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| Number | Title | Issue Date |
| 8182669 | Dynamic equilibrium separation, concentration, and mixing apparatus and methods Particles are separated, concentrated, or mixed within a fluid by means of a fluid-containing cell having a longitudinal axis, a cross-sectional area generally perpendicular to the longitudinal axis, and at least one particle motivating force directionally interacti... | 05/22/2012 |
| 8147668 | Apparatus for manipulating droplets Apparatuses for mixing droplets, such as a binary mixing apparatus, are provided. The binary mixing apparatus includes an array of electrodes and a conducting element positioned in relation to at least one of the electrodes to enable a droplet placed in electrical c... | 04/03/2012 |
| 8137523 | Apparatus for and method of separating polarizable analyte using dielectrophoresis An apparatus separating a polarizable analyte using dielectrophoresis includes a vessel including a membrane having a plurality of nano- to micro-sized pores, the membrane disposed inside the vessel, electrodes generating spatially non-uniform electric fields in the... | 03/20/2012 |
| 8128797 | Microfluidic system and corresponding operating method The invention relates to an operating method for a microfluidic system, including the following steps: feeding of a carrier flow with particles (5) of a first particle type suspended therein into the microfluidic system; charging of a plurality of electrical ... | 03/06/2012 |
| 8118987 | Two-dimensional control of electrochemical surface potentials A method for providing a two dimensional spatially varying surface potential on a surface of a conductive substrate and use thereof. The method comprises providing a conductive substrate having a first conductive surface and comprising an array of“n” electrical ... | 02/21/2012 |
| 8097141 | Flow dielectrophoretic separation of single wall carbon nanotubes According to some embodiments, a method for separating a first fraction of a single wall carbon nanotubes and a second fraction of single wall carbon nanotubes includes, but is not limited to: flowing a solution comprising the nanotubes into a dielectrophoresis cham... | 01/17/2012 |
| 8088267 | Method and apparatus for electrokinetic transport Controlled electrokinetic transport of constituents of liquid media can be achieved by connecting at least two volumes containing liquid media with at least one dielectric medium with opposing dielectric surfaces in direct contact with said liquid media, and establi... | 01/03/2012 |
| 8083917 | Methods and apparatus for the location and concentration of polar analytes using an alternating electric field A method is disclosed for effecting the concentration of a polar analyte in an alternating electric field. In the method, a relative translation of the polar analyte and an alternating electric field along a translation path is effected. A portion of the polar analy... | 12/27/2011 |
| 8083916 | Detection device having increased detection rate, and method for quick detection of biological molecules A biological molecule detection device that includes a detection array, arranged on a body and having one or more probes for detecting corresponding electrically charged molecules, wherein a time varying electric field generating circuit is provided for generating a... | 12/27/2011 |
| 8029657 | Parallel plate electrodes for particle concentration or removal An AC electro-hydro-dynamic system for aggregating particles immersed in a fluid. The AC electro-hydro-dynamic system utilizes at least one set of parallel plate electrodes each having at least one conductive surface. The conductive surfaces may incorporate island c... | 10/04/2011 |
| 7988841 | Treatment of biological samples using dielectrophoresis A plurality of planar electrodes (5) in a microchannel (4) is used for separation, lysis and PCR in a chip (10). Cells from a sample are brought to the electrodes (5). Depending on sample properties, phase pattern, frequency and voltage o... | 08/02/2011 |
| 7959781 | Apparatus and method for manufacturing carbon nano-tube probe by using metallic vessel as an electrode The present invention provides an apparatus for manufacturing a carbon nano-tube tip comprising an AC/DC voltage supply, a metallic or semiconductor tip, an amperemeter, and a metallic vessel connected to the tip and the amperemter, wherein the metallic vessel is us... | 06/14/2011 |
| 7906003 | Subsea production system A well fluid processing system has a separator for separating heavier and lighter components of well fluid flowing from a subsea well and directing the lighter components to flow to a surface processing facility. The separator has a cylindrical chamber having a leng... | 03/15/2011 |
