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| Number | Title | Issue Date |
| 8187443 | Apparatus for separating cell using centrifugal force and dielectrophoresis A cell separating apparatus that can easily separate target cells contained in a fluid is provided. Target cells and a fluid are injected through a storage hole, and ejected to the outside of a rotation disk under the influence of a centrifugal force of the rotation... | 05/29/2012 |
| 8057655 | Sub-micron object control arrangement and approach therefor Sub-micron objects are manipulated. According to an example embodiment of the present invention, Brownian motion effects are mitigated to facilitate the analysis and/or manipulation of sub-micron objects. In some applications, an electric field is applied to facilit... | 11/15/2011 |
| 8034226 | Device for dielectrophoretic separation of particles contained in a fluid A device for dielectrophoretic separation of particles contained in a fluid, includes two sets of electrodes, each of the two sets of electrodes being brought to a different potential, so as to generate an electric field inside said fluid. The two sets of electrodes... | 10/11/2011 |
| 8021532 | Dielectrophoretic tweezers apparatus and methods Dielectrophoretic (DEP) tweezers apparatus and methods for various applications, including particle trapping. Multiple electrodes (e.g., two or three) are disposed on or otherwise constitute an elongated object forming a tip. Exemplary electrode configurations inclu... | 09/20/2011 |
| 7998328 | Method and apparatus for separating particles by dielectrophoresis Methods and apparatus for the micro-scale, dielectrophoretic separation of particles are provided. Fluid suspensions of particles are sorted and separated by dielectrophoretic separation chambers that have at least two consecutive, electrically coupled planar electr... | 08/16/2011 |
| 7964078 | Microfluidic device for cell and particle separation A microfluidic separation device includes a microchannel formed in a substrate and being defined at least by a bottom surface, a first side wall, and second side wall. Fluid containing particles or cells is flowed through the microchannel from an upstream end to a d... | 06/21/2011 |
| 7935239 | Liquid moving apparatus A liquid moving apparatus is disclosed. The liquid moving apparatus may include a container having a holding chamber enclosed by first and second end walls facing against each other and side walls connecting the first and second end walls, a polarized or conductive ... | 05/03/2011 |
| 7931792 | System for concentrating and analyzing particles suspended in a fluid Disclosed is a device for separating and concentrating particles suspended in a fluid stream by using dielectrophoresis (DEP) to trap and/or deflect those particles as they migrate through a fluid channel. The method uses fluid channels designed to constrain a liqui... | 04/26/2011 |
| 7918981 | Cell isolation method and uses thereof This invention relates generally to the field of cell separation or isolation. In particular, the invention provides a method for separating cells, which method comprises: a) selectively staining cells to be separated with a dye so that there is a sufficient differe... | 04/05/2011 |
| 7862702 | Methods and apparatus for electrosmear analysis Methods and apparatus for preparing a smear for cytopathology or other analysis. In a representative embodiment, cells of a sample are subjected to a dielectrophoretic force to segregate the cells into two or more zones of a surface. The particles are attached to th... | 01/04/2011 |
| 7828950 | Dielectrophoresis apparatus including concentration gradient generating unit A dielectrophoresis (DEP) apparatus including a concentration gradient generating unit, a method of separating a target material in a sample solution using the DEP apparatus, and a method of screening the optimum condition for separating a target material are provid... | 11/09/2010 |
| 7811438 | Bio-enrichment device to enhance sample collection and detection A flow cell is disclosed for collecting and concentrating a sample dispersed in a flowing medium. The collected sample can be selectively manipulated within the cell by the use of one or more traveling wave grids. The cells are particularly useful as bio-enrichment ... | 10/12/2010 |
| 7811439 | Concentration and separation of biological organisms by ultrafiltration and dielectrophoresis Disclosed is a method for monitoring sources of public water supply for a variety of pathogens by using a combination of ultrafiltration techniques together dielectrophoretic separation techniques. Because water-borne pathogens, whether present due to “natural” ... | 10/12/2010 |
