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| Number | Title | Issue Date |
| 5358618 | Capillary electrophoresis apparatus with improved electroosmotic flow control An electrophoretic separation apparatus includes a capillary tube having a length, a cross section, an inlet and an outlet. A first reservoir containing a solvent and, upon injection, a solute is in fluid-flow communication with the inlet and a second res... | 10/25/1994 |
| 5358613 | Method and apparatus for injecting liquid into a capillary tube In a method and a corresponding apparatus for injecting liquid from a vial into a capillary tube, in particular in capillary electrophoresis, a source of overpressure and a source of underpressure are connectable to the vial for applying overpressure or u... | 10/25/1994 |
| 5358612 | Electrophoresis with chemically suppressed detection Improved capillary electrophoresis apparatus of the type that generally includes a capillary tube, the capillary tube having a sample inlet end and an outlet end, a first electrode in electrical communication with the inlet end of the capillary tube, a se... | 10/25/1994 |
| 5356525 | Sample handling system A sample handling system suitable for use with a sample segment and a plurality of capillaries, including a rotatable and vertically translatable arm including an attachment portion to removably receive and retain the sample segment and a manifold adapted... | 10/18/1994 |
| 5354440 | Capillary electrophoresis technique To detect bands in an electrophoresis capillary tube having a liquid separating medium, a light source and a light detector of a monitor are positioned on opposite sides of the capillary tube with the light source transmitting light through a first slit a... | 10/11/1994 |
| 5348658 | Process for effecting capillary electrophoresis An apparatus is provided for concentrating a solute sample which can be subsequently released for analysis by capillary electrophoresis. The apparatus comprises a tube containing a short length of packed particles or gel adapted to retain sample solutes w... | 09/20/1994 |
| 5340452 | On-column preconcentration of samples in capillary electrophoresis A electrophoresis column having on-column means and a method for concentrating analytes of interest in a sample prior to electrophoresis. The column comprises a section having the concentrating means upstream of a capillary section. A sample is flowed pas... | 08/23/1994 |
| 5338427 | Single use separation cartridge for a capillary electrophoresis instrument A disposable cartridge for a capillary electrophoresis instrument in which short capillary tube segments are used for simultaneous multiple lane separations. The cartridge contains all separation components of the instrument which come in contact with the... | 08/16/1994 |
| 5328578 | Capillary electrophoresis with tracking separation field A capillary electrophoresis system utilizes a square "ring" capillary. The capillary has a hair-pin bend at each corner of the square. An opening in each bend permits fluid and electrical coupling with a respective electrolyte-containing vial. A distribut... | 07/12/1994 |
| 5318680 | On-column derivatization in capillary electrophoresis An on-column derivatization scheme where a liquid or solid labeling reagent is provided in a capillary to react chemically with a sample in order to label the sample. Electrophoretic separation may be carried out immediately thereafter to simplify the der... | 06/07/1994 |
| 5298134 | Capillary device A cross or T-shaped device is disclosed for use in capillary electrophoresis or capillary chromatography. The device includes a first capillary tube and a second capillary tube connected to the first tube at a point between the two ends of the first tube ... | 03/29/1994 |
| 5246577 | Apparatus for effecting capillary electrophoresis An apparatus is provided for concentrating a solute sample which can be subsequently released for analysis by capillary electrophoresis. The apparatus comprises a tube containing a short length of packed particles or gel adapted to retain sample solutes w... | 09/21/1993 |
| 5240577 | Two-dimensional high-performance liquid chromatography/capillary electrophoresis Disclosed is a two-dimensional separation system, comprising a liquid chromatography column having an outlet port; a capillary electrophoresis capillary having an inlet end and an outlet end; buffer supply means for supplying buffer to the capillary; and ... | 08/31/1993 |
| 5240578 | Capillary electrophoresis system and method A capillary electrophoresis system has a sample tube from which a sample is injected into a capillary tube by introducing a gas thereinto through an on-off valve. In order to maintain its internal pressure constantly at a target level, the pressure inside... | 08/31/1993 |
| 5217590 | Method and apparatus for the introduction of a volume of at least one fluid in a tube in particular suitable for capillary electrophoresis systems and method and apparatus for separating and/or analyzing a fluid material A method and apparatus for the injection of a quantitatively defined volume of at least one fluid into a tube or capillary, in particular suitable for capillary electrophoresis systems by immersing at least one end of the tube or capillary in the fluid to... | 06/08/1993 |
| 5207886 | Capillary electrophoresis An apparatus is disclosed for providing capillary electrophoresis, which includes an electronically controlled valve system for automatically introducing a sample into the capillary by means of a vacuum at the end of the capillary tube. This approach of s... | 05/04/1993 |
| 5173163 | Capillary electrophoresis technique To inject sample into an electrophoresis capillary tube having a separating medium, the end of the capillary tube is inserted in an injection block with a liquid tight seal and a syringe is inserted into the block to apply fluid to the end of the capillar... | 12/22/1992 |
| 5141621 | Capillary electrophoresis injection device and method An apparatus and method useful for sample injection in capillary electrophoresis is disclosed. The apparatus comprises an interface device with capillary and tubing inserted therein. Sample is injected through the tubing into the interface and is thereaft... | 08/25/1992 |
