparatus thereof According to the process for producing amino acid or salt thereof in the present invention, in the adsorption step, an amino acid-containing aqueous solution is fed into a pressure tight column so that a free amino acid is adsorbed on a carbonate-type anion exchange... | 12/14/2010 |
| 7842187 | Removal of bacterial endotoxin in a protein solution by immobilized metal affinity chromatography The present invention relates to the purification of polypeptides and the removal of endotoxin via immobilized metal affinity chromatography (IMAC). More specifically, the invention relates to methods for removing bacterial endotoxin in a protein solution. In specif... | 11/30/2010 |
| 7815803 | Preparation of samples for LC-MS/MS using magnetic particles The present invention provides a novel procedure of preparing samples for analysis by way of mass spectrometry, preferably LC-MS/MS. Accordingly, functionalized magnetic particles with a hydrophobic surface were used for extracting low molecular weight compounds fro... | 10/19/2010 |
| 7815802 | Grafted photo-polymerized monolithic column The present invention relates to the fabrication of a grafted, UV photo-polymerized silica-based monolithic column and the use of such column for the extraction of DNA. In one embodiment, a method is provided for fabricating a silica-based monolithic column, wherein... | 10/19/2010 |
| 7794600 | Purification of nanocrystal solutions by chromatography The present invention relates to a method of processing nanocrystals. The method comprises providing a mixture comprising nanocrystals, contaminants and a first solvent in which the nanocrystals are soluble, and using chromatography to reduce the amount of contamina... | 09/14/2010 |
| 7790037 | Separation of compounds using tagging moieties including varying numbers of repeat units A method of separating compounds, includes: a. tagging at least a first organic compound with a first tagging moiety to result in a first tagged compound; b. tagging at least a second organic compound with a second tagging moiety different from the first tagging moi... | 09/07/2010 |
| 7790038 | Ion exchange porous resins for solid phase extraction and chromatography Embodiments of the present invention are directed to porous resins for solid phase extractions. The resins feature at least one hydrophobic component, at least one hydrophilic component and at least one ion exchange functional group. The resins exhibit superior wett... | 09/07/2010 |
| RE41595 | Antibody purification This invention relates to the application of hydrophobic interaction chromatography combination chromatography to the purification of antibody molecule proteins. ... | 08/31/2010 |
| RE41555 | Antibody purification This invention relates to the application of hydrophobic interaction chromatography combination chromatography to the purification of antibody molecular proteins. ... | 08/24/2010 |
| 7758753 | Method of analyzing optical isomers or method of resolving the same Provided are a method of quickly and simply confirming the success or failure of resolution of optical isomers with the use of a column for resolving optical isomers and a method of simply designing the conditions of the eluent composition under isocratic elution co... | 07/20/2010 |
| 7740763 | Capillary-channeled polymeric fiber as solid phase extraction media Solid phase extraction devices including a plurality of packed nominally aligned capillary-channeled polymeric fibers for use as stationary phase materials are disclosed. A plurality of fibers are packed together in a casing so as to provide good flow characteristic... | 06/22/2010 |
| 7699987 | Stabilized formulation A stabilized pharmaceutical composition of anticancer drug and a solvent like Polyethoxylated castor oil (cremophor) also containing any other suitable solubilizer suitable for human administration like dehydrated alcohol, is disclosed. Compositions prepared using t... | 04/20/2010 |
| 7682510 | Method of sterilization The present invention relates to a method of sterilizing a chromatography column which is packed with a separation matrix, which method comprises passing a superheated aqueous liquid through the packing of the column to obtain at least one substantially sterile pack... | 03/23/2010 |
| 7678276 | Method of substance separation by supercritical fluid chromatography and vapor liquid separator for use therein A method comprising liquefying a gas to thereby obtain a liquefied gas; injecting a sample into a mobile phase containing a solvent and a supercritical fluid formed from the liquefied gas; passing this mobile phase through a column so that the mobile phase containin... | 03/16/2010 |
| 7674381 | Method for preparing L-iditol Method for preparing highly pure L-iditol, consisting in subjecting a mixture of L-iditol and of L-sorbose to a chromatographic treatment, in such a way as to obtain at least two fractions, one of which is highly enriched in L-iditol and the other of which is highly... | 03/09/2010 |
