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Class 204/605 - Gel filled


Subclass of Class 204 - Chemistry: electrical and wave energy
Definition: Apparatus in which the inner bore of the capillary is filled
No. of patents: 159
Last issue date: 07/12/2011


1        
NumberTitleIssue Date
7976691Fabrication and use of semipermeable membranes and gels for the control of electrolysis
A microfluidic device and method is disclosed having one or more membranes for the control of electrolysis. In one embodiment, a microfluidic device is disclosed that includes body with first channel and second channels separated by a gel layer. A first electrode po...
07/12/2011
7531076Capillary cassette and method of manufacturing the same
Capillary columns (102) pass through and are inserted in a rubber plate (14), held and fixed by elastic force of rubber, and two-dimensionally arranged on a sample injection side. it fixes the capillary columns (102) arranged on a plane in close...
05/12/2009
7527720Device for electrophoresis, electrophoresis equipment, electrophoretic method, and specimen detection method
An electrophoretic device in the form of a casing having inside sealed spaces isolated by an electrophoretic carrier. The device includes at least one liquid injection/discharge opening, communicable with the outside, on the outer wall of said sealed spaces. An elec...
05/05/2009
7439075Method and device for withdrawing suspended microparticles from a fluidic microsystem
A method of discharging a fluid flow with suspended microparticles from a fluidic microsystem (10) is described, whereby the fluid flow converges with at least one output flow to form a discharge flow at the end of a discharge channel (14) of the micro...
10/21/2008
7419578Capillary electrophoresis apparatus
A capillary array electrophoresis which can measure fluorescence of a number of capillaries at a time with high sensitivity and can automatically analyze a sample sequentially. An end edge as a sample dissolution edge of a number of capillaries is connected to a pol...
09/02/2008
7402229Fabrication and use of semipermeable membranes and gels for the control of electrolysis in a microfluidic device
A microfluidic device and method is disclosed having one or more membranes for the control of electrolysis. In one embodiment, a microfluidic device is disclosed that includes body with first channel and second channels separated by a gel layer. A first electrode po...
07/22/2008
7381317Methods and compositions for capillary electrophoresis (CE)
This invention relates to improved methods and compositions for conducting Capillary Electrophoresis (CE) to separate molecules on the basis of their respective size or charge. ...
06/03/2008
7316770Method of electrophoresis, electrophoresis apparatus and capillary array
A method of electrophoresis, an electrophoresis apparatus and a capillary array in which a fluorescently labelled sample is supplied into capillaries in a capillary array constituted by a plurality of capillaries and including a sample supply portion, an electrophor...
01/08/2008
7314550Analytical separations with polyelectrolyte layers, molecular micelles, or zwitterionic polymers
Polymeric surfactants (molecular micelles) are disclosed for use in open tubular capillary electrochromatography or in high performance liquid chromatography. For example, fused silica capillaries are coated with thin films of charged polymers in a polyelectrolyte m...
01/01/2008
7309409Multi-channel bio-separation cartridge
A bio-separation system using an efficient, compact, portable, interchangeable, reusable, recyclable, multi-channel cartridge, has integrated pre-aligned optics and an integrated reagent reservoir. The cartridge supports, for example, multiple capillaries for CE sep...
12/18/2007
7294247Electrophoretic separating device and method for using the device
The invention concerns to an electrophoretic separation device comprising a separation channel having at least one in- and outlet opening at the beginning and at the end of the channel and one electrode in the region of the inlet opening and one electrode in the reg...
11/13/2007
7223326Capillary electrophoresis system
A capillary electrophoresis system includes a plurality of capillaries arranged in parallel on a vertical plane at an identical distance from each other, each of which has a sample injection end immersed in a cathode buffer 23 and pointed downward vertically ...
05/29/2007
7217352Capillary electrophoresis device
An electrophoresis device is disclosed that is capable of reducing waves occurring in a fluid in which the capillary tips of a capillary assay are immersed. A plurality of partition plate members can be provided in a container containing the fluid to divide the surf...
