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| Number | Title | Issue Date |
| 8043493 | Multi-capillary array electrophoresis device An electrophoresis apparatus includes a multi-capillary array having a liquid or solid disposed between the capillaries of the array. The liquid or solid exhibits a refractive index higher than that of air and less than that of water and reduces the amount of laser ... | 10/25/2011 |
| 8012328 | Non-fluidic micro-detection device and uses thereof The present invention provides a microchip for performing electrophoresis with pulsed amperometric detection (PAD) for the separation and detection of underivatized carbohydrates, amino acids, sulfur-containing antibiotics, etc. PAD allows for the direct detection o... | 09/06/2011 |
| 7879215 | Electrophoresis chip An electrophoresis chip is provided with a channel that is filled with a solution in which a sample is dissolved, the electrophoresis chip being configured to carry out electrophoresis by applying voltage along the channel in a state in which the channel is hermetic... | 02/01/2011 |
| 7691247 | Optical detection alignment coupling apparatus An apparatus for aligning a capillary column with one or more excitation fibers and with one or more optical lens elements for Capillary Electrophoresis. The apparatus includes two identical blocks having a plurality of grooves for positioning and aligning the capil... | 04/06/2010 |
| 7588672 | Optical lens system and method for microfluidic devices An apparatus for imaging one or more selected fluorescence indications from a microfluidic device. The apparatus includes an imaging path coupled to least one chamber in at least one microfluidic device. The imaging path provides for transmission of one or more fluo... | 09/15/2009 |
| 7513984 | Capillary array electrophoresis apparatus When irradiating laser beam from the side face of the capillary array, an optical axis of the laser beam is inclined in vertical direction with respect to a plane face formed by the capillary array, thus, reflection light by the capillary array and returning light i... | 04/07/2009 |
| 7497937 | Microfabricated chip and method of use A multiplexed, absorbance-based microfabricated chip electrophoresis system, microfabricated chip, and method of use are included for the detection and identification of protein species. The microfabricated chip electrophoresis system capable of analyzing multiple s... | 03/03/2009 |
| 7449097 | Electrophoretic mobility measuring apparatus The present invention provides an electrophoretic mobility measuring apparatus capable of conducting measurement with high sensitivity with optical attenuation reduced by incidence of light through the electrode face. This apparatus comprises a transparent electrode... | 11/11/2008 |
| 7445701 | Capillary array unit and electrophoresis based thereon A capillary array includes multiple capillaries and two holding substrates for arranging the aforementioned multiple capillaries in a substantially plane surface by sandwiching at least some of these capillaries mutually. One of the holding substrates has a detectio... | 11/04/2008 |
| 7438792 | Separation system with a sheath-flow supported electrochemical detector An electrochemical detector including side channels associated with a separation channel of a sample component separation apparatus is provided. The side channels of the detector, in one configuration, provide a sheath-flow for an analyte exiting the separation chan... | 10/21/2008 |
| 7439075 | Method and device for withdrawing suspended microparticles from a fluidic microsystem A method of discharging a fluid flow with suspended microparticles from a fluidic microsystem (10) is described, whereby the fluid flow converges with at least one output flow to form a discharge flow at the end of a discharge channel (14) of the micro... | 10/21/2008 |
| 7422672 | Capillary array apparatus, method of manufacturing the same, and electrophoresis analysis method An electrophoresis analysis method and apparatus capable of maintaining high reliability upon a repeated use of the same gel. A heat transfer medium selected from the group consisting of solids, liquids and gels is filled in substantially all of the gaps between the... | 09/09/2008 |
| 7419578 | Capillary electrophoresis apparatus A capillary array electrophoresis which can measure fluorescence of a number of capillaries at a time with high sensitivity and can automatically analyze a sample sequentially. An end edge as a sample dissolution edge of a number of capillaries is connected to a pol... | 09/02/2008 |
