...that several people are credited with the invention of the flush toilet? Most people have heard of Thomas Crapper (1837-1910), the sanitary engineer who invented the valve-and-siphon arrangement that made the modern toilet possible. Another claimant to "the throne" was British inventor Alexander Cumming who patented a toilet in 1775. Then there's a nameless Minoan (a native of ancient Crete) who lived 4,000 years ago who supposedly was ahead of his time and created the first flush toilet!
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| Number | Title | Issue Date |
| 8101073 | Separating agent for solid-phase extraction The present invention relates to a separating agent for solid-phase extraction which comprises core particles of a base material; a hydrophilic polymer layer formed on the surface of the particles; and a hydrophobic polymer layer formed on the surface of the hydroph... | 01/24/2012 |
| 8092677 | Separating agent for an enantiomeric isomer The present invention is to provide a method of producing a separating agent for an enantiomeric isomer having a high optical resolution power together with sufficient solvent resistance. That is, a method of producing a separating agent for an enantiomeric isomer c... | 01/10/2012 |
| 8075768 | Liquid chromatograph device A liquid chromatograph device was provided wherein operations inside a thermostatic chamber can be safely performed even while a heat block is being heated. The liquid chromatograph device comprises: a thermostatic chamber; outer doors and that are disposed at the f... | 12/13/2011 |
| 8075767 | Integrated high throughput system for the analysis of biomolecules Described is an affinity microcolumn comprising a high surface area material, which has high flow properties and a low dead volume, contained within a housing and having affinity reagents bound to the surface of the high surface area material that are either activat... | 12/13/2011 |
| 8066876 | Apparatus and methods for packing chromatography columns A chromatographic apparatus may include a hydraulic lifting mechanism axially movable from a lowered position to a raised position such that a column and flange of the apparatus are axially movable with the hydraulic lifting mechanism. In a packing system, a mobile ... | 11/29/2011 |
| 8066875 | Flash chromatography cartridge A low pressure liquid chromatographic cartridge is provided having a tubular polymer container adapted to receive a chromatographic packing material. The container has an outlet port located at a downstream end of the container and container threads formed on an ups... | 11/29/2011 |
| 8062516 | Low thermal mass, adjustable locking GC nut A connector for fastening a gas chromatography capillary column to chromatography equipment includes a securing nut and ferrule on a first portion of the connector for releasably holding the capillary column in a position relative to a second portion of the connecto... | 11/22/2011 |
| 8062515 | Parking a sample stream and suppressing the sample Pretreatment method and apparatus to remove matrix ions from a liquid sample, prior to separation of the sample analytes (e.g. by chromatography), by flowing the liquid sample into a sample compartment and stopping the flow. The sample compartment has a wall compris... | 11/22/2011 |
| 8057668 | Method and device for extracting an analyte The invention provides extraction columns for the purification of an analyte (e.g., a biological macromolecule, such as a peptide, protein or nucleic acid) from a sample solution, as well as methods for making and using such columns. The columns typically include a ... | 11/15/2011 |
| 8034239 | Device for sample preparation This invention relates to a pipette tip or tube designed to perform biological or chemical sample preparation, purification or separation. The narrow end of the pipette tip is twisted in such a way that it forms a narrow spiral passage, which allows the retention of... | 10/11/2011 |
| 7981284 | Suppressor utilizing micro ion exchange tube and ion chromatograph utilizing the same Disclosed herein is a suppressor using one ion-exchange tube which has an inner diameter close to that of a tube connected to a separation column and which is constituted by an ion-exchange membrane. The ion-exchange tube is folded or wound more than once in a plane... | 07/19/2011 |
| 7972506 | Chromatography columns and their operation A chromatography column (100) is disclosed comprising a housing (10) comprising a tubular side wall (1); opposed, axially spaced end units (2,3) which together with the side wall define an enclosed bed space to contain a bed of particulat... | 07/05/2011 |