05/15/2007
7208072Multi-segment cartridge for bio-separation with multiplexed fluorescence detection
A bio-separation instrument using a multi-segment cartridge. The cartridge includes a plurality of efficient, compact, portable, interchangeable, reusable, recyclable, modular, multi-channel segments. Each segment supports multiple capillaries for CE separation. Eac...
04/24/2007
7195698Capillary electrophoretic apparatus, sample plate and sample injection method
An electrode plate of a sample plate is set on the body of an electrophoretic apparatus, while a plug is inserted into a migration high voltage line connection hole and connected to a high-tension distribution cable. Each well of a base plate is inserted into a thro...
03/27/2007
7179357Serial sample injection in capillary electrophoresis
The invention is a method of performing electrophoresis that increases sample throughput and increases the efficiency and speed of the analysis of polynucleotides by electrophoresis. The method is performed by loading and running multiple sequential samples on each ...
02/20/2007
7169277High throughput separations based analysis systems
Devices, systems and methods for use in separating sample materials into different fractions that employ bulk fluid flow for loading of samples followed by electrophoretic separation of the sample material. Devices employ configurations that optionally allow bulk sa...
01/30/2007
7163610Conductive media for electrophoresis
A series of low molarity conductive media based on non-buffering univalent cations, such as sodium chloride-sodium acetate (SCA), sodium boric acid (SB), lithium boric acid, and lithium acetate mitigate the “runaway” positive feedback heating loop produced by co...
01/16/2007
7156969Microfluidic matrix localization apparatus and methods
Multiphasic microfluidic apparatus for performing product fluid manipulation and separation in a single continuous unit are provided. Related methods, kits, and compositions are also provided. ...
01/02/2007
7153403Protein market pellets and method of making and using the same
A protein marker pellet for use in a gel electrophoresis system includes one or more protein markers including a protein of known molecular weight with ionic components to provide electrical conductance, and a non-protein, gel-forming material having a porosity suff...
12/26/2006
7147764Dual electrode injection of analyte into a capillary electrophoretic device
An injection system including a first electrical circuit for concentration of an analyte and a second electrical circuit for injection of the concentrated analyte into an electrophoretic device is described, as well as methods of using the injection system. ...
12/12/2006
7135144Method for the manipulation of a fluid sample
The invention provides a device and method for the manipulation of materials (e.g., particles, cells, macromolecules, such as proteins, nucleic acids or other moieties) in a fluid sample. The device comprises a substrate having a plurality of microstructures and an ...
11/14/2006
7083711Capillary electrophoresis gel especially for separation made for single stranded nucleic acid separations
A separation matrix for capillary electrophoresis of single-stranded nucleic acids is disclosed. The matrix comprises an aqueous buffer containing a denaturant and (hydroxypropyl)methyl cellulose. ...
08/01/2006
7081191Capillary electrophoresis device
The capillary electrophoresis device using one pressure-resistant syringe (125) is capable of automatically suctioning in polymer solution and injecting polymer solution into a capillary array (100). An electric hook (131) is installed for pulli...
07/25/2006
7081190Methods and compositions for performing molecular separations
The present invention provides methods of electrophoretically separating macromolecular species, as well as compositions and systems useful in carrying out such methods. Specifically, the methods of the present invention comprise providing a substrate that has at le...
07/25/2006
7059352Triggerable passive valve for use in controlling the flow of fluid
The present invention is directed to valves for use in controlling the flow of fluid and, more particularly, to a triggerable passive valve for use in controlling the flow of fluid. In one embodiment, a fluid delivery channel is connected to a flow restrictor and a ...
06/13/2006
7055540Method of moving fluid in capillary chip
The present invention is a method of moving a fluid in a capillary using a capillary chip having a layer including a polymer composition and a capillary formed on the surface or inside of the aforementioned layer including a polymer composition, wherein the aforemen...