| 7744738 | Method and apparatus for rapid particle manipulation and characterization The present invention provides a method and apparatus for use in rapid particle transportation, separation, focusing, characterization, and release. Dielectrophoresis and electro-osmotic driven fluid convection are used independently or in tandem as the driving forc... | 06/29/2010 |
| 7713395 | Dielectrophoretic columnar focusing device A dielectrophoretic columnar focusing device uses interdigitated microelectrodes to provide a spatially non-uniform electric field in a fluid that generates a dipole within particles in the fluid. The electric field causes the particles to either be attracted to or ... | 05/11/2010 |
| 7666289 | Methods and devices for high-throughput dielectrophoretic concentration Disclosed herein are methods and devices for assaying and concentrating analytes in a fluid sample using dielectrophoresis. As disclosed, the methods and devices utilize substrates having a plurality of pores through which analytes can be selectively prevented from ... | 02/23/2010 |
| 7534336 | Continuous flow particle concentrator An apparatus for extracting and concentrating bioagents within a continuously flowing fluid medium includes a flow channel fluid inlet, in which bioagents are concentrated from three dimensions to a two-dimensional transport layer in a preconcentration area. Traveli... | 05/19/2009 |
| 7491307 | Portable bioagent concentrator A portable apparatus for extracting and concentrating bioagents within a fluid medium includes a container with sample solution inlet port and traveling wave grids patterned on surfaces of the container. The traveling wave grids cause bioagents to migrate to a speci... | 02/17/2009 |
| 7435579 | Biosensor and related method A microscale biosensor for use in the detection of target biological substances includes a detection chamber disposed on the substrate and defining a volume between 1 pico-liter and 1 micro-liter. The detection chamber is adapted to confine a composition containing ... | 10/14/2008 |
| 7425253 | Microscale sorting cytometer The present invention provides a device and methods of use thereof in microscale cell sorting. This invention provides sorting cytometers, which trap individual cells within vessels following exposure to dielectrophoresis, allow for the assaying of trapped cells, su... | 09/16/2008 |
| 7419574 | Dielectrophoresis device and method having non-uniform arrays for manipulating particles Microfluidic devices according to embodiments of the present invention include an inlet port, an outlet port, and a channel or chamber having a non-uniform array of insulating features on one or more surfaces. Electrodes are provided for generation of a spatially no... | 09/02/2008 |
| 7399395 | Method and device for generating microconvections The invention relates to a method for generating a convective liquid motion in a fluidic microsystem. According to this method, a liquid in a microsystem is simultaneously exposed to an electrical field and a thermal gradient. The electrical field is generated by me... | 07/15/2008 |
| 7390387 | Method of sorting cells in series A method of sorting cells comprises providing a fluid flow path for cell movement through a series of cell sorters in a first direction with an output of a preceding cell sorter of the series communicating with an input of a successive cell sorter of the series. Wit... | 06/24/2008 |
| 7390388 | Method of sorting cells on a biodevice A method of sorting cells for a biodevice comprises directing a flow of cells within a fluid into a filtration structure defining an array of fluid openings and encouraging cell passage of each cell of a portion of the cells through the fluid openings based on at le... | 06/24/2008 |
| 7384791 | Method of analyzing blood A method of analyzing blood includes delivering a blood sample to a test device, applying a spatially varying electric field to the blood sample to provide a depleted cell concentration in a portion of the blood sample, and sensing a property of the portion of the b... | 06/10/2008 |
| 7384780 | Hybridization method and hybridization equipment The equipment of the present invention can implement high-speed hybridization with a simple construction and is configured as described below. The equipment comprises a biochip prepared by fixing biopolymers onto a plurality of sites on a substrate, positive ... | 06/10/2008 |
