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| Number | Title | Issue Date |
| 7425254 | Fractionation of macro-molecules using asymmetric pulsed field electrophoresis A method and apparatus for fractionation of charged macro-molecules such as DNA is provided. DNA solution is loaded into a matrix including an array of obstacles. An alternating electric field having two different fields at different orientations is applied. The alt... | 09/16/2008 |
| 7413908 | Gel extraction device A gel extraction device comprising a hollow cutting member having a cutting edge at one end and a squeeze bulb at the other end. In a further embodiment, the air passage between the cutting edge and the bulb has a constriction zone to prevent any extracted gel from ... | 08/19/2008 |
| 7357852 | Bubble-free and pressure-generating electrodes for electrophoretic and electroosmotic devices Bubble-free electrodes, electrochemical cells including bubble-free electrodes, analytical devices, and methods for preparing and using them are provided. The analytical devices each include at least one bubble-free electrode. Analytical devices that include an elec... | 04/15/2008 |
| 7338583 | Electrophoresis apparatus, and method of analysis Analysis is performed efficiently in an electrophoresis apparatus while avoiding deterioration of samples. A plurality of sample plates are stored in frozen storage. When a particular sample plate is being analyzed, other sample plates are stored in a standby unit. ... | 03/04/2008 |
| 7261800 | Automatic in situ electrophoresis method and apparatus A method of in situ electrophoresis of biological samples has the steps of preparing a sample plate and a gel plate, applying reagent onto the gel plate, moving an applicator to the sample plate so as to receive a sample onto the applicator, moving the applicator to... | 08/28/2007 |
| 7250097 | Device for sequential protein transfer from a gel An apparatus and method for the sequential electroelution of biomolecules is described, the apparatus comprising a separation medium having an outlet, and a collector having at least a first receptacle and a second receptacle that can be sequentially brought into co... | 07/31/2007 |
| 7247275 | Gel extraction device A gel extraction device comprising a hollow cutting member and a plunger ejector member. The hollow cutting member has a proximal tubular body terminating at one end in a circular rim having oppositely disposed spring engaging structures and a distal sloped transiti... | 07/24/2007 |
| 7153404 | Gel spot picker The present invention relates to a gel sheet (1) for use in a spot picker device wherein said gel sheet is provide with reference marks (5′–5′″) which can be used to determine if the gel sheet (1) has been deformed between the stages of ... | 12/26/2006 |
| 7153405 | Cassette, system, and 2-D gel electrophoresis method for separating molecules A gel electrophoresis cassette (33) is disclosed which includes two plates (34, 35) and at least one seal (36) which separates these plates. The seal (36) is annular; it may be positioned essentially in the region of the outer edge of the... | 12/26/2006 |
| 7147762 | Method of electrophoresis The present invention relates a method of electrophoretic separation of protein and/or peptide components of a sample in a convection stabilized medium. More specifically, the method comprises the steps to contact the sample with the separation medium; to apply a vo... | 12/12/2006 |
| 7077940 | Strip holder, chamber, cassette, and 2-D gel electrophoresis method and system for performing this method for separating molecules A strip holder (1) is disclosed for accommodating a gel strip (3) for separating molecules using gel electrophoresis. The strip holder (1) disclosed is distinguished by including a baseplate (4), at least one stop (5), which is off... | 07/18/2006 |
| 7074313 | Processing chamber A device having a processing chamber, for electroelution and/or dialysis of a substance carried in a sample with respect to an external liquid medium. The chamber has a closed end and an opening at the other end, sufficiently large to permit a sample, particularly a... | 07/11/2006 |
| 7070682 | Microfluidic apparatus for performing gel protein extractions and methods for using the apparatus The invention relates to an apparatus for performing gel protein extractions and methods of using the apparatus. ... | 07/04/2006 |