06/06/2006
7052608Cast-to-shape electrokinetic trapping medium
A three-dimensional microporous polymer network material, or monolith, cast-to-shape in a microchannel. The polymer monolith, produced by a phase separation process, is capable of trapping and retaining charged protein species from a mixture of charged and uncharged...
05/30/2006
7041208Microfluidic devices and methods for two-dimensional separations
A microfluidic device includes first and second substrates and a microfluidic cavity formed in one of the first and second substrates. The microfluidic cavity has a width (W) and a depth (D), wherein the other of the first and second substrates encloses the microflu...
05/09/2006
7018520Concentration and cleanup of nucleic acid samples
Methods and devices are described for concentration and cleanup of samples containing bio-molecule analytes (e.g., polynucleotides, such as DNA, RNA, PNA). Various embodiments provide for pH-mediated sample concentration and cleanup of nucleic acid samples with chan...
03/28/2006
7014745Capillary cassette and method of manufacturing the same
Capillary columns (102) pass through and are inserted in a rubber plate (14), held and fixed by elastic force of rubber, and two-dimensionally arranged on a sample injection side. It fixes the capillary columns (102) arranged on a plane in close...
03/21/2006
6998251Nanoporous membrane reactor for miniaturized reactions and enhanced reaction kinetics
Reactors and methods for miniaturized reactions having enhanced reaction kinetics. In particular the subject matter is directed to chemical and biological reactions conducted in a nanoporous membrane environment. The subject matter contemplates methods for modifying...
02/14/2006
6991713Methods and apparatus for processing a sample of biomolecular analyte using a microfabricated device
A technique processes a sample of biomolecular analyte. The technique uses an apparatus having a support assembly that receives and supports a test module, a load assembly that loads the sample of biomolecular analyte onto the test module, an electrophoresis assembl...
01/31/2006
6953521Automated parallel capillary electrophoresis system with hydrodynamic sample injection
An automated capillary zone electrophoretic system is disclosed. The system employs a capillary cartridge having a plurality of capillary tubes. The cartridge has a first array of capillary ends projecting from one side of a plate. The first array of capillary ends ...
10/11/2005
6942778Microstructure apparatus and method for separating differently charged molecules using an applied electric field
The field of the present invention relates generally to a microstructure apparatus which may be used in a high-throughput screening context to monitor the rate of reaction of an enzyme with its substrate in cases where the product of the reaction has an altered net ...
09/13/2005
6926815Copolymers for capillary gel electrophoresis
This invention relates to an electrophoresis separation medium having a gel matrix of at least one random, linear copolymer comprising a primary comonomer and at least one secondary comonomer, wherein the comonomers are randomly distributed along the copolymer chain...
08/09/2005
6908594Efficient microfluidic sealing
Improved sealing for microstructures in microfluidic devices having a plurality of units is provided by providing collars surrounding the openings to the microstructures, such as reservoirs. The collars are protrusions extending from the surface of the devices and t...
06/21/2005
6878254Size separation of analytes using monomeric surfactants
A sieving medium for use in the separation of analytes in a sample containing at least one such analyte comprises a monomeric non-ionic surfactant of the of the general formula, B-A, wherein A is a hydrophilic moiety and B is a hydrophobic moiety, present in a solve...
04/12/2005
6878255Microfluidic devices with thick-film electrochemical detection
An apparatus for conducting a microfluidic process and analysis, including at least one elongated microfluidic channel, fluidic transport means for transport of fluids through the microfluidic channel, and at least one thick-film electrode in fluidic connection with...
04/12/2005
6837977Capillary electrophoresis method for screening for affinity ligands using a detectable competitive ligand
The invention relates to a capillary electrophoresis-based method of screening complex materials for any unidentified affinity ligand that binds to a target of interest. The method subjects a plug of a mixture of the target and a complex material sample, and a separ...
01/04/2005
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