...that Charles Goodyear performed some of his experiments on rubber while in debtor's prison? He was there so often he referred to it as his "hotel". Chronically in debt because of poor business sense and ill health, Goodyear depended on the generosity of friends and family. Even after he unlocked the secret to vulcanizing rubber, he was unable to improve his financial situation. When he died, his estate was $200,000 in debt.
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| Number | Title | Issue Date |
| 7350401 | Liquid feeding system This liquid feeding system has the first and second pumps each of which is provided with a plunger. Liquid sucked through each of the pump suction ports is discharged out of the discharging port through the first pump and/or second pump. Under the starting operation... | 04/01/2008 |
| 7351333 | Centrifuge A centrifuge (10) is provided with a cantilevered shaft (18) upon which the main drive rotor (26) is located. A bobbin (62) is attached to the planetary gear shaft (44), which is driven in planetary motion by the rotation of the ro... | 04/01/2008 |
| 7350427 | Sorbent collector material based on polyorganosiloxane The invention relates to a sorbent collector material based on polyorganosiloxane for the microextraction of substances to be analysed, the collector material having an open-cell foam structure, and to a collector and a liner which include this collector material. | 04/01/2008 |
| 7347976 | Methods and devices for removal of organic molecules from biological mixtures using a hydrophilic solid support in a hydrophobic matrix Methods and devices for removing small negatively charged molecules from a biological sample mixture that uses a solid-phase extraction material that includes a hydrophilic solid support at least partially embedded within a hydrophobic matrix. ... | 03/25/2008 |
| 7347943 | Methods and compositions for chromatography The present invention is directed to methods and compositions for separating and isolating target molecules. In particular, the present invention comprises devices, such as CCDs, that contain particles without the need for support structures. Chromatography separati... | 03/25/2008 |
| 7347936 | Liquid chromatograph A liquid chromatograph has switching valves as a flow passage switching mechanism and an automatic sampler as an injection section. The liquid chromatograph can switch, by switching the switching valves between a concentration flow passage for concentrating the samp... | 03/25/2008 |
| 7347880 | Flat capacitor having staked foils and edge-connected connection members A method of joining a connection member to a capacitor foil using a staking tool having a tip of less than 0.030″ (0.762 mm) in diameter. Another embodiment couples multiple connection members of a capacitor together by edge-connecting each connection member to it... | 03/25/2008 |
| 7348526 | Microwave-assisted chromatography preparation An instrument and associated method are disclosed for preparing samples for column chromatography. The method includes the steps of applying microwave energy to a sample composition containing at least one solvent to encourage a chemical reaction and generate desire... | 03/25/2008 |
| 7341662 | Distribution and collection headers for a filter bed A filtration vessel has an inlet for inflow into the filtration vessel of liquid media to be filtered, a body of filter media in the filtration vessel, and a drain to receive filtered liquid media for take off from the filtration vessel. The inlet is configured to i... | 03/11/2008 |
| 7338088 | Connector A connector is provided for selectively coupling one or more lines or wires (19′, 19″) to a receiving and/or transporting device (27). The connector comprises at least one line or wire receiving ferrule (7) having a plurality of line and/or ... | 03/04/2008 |
| 7338681 | Process to prepare a premium formulated fried egg The present invention relates to the formulation and process for preparation of a fried egg product which may be frozen for future heating within a microwave or other oven for consumption by an individual. Various ingredients are added and mixed to each of the liqui... | 03/04/2008 |
| 7335347 | Methods for purifying radiolabelled compounds One aspect of the present invention relates to a method of purifying radiolabelled compounds comprising a) loading onto a fluorous polymer a radiolabelled compound precursor comprising a fluoroalkyl tin moiety; b) reacting the radiolabelled compound precursor with a... | 02/26/2008 |
| 7335339 | Disposable apparatus for use in blood testing A disposable apparatus for use in blood testing and being adapted for simultaneous dilution of a blood sample into two different dilution ratios, said apparatus including a block-shaped housing having integrated therein a first and a second receptacle, one of which ... | 02/26/2008 |