| 7964097 | Multicapillary column for chromatography and sample preparation A multicapillary column especially useful for liquid chromatography and sample preparation comprising a plurality of uniform capillaries coated with an insoluble stationary phase, wherein the thickness of the stationary phase is correlated with the radius of the ind... | 06/21/2011 |
| 7959801 | Device for generating micro- and nanoflow mobile phase gradients for high-performance liquid chromatography A device for generating micro- and nanoflow mobile phase gradients for high performance liquid chromatography includes a generator of micro- and nanoflows of at least two mobile phases in different percentage compositions; an n-position gradient distributor having i... | 06/14/2011 |
| 7947175 | Continuous countercurrent tangential chromatography (CCTC) The present invention is a system for continuous, single-pass countercurrent tangential chromatography having multiple single-pass modules. A single-pass binding step module is used for binding product from an unpurified product solution with a resin slurry. A singl... | 05/24/2011 |
| 7947174 | Sol-gel monolithic column with optical window and method of making A method of preparing a sol-gel monolithic column includes the step of forming a separation bed (14) from a sol-gel solution in a single process step. This column has improved characteristics for CEC based on its incorporated surface charge and ease of operat... | 05/24/2011 |
| 7938961 | Capillary loop with a built-in retaining frit Disclosed herein are an apparatus and method for effectuating increased chromatographic efficiency in a capillary column by employing a retaining frit disposed within an analytical capillary. By disposing the retaining frit within the analytic capillary, the void vo... | 05/10/2011 |
| 7938962 | Separating agent for enantiomeric isomers and method of producing the same A separating agent which combines a high optical resolving power inherent in polysaccharide derivatives with sufficient solvent resistance and a method with which the separating agent can be produced efficiently in short steps. The separating agent for enantiomeric ... | 05/10/2011 |
| 7927486 | Polymer modified porous substrate for solid phase extraction A polymer modified porous substrate for solid phase extraction or chromatography, comprising a porous substrate and a polymeric monolith formed thereon, wherein the polymeric monolith comprises C5-10 monocyclic or bicyclic aryl or heteroaryl, optionally s... | 04/19/2011 |
| 7927487 | Chromatographic column system Chromatographic column system, in particular a chromatographic column system of the expanded bed adsorption column type comprises a column connected to a fluid inlet and a fluid outlet and dimensioned to comprise an expandable filter bed between said fluid inlet and... | 04/19/2011 |
| 7914673 | Fluid distribution apparatus Disclosed is a mixer-distributor-collector apparatus for use between beds of solid particles in a fluid-solid contacting vessel. The apparatus includes a solids retaining screen, fluid deflector, passageway, fluid distributor, and flow manipulator. The flow manipula... | 03/29/2011 |
| 7909993 | Centrifugal fraction collection system and method A centrifugal fraction collection system including a rotating carrier for holding at least one sample collection container and inducing a centrifugal force, a guide disposed on the rotating carrier, and a flexible eluant tube disposed over the rotating carrier and t... | 03/22/2011 |
| 7909994 | Mobile phase dilution scheme for enhanced chromatography A method and device for increasing the loading capacity of a chromatography column through dilution of a mobile phase at the head of the column. A strong mobile phase is provided for dissolving a sample. A sample is injected into the strong mobile phase, and subsequ... | 03/22/2011 |
| 7901573 | Separation column and liquid chromatography apparatus using the same Disclosed herein is a separation column comprising a porous block covered with a coating wherein space-free adhesion is attainable therebetween by low temperature process without releasing octadecylsilyl bases and others from the porous block. A monolith rod 1 | 03/08/2011 |
| 7901574 | Quick disconnect liquid chromatograph columns A chromatography column comprising a chromatography tube, a piston tube with a porous obstruction that inhibits the movement of particle solids therethrough, and a quick connect/disconnect clamp for use in coupling the chromatography tube to the piston tube. This co... | 03/08/2011 |
| 7897044 | Fluid separation device The present invention relates to a fluidic separation device comprising: at least one microchannel (2; 66) extending along a longitudinal axis (X), the microchannel having a cross-section that presents a width measured along... | 03/01/2011 |
