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Class 210/198.2 - Chromatography


Subclass of Class 210 - Liquid purification or separation
Definition: Apparatus for carrying out the process of chromatography.
No. of patents: 2308
Last issue date: 01/24/2012


1                      
NumberTitleIssue Date
8101073Separating agent for solid-phase extraction
The present invention relates to a separating agent for solid-phase extraction which comprises core particles of a base material; a hydrophilic polymer layer formed on the surface of the particles; and a hydrophobic polymer layer formed on the surface of the hydroph...
01/24/2012
8092677Separating agent for an enantiomeric isomer
The present invention is to provide a method of producing a separating agent for an enantiomeric isomer having a high optical resolution power together with sufficient solvent resistance. That is, a method of producing a separating agent for an enantiomeric isomer c...
01/10/2012
8075768Liquid chromatograph device
A liquid chromatograph device was provided wherein operations inside a thermostatic chamber can be safely performed even while a heat block is being heated. The liquid chromatograph device comprises: a thermostatic chamber; outer doors and that are disposed at the f...
12/13/2011
8075767Integrated high throughput system for the analysis of biomolecules
Described is an affinity microcolumn comprising a high surface area material, which has high flow properties and a low dead volume, contained within a housing and having affinity reagents bound to the surface of the high surface area material that are either activat...
12/13/2011
8066876Apparatus and methods for packing chromatography columns
A chromatographic apparatus may include a hydraulic lifting mechanism axially movable from a lowered position to a raised position such that a column and flange of the apparatus are axially movable with the hydraulic lifting mechanism. In a packing system, a mobile ...
11/29/2011
8066875Flash chromatography cartridge
A low pressure liquid chromatographic cartridge is provided having a tubular polymer container adapted to receive a chromatographic packing material. The container has an outlet port located at a downstream end of the container and container threads formed on an ups...
11/29/2011
8062516Low thermal mass, adjustable locking GC nut
A connector for fastening a gas chromatography capillary column to chromatography equipment includes a securing nut and ferrule on a first portion of the connector for releasably holding the capillary column in a position relative to a second portion of the connecto...
11/22/2011
8062515Parking a sample stream and suppressing the sample
Pretreatment method and apparatus to remove matrix ions from a liquid sample, prior to separation of the sample analytes (e.g. by chromatography), by flowing the liquid sample into a sample compartment and stopping the flow. The sample compartment has a wall compris...
11/22/2011
8057668Method and device for extracting an analyte
The invention provides extraction columns for the purification of an analyte (e.g., a biological macromolecule, such as a peptide, protein or nucleic acid) from a sample solution, as well as methods for making and using such columns. The columns typically include a ...
11/15/2011
8034239Device for sample preparation
This invention relates to a pipette tip or tube designed to perform biological or chemical sample preparation, purification or separation. The narrow end of the pipette tip is twisted in such a way that it forms a narrow spiral passage, which allows the retention of...
10/11/2011
7981284Suppressor utilizing micro ion exchange tube and ion chromatograph utilizing the same
Disclosed herein is a suppressor using one ion-exchange tube which has an inner diameter close to that of a tube connected to a separation column and which is constituted by an ion-exchange membrane. The ion-exchange tube is folded or wound more than once in a plane...
07/19/2011
7972506Chromatography columns and their operation
A chromatography column (100) is disclosed comprising a housing (10) comprising a tubular side wall (1); opposed, axially spaced end units (2,3) which together with the side wall define an enclosed bed space to contain a bed of particulat...
07/05/2011
7964097Multicapillary column for chromatography and sample preparation
A multicapillary column especially useful for liquid chromatography and sample preparation comprising a plurality of uniform capillaries coated with an insoluble stationary phase, wherein the thickness of the stationary phase is correlated with the radius of the ind...
06/21/2011
7959801Device for generating micro- and nanoflow mobile phase gradients for high-performance liquid chromatography
A device for generating micro- and nanoflow mobile phase gradients for high performance liquid chromatography includes a generator of micro- and nanoflows of at least two mobile phases in different percentage compositions; an n-position gradient distributor having i...
06/14/2011
7947175Continuous countercurrent tangential chromatography (CCTC)
The present invention is a system for continuous, single-pass countercurrent tangential chromatography having multiple single-pass modules. A single-pass binding step module is used for binding product from an unpurified product solution with a resin slurry. A singl...
05/24/2011
7947174Sol-gel monolithic column with optical window and method of making
A method of preparing a sol-gel monolithic column includes the step of forming a separation bed (14) from a sol-gel solution in a single process step. This column has improved characteristics for CEC based on its incorporated surface charge and ease of operat...
05/24/2011
7938961Capillary loop with a built-in retaining frit
Disclosed herein are an apparatus and method for effectuating increased chromatographic efficiency in a capillary column by employing a retaining frit disposed within an analytical capillary. By disposing the retaining frit within the analytic capillary, the void vo...
05/10/2011
7938962Separating agent for enantiomeric isomers and method of producing the same
A separating agent which combines a high optical resolving power inherent in polysaccharide derivatives with sufficient solvent resistance and a method with which the separating agent can be produced efficiently in short steps. The separating agent for enantiomeric ...
05/10/2011
7927486Polymer modified porous substrate for solid phase extraction
A polymer modified porous substrate for solid phase extraction or chromatography, comprising a porous substrate and a polymeric monolith formed thereon, wherein the polymeric monolith comprises C5-10 monocyclic or bicyclic aryl or heteroaryl, optionally s...
04/19/2011
7927487Chromatographic column system
Chromatographic column system, in particular a chromatographic column system of the expanded bed adsorption column type comprises a column connected to a fluid inlet and a fluid outlet and dimensioned to comprise an expandable filter bed between said fluid inlet and...
