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| Number | Title | Issue Date |
| 7379765 | Oxygen enhancing membrane systems for implantable devices The present invention relates generally to systems and methods for increasing oxygen availability to implantable devices. The preferred embodiments provide a membrane system configured to provide protection of the device from the biological environment and/or a cata... | 05/27/2008 |
| 7361258 | Sensor element and gas sensor A flat limiting-current sensor 10 includes a solid electrolyte substrate 22, a negative electrode 34a and a positive electrode 32a. The negative and positive electrodes 34a and 32a, respectively, ... | 04/22/2008 |
| 7270730 | High-throughput electrophysiological measurement system Systems, including apparatus and methods, for performing electrophysiological measurements on membranous samples, including living cells, isolated cell fragments (such as organelles), and/or artificial membranes (such as vesicles). The apparatus may include a high-t... | 09/18/2007 |
| 7067046 | System for rapid chemical activation in high-throughput electrophysiological measurements An ultraviolet light source is added to a high-throughput electrophysiogical measurement system to allow for rapid chemical stimulation via caged compound release to a plurality of measurement samples. The integrated electrophysiogical measurement system includes a ... | 06/27/2006 |
| 7025871 | Reference electrode having a microfluidic flowing liquid junction A flowing junction reference electrode exhibiting heretofore unattainable potentiometric characteristics is described, comprising a microfluidic liquid junction member that is situated between a reference electrolyte solution and a sample solution. This microfluidic... | 04/11/2006 |
| 6936147 | Hybrid film type sensor A miniaturized gas sensor comprised of thick- or thin-film type electrodes, on a non-conductive supportive substrate, and in contact with a solid ionomer electrolyte, for the detection of toxic gases, i.e., carbon monoxide, and other oxidizable or reducible gases an... | 08/30/2005 |
| 6936462 | High throughput screen The present invention relates to a structure comprising a biological membrane and a porous or perforated substrate, a biological membrane, a substrate, a high throughput screen, methods for production of the structure membrane and substrate, and a method for screeni... | 08/30/2005 |
| 6872297 | Analytical instruments, biosensors and methods thereof An electrochemical sensor system and membrane and method thereof for increased accuracy and effective life of electrochemical and enzyme sensors. ... | 03/29/2005 |
| 6780649 | Photoluminescent semiconductor materials Semiconductor materials having a porous texture are modified with a recognition element and produce a photoluminescent response on exposure to electromagnetic radiation. The recognition elements, which can be selected from biomolecular, organic and inorganic moietie... | 08/24/2004 |
| 6746594 | Miniature support for thin films containing single channels or nanopores and methods for using the same Single-channel thin film devices and methods for using the same are provided. The subject devices comprise cis and trans chambers connected by an electrical communication means. At the cis end of the electrical communication means is a horizontal conical aperture se... | 06/08/2004 |
| 6630356 | Photoluminescent semiconductor materials Semiconductor materials having a porous texture are modified with a recognition element and produce a photoluminescent response on exposure to electromagnetic radiation. The recognition elements, which can be selected from biomolecular, organic and inorga... | 10/07/2003 |
| 6573109 | Surface amplifier The present invention relates to a membrane for use in detecting the presence of an analyte. The membrane comprises an array of closely packed self-assembling amphiphilic molecules and a plurality of first and second receptor molecules, the first receptor... | 06/03/2003 |
| 6514402 | Sensor and method for detecting an air borne or exogenously introduced analyte The present invention includes a method and sensor that is easy to assemble and can operate to effectively detect an air borne or exogenously introduced analyte. In one embodiment, the assembled sensor includes a top cap capable of receiving a first elect... | 02/04/2003 |
| 6451196 | Ionic reservoir through application of an electrical potential An improved membrane based biosensor incorporates sensing and reference electrodes and a dc electrical potential produced by a counter electrode. The biosensor incorporates ionophores. The conductivity of the membrane is dependent on the presence or absen... | 09/17/2002 |
| 6432296 | Polymeric compositions for ion-selective electrodes Improved dry-operative ion-selective electrodes and their use are described. The dry-operative ion-selective electrodes include an internal reference electrode comprising a water-soluble salt dispersed in a polymer binder consisting essentially of a monom... | 08/13/2002 |
| 6355158 | Method of measuring pH The present invention provides a means to substantially decrease the pH bias that is commonly observed with pH data obtained using ion selective electrode (ISE) containing instruments that have a solvent polymeric membrane based ISE pH electrode. The pH b... | 03/12/2002 |
| 6319375 | Apparatus for identifying a gas An apparatus for identifying an unknown reactive gas in a carrier gas, utilizing a sensor with a diffusion limited inlet. The apparatus includes a manifold of predetermined volume having an inlet and outlet, an inlet valve in the manifold inlet, an outlet... | 11/20/2001 |
| 6287452 | Electrode for the electrochemical detection of nitric oxide Nitric oxide-specific electrodes are useful for in situ detection of nitric oxide in biomedical applications and have at least a surface region thereof which is capable of forming complexes with nitric oxide, for example, nitrosyl complexes. The nitric ox... | 09/11/2001 |
| 6280604 | Electrode materials, systems and methods for the electrochemical detection of nitric oxide Nitric oxide-specific electrodes are useful for in situ detection of nitric oxide in biomedical applications and have at least a surface region capable of forming complexes with nitric oxide. The nitric oxide complexes formed at the surface of the electro... | 08/28/2001 |
| 6267872 | Miniature support for thin films containing single channels or nanopores and methods for using same Single-channel thin film devices and methods for using the same are provided. The subject devices comprise cis and trans chambers connected by an electrical communication means. At the cis end of the electrical communication means is a horizontal conical ... | 07/31/2001 |
