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| Number | Title | Issue Date |
| 7678269 | Asymmetric porous adsorptive bead The present invention relates to an asymmetric chromatography media suitable for separations applications, particularly as packed bed, fluidized bed or magnetized bed chromatography media. In certain embodiments, the asymmetric chromatography media comprises asymmet... | 03/16/2010 |
| 7674375 | Closed loop flow control of a HPLC constant flow pump to enable low-flow operation A method and apparatus for monitoring and controlling nano-scale flow rate of fluid in the operating flow path of a HPLC system provide fluid flow without relying on complex calibration routines to compensate for solvent compositions gradients typically used in HPLC... | 03/09/2010 |
| 7670487 | De-pressurization scheme for chromatography columns A depressurization process for a packed separation column is provided where the column system experiences a rapid and/or severe drop in pressure that could potentially damage column components. The process provides a safe de-pressurization of the column on the outle... | 03/02/2010 |
| 7635425 | Integrated high throughput system for the analysis of biomolecules Described is an affinity microcolumn comprising a high surface area material, which has high flow properties and a low dead volume, contained within a housing and having affinity reagents bound to the surface of the high surface area material that are either activat... | 12/22/2009 |
| 7632404 | Barrier with a seated ion exchange bead and method Ion transport apparatus (e.g. an electrolytic eluent generator or a suppressor for ion chromatography) in which ions in a first chamber are transported to a liquid in second chamber through a wall comprising an ion exchange bead sealed in a bead seat. The wall is ca... | 12/15/2009 |
| 7628915 | Metal cyano bonded phases A composition for use in chromatography is provided comprising a substrate modified with a metal-cyano bonded phase. This novel cyano bonded phase provides superior performance in high performance liquid chromatography (HPLC) and provides superior selectivity, impro... | 12/08/2009 |
| 7628914 | Methods for time-alignment of liquid chromatography-mass spectrometry data Nonlinear retention time variations in chromatography-mass spectrometry data sets are adjusted by time-alignment methods, enabling automated comparison of spectra for differential phenotyping and other applications. ... | 12/08/2009 |
| 7618535 | Suppressed chromatography and salt conversion system Method and apparatus for suppressed ion analysis in which a sample solution of analyte (e.g., anion) in an eluent of electrolyte counterions (e.g., sodium), is chromatographically separated. Then, the counterions are suppressed in a suppression zone and removed and ... | 11/17/2009 |
| 7615150 | Separation agent for separating optical isomer and method for preparation thereof A method of producing a novel separating agent for separating enantiomeric isomers, characterized by including: a step of supporting an optically active polymer compound and a compound having an asymmetric structure of a molecular weight of 1,000 or less on a carrie... | 11/10/2009 |
| 7604736 | Laser welded frit A method of forming a column (100 and 200) for use with an analytical chemical instrument. The method includes placing a frit (102 and 202) in proximity to a distal end (110 and 210) of a tube (104 and 204) hav... | 10/20/2009 |
| 7597804 | Optically active support materials, their method of preparation and their uses This invention relates to optically active support materials which include one or more esters and/or one or more carbamates and/or one or more mixed ester and carbamate compounds of polysaccharide or oligosaccharide, and an organic and/or inorganic substrate. ... | 10/06/2009 |
| 7594999 | Multi column chromatography system The present invention relates to a method and apparatus for chromatographically analyzing each of a plurality of samples in detector, comprising an autosampler to contain a plurality of samples for chromatographic analysis and a plurality of chromatographic systems,... | 09/29/2009 |
| 7588683 | Column for liquid chromatography with adjustable compression A column for liquid chromatography includes a chamber adapted to receive packing medium. Openings in the chamber allow fluid to pass through it. Porous plugs in the chamber retain the packing medium. A piston and one porous plug are movable within the chamber to com... | 09/15/2009 |