| 7347923 | Dielectrophoresis device and method having insulating ridges for manipulating particles Embodiments of the present invention provide methods and devices for manipulating particles using dielectrophoresis. Insulating ridges and valleys are used to generate a spatially non-uniform electrical field. Particles may be concentrated, separated, or captured du... | 03/25/2008 |
| 7309410 | Traveling wave grids and algorithms for biomolecule separation, transport and focusing Various traveling wave grids and related systems are disclosed that are particularly beneficial for the separation, transport, and focusing of biomolecules or other charged species. An implementation of a vertically integrated traveling wave module is described whic... | 12/18/2007 |
| 7306924 | Biosensor and related method A method for collecting a microbiological substance utilizes a micro fabricated biochip having a collection chamber. A fluid sample containing a microbiological entity of interest is delivered to the collection chamber in the biochip. Then a non-uniform electric fie... | 12/11/2007 |
| 7304258 | System for transporting and selectively sorting particles and method of using the same A system for transporting and selectively sorting particles includes a first wall and a traveling wave grid extending along the first wall. The system includes a second wall having a passage extending therethrough and a gate operatively associated with the passage. ... | 12/04/2007 |
| 7294249 | Microfluidic component and method for sorting particles in a fluid Microtechnologically prepared component as a flow cytometer. The component contains a preparation area to specifically influence and separate the particles, preferably by dielectrophoresis, a measuring channel area for characterizing the particles, and a sorting are... | 11/13/2007 |
| 7267752 | Rapid flow fractionation of particles combining liquid and particulate dielectrophoresis Rapid, size-based, deposition of particles from liquid suspension is accomplished using a nonuniform electric field created by coplanar microelectrode strips patterned on an insulating substrate. The scheme uses the dielectrophoretic force both to distribute aqueous... | 09/11/2007 |
| 7250110 | Electro-kinetic water conditioning A method for treating hard water comprising the steps of flowing water containing suspended colloidal mineral particles through a confined treatment zone, applying an electrical potential across the flowing water to cause electrical current to flow through the water... | 07/31/2007 |
| 7244360 | Water treatment process The present invention provides a physical water treatment (PWT) method and apparatus to treat liquid coolants. Electrodes (22, 24) are provided in a coolant stream (21), and an alternating voltage is applied across the electrodes (22, 24) to pro... | 07/17/2007 |
| 7214302 | Method and device for moving and placing liquid drops in a controlled manner The invention relates to a method and a device which serves for moving and dosing amounts of liquid on a microscopic scale with a volume of especially 10−12 to 10−6 liters by means of an inhomogeneous electric field using a support having a... | 05/08/2007 |
| 7211183 | Analysis and fractionation of particles near surfaces A method and apparatus for fractionation of a mixture of particles and for particle analysis are provided, in which LEAPS (“Light-controlled Electrokinetic Assembly of Particles near Surfaces”) is used to fractionate and analyze a plurality of particles suspende... | 05/01/2007 |
| 7204923 | Continuous flow dielectrophoretic particle concentrator A continuous-flow filter/concentrator for separating and/or concentrating particles in a fluid is disclosed. The filter is a three-port device an inlet port, an filter port and a concentrate port. The filter separates particles into two streams by the ratio of their... | 04/17/2007 |
| 7198702 | Method for separating substances using dielectrophoretic forces The present invention has an object of providing a method by which two kinds or more of molecules can be separated each other by using dielectrophoretic forces. The present invention comprises two methods. The first method is a method comprising forming a complex su... | 04/03/2007 |
| 7176018 | Cell lysis device A micromachined cell lysis device with electrodes that are spaced by less than 10 μm from one another. The cells are attracted to the space between the electrodes and then lysed. ... | 02/13/2007 |
| 7175748 | Subsea production system A subsea well fluid processing system has a separator for separating heavier and lighter components of well fluid flowing from a subsea well and directing the lighter components to flow to a surface processing facility. A choke is located downstream of the separator... | 02/13/2007 |
