Did You Know...
...that while attempting to develop a super strong glue, 3M employee Spencer Silver accidentally developed a glue that was so weak it would barely hold two pieces of paper together? However, his colleague Art Fry needed the glue. Fry sang with his church choir and marked the pages of his hymnal with small scraps of paper that often fell out. He used Silver's glue to hold the papers in place. Today we call this invention Post-it Notes.
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| Number | Title | Issue Date |
| 8034225 | Pulsed field gel electrophoresis chambers, accessories and methods of use for the separation of DNA molecules Methods of use, accessories and chambers, optimal for performing Pulsed Field Gel Electrophoresis (PFGE) of DNA molecules in ‘Contour Clamped Homogeneous Electric Field’ (CHEF) and ‘Transversal Alternating Field Electrophoresis’ (TAFE) systems, are provided ... | 10/11/2011 |
| 7556726 | Circuit for imposing voltages on the electrodes of trays used in the CHEF pulsed field electrophoresis system Circuit to clamp the voltages in the electrodes of the CHEF system chambers of Pulsed Field Gel Electrophoresis (PFGE) which is formed by two identical clamping circuits that are connected to a power supply through an alternator and only one of the two circuits rece... | 07/07/2009 |
| 7425254 | Fractionation of macro-molecules using asymmetric pulsed field electrophoresis A method and apparatus for fractionation of charged macro-molecules such as DNA is provided. DNA solution is loaded into a matrix including an array of obstacles. An alternating electric field having two different fields at different orientations is applied. The alt... | 09/16/2008 |
| 7309410 | Traveling wave grids and algorithms for biomolecule separation, transport and focusing Various traveling wave grids and related systems are disclosed that are particularly beneficial for the separation, transport, and focusing of biomolecules or other charged species. An implementation of a vertically integrated traveling wave module is described whic... | 12/18/2007 |
| 7282127 | Microcapillary devices using high dielectric constant materials and related methods A microcapillary device includes a microcapillary tube. An anode is positioned at a first end of the microcapillary tube. A cathode is positioned at a second end of said microcapillary tube. A plurality of electric field reducing components are spaced apart along a ... | 10/16/2007 |
| 6866759 | Stepped electrophoresis for movement and concentration of DNA A fluidic channel patterned with a series of thin-film electrodes makes it possible to move and concentrate DNA in a fluid passing through the fluidic channel. The DNA has an inherent negative charge and by applying a voltage between adjacent electrodes the DNA is c... | 03/15/2005 |
| 6103084 | Apparatus for electroporation An apparatus for electroporation stores a level of charge, specified by a user, on a capacitor, which is delivered to a cuvette through an optically isolated high voltage switch. The capacitor is charged through a charging system, including a current mode... | 08/15/2000 |
| 5846394 | Method and apparatus for carrying out electrophoresis in fractal fields A method and apparatus for carrying out electrophoretic separation is provided which imparts a fractal field component to the particles themselves or to the medium in which the particles are to be separated which, in combination with a steady field compon... | 12/08/1998 |
| 5667654 | Real time in-gel assay Methods are provided for assaying electrophoretically separated components of sample in a gel. Following an initial separation phase of the sample components into distinct bands within separate zones of the gel, the separated components are held stationar... | 09/16/1997 |
| 5405519 | Pulsed oriented electrophoresis Disclosed herein is a method of electrophoretically separating particles by the application to pulsed field electrophoresis of a pulsing routine in which the pulses are modulated in such a way as to define the effective field angle of the particles underg... | 04/11/1995 |
| 5336383 | Pulsed field gel electrophoresis of large DNA To separate high-molecular DNA strands, an electrophoresis system includes first means for changing the direction of an electric field within an electrophoresis separating unit at a first frequency having a period of no more than 20 seconds and second mea... | 08/09/1994 |
| 5167790 | Field-inversion gel electrophoresis A method and apparatus for gel electrophoresis which employs periodic inversion of the electric field essentially in one dimension, denoted as field-inversion gel electrophoresis (FIGE), results in net migration by using a longer time or higher voltage in... | 12/01/1992 |
| 5126022 | Method and device for moving molecules by the application of a plurality of electrical fields Devices and methods are disclosed for moving charged molecules through a medium by the application of a plurality of electrical fields of sufficient strength and applied for sufficient amounts of time so as to move the charged molecules through the medium... | 06/30/1992 |
| 5122248 | Pulsed field capillary electrophoresis Apparatus and method for conducting electrophoresis in a capillary tube under the influence of a pulsed electric field. Apparatus for separating and detecting molecular species of a sample in a conductive medium includes a capillary tube for containing co... | 06/16/1992 |
| 5108567 | Electrophoresis method and apparatus with orthongonal field A pulsed field electrophoresis method and apparatus for the separation of molecules wherein a fixed polarity potential difference between an anode and a cathode, disposed at respective opposed edges of the gel, produces a fixed polarity electric field in ... | 04/28/1992 |
| 5084157 | Gel electrophoresis using time dependent contour controlled electric fields An apparatus for separating particles within a medium which is capable of generating electric fields having adjustable magnitudes and orientations is disclosed herein. The electrophoretic apparatus of the present invention includes electrode arrangement f... | 01/28/1992 |
| 5047136 | Apparatus for electrophoretic separation of high-molecular DNAs in a gel The apparatus comprises electrophoresis chamber (1) with positioned therein along the sides of a rectangle electrode groups (2,3,4,5) of equidistantly positioned electrodes. One pair of subtending electrode groups (2,4) is connected to power supply (8), t... | 09/10/1991 |
| 5028308 | Apparatus for the electrophoretic separation of high-molecular DNA in gel An apparatus has an electrophoretic chamber in which groups of electrodes are positioned along sides of an equilateral quadrangle. Electrodes within each group are positioned in equally spaced relation to one another and are connected to a power supply vi... | 07/02/1991 |
| 5027018 | High voltage electrophoresis apparatus A high voltage switch for use in electrophoresis equipment is described. A solid state switch element is triggered by a continuous DC voltage derived from an isolated and rectified AC trigger signal. The gate of solid state element is connected by a low i... | 06/25/1991 |
| 4995957 | Device and method for the electrophoretic separation of macromolecules An electrophoretic separation apparatus suitable for the separation of macromolecules is provided. Electrode elements are provided for generating an electric field for acting on a specimen. Rotating elements are provided for rotating the electrode element... | 02/26/1991 |
| 4911817 | Electrophoresis apparatus In an apparatus for electrophoresis, using a support for a gel and a liquid buffer, a plurality of driving electrodes arrayed in spaced relation to one another so as to contact the medium, and a plurality of sensing electrodes arrayed in spaced relation t... | 03/27/1990 |
| 4886589 | Electrophoresis method and apparatus for separating particles in a separation medium Electrophoresis method and apparatus for separating particles in a separan medium (15) in which provided for driving the particles alternatively in different directions in the separation medium (15). The separation medium (15) is rotated at predetermined... | 12/12/1989 |
| 4740283 | Pulsed-field gradient gel electrophoretic apparatus A pulsed-field gradient gel electrophoretic apparatus is described wherein a free standing gel is employed. Electrode arrays are oriented to provide three dimensional fields across the face of the gel rather than in the plane of the gel. The electrodes pr... | 04/26/1988 |
| 4473452 | Electrophoresis using alternating transverse electric fields Disclosed are an apparatus for and a method of electrophoretically separating particles by electric fields which are transverse to each other, which alternate between respective high and low intensities out of phase with each other at a frequency related ... | 09/25/1984 |