| 7419577 | Removal method for coating of polymer coated glass capillary tubing and polymer coated glass capillary tubing The present invention provides a method for producing a high-quality capillary tube used in an electrophoresis apparatus in a safe and inexpensive manner. A polymer coating on a capillary tube is converted into gas and removed through an oxidative reaction with oxyg... | 09/02/2008 |
| 7419576 | Analyzing apparatus One of the principal objects of the present invention is to realize, in a small scale and at a low cost, an analyzing apparatus that analyzes and manipulates a minute sample such as DNA. The analyzing apparatus 1 incorporates an optical system for measuring a... | 09/02/2008 |
| 7417418 | Thin film sensor An electrically operated, particle detecting, or characterizing, sensor structured as a thin film multilayer sandwich. Three or more electrodes are deposited onto thin layers of film, and stacked to form the sandwich. A representative stacking arrangement provides a... | 08/26/2008 |
| 7384527 | Electrophoresis apparatus and a plate therefor The invention provides an electrophoresis apparatus comprising an electrophoretic chamber containing at least on two-plate housing for a sieving matrix, each said at least one two-plate housing consisting of a cover plate and a plate for housing said sieving matrix,... | 06/10/2008 |
| 7361259 | Capillary array and electrophoresis apparatus, and method A capillary electrophoresis device including a capillary array, and a method of manufacturing the capillary array, are provided. During the manufacture of the capillary array, a plurality of capillaries are arranged in a substantially parallel arrangement and are fi... | 04/22/2008 |
| 7358052 | Catalytic amplification of multiplexed assay signals Methods, compositions, kits, and a system are disclosed for detecting one or more analytes in a sample. A mixture comprising the (i) sample, (ii) a first binding reagent comprising a cleavage-inducing moiety and a first binding agent specific for an analyte, and (ii... | 04/15/2008 |
| 7351375 | Implement and device for analysis The present invention relates to an analyzing implement (1) having a capillary for movement of a specimen liquid. The capillary has inner surfaces (21c, 32c) provided with a first and a second opposed electrodes opposed to each oth... | 04/01/2008 |
| 7344628 | Capillary electrophoresis-electrochemical detection microchip device and supporting circuits The present invention is a capillary electrophoresis device, comprising a substrate; a first channel in the substrate, and having a buffer arm and a detection arm; a second channel in the substrate intersecting the first channel, and having a sample arm and a waste ... | 03/18/2008 |
| 7329333 | Uniform laser excitation and detection in capillary array electrophoresis system and method A capillary electrophoresis system comprises capillaries positioned in parallel to each other forming a plane. The capillaries are configured to allow samples to migrate. A light source is configured to illuminate the capillaries and the samples therein. This causes... | 02/12/2008 |
| 7329388 | Electrophoresis apparatus having staggered passage configuration An electrophoresis apparatus is generally disclosed for sequentially analyzing a single sample or multiple samples having one or more analytes in high or low concentrations. The apparatus comprises a relatively large-bore transport capillary which intersects with a ... | 02/12/2008 |
| 7316770 | Method of electrophoresis, electrophoresis apparatus and capillary array A method of electrophoresis, an electrophoresis apparatus and a capillary array in which a fluorescently labelled sample is supplied into capillaries in a capillary array constituted by a plurality of capillaries and including a sample supply portion, an electrophor... | 01/08/2008 |
| 7315021 | Charged droplet spray probe An improved sample introduction probe is disclosed for the production of ions from liquid sample solutions in an electrospray ion source. Nebulization of a liquid sample emerging from the end of an inner flow tube is pneumatically assisted by gas flowing from the en... | 01/01/2008 |
| 7311882 | Capillary interconnect device A manifold for connecting external capillaries to the inlet and/or outlet ports of a microfluidic device for high pressure applications is provided. The fluid connector for coupling at least one fluid conduit to a corresponding port of a substrate that includes: (i)... | 12/25/2007 |
| 7312432 | Single axis illumination for multi-axis imaging system A single-axis illumination system for a multiple-axis imaging system, particularly an array microscope. A single-axis illumination system is used to trans-illuminate an object viewed with an array of imaging elements having multiple respective axes. The numerical ap... | 12/25/2007 |