| 7582207 | Process and device for simulated moving bed separation with a reduced number of large diameter valves The invention concerns a simulated moving bed (SMB) separation device and process comprising a column, beds Ai of adsorbent separated by plates Pi with a single distribution and extraction network for fluids, in particular feed F, desorbant D, ... | 09/01/2009 |
| 7582208 | Process and device for simulated moving bed separation with a reduced number of valves and lines The invention concerns a simulated moving bed adsorption separation device comprising a limited number of valves. According to the invention, the device comprises a column with a plurality of sectors Sk with 2 superimposed plates Pi with a single distribution networ... | 09/01/2009 |
| 7582206 | Process and device for simulated moving bed separation with a reduced number of valves A simulated moving bed (SMB) separation device comprising a column, beds Ai of adsorbent separated by plates Pi with a single distribution and extraction network for fluids, in particular feed F, desorbant D, raffinate R and extract B, and a plurality of two-way val... | 09/01/2009 |
| 7578934 | Chromatographic column seal A seal on a movable top or bottom plate for use in a chromatography column. The plate is formed of a flow distributor connected to one or more movement rods that control the movement of the top plate within a chromatography column. The plate is formed of two pieces,... | 08/25/2009 |
| 7575676 | HPLC column holder apparatus An HPLC column holding apparatus used to mount an HPLC column in one of a plurality of positions is disclosed herein. The apparatus comprises a clip-device interface that secures the apparatus to a platform and a clip-column interface that secures the HPLC column to... | 08/18/2009 |
| 7569141 | Process and device for simulated moving bed separation with a reduced number of large diameter valves and a reduced line volume The invention concerns a simulated moving bed adsorption separation device comprising a limited number of large diameter valves. According to the invention, the device comprises a column with a plurality of sectors Sk with 2 superimposed plates Pi with a single dist... | 08/04/2009 |
| 7566395 | Purification system The present invention relates to automated chromatography systems and software for controlling such automated systems for optimising the purification of a protein from a sample. The software is adapted to monitor the signal from a detector in the system, determine t... | 07/28/2009 |
| 7566396 | Flow path switching valve and high performance liquid chromatograph using the same The present invention is directed to reduce the dead volume in a flow path with trap functions. A flow path switching valve 1 is provided, which includes a rotor, i.e., rotor 3, and a housing top 9 having four ports 7a-7d... | 07/28/2009 |
| 7563367 | pH stable chromatographic media using templated multilayer organic/inorganic grafting An advanced silica gel sorbent for use in chromatographic separations that has been chemically modified by surface polycondensation of a trifunctional and/or difunctional organosilane. The chromatographic media exhibits a wider pH range and improved pH stability as ... | 07/21/2009 |
| 7560023 | Method of modifying surface of material A method for surface modification of a material by means of introducing the phosphorylcholine group represented by the following formula (1-1) onto the surface of the material by treating a material having amino groups with a chemical compound containing an aldehyde... | 07/14/2009 |
| 7556731 | Liquid chromatograph A liquid chromatograph having a flow passage switching mechanism for switching among a normal analysis flow passage formed by connecting a mobile-phase-sending-unit, a second mixer having a large capacity, a sample injection portion, an analysis column and a detecto... | 07/07/2009 |
| 7550080 | Liquid chromatograph analysis apparatus and method A liquid chromatograph analysis apparatus includes: a macro storing section for storing a macro program having various commands related to a purge operation; a macro executing section for reading the macro program and analyzing and executing the program thus read; a... | 06/23/2009 |
| 7550081 | Mobile phase supplying apparatus, liquid chromatograph using the same, and mobile phase supplying method In liquid-feeding sections for feeding two types of mobile phases A, B, respectively, actual flow rate measuring sections capable of detecting back-flows are provided in downstream of liquid-feeding pumps, respectively. Control devices control driving of the liquid ... | 06/23/2009 |