| 7060172 | Electrophoresis gel and gel-forming apparatus The apparatus includes a container (20) having a base (22) and sides (32) adapted to receive a plurality of plastic gel cassettes. An inlet port (12) is positioned in the base of the container and in fluid communication with the chamber a... | 06/13/2006 |
| 7025864 | Method and apparatus for recovering target molecules from a gel containing said target molecules A preparative electrophoresis apparatus suitable for recovery of molecules from gels comprises two spaced apart electrode compartments connected by a conduit that descends from the bottom of the electrode compartments in a V-shaped or U-shaped form. The conduit serv... | 04/11/2006 |
| 6991714 | Apparatus and method for taking samples from polymer support material A sample taking apparatus comprises a plurality of separation tools (10) (for example, punching capillaries) on a holding device (20), wherein the separation tools (10) are each provided with actuating means (30) for separate control ther... | 01/31/2006 |
| 6974526 | Plastic microfluidics enabling two-dimensional protein separations in proteome analysis The invention provides a microfluidic apparatus for performing 2-D biomolecular separations. The microfluidic 2-D device may include first and second planar substrates which include at least a first dimension microchannel extending in a first direction and an array ... | 12/13/2005 |
| 6932895 | Automated electrophoresis gel manipulation apparatus An automated, computer controlled assembly is provided for continuously processing a large number of electrophoresis gels. The assembly includes a loading assembly for loading a gel onto a carrier, a gel staining assembly and a scanning and cutting assembly. The sta... | 08/23/2005 |
| 6929730 | Two dimensional microfluidic gene scanner One embodiment of the invention relates to a microfluidic apparatus for performing two dimensional biomolecular separations. According to one aspect of the invention, after a first dimension separation in a first microchannel, the sample material is electrokinetical... | 08/16/2005 |
| 6926815 | Copolymers for capillary gel electrophoresis This invention relates to an electrophoresis separation medium having a gel matrix of at least one random, linear copolymer comprising a primary comonomer and at least one secondary comonomer, wherein the comonomers are randomly distributed along the copolymer chain... | 08/09/2005 |
| 6922081 | Electronic circuit, sensor arrangement and method for processing a sensor signal In a first phase a first sensor signal, essentially comprising the current offset signal of the sensor, is applied to the input of an electronic circuit. The first sensor signal is fed to a first signal path and stored therein. In a second phase a second sensor sign... | 07/26/2005 |
| 6793790 | Sample collection system for gel electrophoresis An automatic sample collection system for use with an electrophoretic slab gel system is presented. The collection system can be used with a slab gel have one or more lanes. A detector is used to detect particle bands on the slab gel within a detection zone. Such de... | 09/21/2004 |
| 6783648 | Method and apparatus for unloading gels from isoelectric gel tubes An apparatus for expressing and unloading an isoelectric focusing gel from an electrophoresis gel tube includes a first support for supporting the gel tube, a plunger rod and a second support for supporting the plunger rod. The first support is mounted on a movable ... | 08/31/2004 |
| 6702990 | Spot picker A spot picker is comprised of a pipette and a disposable cutting tip. The pipette is comprised of a housing with a suction tube projecting from a lower end. An actuation button is positioned at the top end of the housing. The actuation button is connected... | 03/09/2004 |
| 6652724 | Automated apparatus for separating a biological sample from a two dimensional electrophoresis gel An automated high-throughput system for excising spots or samples from an electrophoresis slab gel includes a computer controlled robotic arm assembly and a sample plate handling assembly for supplying a sample plate to a loading station. The computer is ... | 11/25/2003 |
| 6632339 | Method of identifying polypeptides Polypeptides which have been separated by gel electrophoresis can be identified by electroblotting them through a "sandwich" comprising in order: a) the separation gel; b) at least one hydrophilic membrane, e.g. of carboxyl-modified PVDF, on which... | 10/14/2003 |
| 6602391 | Apparatus and method for combined capillary separation and blotting of biological macromolecules An apparatus and method are described for capillary separation of macromolecules and precise post-separation blotting. Apparatus include disposable separating element (capillary), which contains a sieving or interaction matrix inside, an external layer of... | 08/05/2003 |