| 5131998 | Two-dimensional high-performance liquid chromatography/capillary electrophoresis Disclosed is a two-dimensional separation system, comprising a liquid chromatography column having an outlet port; a capillary electrophoresis capillary having an inlet end and an outlet end; buffer supply means for supplying buffer to the capillary; and ... | 07/21/1992 |
| 5126023 | End-column electrical and electrochemical detector for capillary zone electrophoresis Electrical and electrochemical end-column detectors are provided in which the sensing microelectrode is placed at the outlet of the separation capillary. The novel design minimizes the electrical interference caused by the applied high voltage during CZE ... | 06/30/1992 |
| 5122248 | Pulsed field capillary electrophoresis Apparatus and method for conducting electrophoresis in a capillary tube under the influence of a pulsed electric field. Apparatus for separating and detecting molecular species of a sample in a conductive medium includes a capillary tube for containing co... | 06/16/1992 |
| 5120414 | Method and apparatus for effecting capillary sample injection into electrophoresis apparatus An electrode structure is provided for feeding a solute sample to a capillary electrophoresis separation process. The apparatus comprises a conductive plate connected to an electrical lead and an absorbent layer wet with an electrolyte solution and positi... | 06/09/1992 |
| 5116471 | System and method for improving sample concentration in capillary electrophoresis The method for improving sample concentration in capillary electrophoresis by extracting the sample buffer from the capillary column using the electro-osmotic flow while the sample components are stacked into the support buffer utilizes a system for this ... | 05/26/1992 |
| 5110431 | On-capillary gap junction for fluorescence detection in capillary electrophoresis A junction reactor that aligns a pair of capillaries substantially collinearly, end-to-end that allows a small gap to be produced between these two ends. An applied voltage difference between the other ends of these two capillaries produces in the gap ele... | 05/05/1992 |
| 5102517 | Capillary wash system A device and method for controlling capillary injection volume is disclosed. The device is a capillary surrounded at one end by an outer jacket which is filled with a wash liquid. The outer jacket and the capillary can move relative to each other along th... | 04/07/1992 |
| 5098539 | Gel-containing microcapillary column Disclosed is a gel-containing capillary column useful in high performance capillary electrophoresis. A preferred column includes a microcapillary having an interior cavity and a wall with an inner surface; a bifunctional agent comprising a positively char... | 03/24/1992 |
| 5089106 | High performance capillary gel electrophoresis An improved, highly stable capillary column used in high performance capillary electrophoresis and method of preparing the same. The improved capillary column can significantly reduce the effects of electroosmosis during electrophoresis, is stable for reu... | 02/18/1992 |
| 5073239 | Fluid introduction into a capillary by electroendosmosis Bulk fluid movement in a capillary column is achieved by creating electroendosmotic flow in a fluid passage outside the column, the fluid passage being joined to the column in a manner which causes the electroendosmotic flow to generate bulk flow in the c... | 12/17/1991 |
| 5009760 | System for measuring electrokinetic properties and for characterizing electrokinetic separations by monitoring current in electrophoresis The electroosmotic velocity of an electrolyte is determined by displacing the electrolyte which fills a capillary tube by a second electrolyte which has the same composition as the first electrolyte but of a different concentration. The current flowing th... | 04/23/1991 |
| 4994165 | Liquid junction coupling for capillary zone electrophoresis/ion spray spectrometry An improved capillary zone electrophoresis (CZE)/ mass spectrometer interface comprises a liquid junction adapted to makeup the volume/flow rate of the CZE column eluent stream to be more compatible with the ion spray LC/MS interface flow rates required b... | 02/19/1991 |
| 4959321 | Cell fusion apparatus Cell electrofusion apparatus, for example for the production of hybridomas, comprises a flow-through capillary (14) surrounded by a water-cooled jacket (16) and through which a physiologically normal medium (such as a tissue culture fluid) containing cell... | 09/25/1990 |
| 4911807 | Fractionation and sample loading by cassette in capillary electrophoresis Short capillary segments are introduced in succession into the current path of a capillary electrophoresis system, either at the downstream end of the separation capillary for purposes of collecting the eluting species in fractions, or at the upstream end... | 03/27/1990 |
| 4908116 | Capillary electrophoretic device employing structure permitting electrical contact through ionic movement A capillary tube has a structure in its wall that permits ions to flow but no substantial amount of electrolyte to move therethrough. The structure therefore permits electrical contact between the electrolyte inside the tube and the outside environment wi... | 03/13/1990 |
| 4705616 | Electrophoresis-mass spectrometry probe The invention involves a new technique for the separation of complex mixtures of chemicals, which utilizes a unique interface probe for conventional mass spectrometers which allows the electrophoretically separated compounds to be analyzed in real-time by... | 11/10/1987 |
| 4676897 | Solubilization chromatography In an apparatus for conducting solubilization chromatography wherein a solvent consisting of a buffer and ionized micells is allowed to flow through a capillary tube whose both ends are connected to the plus and minus sides, respectively, of a DC source, ... | 06/30/1987 |
| 4459198 | Electrophoretic apparatus An electrophoretic apparatus which is equipped with means for detecting that a zone of a certain kind of ion component passes through a predetermined position of a migration tube so that the electrophoresis is divided into two stages to effect a pre-separ... | 07/10/1984 |
| 3998719 | Isotachophoretic columns An improved isotachophoretic column for separating ions in a test sample is described. The column is formed from a main unitary insulating body, in which appropriate passages are formed to define (a) a pair of chambers for holding leading and lagging elec... | 12/21/1976 |