| 7875175 | Mobile phase dilution scheme for enhanced chromatography A method and device for increasing the loading capacity of a chromatography column through dilution of a mobile phase at the head of the column. A strong mobile phase is provided for dissolving a sample. A sample is injected into the strong mobile phase, and subsequ... | 01/25/2011 |
| 7867391 | Cucurbituril derivative-bonded solid substrate and biochip using the same The present disclosure provides a cucurbituril derivative-bonded solid substrate in which cucurbituril derivatives of Formula 1 are covalently bonded to a modified solid substrate of Formula 2. The cucurbituril derivative provides functional groups which can be used... | 01/11/2011 |
| 7862716 | HPLC schematic with integrated sample cleaning system The disclosed HPLC flow schematic back-flushes the guard column with mobile phase once every operating cycle, the regular cleaning maintaining its effectiveness and useful life. This mobile phase flow reversal is accomplished by imposing a two position multiple port... | 01/04/2011 |
| 7850844 | Liquid delivery device, liquid chromatograph, and method for operation of liquid delivery device The present invention provides a liquid delivery device for liquid chromatographs which, by performing liquid delivery at an accurate flow rate with limited pulsation, gives accurate results of analyses. The present invention, with a view to preventing erroneous ope... | 12/14/2010 |
| 7837871 | Method and device for extracting an analyte The invention provides extraction columns for the purification of an analyte (e.g., a biological macromolecule, such as a peptide, protein or nucleic acid) from a sample solution, as well as methods for making and using such columns. The columns typically include a ... | 11/23/2010 |
| 7824548 | Porous adsorptive or chromatographic media A porous substrate capable of adsorptive filtration of a fluid having a porous self-supporting substrate and one or more porous, adsorptive polymeric coatings comprising from about 1 to about 80% of the void volume of the pores of the substrate. The resultant substr... | 11/02/2010 |
| 7820042 | Method for removing air from a chromatography column The invention relates to a method for removing air from the bed space of a chromatography column. The method involves use a chromatography column having an inner wall which comprises at least one elongated groove through which air can pass from the bed space to a ch... | 10/26/2010 |
| 7815799 | Continuous countercurrent chromatography system A continuous countercurrent chromatography system has several rotating chambers arranged around a rotational axis. The chambers are provided for receiving a liquid or liquid mixture to be examined, and the individual chambers are interconnected via liquid carrying c... | 10/19/2010 |
| 7815798 | Discrete drop dispensing device and method of use A discrete drop dispensing device comprises a substrate comprising an upper surface and a lower surface and orifices extending from the upper surface to the lower surface, adapted to receive a fluid at a flow rate. The discrete drop dispensing device also comprises ... | 10/19/2010 |
| 7811453 | Hydrophilic polymer microparticle, filler for ion exchange liquid chromatography, and method for production of filler for ion exchange liquid chromatography An object of the present invention is to provide a hydrophilic polymer microparticle which shows reduced swelling in an aqueous medium and has an excellent dispersibility in an aqueous medium, a filler for ion-exchange liquid chromatography which can effectively sup... | 10/12/2010 |
| 7811452 | Microfluidic device for sample analysis A device for sample analysis includes a microfluidic device for separating analytes of a sample comprising a liquid, the microfluidic device comprising a substrate having a first surface and a second surface opposite the first surface, the substrate defining feature... | 10/12/2010 |
| 7811451 | Separation column and liquid chromatograph using the same The flow rate of a solvent is reduced as a separation column and the separation performance is improved even under high-pressure conditions. There is provided a separation column including a monolith rod into which a sample and a mobile phase flow, the separation co... | 10/12/2010 |
| 7807054 | Chromatography columns The present invention relates to a chromatography column that removes the longitudinal load from the column tube altogether and transfers it to a yoke and stanchion arrangement situated around but external to the column tube. By using the yoke/stanchion system, the ... | 10/05/2010 |
| 7790025 | External gradient chromatofocusing The invention provides novel methods for the separation of charged molecules such as proteins according to the isoelectric points (pI's) and includes the systems and buffering compositions employed for isolating charged molecules. The invention further provides for ... | 09/07/2010 |