04/19/2011
7914673Fluid distribution apparatus
Disclosed is a mixer-distributor-collector apparatus for use between beds of solid particles in a fluid-solid contacting vessel. The apparatus includes a solids retaining screen, fluid deflector, passageway, fluid distributor, and flow manipulator. The flow manipula...
03/29/2011
7909993Centrifugal fraction collection system and method
A centrifugal fraction collection system including a rotating carrier for holding at least one sample collection container and inducing a centrifugal force, a guide disposed on the rotating carrier, and a flexible eluant tube disposed over the rotating carrier and t...
03/22/2011
7909994Mobile phase dilution scheme for enhanced chromatography
A method and device for increasing the loading capacity of a chromatography column through dilution of a mobile phase at the head of the column. A strong mobile phase is provided for dissolving a sample. A sample is injected into the strong mobile phase, and subsequ...
03/22/2011
7901573Separation column and liquid chromatography apparatus using the same
Disclosed herein is a separation column comprising a porous block covered with a coating wherein space-free adhesion is attainable therebetween by low temperature process without releasing octadecylsilyl bases and others from the porous block. A monolith rod 1
03/08/2011
7901574Quick disconnect liquid chromatograph columns
A chromatography column comprising a chromatography tube, a piston tube with a porous obstruction that inhibits the movement of particle solids therethrough, and a quick connect/disconnect clamp for use in coupling the chromatography tube to the piston tube. This co...
03/08/2011
7897044Fluid separation device
The present invention relates to a fluidic separation device comprising: at least one microchannel (2; 66) extending along a longitudinal axis (X), the microchannel having a cross-section that presents a width measured along...
03/01/2011
7875175Mobile phase dilution scheme for enhanced chromatography
A method and device for increasing the loading capacity of a chromatography column through dilution of a mobile phase at the head of the column. A strong mobile phase is provided for dissolving a sample. A sample is injected into the strong mobile phase, and subsequ...
01/25/2011
7867391Cucurbituril derivative-bonded solid substrate and biochip using the same
The present disclosure provides a cucurbituril derivative-bonded solid substrate in which cucurbituril derivatives of Formula 1 are covalently bonded to a modified solid substrate of Formula 2. The cucurbituril derivative provides functional groups which can be used...
01/11/2011
7862716HPLC schematic with integrated sample cleaning system
The disclosed HPLC flow schematic back-flushes the guard column with mobile phase once every operating cycle, the regular cleaning maintaining its effectiveness and useful life. This mobile phase flow reversal is accomplished by imposing a two position multiple port...
01/04/2011
7850844Liquid delivery device, liquid chromatograph, and method for operation of liquid delivery device
The present invention provides a liquid delivery device for liquid chromatographs which, by performing liquid delivery at an accurate flow rate with limited pulsation, gives accurate results of analyses. The present invention, with a view to preventing erroneous ope...
12/14/2010
7837871Method and device for extracting an analyte
The invention provides extraction columns for the purification of an analyte (e.g., a biological macromolecule, such as a peptide, protein or nucleic acid) from a sample solution, as well as methods for making and using such columns. The columns typically include a ...
11/23/2010
7824548Porous adsorptive or chromatographic media
A porous substrate capable of adsorptive filtration of a fluid having a porous self-supporting substrate and one or more porous, adsorptive polymeric coatings comprising from about 1 to about 80% of the void volume of the pores of the substrate. The resultant substr...
11/02/2010
7820042Method for removing air from a chromatography column
The invention relates to a method for removing air from the bed space of a chromatography column. The method involves use a chromatography column having an inner wall which comprises at least one elongated groove through which air can pass from the bed space to a ch...
10/26/2010
7815799Continuous countercurrent chromatography system
A continuous countercurrent chromatography system has several rotating chambers arranged around a rotational axis. The chambers are provided for receiving a liquid or liquid mixture to be examined, and the individual chambers are interconnected via liquid carrying c...
10/19/2010
7815798Discrete drop dispensing device and method of use
A discrete drop dispensing device comprises a substrate comprising an upper surface and a lower surface and orifices extending from the upper surface to the lower surface, adapted to receive a fluid at a flow rate. The discrete drop dispensing device also comprises ...
10/19/2010
7811453Hydrophilic polymer microparticle, filler for ion exchange liquid chromatography, and method for production of filler for ion exchange liquid chromatography
An object of the present invention is to provide a hydrophilic polymer microparticle which shows reduced swelling in an aqueous medium and has an excellent dispersibility in an aqueous medium, a filler for ion-exchange liquid chromatography which can effectively sup...
10/12/2010
7811452Microfluidic device for sample analysis
A device for sample analysis includes a microfluidic device for separating analytes of a sample comprising a liquid, the microfluidic device comprising a substrate having a first surface and a second surface opposite the first surface, the substrate defining feature...
10/12/2010
7811451Separation column and liquid chromatograph using the same
The flow rate of a solvent is reduced as a separation column and the separation performance is improved even under high-pressure conditions. There is provided a separation column including a monolith rod into which a sample and a mobile phase flow, the separation co...
10/12/2010
7807054Chromatography columns
The present invention relates to a chromatography column that removes the longitudinal load from the column tube altogether and transfers it to a yoke and stanchion arrangement situated around but external to the column tube. By using the yoke/stanchion system, the ...
10/05/2010
7790025External gradient chromatofocusing
The invention provides novel methods for the separation of charged molecules such as proteins according to the isoelectric points (pI's) and includes the systems and buffering compositions employed for isolating charged molecules. The invention further provides for ...
09/07/2010
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