| 7335306 | Chromatographic medium A chromatographic medium including thioether ligands bound to a cross-linked polymer matrix. The polymer is an organic polymer and the medium is hydrophilic. A method of manufacturing the media is also described. The media are useful in the chromatographic separatio... | 02/26/2008 |
| 7334630 | Closed-loop microchannel cooling system Apparatus and methods according to the present invention utilize micropumps that are capable of generating high pressure and flow without moving mechanical parts and the associated generation of unacceptable electrical and acoustic noise, as well as the associated r... | 02/26/2008 |
| 7332347 | Apparatus and method for concentrating and collecting analytes from a flowing liquid stream An apparatus for concentrating and collecting one or more analytes in a flowing liquid stream of a carrier solvent composed of one or more solvent components is provided, which includes a transfer tube which forms a bore having an inlet and an outlet, the inlet bein... | 02/19/2008 |
| 7332086 | Method for preparing a separation medium The present invention relates to a method of preparing a separation medium starting with an aqueous solution of spherical and preferably functionalised primary particles of defined size, comprising the following steps: a) inverse s... | 02/19/2008 |
| 7332126 | Integrated microfluidic disc Disclosed is a method for performing the steps of nucleic acid template purification, thermocycling reaction and purification of the products of the thermocycling reaction characterized in that the steps take place sequentially in a microfluidic disc. Also disclosed... | 02/19/2008 |
| 7332081 | Filter device for the clarification of contaminated liquids A filter device for the clarification of contaminated liquids includes a vessel configured to contain the liquid to be clarified. A first carrying disk is arranged within the vessel and is rotationally driven about a rotational axis. Mounting rods are attached to an... | 02/19/2008 |
| 7332087 | Flow sensing apparatus used to monitor/provide feedback to a split flow pumping system A method and apparatus for monitoring and controlling the nano-scale flow rate of fluid in the operating flow path of a HPLC system without relying on a nano-scale sensor in the operating flow path. A main flow sensor is disposed in the main flow path between the pu... | 02/19/2008 |
| 7329386 | Column packing material and method for producing the same The first subject of this invention is a column packing material comprising: a silica gel having a silanol group; a first chemical modification group which is bound to said silanol group; a silicon... | 02/12/2008 |
| 7329346 | Ion chromatography system using catalytic gas elimination A liquid chromatographic system is provided including catalytically combining hydrogen and oxygen gases in the chromatography eluent stream in a catalytic gas elimination chamber, to form water and thereby reduce the gas content in the eluent stream. Also, a liquid ... | 02/12/2008 |
| 7329353 | LC/MS method of analyzing high molecular weight proteins The present invention is directed to a novel method of analysis of high molecular weight proteins. More specifically, it is directed to a novel reversed-phase LC/MS method of analysis of high molecular weight proteins including antibodies. ... | 02/12/2008 |
| 7329484 | Retentate chromatography and protein chip arrays with applications in biology and medicine This invention provides methods of retentate chromatography for resolving analytes in a sample. The methods involve adsorbing the analytes to a substrate under a plurality of different selectivity conditions, and detecting the analytes retained on the substrate by d... | 02/12/2008 |
| 7326464 | Calcium phosphate microgranules The invention concerns microgranules produced from calcium phosphate materials. The invention also concerns a method for producing said microgranules. The inventive microgranules are characterized by a very narrow particle size distribution. ... | 02/05/2008 |
| 7326182 | Method of using device for bio-affinity material for treatment of blood or plasma Bio-affinity material containing at least one biologically active saccharide which is covalently bound via at least one spacer to a cross-linked matrix and that the material is autoclaved. Apparatus for contacting body fluids with the bio-affinity material is disclo... | 02/05/2008 |
| 7323101 | Separating agent for optical isomer and method for preparation thereof A separating agent which combines a high optical resolving power inherent in polysaccharide derivatives with sufficient solvent resistance and a method with which the separating agent can be produced efficiently in short steps. The separating agent for enantiomeric ... | 01/29/2008 |