| 7897026 | Fluid particle separating device A fluid particle-separating device includes a sorting, first and second diverting channels, a detector, a microprocessor, first and second actuators, and first and second sieving valves. The sorting channel receives fluid containing first and second particles. The f... | 03/01/2011 |
| 7879214 | Method and device for collecting suspended particles A description is given of methods for collecting particles (1, 2) which are suspended in a liquid, including the following steps: providing the liquid containing the suspended particles (1, 2) in a compartment (10) having lateral surfaces (11... | 02/01/2011 |
| 7857956 | Systems and methods for making and using nanoelectrodes Systems and methods are provided for the manipulation of a polarizable object with a pair of elongated nanoelectrodes using dielectrophoresis. The nanoelectrodes can be carbon nanotubes and are coupled with one or more time-varying voltage sources to create an elect... | 12/28/2010 |
| 7744737 | Microfluidic device for the assembly and transport of microparticles A microfluidic device comprising independently addressable arrays of interdigitated electrodes can be used to assembly and transport large-scale microparticle structures. The device and method uses collective phenomena in a negatively polarized suspension exposed to... | 06/29/2010 |
| 7704362 | Apparatus for transport and analysis of particles using dielectrophoresis Dielectrophoresis is used to attract particles to an electrode edge then to controllably allow the transport of particles along that edge under a fluid flow to a particular region. The particles may be bacteria which may be maintained in this process in a live state... | 04/27/2010 |
| 7704363 | Methods and apparatus for the location and concentration of polar analytes using an alternating electric field A method is disclosed for effecting the concentration of a polar analyte in an alternating electric field. In the method, a relative translation of the polar analyte and an alternating electric field along a translation path is effected. A portion of the polar analy... | 04/27/2010 |
| 7699969 | Method and apparatus for high-throughput biological-activity screening of cells and/or compounds First entities consisting in cells or microorganisms (BIO) and second entities consisting in compounds or compound units, carried typically by microbeads (BEAD), are trapped selectively within closed movable potential cages (S1) by means of dielectrophoretic ... | 04/20/2010 |
| 7686934 | Three dimensional dielectrophoretic separator and methods of use Devices and methods for performing separation of cell particles by dielectrophoresis in three dimensions. In one embodiment the device comprises a flow chamber having microfabricated chip with a plurality of vertical and horizontal electrodes, which may be coated wi... | 03/30/2010 |
| 7678256 | Insulator-based DEP with impedance measurements for analyte detection Disclosed herein are microfluidic devices for assaying at least one analyte specie in a sample comprising at least one analyte concentration area in a microchannel having insulating structures on or in at least one wall of the microchannel which provide a nonuniform... | 03/16/2010 |
| 7658829 | Integrated microfluidic transport and sorting system The invention integrates a two-stage dielectrophoretic (DEP) droplet dispensing and distribution system with particulate DEP to create a novel LOC platform capable of manipulating biological cells based on the varied dielectrophoretic signatures that distinguish cel... | 02/09/2010 |
| 7641779 | Method and apparatus for programmable fluidic processing A method and apparatus for microfluidic processing by programmably manipulating a packet. A material is introduced onto a reaction surface and compartmentalized to form a packet. A position of the packet is sensed with a position sensor. A programmable manipulation ... | 01/05/2010 |
| 7635420 | Dielectrophoresis-based particle sensor using nanoelectrode arrays A method for concentrating or partly separating particles of a selected species from a liquid or fluid containing these particles and flowing in a channel, and for determining if the selected species particle is present in the liquid or fluid. A time varying electri... | 12/22/2009 |
| 7547380 | Droplet transportation devices and methods having a fluid surface Devices for the manipulation of a suspended particle in an electric field gradient include a plurality of electrically isolated electrodes on a surface. A liquid composition is on the plurality of electrodes. The liquid composition covers the surface continuously be... | 06/16/2009 |