| 6210551 | Composite membrane sensor The present invention provides a biosensor comprising an electrode and a membrane in which the biosensor includes at least two zones each zone differing from each other zone in a property. The membrane includes a plurality of ionophores, at least a propor... | 04/03/2001 |
| 6177000 | Biosensor comprising a lipid membrane containing gated ion channels A biosensor has a lipid membrane (7) containing gated ion channels sensitive to the presence or otherwise of an analyte molecule in a sample applied, in use, to a first side of the lipid membrane (7). The lipid membrane (7) is disposed between a pair of e... | 01/23/2001 |
| 6165347 | Method of identifying a gas A method and apparatus for identifying an unknown reactive gas in a carrier gas, utilizing a sensor with a diffusion limited inlet. After a signal is established for the carrier gas, a flow of the mixture of carrier gas and reactive gas is passed to the s... | 12/26/2000 |
| 6063260 | Patch clamp apparatus and technique having high throughput and low fluid volume requirements Apparatus for carrying out patch clamp technique utilized in studying the effect of certain materials on ion transfer channels in biological tissue, and more particularly patch clamp apparatus utilizing an autosampler, such as those utilized with HPLC app... | 05/16/2000 |
| 6039861 | Electrochemical reactions The invention provides an electrochemical reaction wherein a controlled amount of a first reagent is generated electrochemically at an electrode in electrical contact with a solution of an electrochemically inert salt, comprising applying a suitable elect... | 03/21/2000 |
| 6001239 | Membrane based electrochemical test device and related methods An electrochemical test device is provided for determining the presence or concentration of an analyte in an aqueous fluid sample. The electrochemical test device includes a working electrode and a counter electrode made of an amorphous semiconductor mate... | 12/14/1999 |
| 5980705 | Electrode for the electrochemical detection of nitric oxide Nitric oxide-specific electrodes are useful for in situ detection of nitric oxide in biomedical applications and have at least a surface region thereof which is capable of forming complexes with nitric oxide, for example, nitrosyl complexes. The nitric ox... | 11/09/1999 |
| 5942103 | Renewable-reagent electrochemical sensor A new electrochemical probe(s) design allowing for continuous (renewable) reagent delivery. The probe comprises an integrated membrane-sampling/electrochemical sensor that prevents interferences from surface-active materials and greatly extends the linear... | 08/24/1999 |
| 5932079 | Electrochemical multigas sensor An electrochemical measuring cell for the simultaneous detection of different gas components in a gas sample, with a plurality of measuring electrodes (4, 5, 6) behind a diffusion barrier (7), with a common reference electrode (8) and counterelectrode (9)... | 08/03/1999 |
| 5840171 | Electrochemical reactions The invention provides an electrochemical reaction wherein a controlled amount of a first reagent is generated electrochemically at an electrode in electrical contact with a solution of an electrochemically inert salt, comprising applying a suitable elect... | 11/24/1998 |
| 5814205 | Detection of lead in blood A device (10) is disclosed for measuring the concentration of metal ions in solution, particularly lead in blood. The device comprises a mercury free electrode (16), which is separated from the test solution (21) by a layer of material (20) which permits ... | 09/29/1998 |
| 5770038 | Method for detecting chemical substances A method for detecting and identifying a chemical substance in various phases such as a vapor phase and a liquid phase. The chemical substance being measured is diffused into a predetermined phase. Then, an electric state at an electrode existing in the p... | 06/23/1998 |
| 5725754 | Method of measuring the concentration of ions in solution A method of measuring the concentration of ions in a solution, for example the concentration of solvated H+ ions i.e. the pH, comprises applying an a. c. signal across an ion-sensitive material immersed in the solution and measuring the comple... | 03/10/1998 |
| 5626740 | Method of and apparatus for measuring electrolyte When determining an activity of particular predetermined ions in a sample liquid by use of a device for measuring ionic activity including a pair of ion-selective electrodes which are selectively responsive to particular predetermined ions, a pair of spot... | 05/06/1997 |
| 5624546 | Method and apparatus for the detection of toxic gases A compact electrochemical cell utilized for the detection of numerous toxic gases. The cell includes working and counter electrodes, surrounded by a liquid electrolyte, all of which is enclosed behind a gas permeable, hydrophobic membrane. The working ele... | 04/29/1997 |
| 5611904 | Electrochromatography apparatus The invention provides fittings for the ends of electrochromatography cols. Each fitting includes an annular electrode surrounding one end of the passage electrical fields to be applied. The fitting also contains a passageway for eluant flowing into or o... | 03/18/1997 |
| 5611908 | Method of operating and amperometric measuring cell The invention relates to a method for operating an amperometric measuring cell which includes at least a measuring electrode 2 and a counter electrode 3 in an electrolyte chamber 4 filled with an electrolyte. The measuring cell is closed off by a permeabl... | 03/18/1997 |
| 5611909 | Method for detecting source of error in an amperometric measuring cell The invention is directed to a method for detecting error sources in an amperometric measuring cell 1 which includes at least a measuring electrode 2 and a counter electrode 3 within an electrolyte chamber 4 filled with an electrolyte solution 6. A permea... | 03/18/1997 |
| 5560810 | Electrochemical gas sensor assembly An electrochemical gas sensor assembly comprises an electrochemical gas sensor for sensing a selected gas. A filter is provided through which gas to be sensed must pass before reaching the sensor, the filter being adapted to prevent at least one non-selec... | 10/01/1996 |
| 5558756 | Method for geo-electrochemical sampling This invention relates to a novel geo-electro-chemical sampling electrode and process. More specifically, this invention pertains to a novel ion collection electrode, and process, which can be used in the remote sampling of ions contained in ground water.... | 09/24/1996 |