| 7544293 | Valve and process for interrupted continuous flow chromatography A unique valve assembly for simulated bed moving chromatography employs a combination of pressure compatible sealable materials that permit minimal frictional interaction between moving parts, ensures alignment of parts, and provides a method for conducting SMB coun... | 06/09/2009 |
| 7537694 | Method and device for multidimensional liquid chromatography In a liquid chromatography, an electrolytic solution starts to be supplied from an injector toward a specimen in a first separating column to transfer components of the specimen from the first separating column toward one of first and second trap columns after a tim... | 05/26/2009 |
| 7534345 | Chromatography column distribution system A chromatography column distribution system (101) comprises a set of first bed support ribs (107) extending radially from a inner, first radial position (R1) near the centre of the plate to a outer radial position nearer to the periphery (109... | 05/19/2009 |
| 7534346 | Chromatography columns The present invention relates to a chromatography column that removes the longitudinal load from the column tube altogether and transfers it to a yoke and stanchion arrangement situated around but external to the column tube. By using the yoke/stanchion system, the ... | 05/19/2009 |
| 7520982 | Cucurbituril-containing polymer, stationary phase and column using the same Provided is a cucurbituril-containing polymer. The cucurbituril-containing polymer may be used in removal, separation, or purification of air pollutants, water contaminants, biological substances, organic or inorganic substances, alkaline metals, heavy metals, ionic... | 04/21/2009 |
| 7507336 | Connector for analytical devices A connector element for use with analytical devices is provided. The connector element includes a cavity for receiving a sealing member, and an access element for providing access to the sealing member when disposed in the cavity, e.g., for dislodging the sealing me... | 03/24/2009 |
| 7507337 | System and method for rapid chromatography with fluid temperature and mobile phase composition control The invention relates to liquid chromatography techniques for rapidly characterizing samples, such as polymer solutions, emulsions and dispersions, and to devices for implementing such techniques. The system includes a design that provides the ability to perform chr... | 03/24/2009 |
| 7504029 | Silica gel bonded with cucurbituril A cucurbituril-bonded silica gel and its use are provided. The cucurbituril-bonded silica gel is useful for removal of air pollutants or water contaminants, and separation and purification of biological, organic, inorganic, or ionic substances. ... | 03/17/2009 |
| 7491326 | Apparatus for distributing liquids having an adapter An apparatus for distributing liquids to one or more receiving elements. The apparatus comprises a first element arrangement having one or more first receiving elements, a second element arrangement having one or more second receiving elements, a distributor adapted... | 02/17/2009 |
| 7488420 | Chromatographic separator A chromatographic separator characterized in that two pumps are employed for controlling chromatographic separation that combines a first process for supplying at least one of feed solution and eluent into a circulation system and extracting the same quantity as tha... | 02/10/2009 |
| 7479222 | Porous adsorptive or chromatographic media A porous substrate capable of adsorptive filtration of a fluid having a porous self-supporting substrate and one or more porous, adsorptive polymeric coatings comprising from about 1 to about 80% of the void volume of the pores of the substrate. The resultant substr... | 01/20/2009 |
| 7479223 | Porous adsorptive or chromatographic media A porous substrate capable of adsorptive filtration of a fluid having a porous self-supporting substrate and one or more porous, adsorptive coatings comprising from about 1 to about 80% of the void volume of the pores of the substrate. The resultant substrate has go... | 01/20/2009 |
| 7473354 | Recycled suppressor regenerants A suppressed ion chromatographic apparatus using a regenerant recycle loop, comprising (a) an ion separation device, (b) a membrane suppressor, (c) a detector, (d) a container for regenerant solution, (e) a first conduit between the ion separation device and the sup... | 01/06/2009 |
| 7468130 | Organosilanes and substrates covalently bonded with same and methods for synthesis and use same The present invention provides novel silicon compounds, methods for making these novel silicon compounds, compositions comprising these novel silicon compounds attached to substrates, methods for attaching the novel silicon compounds to substrates and methods for us... | 12/23/2008 |