| 7309409 | Multi-channel bio-separation cartridge A bio-separation system using an efficient, compact, portable, interchangeable, reusable, recyclable, multi-channel cartridge, has integrated pre-aligned optics and an integrated reagent reservoir. The cartridge supports, for example, multiple capillaries for CE sep... | 12/18/2007 |
| 7307802 | Optical lens system and method for microfluidic devices An apparatus for imaging one or more selected fluorescence indications from a microfluidic device. The apparatus includes an imaging path coupled to least one chamber in at least one microfluidic device. The imaging path provides for transmission of one or more fluo... | 12/11/2007 |
| 7293449 | Thermal modulation for gas chromatography A thermal modulator device for gas chromatography and associated methods. The thermal modulator device includes a recirculating fluid cooling member, an electrically conductive capillary in direct thermal contact with the cooling member, and a power supply electrica... | 11/13/2007 |
| 7282367 | Method for verifying amount of sample solution, method for controlling measurement system and method for measuring concentration of solution in apparatus for measuring optical characteristic A verification method of a sample solution amount includes the steps of: detecting at least one of a transmitted light component, a scattered light component and a reflected light component of a light by a photosensor while irradiating a sample solution, which is be... | 10/16/2007 |
| 7273517 | Non-planar microfabricated gas chromatography column A non-planar microfabricated gas chromatography column comprises a planar substrate having a plurality of through holes, a top lid and a bottom lid bonded to opposite surfaces of the planar substrate, and inlet and outlet ports for injection of a sample gas and elut... | 09/25/2007 |
| 7271895 | Fluorescent sensor on basis of multichannel structures Sensor for use in highly sensitive analytical devices for qualitative and quantitative analysis of natural waters and technology-related solutions, containing low concentrations of components determined. Design of a sensor provides for simplification and costs reduc... | 09/18/2007 |
| 7267948 | SERS diagnostic platforms, methods and systems microarrays, biosensors and biochips A Raman integrated sensor system for the detection of targets including biotargets includes at least one sampling platform, at least one receptor probe disposed on the sampling platform, and an integrated circuit detector system communicably connected to the recepto... | 09/11/2007 |
| 7267753 | Electrokinetic device having capacitive electrodes An electrokinetic device is capable of operating for extended periods of time, e.g. days to a week, without producing significant gaseous byproducts and without significant evolution of the pump fluid. Features of the electrokinetic device include: the electrodes in... | 09/11/2007 |
| 7262847 | Optical assembly and method for detection of light transmission An optical assembly comprising a light source, at least one sample vessel and a detector. The detector comprises a plurality of detector locations and the vessel comprises a wall and core of relative shape and dimensions adapted to contain a sample for detection and... | 08/28/2007 |
| 7258775 | Method and device for the qualitative and/or quantitative analysis of a protein and/or peptide pattern of a liquid sample that is derived from the human or animal body The invention relates to a method for the qualitative and/or quantitative analysis of a protein and/or peptide pattern of a liquid sample that is derived from the human or animal body. The proteins and peptides of the liquid sample are separated by capillary electro... | 08/21/2007 |
| 7255999 | Methods and compositions for analyzing proteins Methods, compositions and kits are disclosed for determining one or more target polypeptides in a sample where the target polypeptides have undergone a post-translational modification. A mixture comprising the sample and a first reagent comprising a cleavage-inducin... | 08/14/2007 |
| 7250099 | Optical detection alignment coupling apparatus An apparatus for aligning a capillary column with one or more excitation fibers and with one or more optical lens elements for Capillary Electrophoresis. The apparatus includes two identical blocks having a plurality of grooves for positioning and aligning the capil... | 07/31/2007 |
| 7250098 | Multi-capillary array electrophoresis device An electrophoresis apparatus includes a multi-capillary array having a liquid or solid disposed between the capillaries of the array. The liquid or solid exhibits a refractive index higher than that of air and less than that of water and reduces the amount of laser ... | 07/31/2007 |