| 7534334 | Apparatus and method for concentrating and filtering particles suspended in a fluid Disclosed is a device for separating and concentrating particles suspended in a fluid stream by using dielectrophoresis (DEP) to trap and/or deflect those particles as they migrate through a fluid channel. The method uses fluid channels designed to constrain a liqui... | 05/19/2009 |
| 7488406 | Apparatus for collecting particles Detail is apparatus for collecting particles from a liquid, including a first electrode having an upper surface defining one or more substantially circular areas of a predetermined diameter separated from a counter electrode, having an uppersurface bounding at least... | 02/10/2009 |
| 7455758 | Fluidic microsystem comprising field-forming passivation layers provided on microelectrodes Described is a fluidic microsystem (100) including at least one channel (10) through which a particle suspension can flow; and first and second electrode devices (40, 60) which are arranged on first and second channel walls (21, 31) for g... | 11/25/2008 |
| 7425253 | Microscale sorting cytometer The present invention provides a device and methods of use thereof in microscale cell sorting. This invention provides sorting cytometers, which trap individual cells within vessels following exposure to dielectrophoresis, allow for the assaying of trapped cells, su... | 09/16/2008 |
| 7419574 | Dielectrophoresis device and method having non-uniform arrays for manipulating particles Microfluidic devices according to embodiments of the present invention include an inlet port, an outlet port, and a channel or chamber having a non-uniform array of insulating features on one or more surfaces. Electrodes are provided for generation of a spatially no... | 09/02/2008 |
| 7413891 | Apparatus and method for detecting live cells with an integrated filter and growth detection device A device for processing fluids includes a filter to capture a cell sample. The filter has a physical barrier to isolate the cell sample on the filter. Growth detection circuitry is associated with the filter. The growth detection circuitry identifies, through electr... | 08/19/2008 |
| 7390387 | Method of sorting cells in series A method of sorting cells comprises providing a fluid flow path for cell movement through a series of cell sorters in a first direction with an output of a preceding cell sorter of the series communicating with an input of a successive cell sorter of the series. Wit... | 06/24/2008 |
| 7390388 | Method of sorting cells on a biodevice A method of sorting cells for a biodevice comprises directing a flow of cells within a fluid into a filtration structure defining an array of fluid openings and encouraging cell passage of each cell of a portion of the cells through the fluid openings based on at le... | 06/24/2008 |
| 7384791 | Method of analyzing blood A method of analyzing blood includes delivering a blood sample to a test device, applying a spatially varying electric field to the blood sample to provide a depleted cell concentration in a portion of the blood sample, and sensing a property of the portion of the b... | 06/10/2008 |
| 7354733 | Method for sorting and separating living cells We disclose methods of sorting or separating mixtures of living cells (e.g., eukaryotic, prokaryotic, mammalian, pathogenic, bacterial, viral, etc.). We perform our methods by activating cell-selective photophoric labels, which photosensitize and chemically reduce a... | 04/08/2008 |
| 7347923 | Dielectrophoresis device and method having insulating ridges for manipulating particles Embodiments of the present invention provide methods and devices for manipulating particles using dielectrophoresis. Insulating ridges and valleys are used to generate a spatially non-uniform electrical field. Particles may be concentrated, separated, or captured du... | 03/25/2008 |
| 7341864 | Molecule transferring device, auxiliary for molecule transferring device, and molecule transferring method A molecule introducing apparatus is provided with a power supply circuit 20 for supplying power, a step-up transformer 30 which is supplied with power from the power supply circuit 20 and which outputs a high voltage, a switching transistor 2... | 03/11/2008 |
| 7329545 | Methods for sampling a liquid flow In a method for sampling a continuous liquid flow, the liquid flow is supplied to a surface along an input flow path. The liquid flow is sampled by forming a sample droplet from a portion of the liquid flow. The sample droplet is moved along an analysis flow path to... | 02/12/2008 |
| 7323140 | Moving microdroplets in a microfluidic device The present invention relates to a system and method for moving samples, such as fluid, within a microfluidic system using a plurality of gas actuators for applying pressure at different locations within the microfluidic. The system includes a substrate which forms ... | 01/29/2008 |