| 7320754 | Method of preparing multi-modal anion-exchange ligands The invention relates to a method of preparing multi-modal anion-exchange ligands, which comprises providing a cyclic three-functional scaffold comprising an amine, a carbonyl and a thiol; optionally derivatisation of the amine of the scaffold to provide an anion-ex... | 01/22/2008 |
| 7320755 | Method of preparing ligands for hydrophobic interaction chromatography The invention is a method of preparing multimodal ligands for hydrophobic interaction chromatography (HIC), which comprises providing a cyclic scaffold comprising a thiol, an amine and a carbonyl group; derivatisation of the nitrogen with a reagent to introduce a pr... | 01/22/2008 |
| 7318900 | Chromatography system and method A chromatography system and method for analyzing a sample of interest. The chromatography system can include a housing, a cartridge holder coupled to the housing and formed to hold a chromatography cartridge containing a stationary phase, a collection vessel stand h... | 01/15/2008 |
| 7317187 | Frontal affinity chromatography/MALDI tandem mass spectrometry Sol-gel derived monolithic silica columns containing entrapped dihydrofolate reductase were used for frontal affinity chromatography of small molecule mixtures. The output from the column combined with a second stream containing the matrix molecule (HCCA) and was di... | 01/08/2008 |
| 7316730 | Inlet double-seal assembly An inlet seal assembly for sealing an injection port member in a chromatography instrument , comprising an injection port member having a raised metal ring, an inlet seal member with an upper surface, a peripheral groove formed in the inlet seal member upper surface... | 01/08/2008 |
| 7316777 | Compression fitting nut with interlocked ferrule The invention pertains to a nut and ferrule assembly for use in joining tubing to a fitting. The ferrule has a male member which interlocks with a nut and freely rotates within the nut. The interlock reduces the number of parts necessary to be handled, eliminates th... | 01/08/2008 |
| 7316902 | Compositions that specifically bind to colorectal cancer cells and methods of using the same A unique transcription product, CRCA-1, and alternative translation products generated therefrom, are disclosed. The transcript and its translation products are markers for colorectal cells. Screening and diagnostic reagents, kits and methods for metastasized colore... | 01/08/2008 |
| 7316919 | Composite materials comprising supported porous gels This invention relates to a composite material that comprises a support member that has a plurality of pores extending through the support member and, located in the pores of the support member, and filling the pores of the support member, a macroporous cross-linked... | 01/08/2008 |
| 7314505 | Stationary phase deposition based on onium salts Onium salt chemistry can be used to deposit very uniform thickness stationary phases on the wall of a gas chromatography column. In particular, the stationary phase can be bonded to non-silicon based columns, especially microfabricated metal columns. Non-silicon mic... | 01/01/2008 |
| 7314070 | Method and apparatus for gradient generation A method and apparatus for treating a fluid. A method for treating a fluid may include combining two or more separate streams into a common stream and then splitting the common stream into a new set of separate streams wherein the separate streams may possess differ... | 01/01/2008 |
| 7314550 | Analytical separations with polyelectrolyte layers, molecular micelles, or zwitterionic polymers Polymeric surfactants (molecular micelles) are disclosed for use in open tubular capillary electrochromatography or in high performance liquid chromatography. For example, fused silica capillaries are coated with thin films of charged polymers in a polyelectrolyte m... | 01/01/2008 |
| 7314567 | Method for transferring heterogeneous liquids in microchannels without the occurrence of mixing In the method for mixing-free transport of homogeneous liquids in microchannels a heterogeneous liquid flow (14) is autonomously divided into portions, transported over a distance and then autonomously recombined. When the flow is divided into portions, indiv... | 01/01/2008 |
| 7314845 | Supported catalyst systems The present invention relates to a supported catalyst system. The supported catalyst of the present invention comprises an inorganic support having attached to at least one surface thereof non-acidic, hydrophilic, hydroxyl-containing organic R10 groups ha... | 01/01/2008 |