| 6565728 | Gel cutting and recovering device The device of present invention is used for cutting and recovery of a selected gel piece from a larger gel mass. The gel piece suitably contains molecules that will be used in further work. The preferred device is made up of at least two parts: a hollow m... | 05/20/2003 |
| 6554991 | Automated system for two-dimensional electrophoresis The present invention provides an integrated, fully automated, high-throughput system for two-dimensional electrophoresis comprised of gel-making machines, gel processing machines, gel compositions and geometries, gel handling systems, sample preparation ... | 04/29/2003 |
| 6540897 | Direct detection of histidine tagged biomolecules on electrophoretic gel A method is disclosed for the detection of a His-tagged target biomolecule while said molecule remains in the gel in which it has been separated from other constituents by electrophoresis. The method involves, while the separated His-tagged biomolecule re... | 04/01/2003 |
| 6482303 | Automated system for two-dimensional electrophoresis The present invention provides an integrated, fully automated, high-throughput system for two-dimensional electrophoresis comprised of gel-making machines, gel processing machines, gel compositions and geometries, gel handling systems, sample preparation ... | 11/19/2002 |
| 6451189 | Automated system for two dimensional electrophoresis The present invention provides an integrated, fully automated, high-throughput system for two-dimensional electrophoresis comprised of gel-making machines, gel processing machines, gel compositions and geometries, gel handling systems, sample preparation ... | 09/17/2002 |
| 6416644 | Automated system for two-dimensional electrophoresis The present invention provides an integrated, fully automated, high-throughput system for two-dimensional electrophoresis comprised of gel-making machines, gel processing machines, gel compositions and geometries, gel handling systems, sample preparation ... | 07/09/2002 |
| 6398932 | Automated system for two-dimensional electrophoresis The present invention provides an integrated, fully automated, high-throughput system for two-dimensional electrophoresis comprised of gel-making machines, gel processing machines, gel compositions and geometries, gel handling systems, sample preparation ... | 06/04/2002 |
| 6342143 | Cutting tool for multiple sample retrieval from gelatinous material The invention relates to a sample retrieval apparatus of particular benefit in the field of molecular biology. The apparatus permits the rapid collection of numerous specified fractions of samples: such as DNA, RNA or protein, that are separated by gel el... | 01/29/2002 |
| 6203680 | Electrophoresis gels The present invention provides electrophoresis apparatus and electrophoresis methods employing gellan gum based gels employing divalent metal cation and diamine cross-linking agents. The gels are reversible under conditions that do not damage the biomolec... | 03/20/2001 |
| 6203679 | Electrophoresis gel container apparatus and method of use thereof An electrophoresis container apparatus having (1) a primary container tray made from a UV light transmitting materials, (2) a UV light transmitting gel contained in the primary container tray, and (3) a removable top sheet for covering the gel. The remova... | 03/20/2001 |
| 6068754 | Multi-tank gel developing apparatus and method The claimed multi-tank gel developing apparatus and method comprises of two inner tanks within one outer tank to develop multiple electrophoresis gels simultaneously. The two inner tanks have openings along the edges of the walls to allow free circulation... | 05/30/2000 |
| 5928880 | Mesoscale sample preparation device and systems for determination and processing of analytes A mesoscale sample preparation device capable of providing microvolume test samples, separated into a cell-enriched fraction and a fraction of reduced cell content, for performing various analyses, such as binding assays, determinations involving polynucl... | 07/27/1999 |
| 5882495 | Electrophoresis system The present invention provides electrophoresis systems and methods for forming at least one gel therein and for conducting electrophoresis on the gel without removing the gel from the electrophoresis system. The systems of the present invention include an... | 03/16/1999 |
